The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABBVIE INC COM 00287Y109 43,312 282,792 SH   DFND 1 282,792 0 0
ACADIA HEALTHCARE COMPANY IN COM 00404A109 77,858 1,151,232 SH   DFND 1 1,151,232 0 0
ACUITY BRANDS INC COM 00508Y102 335 2,175 SH   DFND 1 2,175 0 0
ADDUS HOMECARE CORP COM 006739106 28,840 346,297 SH   DFND 1 346,297 0 0
ADICET BIO INC COM 007002108 22,538 1,543,670 SH   DFND 1 1,543,670 0 0
ADOBE SYSTEMS INCORPORATED COM 00724F101 85,203 232,756 SH   DFND 1 232,756 0 0
ADVANCED MICRO DEVICES INC COM 007903107 276,374 3,614,153 SH   DFND 1 3,614,153 0 0
AEVA TECHNOLOGIES INC COM 00835Q103 71 22,601 SH   DFND 1 22,601 0 0
AEYE INC CL A COM 008183105 31 16,327 SH   DFND 1 16,327 0 0
AFFILIATED MANAGERS GROUP IN COM 008252108 17,935 153,819 SH   DFND 1 153,819 0 0
AFLAC INC COM 001055102 31,815 575,000 SH   DFND 1 575,000 0 0
AIR PRODS & CHEMS INC COM 009158106 1,510 6,279 SH   DFND 1 6,279 0 0
AIR TRANS SVCS GROUP INC NOTE 1.125%10/1 00922RAB1 21,272 19,615,000 SH   DFND 1 19,615,000 0 0
AIRBNB INC COM CL A 009066101 51,249 575,315 SH   DFND 1 575,315 0 0
AKOYA BIOSCIENCES INC COM 00974H104 16,904 1,315,470 SH   DFND 1 1,315,470 0 0
ALARM COM HLDGS INC COM 011642105 206 3,329 SH   DFND 1 3,329 0 0
ALBEMARLE CORP COM 012653101 5,458 26,115 SH   DFND 1 26,115 0 0
ALCON AG ORD SHS H01301128 25,340 362,824 SH   DFND 1 362,824 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 139,574 1,227,782 SH   DFND 1 1,227,782 0 0
ALLEGO N V ORD SHS N0796A100 90 17,756 SH   DFND 1 17,756 0 0
ALLEGRO MICROSYSTEMS INC COM 01749D105 414 20,033 SH   DFND 1 20,033 0 0
ALLSCRIPTS HEALTHCARE SOLUTN COM 01988P108 164 11,080 SH   DFND 1 11,080 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 31,078 213,079 SH   DFND 1 213,079 0 0
ALPHABET INC CAP STK CL A 02079K305 302,675 138,889 SH   DFND 1 138,889 0 0
ALPHABET INC CAP STK CL C 02079K107 336,036 153,620 SH   DFND 1 153,620 0 0
ALTAIR ENGR INC COM CL A 021369103 437 8,326 SH   DFND 1 8,326 0 0
ALTUS POWER INC COM CL A 02217A102 65 10,292 SH   DFND 1 10,292 0 0
AMAZON COM INC COM 023135106 132,982 1,252,066 SH   DFND 1 1,252,066 0 0
AMBARELLA INC SHS G037AX101 32,343 494,095 SH   DFND 1 494,095 0 0
AMEDISYS INC COM 023436108 2,691 25,604 SH   DFND 1 25,604 0 0
AMETEK INC COM 031100100 21,372 194,481 SH   DFND 1 194,481 0 0
AMGEN INC COM 031162100 6,987 28,717 SH   DFND 1 28,717 0 0
ANALOG DEVICES INC COM 032654105 25,122 171,963 SH   DFND 1 171,963 0 0
ANGIODYNAMICS INC COM 03475V101 36,228 1,872,236 SH   DFND 1 1,872,236 0 0
ANSYS INC COM 03662Q105 1,295 5,410 SH   DFND 1 5,410 0 0
AON PLC SHS CL A G0403H108 97,085 360,000 SH   DFND 1 360,000 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106 312 6,900 SH   DFND 1 6,900 0 0
APPLE INC COM 037833100 581,162 4,250,747 SH   DFND 1 4,250,747 0 0
APPLIED MATLS INC COM 038222105 15,969 175,525 SH   DFND 1 175,525 0 0
APTARGROUP INC COM 038336103 48,996 474,723 SH   DFND 1 474,723 0 0
APTIV PLC SHS G6095L109 838 9,403 SH   DFND 1 9,403 0 0
ARCH CAP GROUP LTD ORD G0450A105 240,919 5,296,085 SH   DFND 1 5,296,085 0 0
ARCHER AVIATION INC COM CL A 03945R102 77 25,064 SH   DFND 1 25,064 0 0
ARCO PLATFORM LTD COM CL A G04553106 10,800 723,405 SH   DFND 1 723,405 0 0
ARCUTIS BIOTHERAPEUTICS INC COM 03969K108 29,958 1,405,796 SH   DFND 1 1,405,796 0 0
ARES CAPITAL CORP COM 04010L103 4,624 257,893 SH   DFND 1 257,893 0 0
ARISTA NETWORKS INC COM 040413106 125,008 1,333,564 SH   DFND 1 1,333,564 0 0
ARRAY TECHNOLOGIES INC COM SHS 04271T100 1,673 151,981 SH   DFND 1 151,981 0 0
ARRIVAL GROUP SHS L0423Q108 105 66,714 SH   DFND 1 66,714 0 0
ARROWHEAD PHARMACEUTICALS IN COM 04280A100 605 17,182 SH   DFND 1 17,182 0 0
ATLASSIAN CORP PLC CL A G06242104 20,686 110,382 SH   DFND 1 110,382 0 0
ATRICURE INC COM 04963C209 21,609 528,858 SH   DFND 1 528,858 0 0
AURORA INNOVATION INC CLASS A COM 051774107 179 93,789 SH   DFND 1 93,789 0 0
