The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Abeona Therapeutics Inc COM 00289Y107 709 2,215,740 SH   SOLE   2,215,740 0 0
Advanced Micro Devices Inc COM 007903107 897 8,200 SH   SOLE   8,200 0 0
Aldeyra Therapeutics Inc COM 01438T106 3,376 759,405 SH   SOLE   759,405 0 0
Altimmune Inc COM NEW 02155H200 810 132,978 SH   SOLE   132,978 0 0
Altria Group Inc COM 02209S103 1,186 22,700 SH   SOLE   22,700 0 0
Angion BioMedica Corp COM 03476J107 127 60,000 SH   SOLE   60,000 0 0
Anavex Life Sciences Corp COM NEW 032797300 2,595 210,789 SH   SOLE   210,789 0 0
Annovis Bio Inc COM 03615A108 190 14,210 SH   SOLE   14,210 0 0
Applied Genetic Technologies COM 03820J100 107 100,000 SH   SOLE   100,000 0 0
Applied Therapeutics Inc COM 03828A101 2,283 1,082,123 SH   SOLE   1,082,123 0 0
Arista Networks Inc COM 040413106 1,918 13,800 SH   SOLE   13,800 0 0
ASML Holdings N Y REGISTRY SHS N07059210 855 1,280 SH   SOLE   1,280 0 0
Biohaven Pharmactl Hldg Co L COM G11196105 106,813 900,844 SH   SOLE   900,844 0 0
Bioxcel Therapeutics Inc COM 09075P105 418 20,000 SH   SOLE   20,000 0 0
Blackstone Group LP COM UNIT LTD 09253U108 2,006 16,000 SH   SOLE   16,000 0 0
Booz Allen Hamilton HLDG COR CL A 099502106 1,142 13,000 SH   SOLE   13,000 0 0
Context Therapeutics Ins COM 21077P108 303 139,520 SH   SOLE   139,520 0 0
Corbus Pharmaceuticals HLDGS COM 21833P103 2,684 5,045,870 SH   SOLE   5,045,870 0 0
Corning Inc COM 219350105 982 26,600 SH   SOLE   26,600 0 0
CVS Health Corp COM 126650100 1,460 14,500 SH   SOLE   14,500 0 0
Eiger Biopharmaceuticals Inc COM 28249U105 5,762 694,232 SH   SOLE   694,232 0 0
Entera Bio Ltd SHS M40527109 7,130 2,484,275 SH   SOLE   2,484,275 0 0
Lumen Technologies Inc COM 156700106 1,127 100,000 SH   SOLE   100,000 0 0
Mirati Therapeutics, Inc COM 60468T105 411 5,000 SH   SOLE   5,000 0 0
Oramed Pharmaceuticals Inc COM NEW 68403P203 173 20,000 SH   SOLE   20,000 0 0
Orgenesis, Inc. COM 68619K105 4,568 1,316,364 SH   SOLE   1,316,364 0 0
Spero Therapeutics Inc COM 84833T103 609 70,000 SH   SOLE   70,000 0 0
Soligenix Inc. COM 834223307 198 271,580 SH   SOLE   271,580 0 0
Thermo Fischer Scientific Inc COM 883556102 1,240 2,100 SH   SOLE   2,100 0 0
Visa COM CL A 92826C839 1,074 4,850 SH   SOLE   4,850 0 0
FRANCO NEV CORP COM 351858105 598 3,750 SH   SOLE   3,750 0 0
MAVERIX METALS INC COM NEW 57776F405 552 115,000 SH   SOLE   115,000 0 0
AGNICO EAGLE MINES LTD COM 008474108 943 15,393 SH   SOLE   15,393 0 0
EQUINOX GOLD CORP COM 29446Y502 376 45,500 SH   SOLE   45,500 0 0
SEABRIDGE GOLD INC COM 811916105 592 32,000 SH   SOLE   32,000 0 0
OSISKO GOLD ROYALTIES LTD COM 68827L101 612 190,000 SH   SOLE   190,000 0 0
MAG SILVER CORP COM 55903Q104 352 21,750 SH   SOLE   17,300 0 0
PAN AMERN SILVER CORP COM 697900108 445 16,300 SH   SOLE   16,300 0 0
SILVERCREST METALS INC COM 828363101 428 48,000 SH   SOLE   48,000 0 0
OSHKOSH CORP COM 688239201 850 8,450 SH   SOLE   8,450 0 0
FIRST MAJESTIC silver corp COM 32076V103 434 33,000 SH   SOLE   33,000 0 0