The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| 2SEVENTY BIO INC | COMMON STOCK | 901384107 | 7,715 | 530,223 | SH | DFND | 6 | 530,223 | 0 | 0 | |
| AKOUOS INC | COM | 00973J101 | 8,709 | 1,288,358 | SH | DFND | 6 | 1,288,358 | 0 | 0 | |
| COMPASS THERAPEUTICS INC | COM | 20454B104 | 6,452 | 2,829,712 | SH | DFND | 6 | 2,829,712 | 0 | 0 | |
| CORVUS PHARMACEUTICALS INC | COM | 221015100 | 1,952 | 2,384,402 | SH | DFND | 6 | 2,384,402 | 0 | 0 | |
| CULLINAN ONCOLOGY INC | COM | 230031106 | 41,578 | 3,243,185 | SH | DFND | 6 | 3,243,185 | 0 | 0 | |
| DIREXION SHS ETF TR | DAILY S&P BIOTEC | 25460G716 | 1,197 | 50,000 | SH | DFND | 6 | 50,000 | 0 | 0 | |
| EIGER BIOPHARMACEUTICALS INC | COM | 28249U105 | 3,427 | 455,100 | SH | DFND | 6 | 455,100 | 0 | 0 | |
| FREELINE THERAPEUTICS HLDGS | SPONSORED ADS | 35655L107 | 3,370 | 4,814,419 | SH | DFND | 6 | 4,814,419 | 0 | 0 | |
| G1 THERAPEUTICS INC | COM | 3621LQ109 | 4,046 | 323,945 | SH | DFND | 6 | 323,945 | 0 | 0 | |
| IKENA ONCOLOGY INC | COM | 45175G108 | 4,311 | 1,214,304 | SH | DFND | 6 | 1,214,304 | 0 | 0 | |
| INOZYME PHARMA INC | COM | 45790W108 | 5,350 | 1,996,277 | SH | DFND | 6 | 1,996,277 | 0 | 0 | |
| KEROS THERAPEUTICS INC | COM | 492327101 | 7,533 | 200,229 | SH | DFND | 6 | 200,229 | 0 | 0 | |
| KEZAR LIFE SCIENCES INC | COM | 49372L100 | 15,178 | 1,762,793 | SH | DFND | 6 | 1,762,793 | 0 | 0 | |
| LARIMAR THERAPEUTICS INC | COM | 517125100 | 10,928 | 3,415,148 | SH | DFND | 6 | 3,415,148 | 0 | 0 | |
| NKARTA INC | COM | 65487U108 | 1,548 | 117,599 | SH | DFND | 6 | 117,599 | 0 | 0 | |
| OMEGA THERAPEUTICS INC | COMMON STOCK | 68217N105 | 5,723 | 1,055,882 | SH | DFND | 6 | 1,055,882 | 0 | 0 | |
| ONCORUS INC | COM | 68236R103 | 2,012 | 2,367,436 | SH | DFND | 6 | 2,367,436 | 0 | 0 | |
| ORCHARD THERAPEUTICS PLC | SPON ADS | 68570P101 | 3,994 | 7,987,396 | SH | DFND | 6 | 7,987,396 | 0 | 0 | |
| OVID THERAPEUTICS INC | COM | 690469101 | 1,591 | 864,822 | SH | DFND | 6 | 864,822 | 0 | 0 | |
| PLIANT THERAPEUTICS INC | COM | 729139105 | 71,230 | 3,409,758 | SH | DFND | 6 | 3,409,758 | 0 | 0 | |
| PRECISION BIOSCIENCES INC | COM | 74019P108 | 4,777 | 3,674,820 | SH | DFND | 6 | 3,674,820 | 0 | 0 | |
| PROMETHEUS BIOSCIENCES INC | COM | 74349U108 | 94,521 | 1,601,785 | SH | DFND | 6 | 1,601,785 | 0 | 0 | |
| RALLYBIO CORP | COM | 75120L100 | 2,811 | 194,297 | SH | DFND | 6 | 194,297 | 0 | 0 | |
| REPARE THERAPEUTICS INC | COM | 760273102 | 37,237 | 3,069,847 | SH | DFND | 6 | 3,069,847 | 0 | 0 | |
| VECTIVBIO HLDG AG | ORD SHS | H9060V101 | 24,717 | 4,119,572 | SH | DFND | 6 | 4,119,572 | 0 | 0 | |