AUTODESK INC COM 052769106 664 3,864 SH   DFND 1 3,864 0 0
AVADEL PHARMACEUTICALS PLC SPONSORED ADR 05337M104 6,862 2,812,490 SH   DFND 1 2,812,490 0 0
AVANTOR INC COM 05352A100 62,765 2,018,178 SH   DFND 1 2,018,178 0 0
AXON ENTERPRISE INC COM 05464C101 12,793 137,310 SH   DFND 1 137,310 0 0
AXONICS INC COM 05465P101 40,255 710,336 SH   DFND 1 710,336 0 0
AZENTA INC COM 114340102 647 8,975 SH   DFND 1 8,975 0 0
BAKER HUGHES COMPANY CL A 05722G100 11,204 388,099 SH   DFND 1 388,099 0 0
BALLARD PWR SYS INC NEW COM 058586108 372 51,251 SH   DFND 1 51,251 0 0
BANK OF NT BUTTERFIELD&SON L SHS NEW G0772R208 7,930 254,235 SH   DFND 1 254,235 0 0
BELLUS HEALTH INC NEW COM NEW 07987C204 32,340 3,500,000 SH   DFND 1 3,500,000 0 0
BERKLEY W R CORP COM 084423102 123,209 1,805,000 SH   DFND 1 1,805,000 0 0
BERKSHIRE HATHAWAY INC DEL CL B NEW 084670702 86,154 315,559 SH   DFND 1 315,559 0 0
BILIBILI INC NOTE 1.375% 4/0 090040AB2 3,216 2,500,000 SH   DFND 1 2,500,000 0 0
BILL COM HLDGS INC COM 090043100 7,103 64,609 SH   DFND 1 64,609 0 0
BIO RAD LABS INC CL A 090572207 56,954 115,059 SH   DFND 1 115,059 0 0
BIOGEN INC COM 09062X103 35,690 175,000 SH   DFND 1 175,000 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 18,646 225,000 SH   DFND 1 225,000 0 0
BIOMEA FUSION INC COM 09077A106 397 33,155 SH   DFND 1 33,155 0 0
BIRD GLOBAL INC COM CL A 09077J107 13 28,973 SH   DFND 1 28,973 0 0
BK OF AMERICA CORP COM 060505104 27,520 884,050 SH   DFND 1 884,050 0 0
BLACKLINE INC NOTE 3/1 09239BAD1 23,910 30,000,000 SH   DFND 1 30,000,000 0 0
BLACKROCK INC COM 09247X101 548 900 SH   DFND 1 900 0 0
BLACKSTONE INC COM 09260D107 6,087 66,722 SH   DFND 1 66,722 0 0
BLOCK INC CL A 852234103 9,931 161,588 SH   DFND 1 161,588 0 0
BLOCK INC NOTE 5/0 852234AJ2 5,572 7,000,000 SH   DFND 1 7,000,000 0 0
BLOOM ENERGY CORP COM CL A 093712107 195 11,844 SH   DFND 1 11,844 0 0
BOOKING HOLDINGS INC COM 09857L108 20,225 11,564 SH   DFND 1 11,564 0 0
BORGWARNER INC COM 099724106 788 23,626 SH   DFND 1 23,626 0 0
BOSTON SCIENTIFIC CORP COM 101137107 82,414 2,211,268 SH   DFND 1 2,211,268 0 0
BROADCOM INC COM 11135F101 723 1,488 SH   DFND 1 1,488 0 0
CANADIAN NAT RES LTD COM 136385101 21,548 349,202 SH   DFND 1 349,202 0 0
CANNAE HLDGS INC COM 13765N107 13,060 675,275 SH   DFND 1 675,275 0 0
CANOO INC COM CL A 13803R102 47 25,218 SH   DFND 1 25,218 0 0
CARRIER GLOBAL CORPORATION COM 14448C104 665 18,637 SH   DFND 1 18,637 0 0
CASTLE BIOSCIENCES INC COM 14843C105 1,075 48,985 SH   DFND 1 48,985 0 0
CATALENT INC COM 148806102 4,912 45,779 SH   DFND 1 45,779 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 17,454 647,420 SH   DFND 1 647,420 0 0
CENOVUS ENERGY INC COM 15135U109 22,308 1,021,087 SH   DFND 1 1,021,087 0 0
CENTENE CORP DEL COM 15135B101 21,099 249,371 SH   DFND 1 249,371 0 0
CEREVEL THERAPEUTICS HLDNG I COM 15678U128 13,220 500,000 SH   DFND 1 500,000 0 0
CERIDIAN HCM HLDG INC NOTE 0.250% 3/1 15677JAD0 2,777 3,500,000 SH   DFND 1 3,500,000 0 0
CERUS CORP COM 157085101 9,898 1,870,990 SH   DFND 1 1,870,990 0 0
CHARGEPOINT HOLDINGS INC COM CL A 15961R105 804 58,705 SH   DFND 1 58,705 0 0
CHART INDS INC COM 16115Q308 1,051 6,277 SH   DFND 1 6,277 0 0
CHEMED CORP NEW COM 16359R103 5,996 12,773 SH   DFND 1 12,773 0 0
CHUBB LIMITED COM H1467J104 215,112 1,094,274 SH   DFND 1 1,094,274 0 0
CITIZENS FINL GROUP INC COM 174610105 9,582 268,478 SH   DFND 1 268,478 0 0
CITRIX SYS INC COM 177376100 665 6,840 SH   DFND 1 6,840 0 0
CLOUDFLARE INC CL A COM 18915M107 13,458 307,621 SH   DFND 1 307,621 0 0
COGNEX CORP COM 192422103 2,686 63,173 SH   DFND 1 63,173 0 0
CONSTELLIUM SE CL A SHS F21107101 195 14,784 SH   DFND 1 14,784 0 0
COOPER COS INC COM NEW 216648402 42,370 135,317 SH   DFND 1 135,317 0 0
COUPA SOFTWARE INC NOTE 0.375% 6/1 22266LAF3 18,498 24,500,000 SH   DFND 1 24,500,000 0 0
COUPA SOFTWARE INC NOTE 0.125% 6/1 22266LAC0 3,737 4,500,000 SH   DFND 1 4,500,000 0 0
