The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Axcella Health Inc COM 05454B105 32,487 12,640,890 SH   DFND 2,3 0 12,640,890 0
Axcella Health Inc COM 05454B105 11,477 4,465,866 SH   DFND 3,4 0 4,465,866 0
Axcella Health Inc COM 05454B105 4,526 1,761,029 SH   DFND 3 0 1,761,029 0
Codiak Biosciences Inc COM 192010106 13,301 2,121,354 SH   DFND 1,3 0 2,121,354 0
Codiak Biosciences Inc COM 192010106 3,047 485,949 SH   DFND 3 0 485,949 0
Denali Therapeutics Inc COM 24823R105 84,284 2,619,968 SH   DFND 1,3 0 2,619,968 0
Evelo Biosciences Inc COM 299734103 34,596 10,205,282 SH   DFND 1,3 0 10,205,282 0
Evelo Biosciences Inc COM 299734103 15,876 4,683,213 SH   DFND 2,3 0 4,683,213 0
Evelo Biosciences Inc COM 299734103 13,985 4,125,461 SH   DFND 3,4 0 4,125,461 0
Evelo Biosciences Inc COM 299734103 4,646 1,370,476 SH   DFND 3,6 0 1,370,476 0
Evelo Biosciences Inc COM 299734103 8,969 2,645,637 SH   DFND 3 0 2,645,637 0
Foghorn Therapeutics Inc COM 344174107 142,109 9,330,878 SH   DFND 1,3 0 9,330,878 0
Foghorn Therapeutics Inc COM 344174107 22,715 1,491,441 SH   DFND 3,4 0 1,491,441 0
Foghorn Therapeutics Inc COM 344174107 28,203 1,851,801 SH   DFND 3,5 0 1,851,801 0
Kaleido Biosciences Inc COM 483347100 16,104 9,759,979 SH   DFND 1,3 0 9,759,979 0
Kaleido Biosciences Inc COM 483347100 2,852 1,728,309 SH   DFND 2,3 0 1,728,309 0
Kaleido Biosciences Inc COM 483347100 4,921 2,982,639 SH   DFND 3,4 0 2,982,639 0
Kaleido Biosciences Inc COM 483347100 1,218 738,333 SH   DFND 3,6 0 738,333 0
Kaleido Biosciences Inc COM 483347100 7,205 4,366,450 SH   DFND 3 0 4,366,450 0
Moderna Inc COM 60770K107 3,027,830 17,577,092 SH   DFND 2,3 0 17,577,092 0
Moderna Inc COM 60770K107 676 3,924 SH   DFND 3 0 3,924 0
Omega Therapeutics Inc COM 68217N105 43,586 6,984,856 SH   DFND 1,3 0 6,984,856 0
Omega Therapeutics Inc COM 68217N105 34,412 5,514,707 SH   DFND 3,5 0 5,514,707 0
Omega Therapeutics Inc COM 68217N105 6,056 970,588 SH   DFND 3,6 0 970,588 0
Omega Therapeutics Inc COM 68217N105 53,773 8,617,413 SH   DFND 3,7 0 8,617,413 0
Omega Therapeutics Inc COM 68217N105 23,804 3,814,705 SH   DFND 3 0 3,814,705 0
Rubius Therapeutics Inc COM 78116T103 64,185 11,648,828 SH   DFND 1,3 0 11,648,828 0
Rubius Therapeutics Inc COM 78116T103 133,474 24,223,995 SH   DFND 2,3 0 24,223,995 0
Rubius Therapeutics Inc COM 78116T103 14,512 2,633,703 SH   DFND 3,4 0 2,633,703 0
Sana Biotechnology Inc COM 799566104 107,979 13,072,570 SH   DFND 1,3 0 13,072,570 0
Sana Biotechnology Inc COM 799566104 80,330 9,725,122 SH   DFND 3,7 0 9,725,122 0
Sana Biotechnology Inc COM 799566104 94,505 11,441,326 SH   DFND 3 0 11,441,326 0
Seres Therapeutics Inc COM 81750R102 60,184 8,452,876 SH   DFND 2,3 0 8,452,876 0
Seres Therapeutics Inc COM 81750R102 21,096 2,962,963 SH   DFND 3,7 0 2,962,963 0
Seres Therapeutics Inc COM 81750R102 21,096 2,962,963 SH   DFND 3,6 0 2,962,963 0
Sigilon Therapeutics Inc COM 82657L107 13,067 8,888,888 SH   DFND 1,3 0 8,888,888 0
Sigilon Therapeutics Inc COM 82657L107 2,178 1,481,481 SH   DFND 3,5 0 1,481,481 0
Syros Pharmaceuticals Inc COM 87184Q107 3,497 2,938,494 SH   DFND 2,3 0 2,938,494 0