The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| 4D MOLECULAR THERAPEUTICS IN | COM | 35104E100 | 37,017 | 2,448,200 | SH | SOLE | 2,448,200 | 0 | 0 | ||
| ACUMEN PHARMACEUTICALS INC | COM | 00509G209 | 10,162 | 2,599,098 | SH | SOLE | 2,599,098 | 0 | 0 | ||
| AGENUS INC | COM NEW | 00847G705 | 34,436 | 13,998,491 | SH | SOLE | 13,998,491 | 0 | 0 | ||
| ALNYLAM PHARMACEUTICALS INC | COM | 02043Q107 | 75,712 | 463,663 | SH | SOLE | 463,663 | 0 | 0 | ||
| ANAPTYSBIO INC | COM | 032724106 | 13,824 | 558,782 | SH | SOLE | 558,782 | 0 | 0 | ||
| ASSEMBLY BIOSCIENCES INC | COM | 045396108 | 6,180 | 3,000,000 | SH | SOLE | 3,000,000 | 0 | 0 | ||
| ATYR PHARMA INC | COM NEW | 002120202 | 5,503 | 1,028,515 | SH | SOLE | 1,028,515 | 0 | 0 | ||
| AUTOLUS THERAPEUTICS PLC | SPON ADS | 05280R100 | 1,595 | 382,559 | SH | SOLE | 382,559 | 0 | 0 | ||
| BEAM THERAPEUTICS INC | COM | 07373V105 | 43,763 | 763,750 | SH | SOLE | 763,750 | 0 | 0 | ||
| BICYCLE THERAPEUTICS PLC | SPONSORED ADS | 088786108 | 81,441 | 1,855,993 | SH | SOLE | 1,855,993 | 0 | 0 | ||
| CENTURY THERAPEUTICS INC | COM | 15673T100 | 11,664 | 926,469 | SH | SOLE | 926,469 | 0 | 0 | ||
| CHINOOK THERAPEUTICS INC | COM | 16961L106 | 49,080 | 3,000,000 | SH | SOLE | 3,000,000 | 0 | 0 | ||
| CRINETICS PHARMACEUTICALS IN | COM | 22663K107 | 33,841 | 1,541,715 | SH | SOLE | 1,541,715 | 0 | 0 | ||
| DICE THERAPEUTICS INC | COM | 23345J104 | 23,913 | 1,250,000 | SH | SOLE | 1,250,000 | 0 | 0 | ||
| DYNE THERAPEUTICS INC | COM | 26818M108 | 33,740 | 3,500,000 | SH | SOLE | 3,500,000 | 0 | 0 | ||
| ENANTA PHARMACEUTICALS INC | COM | 29251M106 | 14,146 | 198,730 | SH | SOLE | 198,730 | 0 | 0 | ||
| ESPERION THERAPEUTICS INC NE | COM | 29664W105 | 27,840 | 6,000,000 | SH | SOLE | 6,000,000 | 0 | 0 | ||
| FATE THERAPEUTICS INC | COM | 31189P102 | 77,540 | 2,000,000 | SH | SOLE | 2,000,000 | 0 | 0 | ||
| FORMA THERAPEUTICS HLDGS INC | SHS | 34633R104 | 15,435 | 1,659,706 | SH | SOLE | 1,659,706 | 0 | 0 | ||
| FULCRUM THERAPEUTICS INC | COM | 359616109 | 15,373 | 650,000 | SH | SOLE | 650,000 | 0 | 0 | ||
| GH RESEARCH PLC | ORDINARY SHARES | G3855L106 | 9,134 | 499,400 | SH | SOLE | 499,400 | 0 | 0 | ||
| GLOBAL BLOOD THERAPEUTICS IN | COM | 37890U108 | 79,834 | 2,304,683 | SH | SOLE | 2,304,683 | 0 | 0 | ||
| GRITSTONE BIO INC | COM | 39868T105 | 12,301 | 2,985,729 | SH | SOLE | 2,985,729 | 0 | 0 | ||
| HOOKIPA PHARMA INC | COM | 43906K100 | 11,482 | 5,035,998 | SH | SOLE | 5,035,998 | 0 | 0 | ||
| IMMUNOVANT INC | COM | 45258J102 | 39,808 | 7,224,613 | SH | SOLE | 7,224,613 | 0 | 0 | ||