COURSERA INC COM 22266M104 7,234 510,170 SH   DFND 1 510,170 0 0
CROWDSTRIKE HLDGS INC CL A 22788C105 139,914 830,054 SH   DFND 1 830,054 0 0
CS DISCO INC COM 126327105 6,038 334,708 SH   DFND 1 334,708 0 0
CUMMINS INC COM 231021106 949 4,906 SH   DFND 1 4,906 0 0
CVS HEALTH CORP COM 126650100 62,913 678,970 SH   DFND 1 678,970 0 0
CYBERARK SOFTWARE LTD SHS M2682V108 90,066 703,864 SH   DFND 1 703,864 0 0
CYBERARK SOFTWARE LTD NOTE 11/1 23248VAB1 3,182 3,000,000 SH   DFND 1 3,000,000 0 0
CYTOKINETICS INC COM NEW 23282W605 118,917 3,026,648 SH   DFND 1 3,026,648 0 0
DANA INC COM 235825205 217 15,413 SH   DFND 1 15,413 0 0
DAY ONE BIOPHARMACEUTICALS I COM 23954D109 17,393 971,696 SH   DFND 1 971,696 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 19,725 1,500,000 SH   DFND 1 1,500,000 0 0
DEERE & CO COM 244199105 4,479 14,956 SH   DFND 1 14,956 0 0
DEXCOM INC NOTE 0.250%11/1 252131AK3 1,380 1,500,000 SH   DFND 1 1,500,000 0 0
DROPBOX INC NOTE 3/0 26210CAC8 8,150 9,000,000 SH   DFND 1 9,000,000 0 0
EAST WEST BANCORP INC COM 27579R104 9,925 153,156 SH   DFND 1 153,156 0 0
EATON CORP PLC SHS G29183103 665 5,275 SH   DFND 1 5,275 0 0
EDWARDS LIFESCIENCES CORP COM 28176E108 8,997 94,614 SH   DFND 1 94,614 0 0
ELASTIC N V ORD SHS N14506104 72,981 1,078,482 SH   DFND 1 1,078,482 0 0
ELECTRAMECCANICA VEHS CORP COM NEW 284849205 16 12,139 SH   DFND 1 12,139 0 0
ELEVANCE HEALTH INC COM 036752103 24,054 49,844 SH   DFND 1 49,844 0 0
EMBARK TECHNOLOGY INC COM 29079J103 19 38,279 SH   DFND 1 38,279 0 0
EMERSON ELEC CO COM 291011104 13,189 165,812 SH   DFND 1 165,812 0 0
ENCORE CAP EUROPE FIN LTD NOTE 4.500% 9/0 29260UAA5 3,114 2,250,000 SH   DFND 1 2,250,000 0 0
ENERSYS COM 29275Y102 1,073 18,202 SH   DFND 1 18,202 0 0
ENOVIX CORPORATION COM 293594107 230 25,761 SH   DFND 1 25,761 0 0
ENPHASE ENERGY INC COM 29355A107 69,942 358,235 SH   DFND 1 358,235 0 0
ENTERPRISE FINL SVCS CORP COM 293712105 7,268 175,141 SH   DFND 1 175,141 0 0
ENVISTA HOLDINGS CORPORATION COM 29415F104 63,809 1,655,656 SH   DFND 1 1,655,656 0 0
ESQUIRE FINL HLDGS INC COM 29667J101 703 21,123 SH   DFND 1 21,123 0 0
ESS TECH INC COMMON STOCK 26916J106 30 10,561 SH   DFND 1 10,561 0 0
ESSENT GROUP LTD COM G3198U102 119,909 3,082,500 SH   DFND 1 3,082,500 0 0
ESTABLISHMENT LABS HLDGS INC COM G31249108 320 5,891 SH   DFND 1 5,891 0 0
EVEREST RE GROUP LTD COM G3223R108 75,676 270,000 SH   DFND 1 270,000 0 0
EVGO INC CL A COM 30052F100 274 45,537 SH   DFND 1 45,537 0 0
EVOLENT HEALTH INC CL A 30050B101 1,259 41,008 SH   DFND 1 41,008 0 0
EXACT SCIENCES CORP NOTE 0.375% 3/0 30063PAC9 1,730 2,500,000 SH   DFND 1 2,500,000 0 0
EXELIXIS INC COM 30161Q104 48,080 2,309,299 SH   DFND 1 2,309,299 0 0
FARADAY FUTRE INTLGT ELCTR I COM 307359109 89 34,255 SH   DFND 1 34,255 0 0
FERGUSON PLC NEW SHS G3421J106 4,099,948 275,127 SH   DFND 1 275,127 0 0
FIRST AMERN FINL CORP COM 31847R102 52,920 1,000,000 SH   DFND 1 1,000,000 0 0
FIRST REP BK SAN FRANCISCO C COM 33616C100 7,009 48,607 SH   DFND 1 48,607 0 0
FIRST SOLAR INC COM 336433107 483 7,084 SH   DFND 1 7,084 0 0
FISERV INC COM 337738108 14,052 157,938 SH   DFND 1 157,938 0 0
FISKER INC CL A COM STK 33813J106 438 51,089 SH   DFND 1 51,089 0 0
FIVE9 INC COM 338307101 111,077 1,218,748 SH   DFND 1 1,218,748 0 0
FLUENCE ENERGY INC COM CL A 34379V103 109 11,455 SH   DFND 1 11,455 0 0
FLYWIRE CORPORATION COM VTG 302492103 3,455 196,001 SH   DFND 1 196,001 0 0
FORD MTR CO DEL NOTE 3/1 345370CZ1 13,297 14,500,000 SH   DFND 1 14,500,000 0 0
FRESHWORKS INC CLASS A COM 358054104 18,077 1,374,713 SH   DFND 1 1,374,713 0 0
FREYR BATTERY SHS L4135L100 137 20,063 SH   DFND 1 20,063 0 0
FTC SOLAR INC COM 30320C103 955 263,915 SH   DFND 1 263,915 0 0
FUELCELL ENERGY INC COM 35952H601 96 25,695 SH   DFND 1 25,695 0 0
GARMIN LTD SHS H2906T109 772 7,860 SH   DFND 1 7,860 0 0
GENERAC HLDGS INC COM 368736104 665 3,156 SH   DFND 1 3,156 0 0
GENTEX CORP COM 371901109 704 25,170 SH   DFND 1 25,170 0 0
