The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Abeona Therapeutics Inc COM 00289Y107 461 2,215,740 SH   SOLE   2,215,740 0 0
Advanced Micro Devices Inc COM 007903107 627 8,200 SH   SOLE   8,200 0 0
Aldeyra Therapeutics Inc COM 01438T106 5,995 1,502,460 SH   SOLE   1,502,460 0 0
Altimmune Inc COM NEW 02155H200 1,556 132,978 SH   SOLE   132,978 0 0
Altria Group Inc COM 02209S103 948 22,700 SH   SOLE   22,700 0 0
Angion BioMedica Corp COM 03476J107 68 60,000 SH   SOLE   60,000 0 0
Anavex Life Sciences Corp COM NEW 003279730 2,110 210,789 SH   SOLE   210,789 0 0
Annovis Bio Inc COM 03615A108 161 14,210 SH   SOLE   14,210 0 0
Applied Genetic Technologies COM 03820J100 77 100,000 SH   SOLE   100,000 0 0
Applied Therapeutics Inc COM 03828A101 1,026 1,082,123 SH   SOLE   1,082,123 0 0
Arista Networks Inc COM 040413106 1,294 13,800 SH   SOLE   13,800 0 0
ASML Holdings NY REGISTRY SHS N07059210 609 1,280 SH   SOLE   1,280 0 0
Biohaven Pharmactl Hldg Co L COM G11196105 131,406 900,844 SH   SOLE   900,844 0 0
Bioxcel Therapeutics Inc COM 09075P105 92 20,000 SH   SOLE   20,000 0 0
Blackstone Group LP COM UNIT LTD 09253U108 1,461 16,000 SH   SOLE   16,000 0 0
Booz Allen Hamilton HLDG COR CL A 099502106 1,175 13,000 SH   SOLE   13,000 0 0
Context Therapeutics Ins COM 21077P108 296 139,520 SH   SOLE   139,520 0 0
Corbus Pharmaceuticals HLDGS COM 21833P103 1,273 5,045,870 SH   SOLE   5,045,870 0 0
Corning Inc COM 219350105 838 26,600 SH   SOLE   26,600 0 0
CVS Health Corp COM 126650100 1,344 14,500 SH   SOLE   14,500 0 0
Eiger Biopharmaceuticals Inc COM 28249U105 4,374 694,232 SH   SOLE   694,232 0 0
Entera Bio Ltd SHS M40527109 3,304 2,484,275 SH   SOLE   2,484,275 0 0
Lumen Technologies Inc COM 156700106 1,091 100,000 SH   SOLE   100,000 0 0
Mirati Therapeutics, Inc COM 60468T105 336 5,000 SH   SOLE   5,000 0 0
Oramed Pharmaceuticals Inc COM NEW 68403P203 92 20,000 SH   SOLE   20,000 0 0
Orgenesis, Inc. COM 68619K105 3,186 1,316,364 SH   SOLE   1,316,364 0 0
Spero Therapeutics Inc COM 84833T103 52 70,000 SH   SOLE   70,000 0 0
Soligenix Inc. COM 834223307 163 271,580 SH   SOLE   271,580 0 0
Thermo Fischer Scientific Inc COM 883556102 1,141 2,100 SH   SOLE   2,100 0 0
Visa COM CL A 92826C839 955 4,850 SH   SOLE   4,850 0 0
FRANCO NEV CORP COM 351858105 645 4,900 SH   SOLE   4,900 0 0
MAVERIX METALS INC COM NEW 57776F405 718 165,000 SH   SOLE   165,000 0 0
AGNICO EAGLE MINES LTD COM 008474108 704 15,393 SH   SOLE   15,393 0 0
EQUINOX GOLD CORP COM 29446Y502 971 99,000 SH   SOLE   99,000 0 0
SEABRIDGE GOLD INC COM 811916105 398 32,000 SH   SOLE   32,000 0 0
OSISKO GOLD ROYALTIES LTD COM 68827L101 676 235,000 SH   SOLE   235,000 0 0
MAG SILVER CORP COM 55903Q104 584 17,300 SH   SOLE   17,300 0 0
Wheaton Precious metals COM 962879102 594 16,500 SH   SOLE   16,500 0 0
PAN AMERN SILVER CORP COM 697900108 849 29,500 SH   SOLE   29,500 0 0
SILVERCREST METALS INC COM 828363101 861 100,000 SH   SOLE   100,000 0 0
OSHKOSH CORP COM 688239201 694 8,450 SH   SOLE   8,450 0 0