The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| 2SEVENTY BIO INC | COMMON STOCK | 901384107 | 13,984 | 819,672 | SH | DFND | 819,672 | 0 | 0 | ||
| AKOUOS INC | COM | 00973J101 | 3,972 | 836,120 | SH | DFND | 836,120 | 0 | 0 | ||
| COMPASS THERAPEUTICS INC | COM | 20454B104 | 3,877 | 2,829,712 | SH | DFND | 2,829,712 | 0 | 0 | ||
| CORVUS PHARMACEUTICALS INC | COM | 221015100 | 2,793 | 1,703,137 | SH | DFND | 1,703,137 | 0 | 0 | ||
| CULLINAN ONCOLOGY INC | COM | 230031106 | 28,824 | 2,753,047 | SH | DFND | 2,753,047 | 0 | 0 | ||
| FREELINE THERAPEUTICS HLDGS | SPONSORED ADS | 35655L107 | 5,446 | 4,862,319 | SH | DFND | 4,862,319 | 0 | 0 | ||
| G1 THERAPEUTICS INC | COM | 3621LQ109 | 3,714 | 488,635 | SH | DFND | 488,635 | 0 | 0 | ||
| IKENA ONCOLOGY INC | COM | 45175G108 | 4,970 | 814,755 | SH | DFND | 814,755 | 0 | 0 | ||
| INOZYME PHARMA INC | COM | 45790W108 | 3,649 | 892,057 | SH | DFND | 892,057 | 0 | 0 | ||
| KEROS THERAPEUTICS INC | COM | 492327101 | 3,384 | 62,229 | SH | DFND | 62,229 | 0 | 0 | ||
| KEZAR LIFE SCIENCES INC | COM | 49372L100 | 5,229 | 314,612 | SH | DFND | 314,612 | 0 | 0 | ||
| LARIMAR THERAPEUTICS INC | COM | 517125100 | 6,136 | 1,515,148 | SH | DFND | 1,515,148 | 0 | 0 | ||
| OMEGA THERAPEUTICS INC | COMMON STOCK | 68217N105 | 6,589 | 1,055,882 | SH | DFND | 1,055,882 | 0 | 0 | ||
| ONCORUS INC | COM | 68236R103 | 4,303 | 2,417,436 | SH | DFND | 2,417,436 | 0 | 0 | ||
| ORCHARD THERAPEUTICS PLC | ADS | 68570P101 | 3,779 | 5,307,751 | SH | DFND | 5,307,751 | 0 | 0 | ||
| OVID THERAPEUTICS INC | COM | 690469101 | 2,678 | 852,888 | SH | DFND | 852,888 | 0 | 0 | ||
| PLIANT THERAPEUTICS INC | COM | 729139105 | 18,629 | 2,657,457 | SH | DFND | 2,657,457 | 0 | 0 | ||
| PRECISION BIOSCIENCES INC | COM | 74019P108 | 1,868 | 606,629 | SH | DFND | 606,629 | 0 | 0 | ||
| PROMETHEUS BIOSCIENCES INC | COM | 74349U108 | 59,853 | 1,585,096 | SH | DFND | 1,585,096 | 0 | 0 | ||
| REPARE THERAPEUTICS INC | COM | 760273102 | 36,755 | 2,581,097 | SH | DFND | 2,581,097 | 0 | 0 | ||
| SPDR SER TR | S&P BIOTECH | 78464A870 | 206 | 222,500 | SH | Put | DFND | 222,500 | 0 | 0 | |
| VECTIVBIO HLDG AG | ORD SHS | H9060V101 | 14,527 | 3,084,310 | SH | DFND | 3,084,310 | 0 | 0 | ||