GLOBAL BLOOD THERAPEUTICS IN COM 37890U108 35,011 1,095,810 SH   DFND 1 1,095,810 0 0
GLOBANT S A COM L44385109 14,138 81,253 SH   DFND 1 81,253 0 0
GLOBUS MED INC CL A 379577208 40,047 713,348 SH   DFND 1 713,348 0 0
GOLUB CAP BDC INC COM 38173M102 3,757 289,880 SH   DFND 1 289,880 0 0
GUARDANT HEALTH INC COM 40131M109 1,480 36,690 SH   DFND 1 36,690 0 0
GUARDANT HEALTH INC NOTE 11/1 40131MAB5 18,831 30,250,000 SH   DFND 1 30,250,000 0 0
HAGERTY INC CL A COM 405166109 11,895 1,035,252 SH   DFND 1 1,035,252 0 0
HARMONY BIOSCIENCES HLDGS IN COM 413197104 40,544 831,325 SH   DFND 1 831,325 0 0
HASHICORP INC COM CL A 418100103 7,778 264,195 SH   DFND 1 264,195 0 0
HDFC BANK LTD SPONSORED ADS 40415F101 744 13,532 SH   DFND 1 13,532 0 0
HEALTH CATALYST INC COM 42225T107 386 26,640 SH   DFND 1 26,640 0 0
HEALTHEQUITY INC COM 42226A107 316 5,145 SH   DFND 1 5,145 0 0
HELIOGEN INC COMMON STOCK 42329E105 72 34,297 SH   DFND 1 34,297 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 128,014 1,604,989 SH   DFND 1 1,604,989 0 0
HUAZHU GROUP LTD SPONSORED ADS 44332N106 677 17,762 SH   DFND 1 17,762 0 0
HUAZHU GROUP LTD NOTE 3.000% 5/0 44332NAB2 8,775 7,500,000 SH   DFND 1 7,500,000 0 0
HUBBELL INC COM 443510607 637 3,567 SH   DFND 1 3,567 0 0
HUBSPOT INC COM 443573100 136,984 455,625 SH   DFND 1 455,625 0 0
HUBSPOT INC NOTE 0.375% 6/0 443573AD2 2,581 2,000,000 SH   DFND 1 2,000,000 0 0
HUMANA INC COM 444859102 17,319 37,000 SH   DFND 1 37,000 0 0
HYLIION HOLDINGS CORP COMMON STOCK 449109107 96 29,858 SH   DFND 1 29,858 0 0
HYZON MOTORS INC COM CL A 44951Y102 77 26,153 SH   DFND 1 26,153 0 0
IAC INTERACTIVECORP NEW COM NEW 44891N208 14,540 191,393 SH   DFND 1 191,393 0 0
ICON PLC SHS G4705A100 10,409 48,036 SH   DFND 1 48,036 0 0
IDEANOMICS INC COM 45166V106 57 85,634 SH   DFND 1 85,634 0 0
II-VI INC COM 902104108 361 7,076 SH   DFND 1 7,076 0 0
IMPINJ INC COM 453204109 4,350 74,137 SH   DFND 1 74,137 0 0
INCYTE CORP COM 45337C102 72,251 951,040 SH   DFND 1 951,040 0 0
INDIE SEMICONDUCTOR INC CLASS A COM 45569U101 78 13,737 SH   DFND 1 13,737 0 0
INFINITY PHARMACEUTICALS INC COM 45665G303 3,162 5,000,000 SH   DFND 1 5,000,000 0 0
INNOVIZ TECHNOLOGIES LTD SHS M5R635108 55 14,120 SH   DFND 1 14,120 0 0
INSMED INC COM PAR $.01 457669307 12,460 631,849 SH   DFND 1 631,849 0 0
INTELLIA THERAPEUTICS INC COM 45826J105 13,329 257,510 SH   DFND 1 257,510 0 0
INTERCONTINENTAL EXCHANGE IN COM 45866F104 22,460 238,830 SH   DFND 1 238,830 0 0
INTRA-CELLULAR THERAPIES INC COM 46116X101 50,718 888,537 SH   DFND 1 888,537 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602 19,316 96,239 SH   DFND 1 96,239 0 0
IPG PHOTONICS CORP COM 44980X109 325 3,448 SH   DFND 1 3,448 0 0
IQIYI INC NOTE 2.000% 4/0 46267XAD0 81 100,000 SH   DFND 1 100,000 0 0
IRHYTHM TECHNOLOGIES INC COM 450056106 621 5,750 SH   DFND 1 5,750 0 0
ITRON INC COM 465741106 1,710 34,595 SH   DFND 1 34,595 0 0
IVERIC BIO INC COM 46583P102 17,976 1,868,628 SH   DFND 1 1,868,628 0 0
JAMES RIV GROUP LTD COM G5005R107 22,922 925,000 SH   DFND 1 925,000 0 0
JD.COM INC SPON ADR CL A 47215P106 695 10,815 SH   DFND 1 10,815 0 0
JINKOSOLAR HLDG CO LTD SPONSORED ADR 47759T100 225 3,250 SH   DFND 1 3,250 0 0
JOBY AVIATION INC COMMON STOCK G65163100 313 63,776 SH   DFND 1 63,776 0 0
JOHNSON & JOHNSON COM 478160104 51,580 290,575 SH   DFND 1 290,575 0 0
JOHNSON CTLS INTL PLC SHS G51502105 665 13,880 SH   DFND 1 13,880 0 0
JPMORGAN CHASE & CO COM 46625H100 24,292 215,718 SH   DFND 1 215,718 0 0
KE HLDGS INC SPONSORED ADS 482497104 507 28,221 SH   DFND 1 28,221 0 0
KLA CORP COM NEW 482480100 158,945 498,135 SH   DFND 1 498,135 0 0
KORNIT DIGITAL LTD SHS M6372Q113 36,822 1,161,567 SH   DFND 1 1,161,567 0 0
LABORATORY CORP AMER HLDGS COM NEW 50540R409 4,001 17,072 SH   DFND 1 17,072 0 0
LANTHEUS HLDGS INC COM 516544103 1,453 22,000 SH   DFND 1 22,000 0 0
