The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
AC IMMUNE SA SHS H00263105 869 274,876 SH   SOLE   274,876 0 0
ACADIA HEALTHCARE COMPANY IN COM 00404A109 108,608 1,389,200 SH   SOLE   1,389,200 0 0
AKERO THERAPEUTICS INC COM 00973Y108 106,304 3,122,000 SH   SOLE   3,122,000 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 57,746 288,500 SH   SOLE   288,500 0 0
ALPHATEC HLDGS INC COM NEW 02081G201 14,989 1,715,000 SH   SOLE   1,715,000 0 0
ALPINE IMMUNE SCIENCES INC COM 02083G100 7,190 998,600 SH   SOLE   998,600 0 0
ALTIMMUNE INC COM NEW 02155H200 34,275 2,684,000 SH   SOLE   2,684,000 0 0
AN2 THERAPEUTICS INC COM 037326105 12,907 742,630 SH   SOLE   742,630 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106 57,645 844,000 SH   SOLE   844,000 0 0
ARCUTIS BIOTHERAPEUTICS INC COM 03969K108 15,183 794,500 SH   SOLE   794,500 0 0
ARGENX SE SPONSORED ADR 04016X101 173,630 491,800 SH   SOLE   491,800 0 0
ARROWHEAD PHARMACEUTICALS IN COM 04280A100 41,490 1,255,374 SH   SOLE   1,255,374 0 0
ARVINAS INC COM 04335A105 193,242 4,343,500 SH   SOLE   4,343,500 0 0
ARYA SCIENCES ACQU CORP IV CL A G31659108 4,955 500,000 SH   SOLE   500,000 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108 30,886 563,200 SH   SOLE   563,200 0 0
AVANTOR INC COM 05352A100 88,643 4,522,600 SH   SOLE   4,522,600 0 0
AVIDITY BIOSCIENCES INC COM 05370A108 42,458 2,600,000 SH   SOLE   2,600,000 0 0
AXSOME THERAPEUTICS INC COM 05464T104 68,652 1,538,600 SH   SOLE   1,538,600 0 0
BCLS ACQUISITION CORP COM CL A G0904B105 5,010 500,000 SH   SOLE   500,000 0 0
BEIGENE LTD SPONSORED ADR 07725L102 17,796 132,000 SH   SOLE   132,000 0 0
BELLUS HEALTH INC NEW COM NEW 07987C204 45,901 4,346,700 SH   SOLE   4,346,700 0 0
BIO RAD LABS INC CL A 090572207 60,402 144,800 SH   SOLE   144,800 0 0
BIOGEN INC COM 09062X103 160,200 600,000 SH   SOLE   600,000 0 0
BOSTON SCIENTIFIC CORP COM 101137107 98,320 2,538,600 SH   SOLE   2,538,600 0 0
CAREMAX INC COM CL A 14171W103 5,355 755,329 SH   SOLE   755,329 0 0
CARIBOU BIOSCIENCES INC COM 142038108 33,471 3,172,600 SH   SOLE   3,172,600 0 0
CATALENT INC COM 148806102 68,018 940,000 SH   SOLE   940,000 0 0
CENTENE CORP DEL COM 15135B101 33,645 432,400 SH   SOLE   432,400 0 0
CENTURY THERAPEUTICS INC COM 15673T100 12,893 1,303,600 SH   SOLE   1,303,600 0 0
COGENT BIOSCIENCES INC COM 19240Q201 20,257 1,357,700 SH   SOLE   1,357,700 0 0
COMPASS THERAPEUTICS INC COM 20454B104 4,560 2,000,000 SH   SOLE   2,000,000 0 0
CYTEIR THERAPEUTICS INC COM 23284P103 3,468 1,806,200 SH   SOLE   1,806,200 0 0
CYTOKINETICS INC COM NEW 23282W605 16,231 335,000 SH   SOLE   335,000 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 22,048 1,191,800 SH   SOLE   1,191,800 0 0
DEXCOM INC COM 252131107 37,661 467,600 SH   SOLE   467,600 0 0
ELEVANCE HEALTH INC COM 036752103 94,300 207,600 SH   SOLE   207,600 0 0
ERASCA INC COM 29479A108 7,664 982,500 SH   SOLE   982,500 0 0
ESSA PHARMA INC COM NEW 29668H708 4,477 2,460,000 SH   SOLE   2,460,000 0 0
GOSSAMER BIO INC COM 38341P102 17,371 1,450,000 SH   SOLE   1,450,000 0 0
GRAPHITE BIO INC COM 38870X104 4,993 1,575,000 SH   SOLE   1,575,000 0 0
HEALTH SCIENCES ACQ CORP 2 ORD SHS G4411D109 3,960 400,000 SH   SOLE   400,000 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 91,733 1,482,200 SH   SOLE   1,482,200 0 0
HUMANA INC COM 444859102 102,860 212,000 SH   SOLE   212,000 0 0
HYPERFINE INC COM CL A 44916K106 1,218 1,503,754 SH   SOLE   1,503,754 0 0
IDEAYA BIOSCIENCES INC COM 45166A102 55,434 3,715,400 SH   SOLE   3,715,400 0 0
IMMUNOCORE HLDGS PLC ADS 45258D105 97,593 2,079,100 SH   SOLE   2,079,100 0 0
INTELLIA THERAPEUTICS INC COM 45826J105 55,910 999,100 SH   SOLE   999,100 0 0
INTRA-CELLULAR THERAPIES INC COM 46116X101 65,258 1,402,500 SH   SOLE   1,402,500 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100 13,248 1,382,900 SH   SOLE   1,382,900 0 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105 42,426 318,300 SH   SOLE   318,300 0 0
