The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
908 DEVICES INC COM 65443P102 6,101 296,288 SH   SOLE   296,288 0 0
AMERISOURCEBERGEN CORP PUT 03073E955 4,952 35,000 SH Put SOLE   35,000 0 0
ABIOMED INC PUT 003654950 6,188 25,000 SH Put SOLE   25,000 0 0
ABBOTT LABS PUT 002824950 21,730 200,000 SH Put SOLE   200,000 0 0
ACADIA PHARMACEUTICALS INC CALL 004225908 2,818 200,000 SH Call SOLE   0 0 0
ADAPTIVE BIOTECHNOLOGIES COR COM 00650F109 1,214 150,000 SH   SOLE   150,000 0 0
AGILON HEALTH INC COM 00857U107 5,154 236,100 SH   SOLE   236,100 0 0
ALCON AG PUT H01301958 9,435 135,000 SH Put SOLE   135,000 0 0
ALIGN TECHNOLOGY INC PUT 016255951 13,017 55,000 SH Put SOLE   55,000 0 0
ALNYLAM PHARMACEUTICALS INC PUT 02043Q957 7,293 50,000 SH Put SOLE   50,000 0 0
ALNYLAM PHARMACEUTICALS INC CALL 02043Q907 3,690 25,300 SH Call SOLE   0 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 13,891 95,240 SH   SOLE   95,240 0 0
ALPHA TEKNOVA INC COM 02080L102 2,109 251,112 SH   SOLE   251,112 0 0
AMYRIS INC CALL 03236M900 3,258 1,761,000 SH Call SOLE   0 0 0
AMYLYX PHARMACEUTICALS INC COM 03237H101 203 10,550 SH   SOLE   10,550 0 0
AMYRIS INC COM NEW 03236M200 1,943 1,050,399 SH   SOLE   1,050,399 0 0
APELLIS PHARMACEUTICALS INC CALL 03753U906 9,044 200,000 SH Call SOLE   0 0 0
APOLLO ENDOSURGERY INC COM 03767D108 1,559 427,057 SH   SOLE   427,057 0 0
APYX MEDICAL CORPORATION CALL 03837C906 1,758 300,000 SH Call SOLE   0 0 0
APYX MEDICAL CORPORATION COM 03837C106 7,755 1,323,303 SH   SOLE   1,323,303 0 0
ARCUTIS BIOTHERAPEUTICS INC COM 03969K108 2,131 100,000 SH   SOLE   100,000 0 0
ARK ETF TR PUT 00214Q952 26,767 850,000 SH Put SOLE   850,000 0 0
ARK ETF TR CALL 00214Q904 7,976 200,000 SH Call SOLE   0 0 0
ARK ETF TR PUT 00214Q954 17,946 450,000 SH Put SOLE   450,000 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108 10,758 162,828 SH   SOLE   162,828 0 0
ATHIRA PHARMA INC COM 04746L104 818 268,131 SH   SOLE   268,131 0 0
ATARA BIOTHERAPEUTICS INC CALL 046513907 1,558 200,000 SH Call SOLE   0 0 0
ATRICURE INC COM 04963C209 4,356 106,615 SH   SOLE   106,615 0 0
AVADEL PHARMACEUTICALS PLC SPONSORED ADR 05337M104 1,926 789,181 SH   SOLE   789,181 0 0
AVANTOR INC COM 05352A100 4,821 155,000 SH   SOLE   155,000 0 0
AVITA MEDICAL INC COM 05380C102 3,524 741,875 SH   SOLE   741,875 0 0
ANAVEX LIFE SCIENCES CORP CALL 032797900 2,002 200,000 SH Call SOLE   0 0 0
THE BEAUTY HEALTH COMPANY COM CL A 88331L108 3,922 305,000 SH   SOLE   305,000 0 0