LATTICE SEMICONDUCTOR CORP COM 518415104 148,187 3,055,399 SH   DFND 1 3,055,399 0 0
LEAR CORP COM NEW 521865204 735 5,835 SH   DFND 1 5,835 0 0
LEGEND BIOTECH CORP SPONSORED ADS 52490G102 31,575 574,087 SH   DFND 1 574,087 0 0
LI AUTO INC SPONSORED ADS 50202M102 1,925 50,249 SH   DFND 1 50,249 0 0
LIBERTY MEDIA CORP DEL COM SER C FRMLA 531229854 10,126 159,533 SH   DFND 1 159,533 0 0
LI-CYCLE HOLDINGS CORP COMMON SHARES 50202P105 198 28,836 SH   DFND 1 28,836 0 0
LILIUM N V CLASS A ORD SHS N52586109 71 30,004 SH   DFND 1 30,004 0 0
LILLY ELI & CO COM 532457108 12,643 38,994 SH   DFND 1 38,994 0 0
LINDE PLC SHS G5494J103 27,320 79,240 SH   DFND 1 79,240 0 0
LITHIUM AMERS CORP NEW COM NEW 53680Q207 501 21,641 SH   DFND 1 21,641 0 0
LITTELFUSE INC COM 537008104 15,048 59,234 SH   DFND 1 59,234 0 0
LIVANOVA PLC SHS G5509L101 42,086 673,704 SH   DFND 1 673,704 0 0
LIVENT CORP COM 53814L108 3,051 134,477 SH   DFND 1 134,477 0 0
LOGITECH INTL S A SHS H50430232 3,269 62,576 SH   DFND 1 62,576 0 0
LORDSTOWN MOTORS CORP COM CL A 54405Q100 53 33,822 SH   DFND 1 33,822 0 0
LPL FINL HLDGS INC COM 50212V100 22,186 120,262 SH   DFND 1 120,262 0 0
LUCID GROUP INC COM 549498103 1,141 66,485 SH   DFND 1 66,485 0 0
LUMENTUM HLDGS INC COM 55024U109 364 4,586 SH   DFND 1 4,586 0 0
LUMINAR TECHNOLOGIES INC COM CL A 550424105 226 38,182 SH   DFND 1 38,182 0 0
LYFT INC CL A COM 55087P104 328 24,714 SH   DFND 1 24,714 0 0
MAGNA INTL INC COM 559222401 834 13,234 SH   DFND 1 13,234 0 0
MARKEL CORP COM 570535104 149,241 115,400 SH   DFND 1 115,400 0 0
MARSH & MCLENNAN COS INC COM 571748102 209,186 1,347,417 SH   DFND 1 1,347,417 0 0
MARVELL TECHNOLOGY INC COM 573874104 128,558 2,953,314 SH   DFND 1 2,953,314 0 0
MASTERCARD INCORPORATED CL A 57636Q104 103,394 327,736 SH   DFND 1 327,736 0 0
MEDTRONIC PLC SHS G5960L103 5,111 56,945 SH   DFND 1 56,945 0 0
MERCADOLIBRE INC COM 58733R102 75,051 117,843 SH   DFND 1 117,843 0 0
MERIDIAN BIOSCIENCE INC COM 589584101 448 14,718 SH   DFND 1 14,718 0 0
MERIT MED SYS INC COM 589889104 30,568 563,251 SH   DFND 1 563,251 0 0
MERUS N V COM N5749R100 11,320 500,000 SH   DFND 1 500,000 0 0
META PLATFORMS INC CL A 30303M102 92,846 575,787 SH   DFND 1 575,787 0 0
MICROCHIP TECHNOLOGY INC. COM 595017104 665 11,442 SH   DFND 1 11,442 0 0
MICRON TECHNOLOGY INC COM 595112103 91,193 1,649,662 SH   DFND 1 1,649,662 0 0
MICROSOFT CORP COM 594918104 876,199 3,411,592 SH   DFND 1 3,411,592 0 0
MICROVAST HOLDINGS INC COM 59516C106 115 51,845 SH   DFND 1 51,845 0 0
MIDDLEBY CORP NOTE 1.000% 9/0 596278AB7 3,404 3,000,000 SH   DFND 1 3,000,000 0 0
MIRATI THERAPEUTICS INC COM 60468T105 1,973 29,390 SH   DFND 1 29,390 0 0
MIRUM PHARMACEUTICALS INC COM 604749101 23,594 1,212,432 SH   DFND 1 1,212,432 0 0
MKS INSTRS INC COM 55306N104 17,062 166,250 SH   DFND 1 166,250 0 0
MODIVCARE INC COM 60783X104 6,079 71,943 SH   DFND 1 71,943 0 0
MOLINA HEALTHCARE INC COM 60855R100 63,769 228,064 SH   DFND 1 228,064 0 0
MONGODB INC CL A 60937P106 83,189 320,576 SH   DFND 1 320,576 0 0
MONOLITHIC PWR SYS INC COM 609839105 114,200 297,364 SH   DFND 1 297,364 0 0
MORGAN STANLEY COM NEW 617446448 8,286 108,942 SH   DFND 1 108,942 0 0
MORPHIC HLDG INC COM 61775R105 7,053 325,000 SH   DFND 1 325,000 0 0
MP MATERIALS CORP COM CL A 553368101 6,091 189,884 SH   DFND 1 189,884 0 0
MSCI INC COM 55354G100 9,786 23,744 SH   DFND 1 23,744 0 0
NANOSTRING TECHNOLOGIES INC COM 63009R109 25,732 2,026,169 SH   DFND 1 2,026,169 0 0
NATERA INC COM 632307104 4,908 138,498 SH   DFND 1 138,498 0 0
NATIONAL INSTRS CORP COM 636518102 272 8,718 SH   DFND 1 8,718 0 0
NAVITAS SEMICONDUCTOR CORP COM 63942X106 389 100,721 SH   DFND 1 100,721 0 0
NETEASE INC SPONSORED ADS 64110W102 427 4,570 SH   DFND 1 4,570 0 0
NETFLIX INC COM 64110L106 11,003 62,923 SH   DFND 1 62,923 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 76,452 784,287 SH   DFND 1 784,287 0 0
NEVRO CORP COM 64157F103 2,895 66,043 SH   DFND 1 66,043 0 0
