The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
1LIFE HEALTHCARE INC COM 68269G107 37,726 3,404,835 SH   SOLE   3,404,835 0 0
ABSCI CORPORATION COM 00091E109 67,702 8,031,094 SH   SOLE   8,031,094 0 0
ACHILLES THERAPEUTICS PLC SPONSORED ADS 00449L102 4,728 1,608,089 SH   SOLE   1,608,089 0 0
ADAGIO THERAPEUTICS INC COM 00534A102 8,760 1,920,960 SH   SOLE   1,920,960 0 0
ADC THERAPEUTICS SA SHS H0036K147 109,182 7,432,429 SH   SOLE   7,432,429 0 0
AKERO THERAPEUTICS INC COM 00973Y108 22,736 1,602,285 SH   SOLE   1,602,285 0 0
ALLAKOS INC COM 01671P100 14,592 2,559,975 SH   SOLE   2,559,975 0 0
ALLOVIR INC COM 019818103 5,558 823,371 SH   SOLE   823,371 0 0
ALPHA TEKNOVA INC COM 02080L102 7,841 567,800 SH   SOLE   567,800 0 0
ALX ONCOLOGY HLDGS INC COM 00166B105 13,054 772,397 SH   SOLE   772,397 0 0
AMICUS THERAPEUTICS INC COM 03152W109 211,459 22,329,386 SH   SOLE   22,329,386 0 0
ANNEXON INC COM 03589W102 8,744 3,202,917 SH   SOLE   3,202,917 0 0
ANTHEM INC COM 036752103 40,851 83,162 SH   SOLE   83,162 0 0
ARGENX SE SPONSORED ADR 04016X101 162,682 515,943 SH   SOLE   515,943 0 0
ATARA BIOTHERAPEUTICS INC COM 046513107 58,025 6,245,911 SH   SOLE   6,245,911 0 0
ATRECA INC CL A COM 04965G109 2,537 800,306 SH   SOLE   800,306 0 0
AUGMEDIX INC COM 05105P107 42,278 14,380,327 SH   SOLE   14,380,327 0 0
AYALA PHARMACEUTICALS INC COM 05465V108 1,790 449,731 SH   SOLE   449,731 0 0
BEAM THERAPEUTICS INC COM 07373V105 105,206 1,836,050 SH   SOLE   1,836,050 0 0
BIOVENTUS INC COM CL A 09075A108 18,284 1,296,739 SH   SOLE   1,296,739 0 0
CABALETTA BIO INC COM 12674W109 1,414 696,377 SH   SOLE   696,377 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 69,696 2,046,269 SH   SOLE   2,046,269 0 0
CENTENE CORP DEL COM 15135B101 54,626 648,837 SH   SOLE   648,837 0 0
CYTOSORBENTS CORP COM NEW 23283X206 850 266,365 SH   SOLE   266,365 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 6,163 664,817 SH   SOLE   664,817 0 0
ENTRADA THERAPEUTICS INC COM 29384C108 18,352 1,954,419 SH   SOLE   1,954,419 0 0
EPIZYME INC COM 29428V104 523 454,475 SH   SOLE   454,475 0 0
FATE THERAPEUTICS INC COM 31189P102 502,351 12,957,222 SH   SOLE   12,957,222 0 0
GRITSTONE BIO INC COM 39868T105 28,312 6,871,738 SH   SOLE   6,871,738 0 0
HOOKIPA PHARMA INC COM 43906K100 10,572 4,636,648 SH   SOLE   4,636,648 0 0
ICU MED INC COM 44930G107 21,567 96,869 SH   SOLE   96,869 0 0
IGM BIOSCIENCES INC COM 449585108 89,127 3,334,355 SH   SOLE   3,334,355 0 0
IMMATICS N.V SHS N44445109 5,793 725,000 SH   SOLE   725,000 0 0
IMMUNOGEN INC COM 45253H101 43,877 9,217,945 SH   SOLE   9,217,945 0 0
INVITAE CORP COM 46185L103 30,329 3,805,403 SH   SOLE   3,805,403 0 0