BELLUS HEALTH INC NEW COM NEW 07987C204 1,127 122,000 SH   SOLE   122,000 0 0
BAUSCH HEALTH COS INC PUT 071734957 2,508 300,000 SH Put SOLE   300,000 0 0
BICYCLE THERAPEUTICS PLC SPONSORED ADS 088786108 3,073 183,121 SH   SOLE   183,121 0 0
BIOGEN INC CALL 09062X903 71,155 348,900 SH Call SOLE   0 0 0
BIOCRYST PHARMACEUTICALS INC COM 09058V103 3,854 364,252 SH   SOLE   364,252 0 0
BIOGEN INC COM 09062X103 20,743 101,711 SH   SOLE   101,711 0 0
BIOVENTUS INC COM CL A 09075A108 4,086 599,080 SH   SOLE   599,080 0 0
BRISTOL-MYERS SQUIBB CO PUT 110122958 15,400 200,000 SH Put SOLE   200,000 0 0
BIONTECH SE CALL 09075V902 11,928 80,000 SH Call SOLE   0 0 0
BLUEPRINT MEDICINES CORP PUT 09627Y959 505 10,000 SH Put SOLE   10,000 0 0
CEREVEL THERAPEUTICS HLDNG I CALL 15678U908 6,435 243,400 SH Call SOLE   0 0 0
CANOPY GROWTH CORP PUT 138035950 9,975 3,500,000 SH Put SOLE   3,500,000 0 0
CHIMERIX INC COM 16934W106 801 384,905 SH   SOLE   384,905 0 0
CELLDEX THERAPEUTICS INC NEW CALL 15117B902 16,036 594,800 SH Call SOLE   0 0 0
CELLDEX THERAPEUTICS INC NEW PUT 15117B952 2,696 100,000 SH Put SOLE   100,000 0 0
CLOVIS ONCOLOGY INC CALL 189464900 511 284,000 SH Call SOLE   0 0 0
CODEXIS INC COM 192005106 3,527 337,154 SH   SOLE   337,154 0 0
COGENT BIOSCIENCES INC COM 19240Q201 2,154 238,787 SH   SOLE   238,787 0 0
CONCERT PHARMACEUTICALS INC COM 206022105 187 44,357 SH   SOLE   44,357 0 0
COOPER COS INC COM NEW 216648402 10,176 32,500 SH   SOLE   32,500 0 0
CORTEXYME INC CALL 22053A907 444 200,000 SH Call SOLE   0 0 0
CUTERA INC COM 232109108 41,931 1,118,158 SH   SOLE   1,118,158 0 0
CUTERA INC CALL 232109908 1,875 50,000 SH Call SOLE   0 0 0
CYTEK BIOSCIENCES INC COM 23285D109 5,120 477,164 SH   SOLE   477,164 0 0
CYTOKINETICS INC NOTE 4.000%11/1 23282WAA8 9,702 25,000 PRN   SOLE   25,000 0 0
GINKGO BIOWORKS HOLDINGS INC PUT 37611X950 4,165 1,750,000 SH Put SOLE   1,750,000 0 0
DEXCOM INC PUT 252131957 7,006 94,000 SH Put SOLE   94,000 0 0
EDWARDS LIFESCIENCES CORP COM 28176E108 1,968 20,700 SH   SOLE   20,700 0 0
ESPERION THERAPEUTICS INC NE COM 29664W105 1,349 212,123 SH   SOLE   212,123 0 0
ESTABLISHMENT LABS HLDGS INC COM G31249108 53,766 988,713 SH   SOLE   988,713 0 0
EVOLENT HEALTH INC CL A 30050B101 7,063 230,000 SH   SOLE   230,000 0 0
EXACT SCIENCES CORP PUT 30063P955 3,939 100,000 SH Put SOLE   100,000 0 0
EXACT SCIENCES CORP CALL 30063P905 5,318 135,000 SH Call SOLE   0 0 0
EXELIXIS INC COM 30161Q104 1,562 75,000 SH   SOLE   75,000 0 0