NEXTNAV INC COMMON STOCK 65345N106 23 10,082 SH   DFND 1 10,082 0 0
NIKOLA CORP COM 654110105 205 42,970 SH   DFND 1 42,970 0 0
NIO INC SPON ADS 62914V106 8,089 372,433 SH   DFND 1 372,433 0 0
NIU TECHNOLOGIES ADS 65481N100 2,977 346,169 SH   DFND 1 346,169 0 0
NORFOLK SOUTHN CORP COM 655844108 13,278 58,417 SH   DFND 1 58,417 0 0
NORTONLIFELOCK INC NOTE 2.000% 8/1 668771AB4 12,627 11,500,000 SH   DFND 1 11,500,000 0 0
NVIDIA CORPORATION COM 67066G104 179,907 1,186,797 SH   DFND 1 1,186,797 0 0
NXP SEMICONDUCTORS N V COM N6596X109 1,461 9,870 SH   DFND 1 9,870 0 0
OKTA INC CL A 679295105 6,370 70,470 SH   DFND 1 70,470 0 0
OMNICELL COM COM 68213N109 1,138 10,007 SH   DFND 1 10,007 0 0
ON SEMICONDUCTOR CORP COM 682189105 106,028 2,107,495 SH   DFND 1 2,107,495 0 0
OPTION CARE HEALTH INC COM NEW 68404L201 48,369 1,740,520 SH   DFND 1 1,740,520 0 0
ORGANON & CO COMMON STOCK 68622V106 711 21,058 SH   DFND 1 21,058 0 0
ORMAT TECHNOLOGIES INC COM 686688102 292 3,726 SH   DFND 1 3,726 0 0
OTONOMO TECHNOLOGIES LTD ORDINARY SHARES M7571L103 15 13,962 SH   DFND 1 13,962 0 0
OUSTER INC COM 68989M103 29 18,122 SH   DFND 1 18,122 0 0
OVINTIV INC COM 69047Q102 16,476 372,854 SH   DFND 1 372,854 0 0
OWENS & MINOR INC NEW COM 690732102 468 14,888 SH   DFND 1 14,888 0 0
PACIRA BIOSCIENCES INC COM 695127100 501 8,595 SH   DFND 1 8,595 0 0
PALO ALTO NETWORKS INC COM 697435105 107,346 217,326 SH   DFND 1 217,326 0 0
PAYCOM SOFTWARE INC COM 70432V102 22,686 80,985 SH   DFND 1 80,985 0 0
PAYPAL HLDGS INC COM 70450Y103 4,700 67,293 SH   DFND 1 67,293 0 0
PENUMBRA INC COM 70975L107 2,092 16,801 SH   DFND 1 16,801 0 0
PHOENIX NEW MEDIA LTD SPONSORED ADS 71910C202 92 18,387 SH   DFND 1 18,387 0 0
PIONEER NAT RES CO NOTE 0.250% 5/1 723787AP2 2,167 1,000,000 SH   DFND 1 1,000,000 0 0
PLUG POWER INC COM NEW 72919P202 2,988 180,331 SH   DFND 1 180,331 0 0
PNC FINL SVCS GROUP INC COM 693475105 15,898 100,766 SH   DFND 1 100,766 0 0
POWER INTEGRATIONS INC COM 739276103 58,549 780,552 SH   DFND 1 780,552 0 0
PRIVIA HEALTH GROUP INC COM 74276R102 423 14,530 SH   DFND 1 14,530 0 0
PROASSURANCE CORP COM 74267C106 46,079 1,950,000 SH   DFND 1 1,950,000 0 0
PROGRESSIVE CORP COM 743315103 76,157 655,000 SH   DFND 1 655,000 0 0
PROGYNY INC COM 74340E103 423 14,558 SH   DFND 1 14,558 0 0
PROTERRA INC COM 74374T109 107 23,055 SH   DFND 1 23,055 0 0
PTC INC COM 69370C100 665 6,250 SH   DFND 1 6,250 0 0
PURE STORAGE INC CL A 74624M102 116,115 4,516,337 SH   DFND 1 4,516,337 0 0
QIAGEN NV SHS NEW N72482123 2,637 46,522 SH   DFND 1 46,522 0 0
QORVO INC COM 74736K101 650 6,893 SH   DFND 1 6,893 0 0
QUALCOMM INC COM 747525103 90,748 710,411 SH   DFND 1 710,411 0 0
QUALTRICS INTL INC COM CL A 747601201 10,046 803,052 SH   DFND 1 803,052 0 0
QUANTA SVCS INC COM 74762E102 665 5,303 SH   DFND 1 5,303 0 0
QUANTUMSCAPE CORP COM CL A 74767V109 629 73,236 SH   DFND 1 73,236 0 0
QUIDELORTHO CORP COM 219798105 435 4,475 SH   DFND 1 4,475 0 0
QUOTIENT LTD SHS G73268107 3,210 13,376,653 SH   DFND 1 13,376,653 0 0
R1 RCM INC COM 77634L105 11,525 549,841 SH   DFND 1 549,841 0 0
RAPID7 INC NOTE 0.250% 3/1 753422AF1 1,812 2,000,000 SH   DFND 1 2,000,000 0 0
REE AUTOMOTIVE LTD CLASS A ORD SHS M8287R103 38 33,092 SH   DFND 1 33,092 0 0
REGAL REXNORD CORPORATION COM 758750103 506 4,454 SH   DFND 1 4,454 0 0
REGENERON PHARMACEUTICALS COM 75886F107 73,891 125,000 SH   DFND 1 125,000 0 0
REINSURANCE GRP OF AMERICA I COM NEW 759351604 87,968 750,000 SH   DFND 1 750,000 0 0
RENAISSANCERE HLDGS LTD COM G7496G103 131,746 842,528 SH   DFND 1 842,528 0 0
REPLIGEN CORP NOTE 0.375% 7/1 759916AB5 4,574 3,000,000 SH   DFND 1 3,000,000 0 0
REVANCE THERAPEUTICS INC COM 761330109 43,078 3,117,052 SH   DFND 1 3,117,052 0 0
RIVIAN AUTOMOTIVE INC COM CL A 76954A103 927 36,004 SH   DFND 1 36,004 0 0
RLI CORP COM 749607107 32,645 280,000 SH   DFND 1 280,000 0 0
ROBLOX CORP CL A 771049103 46,297 1,408,906 SH   DFND 1 1,408,906 0 0