| IVERIC BIO INC | COM | 46583P102 | 75,735 | 4,500,000 | SH | SOLE | 4,500,000 | 0 | 0 | ||
| JAZZ PHARMACEUTICALS PLC | SHS USD | G50871105 | 80,489 | 517,051 | SH | SOLE | 517,051 | 0 | 0 | ||
| JOUNCE THERAPEUTICS INC | COM | 481116101 | 28,923 | 4,259,653 | SH | SOLE | 4,259,653 | 0 | 0 | ||
| KALVISTA PHARMACEUTICALS INC | COM | 483497103 | 25,497 | 1,729,757 | SH | SOLE | 1,729,757 | 0 | 0 | ||
| KEROS THERAPEUTICS INC | COM | 492327101 | 75,061 | 1,380,306 | SH | SOLE | 1,380,306 | 0 | 0 | ||
| KURA ONCOLOGY INC | COM | 50127T109 | 54,865 | 3,412,000 | SH | SOLE | 3,412,000 | 0 | 0 | ||
| MADRIGAL PHARMACEUTICALS INC | COM | 558868105 | 77,122 | 786,000 | SH | SOLE | 786,000 | 0 | 0 | ||
| MAGENTA THERAPEUTICS INC | COM | 55910K108 | 15,541 | 5,359,000 | SH | SOLE | 5,359,000 | 0 | 0 | ||
| NEKTAR THERAPEUTICS | COM | 640268108 | 2,695 | 500,000 | SH | Put | SOLE | 500,000 | 0 | 0 | |
| NEKTAR THERAPEUTICS | COM | 640268108 | 5,390 | 1,000,000 | SH | Call | SOLE | 1,000,000 | 0 | 0 | |
| NKARTA INC | COM | 65487U108 | 24,055 | 2,113,795 | SH | SOLE | 2,113,795 | 0 | 0 | ||
| NOVOCURE LTD | ORD SHS | G6674U108 | 82,850 | 1,000,000 | SH | SOLE | 1,000,000 | 0 | 0 | ||
| NUVATION BIO INC | COM CL A | 67080N101 | 6,078 | 1,155,492 | SH | SOLE | 1,155,492 | 0 | 0 | ||
| PASSAGE BIO INC | COM | 702712100 | 10,463 | 3,375,000 | SH | SOLE | 3,375,000 | 0 | 0 | ||
| PROMETHEUS BIOSCIENCES INC | COM | 74349U108 | 9,251 | 245,000 | SH | SOLE | 245,000 | 0 | 0 | ||
| PROTAGONIST THERAPEUTICS INC | COM | 74366E102 | 3,512 | 148,300 | SH | Put | SOLE | 148,300 | 0 | 0 | |
| RAFAEL HLDGS INC | COM CL B | 75062E106 | 261 | 104,156 | SH | SOLE | 104,156 | 0 | 0 | ||
| RELMADA THERAPEUTICS INC | COM | 75955J402 | 2,756 | 102,117 | SH | SOLE | 102,117 | 0 | 0 | ||
| REPARE THERAPEUTICS INC | COM | 760273102 | 37,936 | 2,664,017 | SH | SOLE | 2,664,017 | 0 | 0 | ||
| SAGE THERAPEUTICS INC | COM | 78667J108 | 22,343 | 675,000 | SH | SOLE | 675,000 | 0 | 0 | ||
| SILENCE THERAPEUTICS PLC | ADS | 82686Q101 | 18,080 | 951,580 | SH | SOLE | 951,580 | 0 | 0 | ||
| TENAYA THERAPEUTICS INC | COM | 87990A106 | 6,443 | 546,923 | SH | SOLE | 546,923 | 0 | 0 | ||
| TRAVERE THERAPEUTICS INC | COM | 89422G107 | 80,776 | 3,134,503 | SH | SOLE | 3,134,503 | 0 | 0 | ||
| TRICIDA INC | COM | 89610F101 | 21,805 | 2,652,693 | SH | SOLE | 2,652,693 | 0 | 0 | ||
| VERVE THERAPEUTICS INC | COM | 92539P101 | 2,335 | 102,342 | SH | SOLE | 102,342 | 0 | 0 | ||
| VIGIL NEUROSCIENCE INC | COM | 92673K108 | 2,736 | 389,141 | SH | SOLE | 389,141 | 0 | 0 | ||
| VIRIDIAN THERAPEUTICS INC | COM | 92790C104 | 21,639 | 1,170,290 | SH | SOLE | 1,170,290 | 0 | 0 | ||