FIRST TR EXCHANGE TRADED FD PUT 33734X953 34,030 330,000 SH Put SOLE   330,000 0 0
GERON CORP CALL 374163903 2,639 1,702,600 SH Call SOLE   0 0 0
GUARDANT HEALTH INC CALL 40131M909 18,758 465,000 SH Call SOLE   0 0 0
GUARDANT HEALTH INC PUT 40131M959 2,824 70,000 SH Put SOLE   70,000 0 0
GH RESEARCH PLC ORDINARY SHARES G3855L106 2,081 208,527 SH   SOLE   208,527 0 0
GLAUKOS CORP CALL 377322902 5,905 130,000 SH Call SOLE   0 0 0
GLAUKOS CORP COM 377322102 36,182 796,600 SH   SOLE   796,600 0 0
GLOBAL BLOOD THERAPEUTICS IN COM 37890U108 462 14,454 SH   SOLE   14,454 0 0
GOSSAMER BIO INC PUT 38341P952 837 100,000 SH Put SOLE   100,000 0 0
GOSSAMER BIO INC NOTE 5.000% 6/0 38341PAA0 374 5,000 PRN   SOLE   5,000 0 0
GOSSAMER BIO INC COM 38341P102 677 80,878 SH   SOLE   80,878 0 0
GUARDANT HEALTH INC COM 40131M109 18,939 469,492 SH   SOLE   469,492 0 0
HCA HEALTHCARE INC PUT 40412C951 8,403 50,000 SH Put SOLE   50,000 0 0
HEALTH SCIENCES ACQ CORP 2 ORD SHS G4411D109 1,036 104,026 SH   SOLE   104,026 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 1,029 12,900 SH   SOLE   12,900 0 0
HEALTHEQUITY INC CALL 42226A907 15,348 250,000 SH Call SOLE   0 0 0
HENRY SCHEIN INC PUT 806407952 5,372 70,000 SH Put SOLE   70,000 0 0
HUMANA INC COM 444859102 2,996 6,400 SH   SOLE   6,400 0 0
INTEGRA LIFESCIENCES HLDGS C PUT 457985958 6,694 123,900 SH Put SOLE   123,900 0 0
ICAD INC COM NEW 44934S206 2,692 672,989 SH   SOLE   672,989 0 0
IDEXX LABS INC PUT 45168D954 29,812 85,000 SH Put SOLE   85,000 0 0
ISHARES TR PUT 464288950 58,006 1,150,000 SH Put SOLE   1,150,000 0 0
ILLUMINA INC PUT 452327959 11,062 60,000 SH Put SOLE   60,000 0 0
IMMUNOCORE HLDGS PLC ADS 45258D105 239 6,419 SH   SOLE   6,419 0 0
IMMUNIC INC PUT 4525EP951 1,164 335,500 SH Put SOLE   335,500 0 0
INMODE LTD PUT M5425M953 4,706 210,000 SH Put SOLE   210,000 0 0
INSPIRE MED SYS INC COM 457730109 37,350 204,465 SH   SOLE   204,465 0 0
INSULET CORP COM 45784P101 2,179 10,000 SH   SOLE   10,000 0 0
IOVANCE BIOTHERAPEUTICS INC CALL 462260900 2,208 200,000 SH Call SOLE   0 0 0
IRHYTHM TECHNOLOGIES INC COM 450056106 5,402 50,000 SH   SOLE   50,000 0 0
IVERIC BIO INC CALL 46583P902 7,019 729,600 SH Call SOLE   0 0 0
IVERIC BIO INC PUT 46583P952 327 34,000 SH Put SOLE   34,000 0 0
INTUITIVE SURGICAL INC CALL 46120E902 8,028 40,000 SH Call SOLE   0 0 0
IVERIC BIO INC COM 46583P102 6,880 715,144 SH   SOLE   715,144 0 0