ROCKWELL AUTOMATION INC COM 773903109 4,004 20,088 SH   DFND 1 20,088 0 0
ROMEO POWER INC COM 776153108 6 14,166 SH   DFND 1 14,166 0 0
ROYAL BK CDA COM 780087102 7,466 67,150 SH   DFND 1 67,150 0 0
RYAN SPECIALTY HOLDINGS INC CL A 78351F107 45,069 1,150,000 SH   DFND 1 1,150,000 0 0
S&P GLOBAL INC COM 78409V104 5,797 17,198 SH   DFND 1 17,198 0 0
SABRE CORP COM 78573M104 5,815 997,489 SH   DFND 1 997,489 0 0
SALESFORCE INC COM 79466L302 114,705 695,011 SH   DFND 1 695,011 0 0
SAMSARA INC COM CL A 79589L106 420 37,569 SH   DFND 1 37,569 0 0
SANOFI SPONSORED ADR 80105N105 36,272 725,000 SH   DFND 1 725,000 0 0
SEA LTD SPONSORD ADS 81141R100 20,530 307,066 SH   DFND 1 307,066 0 0
SEAGATE TECHNOLOGY HLDNGS PL ORD SHS G7997R103 35,741 500,293 SH   DFND 1 500,293 0 0
SEAGEN INC COM 81181C104 103,703 586,091 SH   DFND 1 586,091 0 0
SEMTECH CORP COM 816850101 232 4,219 SH   DFND 1 4,219 0 0
SENSATA TECHNOLOGIES HLDG PL SHS G8060N102 1,127 27,293 SH   DFND 1 27,293 0 0
SERVICE CORP INTL COM 817565104 24,221 350,419 SH   DFND 1 350,419 0 0
SERVICENOW INC COM 81762P102 187,102 393,469 SH   DFND 1 393,469 0 0
SES AI CORPORATION CL A COM 78397Q109 79 20,202 SH   DFND 1 20,202 0 0
SHIFT4 PMTS INC NOTE 12/1 82452JAB5 6,654 8,250,000 SH   DFND 1 8,250,000 0 0
SHOALS TECHNOLOGIES GROUP IN CL A 82489W107 183 11,113 SH   DFND 1 11,113 0 0
SHOCKWAVE MED INC COM 82489T104 1,008 5,273 SH   DFND 1 5,273 0 0
SHOPIFY INC CL A 82509L107 27,206 870,860 SH   DFND 1 870,860 0 0
SIGNATURE BK NEW YORK N Y COM 82669G104 14,914 83,221 SH   DFND 1 83,221 0 0
SILICON LABORATORIES INC COM 826919102 341 2,432 SH   DFND 1 2,432 0 0
SILICON LABORATORIES INC NOTE 0.625% 6/1 826919AD4 8,357 6,441,000 SH   DFND 1 6,441,000 0 0
SITIME CORP COM 82982T106 63,010 386,496 SH   DFND 1 386,496 0 0
SKYWORKS SOLUTIONS INC COM 83088M102 665 7,174 SH   DFND 1 7,174 0 0
SLR INVESTMENT CORP COM 83413U100 439 30,000 SH   DFND 1 30,000 0 0
SMARTSHEET INC COM CL A 83200N103 39,495 1,256,595 SH   DFND 1 1,256,595 0 0
SMITH A O CORP COM 831865209 567 10,368 SH   DFND 1 10,368 0 0
SNAP INC CL A 83304A106 41,559 3,165,191 SH   DFND 1 3,165,191 0 0
SNOWFLAKE INC CL A 833445109 84,784 609,691 SH   DFND 1 609,691 0 0
SOCIEDAD QUIMICA Y MINERA DE SPON ADR SER B 833635105 2,460 29,456 SH   DFND 1 29,456 0 0
SOLAREDGE TECHNOLOGIES INC COM 83417M104 80,142 292,830 SH   DFND 1 292,830 0 0
SOLID POWER INC CLASS A COM 83422N105 157 29,265 SH   DFND 1 29,265 0 0
SPIRIT AIRLS INC NOTE 1.000% 5/1 848577AB8 3,626 4,000,000 SH   DFND 1 4,000,000 0 0
SPOTIFY TECHNOLOGY S A SHS L8681T102 9,315 99,271 SH   DFND 1 99,271 0 0
SS&C TECHNOLOGIES HLDGS INC COM 78467J100 23,098 397,760 SH   DFND 1 397,760 0 0
SSR MNG INC NOTE 2.500% 4/0 784730AB9 11,475 10,039,000 SH   DFND 1 10,039,000 0 0
STEM INC COM 85859N102 73 10,250 SH   DFND 1 10,250 0 0
STEREOTAXIS INC COM NEW 85916J409 141 76,687 SH   DFND 1 76,687 0 0
STERIS PLC SHS USD G8473T100 78,203 379,349 SH   DFND 1 379,349 0 0
STRIDE INC NOTE 1.125% 9/0 86333MAA6 2,978 3,000,000 SH   DFND 1 3,000,000 0 0
STRYKER CORPORATION COM 863667101 8,912 44,800 SH   DFND 1 44,800 0 0
SUMMIT THERAPEUTICS INC COM 86627T108 5,599 5,599,407 SH   DFND 1 5,599,407 0 0
SUNPOWER CORP COM 867652406 2,254 142,556 SH   DFND 1 142,556 0 0
SUNRUN INC COM 86771W105 326 13,965 SH   DFND 1 13,965 0 0
SUPERNUS PHARMACEUTICALS INC COM 868459108 22,966 794,120 SH   DFND 1 794,120 0 0
SURGERY PARTNERS INC COM 86881A100 14,335 495,695 SH   DFND 1 495,695 0 0
SVB FINANCIAL GROUP COM 78486Q101 7,136 18,066 SH   DFND 1 18,066 0 0
SYNEOS HEALTH INC CL A 87166B102 5,498 76,696 SH   DFND 1 76,696 0 0
SYNOPSYS INC COM 871607107 83,704 275,613 SH   DFND 1 275,613 0 0
TAKE-TWO INTERACTIVE SOFTWAR COM 874054109 5,055 41,258 SH   DFND 1 41,258 0 0
TANDEM DIABETES CARE INC COM NEW 875372203 1,105 18,673 SH   DFND 1 18,673 0 0
TE CONNECTIVITY LTD SHS H84989104 14,080 124,439 SH   DFND 1 124,439 0 0