KARUNA THERAPEUTICS INC COM 48576A100 97,125 431,800 SH   SOLE   431,800 0 0
KEZAR LIFE SCIENCES INC COM 49372L100 46,618 5,414,400 SH   SOLE   5,414,400 0 0
KINNATE BIOPHARMA INC COM 49705R105 14,491 1,212,611 SH   SOLE   1,212,611 0 0
LILLY ELI & CO COM 532457108 325,613 1,007,000 SH   SOLE   1,007,000 0 0
MEDICUS SCIENCES ACQUISITION *W EXP 02/12/202 G5960S124 1 57,770 SH   SOLE   57,770 0 0
MEDICUS SCIENCES ACQUISITION CL A SHS G5960S108 5,148 520,000 SH   SOLE   520,000 0 0
NANOSTRING TECHNOLOGIES INC COM 63009R109 8,916 698,200 SH   SOLE   698,200 0 0
NATERA INC COM 632307104 76,028 1,735,000 SH   SOLE   1,735,000 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 197,094 1,855,700 SH   SOLE   1,855,700 0 0
NGM BIOPHARMACEUTICALS INC COM 62921N105 23,519 1,798,100 SH   SOLE   1,798,100 0 0
NKARTA INC COM 65487U108 18,609 1,414,082 SH   SOLE   1,414,082 0 0
NUVATION BIO INC *W EXP 07/07/202 67080N119 18 99,999 SH   SOLE   99,999 0 0
ONCOSEC MED INC COM 68234L306 1,437 2,945,000 SH   SOLE   2,945,000 0 0
PANACEA ACQUISITION CORP II CL A SHS G6882C106 4,900 500,000 SH   SOLE   500,000 0 0
PHASEBIO PHARMACEUTICALS INC COM 717224109 768 4,361,365 SH   SOLE   4,361,365 0 0
PHATHOM PHARMACEUTICALS INC COM 71722W107 21,127 1,906,800 SH   SOLE   1,906,800 0 0
PLIANT THERAPEUTICS INC COM 729139105 41,385 1,981,100 SH   SOLE   1,981,100 0 0
POINT BIOPHARMA GLOBAL INC COM 730541109 21,799 2,820,000 SH   SOLE   2,820,000 0 0
PROTHENA CORP PLC SHS G72800108 119,259 1,967,000 SH   SOLE   1,967,000 0 0
REUNION NEUROSCIENCE INC COM 76134G103 851 595,200 SH   SOLE   595,200 0 0
REVOLUTION MEDICINES INC COM 76155X100 45,774 2,321,200 SH   SOLE   2,321,200 0 0
SANGAMO THERAPEUTICS INC COM 800677106 11,568 2,360,800 SH   SOLE   2,360,800 0 0
SAREPTA THERAPEUTICS INC COM 803607100 104,814 948,200 SH   SOLE   948,200 0 0
SCIENCE 37 HOLDINGS INC COM 808644108 692 430,000 SH   SOLE   430,000 0 0
SCYNEXIS INC COM NEW 811292200 2,737 1,140,600 SH   SOLE   1,140,600 0 0
SEAGEN INC COM 81181C104 60,958 445,500 SH   SOLE   445,500 0 0
SEASPINE HLDGS CORP COM 81255T108 11,417 2,010,000 SH   SOLE   2,010,000 0 0
SEMA4 HOLDINGS CORP COM CL A 81663L101 834 950,000 SH   SOLE   950,000 0 0
SI-BONE INC COM 825704109 17,402 996,700 SH   SOLE   996,700 0 0
SOCIAL CAP SUVRETTA HLDS CP CLASS A ORD SHS G8253Y105 1,964 200,000 SH   SOLE   200,000 0 0
SOCIAL CAP SUVRETTA HLDS CRP CLASS A ORD SHS G8253U103 1,960 200,000 SH   SOLE   200,000 0 0
SPDR SER TR S&P BIOTECH 78464A870 117,394 1,480,000 SH   SOLE   1,480,000 0 0
SPDR SER TR CALL 78464A900 158,719 2,001,000 SH Call SOLE   2,001,000 0 0
SPDR SER TR CALL 78464A900 162,685 2,051,000 SH Call SOLE   2,051,000 0 0
STOKE THERAPEUTICS INC COM 86150R107 11,442 891,100 SH   SOLE   891,100 0 0
STRYKER CORPORATION COM 863667101 37,409 184,700 SH   SOLE   184,700 0 0
SURGERY PARTNERS INC COM 86881A100 6,262 267,600 SH   SOLE   267,600 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105 134,253 5,586,900 SH   SOLE   5,586,900 0 0
SYROS PHARMACEUTICALS INC COM NEW 87184Q206 5,796 900,000 SH   SOLE   900,000 0 0
TANGO THERAPEUTICS INC COM 87583X109 2,946 813,700 SH   SOLE   813,700 0 0
TRANSMEDICS GROUP INC COM 89377M109 12,522 300,000 SH   SOLE   300,000 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 84,957 2,051,600 SH   SOLE   2,051,600 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102 203,140 970,200 SH   SOLE   970,200 0 0
VAXCYTE INC COM 92243G108 15,089 628,700 SH   SOLE   628,700 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 148,476 512,800 SH   SOLE   512,800 0 0
VERVE THERAPEUTICS INC COM 92539P101 35,817 1,042,706 SH   SOLE   1,042,706 0 0
ZAI LAB LTD ADR 98887Q104 42,203 1,234,000 SH   SOLE   1,234,000 0 0
ZENTALIS PHARMACEUTICALS INC COM 98943L107 91,472 4,223,100 SH   SOLE   4,223,100 0 0