ISHARES TR PUT 464287955 118,552 700,000 SH Put SOLE   700,000 0 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105 3,377 21,643 SH   SOLE   21,643 0 0
KALVISTA PHARMACEUTICALS INC COM 483497103 7,998 812,828 SH   SOLE   812,828 0 0
KARUNA THERAPEUTICS INC COM 48576A100 3,783 29,900 SH   SOLE   29,900 0 0
ORTHOPEDIATRICS CORP PUT 68752L950 4,962 115,000 SH Put SOLE   115,000 0 0
KARUNA THERAPEUTICS INC CALL 48576A900 392 3,100 SH Call SOLE   0 0 0
KARUNA THERAPEUTICS INC PUT 48576A950 3,226 25,500 SH Put SOLE   25,500 0 0
LANTHEUS HLDGS INC COM 516544103 14,014 212,238 SH   SOLE   212,238 0 0
LIVANOVA PLC SHS G5509L101 16,045 256,848 SH   SOLE   256,848 0 0
LIVANOVA PLC CALL G5509L901 54,293 869,100 SH Call SOLE   0 0 0
LIQUIDIA CORPORATION PUT 53635D952 1,023 234,700 SH Put SOLE   234,700 0 0
LUCIRA HEALTH INC COM 54948U105 1,285 690,663 SH   SOLE   690,663 0 0
LEXICON PHARMACEUTICALS INC CALL 528872902 167 89,900 SH Call SOLE   0 0 0
LYRA THERAPEUTICS INC COM 55234L105 14,556 2,576,196 SH   SOLE   2,576,196 0 0
MEDTRONIC PLC PUT G5960L953 24,233 270,000 SH Put SOLE   270,000 0 0
MEDPACE HLDGS INC PUT 58506Q959 10,477 70,000 SH Put SOLE   70,000 0 0
METACRINE INC COM 59101E103 99 198,230 SH   SOLE   198,230 0 0
MILESTONE PHARMACEUTICALS IN COM 59935V107 6,073 987,411 SH   SOLE   987,411 0 0
METTLER TOLEDO INTERNATIONAL PUT 592688955 20,103 17,500 SH Put SOLE   17,500 0 0
NANOSTRING TECHNOLOGIES INC COM 63009R109 18,663 1,469,547 SH   SOLE   1,469,547 0 0
NATERA INC COM 632307104 2,132 60,159 SH   SOLE   60,159 0 0
NEKTAR THERAPEUTICS CALL 640268908 139 36,600 SH Call SOLE   0 0 0
NANOSTRING TECHNOLOGIES INC CALL 63009R909 6,350 500,000 SH Call SOLE   0 0 0
INTELLIA THERAPEUTICS INC CALL 45826J905 2,588 50,000 SH Call SOLE   0 0 0
INTELLIA THERAPEUTICS INC PUT 45826J955 10,083 194,800 SH Put SOLE   194,800 0 0
NOVOCURE LTD PUT G6674U958 6,255 90,000 SH Put SOLE   90,000 0 0
NYXOAH S A SHS B6S7WD106 2,185 221,949 SH   SOLE   221,949 0 0
OLINK HLDG AB CALL 680710900 8,968 590,000 SH Call SOLE   0 0 0
OUTSET MED INC CALL 690145907 8,886 598,000 SH Call SOLE   0 0 0
ONCOCYTE CORP COM 68235C107 16,245 18,056,274 SH   SOLE   18,056,274 0 0
OUTSET MED INC COM 690145107 6,593 443,701 SH   SOLE   443,701 0 0
PACIFIC BIOSCIENCES CALIF IN PUT 69404D958 7,293 1,650,000 SH Put SOLE   1,650,000 0 0
PENUMBRA INC PUT 70975L957 15,565 125,000 SH Put SOLE   125,000 0 0
PHATHOM PHARMACEUTICALS INC COM 71722W107 864 102,328 SH   SOLE   102,328 0 0
