The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
4D MOLECULAR THERAPEUTICS INC COM 35104E100 4,914 325,000 SH   SOLE   325,000 0 0
908 DEVICES INC COM 65443P102 3,163 166,406 SH   SOLE   166,406 0 0
AVALO THERAPEUTICS INC COM 05338F108 1,054 1,454,400 SH   SOLE   1,454,400 0 0
AVEO PHARMACEUTICALS INC COM NEW 053588307 1,342 240,000 SH   SOLE   240,000 0 0
BICYCLE THERAPEUTICS PLC SPONSORED ADS 088786108 7,679 175,000 SH   SOLE   175,000 0 0
BIOLINERX LTD SPONSORED ADS 09071M205 29 16,667 SH   SOLE   16,667 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 6,659 195,500 SH   SOLE   195,500 0 0
CHIMERIX INC COM 16934W106 27,038 5,903,450 SH   SOLE   5,903,450 0 0
CODEXIS INC COM 192005106 27,734 1,345,000 SH   SOLE   1,345,000 0 0
CRINETICS PHARMACEUTICALS INC COM 22663K107 15,211 693,000 SH   SOLE   693,000 0 0
CYTOKINETICS INC COM NEW 23282W605 14,963 406,500 SH   SOLE   406,500 0 0
EDGEWISE THERAPEUTICS INC COM 28036F105 2,939 303,000 SH   SOLE   303,000 0 0
ETON PHARMACEUTICALS INC COM 29772L108 10,374 2,379,275 SH   SOLE   2,379,275 0 0
FORTRESS BIOTECH INC COM 34960Q109 5,100 3,750,000 SH   SOLE   3,750,000 0 0
FULCRUM THERAPEUTICS INC COM 359616109 3,216 136,000 SH   SOLE   136,000 0 0
GINKGO BIOWORKS HOLDINGS INC CLASS A SHARES 37611X100 3,747 929,780 SH   SOLE   929,780 0 0
GRAPHITE BIO INC COM 38870X104 1,303 255,500 SH   SOLE   255,500 0 0
HARROW HEALTH INC COM 415858109 22,447 3,291,343 SH   SOLE   3,291,343 0 0
HYPERFINE INC COM CL A 44916K106 2,701 763,075 SH   SOLE   763,075 0 0
JOURNEY MEDICINE CORP COM 48115J109 324 67,000 SH   SOLE   67,000 0 0
KEROS THERAPEUTICS INC COM 492327101 14,451 265,750 SH   SOLE   265,750 0 0
KINIKSA PHARMACEUTICALS LTD COM CL A G5269C101 11,058 1,112,500 SH   SOLE   1,112,500 0 0
LARIMAR THERAPEUTICS INC COM 517125100 3,822 943,702 SH   SOLE   943,702 0 0
LIQUIDIA CORPORATION COM NEW 53635D202 1,284 178,800 SH   SOLE   178,800 0 0
MACROGENICS INC COM 556099109 3,316 376,400 SH   SOLE   376,400 0 0
MERSANA THERAPEUTICS INC COM 59045L106 2,833 710,000 SH   SOLE   710,000 0 0
MERUS N.V. COM N5749R100 8,937 338,000 SH   SOLE   338,000 0 0
MODULAR MEDICAL INC COM NEW 60785L207 1,171 266,100 SH   SOLE   266,100 0 0
NEOLEUKIN THERAPEUTICS INC COM 64049K104 1,485 790,000 SH   SOLE   790,000 0 0
NUCANA PLC SPONSORED ADR 67022C106 878 878,700 SH   SOLE   878,700 0 0
OCULAR THERAPEUTIX INC COM 67576A100 29,575 5,974,800 SH   SOLE   5,974,800 0 0
PROQR THERAPEUTICS NV SHS EURO N71542109 2,195 2,425,000 SH   SOLE   2,425,000 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102 5,956 251,500 SH   SOLE   251,500 0 0
PROTARA THERAPEUTICS INC COM STK 74365U107 13,664 2,674,031 SH   SOLE   2,674,031 0 0
REATA PHARMACEUTICALS INC CLASS A 75615P103 13,333 407,002 SH   SOLE   407,002 0 0
REPARE THERAPEUTICS INC COM 760273102 793 55,678 SH   SOLE   55,678 0 0
SEMLER SCIENTIFIC INC COM 81684M104 3,469 70,000 SH   SOLE   70,000 0 0
STEREOTAXIS INC COM NEW 85916J409 8,936 2,395,600 SH   SOLE   2,395,600 0 0
SUTRO BIOPHARMA INC COM 869367102 740 89,980 SH   SOLE   89,980 0 0
SYNLOGIC INC COM 87166L100 2,362 984,200 SH   SOLE   984,200 0 0
TELA BIO INC COM 872381108 5,548 477,000 SH   SOLE   477,000 0 0
TRACON PHARMACEUTICALS INC COM NEW 89237H209 8,298 3,155,098 SH   SOLE   3,155,098 0 0
VAXCYTE INC COM 92243G108 5,096 211,000 SH   SOLE   211,000 0 0
VERASTEM INC COM 92337C104 3,278 2,325,000 SH   SOLE   2,325,000 0 0
XOMA CORP DEL COM NEW 98419J206 7,583 271,000 SH   SOLE   271,000 0 0