IVERIC BIO INC COM 46583P102 25,006 1,485,800 SH   SOLE   1,485,800 0 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105 17,865 114,764 SH   SOLE   114,764 0 0
KRYSTAL BIOTECH INC COM 501147102 120,817 1,815,698 SH   SOLE   1,815,698 0 0
KYMERA THERAPEUTICS INC COM 501575104 110,668 2,615,030 SH   SOLE   2,615,030 0 0
LAVA THERAPEUTICS NV SHS N51517105 12,391 2,816,196 SH   SOLE   2,816,196 0 0
LIVANOVA PLC SHS G5509L101 161,247 1,970,511 SH   SOLE   1,970,511 0 0
MEDAVAIL HOLDINGS INC COM 58406B103 10,755 11,075,105 SH   SOLE   11,075,105 0 0
NEOLEUKIN THERAPEUTICS INC COM 64049K104 6,515 3,465,435 SH   SOLE   3,465,435 0 0
NEVRO CORP COM 64157F103 29,729 411,017 SH   SOLE   411,017 0 0
NURIX THERAPEUTICS INC COM 67080M103 42,293 3,018,784 SH   SOLE   3,018,784 0 0
NUVATION BIO INC COM CL A 67080N101 18,261 3,471,709 SH   SOLE   3,471,709 0 0
OAK STR HEALTH INC COM 67181A107 32,353 1,203,619 SH   SOLE   1,203,619 0 0
PLIANT THERAPEUTICS INC COM 729139105 21,596 3,080,801 SH   SOLE   3,080,801 0 0
PROTHENA CORP PLC SHS G72800108 26,922 736,175 SH   SOLE   736,175 0 0
RAPT THERAPEUTICS INC COM 75382E109 16,463 748,677 SH   SOLE   748,677 0 0
REGENXBIO INC COM 75901B107 65,614 1,976,923 SH   SOLE   1,976,923 0 0
REPARE THERAPEUTICS INC COM 760273102 38,918 2,732,996 SH   SOLE   2,732,996 0 0
REPLIMUNE GROUP INC COM 76029N106 62,678 3,691,312 SH   SOLE   3,691,312 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103 31,030 2,407,326 SH   SOLE   2,407,326 0 0
SCIENCE 37 HOLDINGS INC COM 808644108 105,974 19,808,234 SH   SOLE   19,808,234 0 0
SEAGEN INC COM 81181C104 63,566 441,274 SH   SOLE   441,274 0 0
SHATTUCK LABS INC COM 82024L103 23,941 5,619,914 SH   SOLE   5,619,914 0 0
SOMALOGIC INC CLASS A COM 83444K105 31,332 3,906,770 SH   SOLE   3,906,770 0 0
SONENDO INC COM 835431107 1,998 498,131 SH   SOLE   498,131 0 0
STEREOTAXIS INC COM NEW 85916J409 5,548 1,487,495 SH   SOLE   1,487,495 0 0
STEVANATO GROUP S P A ORD SHS T9224W109 23,143 1,150,225 SH   SOLE   1,150,225 0 0
STOKE THERAPEUTICS INC COM 86150R107 42,613 2,024,368 SH   SOLE   2,024,368 0 0
TANDEM DIABETES CARE INC COM NEW 875372203 31,540 271,218 SH   SOLE   271,218 0 0
TCR2 THERAPEUTICS INC COM 87808K106 3,021 1,094,645 SH   SOLE   1,094,645 0 0
THE BEAUTY HEALTH COMPANY COM CL A 88331L108 89,540 5,304,505 SH   SOLE   5,304,505 0 0
THE ONCOLOGY INSTITUTE INC COM 68236X100 17,215 2,414,432 SH   SOLE   2,414,432 0 0
UNITEDHEALTH GROUP INC COM 91324P102 27,255 53,445 SH   SOLE   53,445 0 0
VERVE THERAPEUTICS INC COM 92539P101 41,882 1,835,328 SH   SOLE   1,835,328 0 0
XERIS BIOPHARMA HOLDINGS INC COM 98422E103 2,679 1,046,587 SH   SOLE   1,046,587 0 0
ZYMEWORKS INC COM 98985W102 13,848 2,114,197 SH   SOLE   2,114,197 0 0