KONINKLIJKE PHILIPS N V PUT 500472953 4,306 200,000 SH Put SOLE   200,000 0 0
PERKINELMER INC PUT 714046959 15,644 110,000 SH Put SOLE   110,000 0 0
PLIANT THERAPEUTICS INC CALL 729139905 801 100,000 SH Call SOLE   0 0 0
VANECK ETF TRUST PUT 92189F952 23,052 300,000 SH Put SOLE   300,000 0 0
PRIVIA HEALTH GROUP INC COM 74276R102 5,191 178,255 SH   SOLE   178,255 0 0
PRIVIA HEALTH GROUP INC CALL 74276R902 15,288 525,000 SH Call SOLE   0 0 0
PTC THERAPEUTICS INC NOTE 3.000% 8/1 69366JAB7 2,026 20,000 PRN   SOLE   20,000 0 0
PTC THERAPEUTICS INC CALL 69366J900 2,928 73,100 SH Call SOLE   0 0 0
PULMONX CORP COM 745848101 19,534 1,327,065 SH   SOLE   1,327,065 0 0
QUANTERIX CORP COM 74766Q101 7,083 437,500 SH   SOLE   437,500 0 0
QUOTIENT LTD SHS G73268107 1,599 6,662,019 SH   SOLE   6,662,019 0 0
R1 RCM INC COM 77634L105 5,234 249,732 SH   SOLE   249,732 0 0
AVITA MEDICAL INC CALL 05380C902 2,138 450,000 SH Call SOLE   0 0 0
RADIUS HEALTH INC PUT 750469957 1,236 119,200 SH Put SOLE   119,200 0 0
RENOVACOR INC *W EXP 99/99/999 75989E114 8 150,632 SH   SOLE   150,632 0 0
RENOVACOR INC COM 75989E106 294 144,925 SH   SOLE   144,925 0 0
REPLIGEN CORP PUT 759916959 4,060 25,000 SH Put SOLE   25,000 0 0
RELMADA THERAPEUTICS INC PUT 75955J952 1,158 61,000 SH Put SOLE   61,000 0 0
ROIVANT SCIENCES LTD *W EXP 09/30/202 G76279119 120 199,648 SH   SOLE   199,648 0 0
SAVARA INC COM 805111101 144 95,014 SH   SOLE   95,014 0 0
SCHRODINGER INC COM 80810D103 1,321 50,000 SH   SOLE   50,000 0 0
SCIENCE 37 HOLDINGS INC COM 808644108 2,224 1,106,400 SH   SOLE   1,106,400 0 0
SCHRODINGER INC CALL 80810D903 4,886 185,000 SH Call SOLE   0 0 0
SEER INC CALL 81578P906 3,133 350,000 SH Call SOLE   0 0 0
THE BEAUTY HEALTH COMPANY CALL 88331L908 1,286 100,000 SH Call SOLE   0 0 0
SOMALOGIC INC CALL 83444K905 2,737 605,500 SH Call SOLE   0 0 0
SOMALOGIC INC *W EXP 08/31/202 83444K113 155 204,401 SH   SOLE   204,401 0 0
SOMALOGIC INC CLASS A COM 83444K105 9,597 2,123,120 SH   SOLE   2,123,120 0 0
SONENDO INC COM 835431107 1,760 1,023,424 SH   SOLE   1,023,424 0 0
SOPHIA GENETICS SA ORDINARY SHARES H82027105 3,113 859,930 SH   SOLE   859,930 0 0
SPRINGBIG HOLDINGS INC *W EXP 06/14/202 85021Q116 1 10,000 SH   SOLE   10,000 0 0
SAREPTA THERAPEUTICS INC CALL 803607900 14,992 200,000 SH Call SOLE   0 0 0
STAAR SURGICAL CO COM PAR $0.01 852312305 13,889 195,810 SH   SOLE   195,810 0 0
STANDARD BIOTOOLS INC COM 34385P108 1,360 850,000 SH   SOLE   850,000 0 0
STRYKER CORPORATION PUT 863667951 58,684 295,000 SH Put SOLE   295,000 0 0