TECK RESOURCES LTD CL B 878742204 7,130 233,227 SH   DFND 1 233,227 0 0
TELEFLEX INCORPORATED COM 879369106 3,618 14,718 SH   DFND 1 14,718 0 0
TENABLE HLDGS INC COM 88025T102 66,964 1,474,659 SH   DFND 1 1,474,659 0 0
TENET HEALTHCARE CORP COM NEW 88033G407 21,580 410,570 SH   DFND 1 410,570 0 0
TESLA INC COM 88160R101 80,375 119,354 SH   DFND 1 119,354 0 0
TEXAS INSTRS INC COM 882508104 1,537 10,003 SH   DFND 1 10,003 0 0
THE LION ELECTRIC COMPANY COMMON STOCK 536221104 84 20,010 SH   DFND 1 20,010 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102 12,924 23,788 SH   DFND 1 23,788 0 0
T-MOBILE US INC COM 872590104 40,607 301,824 SH   DFND 1 301,824 0 0
TORONTO DOMINION BK ONT COM NEW 891160509 23,687 314,565 SH   DFND 1 314,565 0 0
TRANE TECHNOLOGIES PLC SHS G8994E103 665 5,117 SH   DFND 1 5,117 0 0
TRAVELERS COMPANIES INC COM 89417E109 108,452 641,233 SH   DFND 1 641,233 0 0
TRIMBLE INC COM 896239100 1,113 19,113 SH   DFND 1 19,113 0 0
TRIPADVISOR INC COM 896945201 66,573 3,740,029 SH   DFND 1 3,740,029 0 0
TRITIUM DCFC LIMITED ORDINARY SHARES Q9225T108 69 11,319 SH   DFND 1 11,319 0 0
TRUPANION INC COM 898202106 42,182 700,000 SH   DFND 1 700,000 0 0
TUSIMPLE HLDGS INC CL A 90089L108 163 22,498 SH   DFND 1 22,498 0 0
TWITTER INC NOTE 3/1 90184LAN2 30,707 34,500,000 SH   DFND 1 34,500,000 0 0
UBER TECHNOLOGIES INC COM 90353T100 8,118 396,785 SH   DFND 1 396,785 0 0
UBS GROUP AG SHS H42097107 11,894 737,849 SH   DFND 1 737,849 0 0
UIPATH INC CL A 90364P105 10,971 603,141 SH   DFND 1 603,141 0 0
UNION PAC CORP COM 907818108 13,721 64,331 SH   DFND 1 64,331 0 0
UNITED RENTALS INC COM 911363109 26,258 108,099 SH   DFND 1 108,099 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102 71,906 305,153 SH   DFND 1 305,153 0 0
UNITEDHEALTH GROUP INC COM 91324P102 85,658 166,770 SH   DFND 1 166,770 0 0
US FOODS HLDG CORP COM 912008109 27,884 908,863 SH   DFND 1 908,863 0 0
VAIL RESORTS INC NOTE 1/0 91879QAN9 33,688 38,500,000 SH   DFND 1 38,500,000 0 0
VALENS SEMICONDUCTOR LTD ORDINARY SHARES M9607U115 36 10,359 SH   DFND 1 10,359 0 0
VEEVA SYS INC CL A COM 922475108 2,300 11,614 SH   DFND 1 11,614 0 0
VELODYNE LIDAR INC COM 92259F101 20 20,747 SH   DFND 1 20,747 0 0
VERTEX ENERGY INC COM 92534K107 4,723 448,975 SH   DFND 1 448,975 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 84,616 300,280 SH   DFND 1 300,280 0 0
VERTICAL AEROSPACE LTD ORD SHS G9471C107 70 22,086 SH   DFND 1 22,086 0 0
VERTIV HOLDINGS CO COM CL A 92537N108 2,499 304,035 SH   DFND 1 304,035 0 0
VISA INC COM CL A 92826C839 131,201 666,365 SH   DFND 1 666,365 0 0
VISTEON CORP COM NEW 92839U206 710 6,857 SH   DFND 1 6,857 0 0
VMWARE INC CL A COM 928563402 665 5,831 SH   DFND 1 5,831 0 0
VOLTA INC COM CL A 92873V102 37 28,299 SH   DFND 1 28,299 0 0
WALLBOX NV SHS CL A N94209108 211 23,734 SH   DFND 1 23,734 0 0
WALMART INC COM 931142103 6,600 54,289 SH   DFND 1 54,289 0 0
WELLS FARGO CO NEW COM 949746101 16,790 428,657 SH   DFND 1 428,657 0 0
WESTERN ALLIANCE BANCORP COM 957638109 7,423 105,137 SH   DFND 1 105,137 0 0
WOLFSPEED INC COM 977852102 1,121 17,665 SH   DFND 1 17,665 0 0
WORKDAY INC CL A 98138H101 32,595 233,522 SH   DFND 1 233,522 0 0
WORKHORSE GROUP INC COM NEW 98138J206 43 16,473 SH   DFND 1 16,473 0 0
XENON PHARMACEUTICALS INC COM 98420N105 77,269 2,540,059 SH   DFND 1 2,540,059 0 0
XL FLEET CORP COM CL A 9837FR100 17 14,724 SH   DFND 1 14,724 0 0
XOS INC COMMON STOCK 98423B108 32 17,204 SH   DFND 1 17,204 0 0
XPENG INC ADS 98422D105 9,948 313,422 SH   DFND 1 313,422 0 0
Y-MABS THERAPEUTICS INC COM 984241109 44,674 2,952,671 SH   DFND 1 2,952,671 0 0
ZAI LAB LTD ADR 98887Q104 4,994 143,997 SH   DFND 1 143,997 0 0
ZENDESK INC COM 98936J101 41,158 555,661 SH   DFND 1 555,661 0 0
ZENTALIS PHARMACEUTICALS INC COM 98943L107 26,699 950,151 SH   DFND 1 950,151 0 0
ZOOM VIDEO COMMUNICATIONS IN CL A 98980L101 57,296 530,666 SH   DFND 1 530,666 0 0