TALKSPACE INC *W EXP 06/21/202 87427V111 149 427,194 SH   SOLE   427,194 0 0
MOLSON COORS BEVERAGE CO PUT 60871R959 14,080 258,300 SH Put SOLE   258,300 0 0
TRICIDA INC CALL 89610F901 3,079 318,100 SH Call SOLE   0 0 0
TELA BIO INC COM 872381108 3,895 555,623 SH   SOLE   555,623 0 0
TELEFLEX INCORPORATED PUT 879369956 6,146 25,000 SH Put SOLE   25,000 0 0
TG THERAPEUTICS INC COM 88322Q108 4,041 950,813 SH   SOLE   950,813 0 0
TG THERAPEUTICS INC PUT 88322Q958 1,577 371,000 SH Put SOLE   371,000 0 0
TANDEM DIABETES CARE INC PUT 875372953 9,470 160,000 SH Put SOLE   160,000 0 0
TRAVERE THERAPEUTICS INC COM 89422G107 4,027 166,201 SH   SOLE   166,201 0 0
TRAVERE THERAPEUTICS INC NOTE 2.250% 3/0 89422GAA5 502 5,000 PRN   SOLE   5,000 0 0
TRICIDA INC COM 89610F101 483 49,900 SH   SOLE   49,900 0 0
TRUPANION INC PUT 898202956 6,568 109,000 SH Put SOLE   109,000 0 0
10X GENOMICS INC PUT 88025U959 11,313 250,000 SH Put SOLE   250,000 0 0
UNITY BIOTECHNOLOGY INC CALL 91381U901 442 783,800 SH Call SOLE   0 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102 14,292 60,650 SH   SOLE   60,650 0 0
UNITY BIOTECHNOLOGY INC COM 91381U101 202 359,089 SH   SOLE   359,089 0 0
UNIVERSE PHARMACEUTICALS INC SHS G9442G104 150 239,482 SH   SOLE   239,482 0 0
VERASTEM INC COM 92337C104 1,165 1,004,272 SH   SOLE   1,004,272 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 4,724 16,763 SH   SOLE   16,763 0 0
VERU INC CALL 92536C903 2,260 200,000 SH Call SOLE   0 0 0
VIEWRAY INC COM 92672L107 36,753 13,869,108 SH   SOLE   13,869,108 0 0
VINCERX PHARMA INC COM NEW 92731L106 143 108,459 SH   SOLE   108,459 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104 1,220 105,460 SH   SOLE   105,460 0 0
WALGREENS BOOTS ALLIANCE INC PUT 931427958 5,685 150,000 SH Put SOLE   150,000 0 0
WM TECHNOLOGY INC *W EXP 06/16/202 92971A117 33 50,000 SH   SOLE   50,000 0 0
SPDR SER TR CALL 78464A900 7,368 99,200 SH Call SOLE   0 0 0
SPDR SER TR PUT 78464A950 37,135 500,000 SH Put SOLE   500,000 0 0
XENON PHARMACEUTICALS INC COM 98420N105 1,217 40,002 SH   SOLE   40,002 0 0
ZIMMER BIOMET HOLDINGS INC PUT 98956P952 5,253 50,000 SH Put SOLE   50,000 0 0
ZYMEWORKS INC COM 98985W102 237 44,696 SH   SOLE   44,696 0 0
ATAI LIFE SCIENCES NV SHS N0731H103 2,627 721,824 SH   SOLE   721,824 0 0
MEDAVAIL HOLDINGS INC COM 58406B103 1,093 714,120 SH   SOLE   714,120 0 0
STRYVE FOODS INC CLASS A COM 863685103 705 800,000 SH   SOLE   800,000 0 0