The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Abeona Therapeutics Inc COM 00289Y107 651 2,215,740 SH   SOLE   2,215,740 0 0
Advanced Micro Deviced Inc COM 007903107 1,777 12,350 SH   SOLE   12,350 0 0
Aldeyra Therapeutics Inc COM 01438T106 3,038 759,405 SH   SOLE   759,405 0 0
Altimmune Inc COM NEW 02155H200 1,218 132,978 SH   SOLE   132,978 0 0
Altria Group Inc COM 02209S103 1,064 22,700 SH   SOLE   22,700 0 0
Angion BioMedica Corp COM 03476J107 174 60,000 SH   SOLE   60,000 0 0
Anavex Life Sciemves Corp COM NEW 003279730 3,655 210,789 SH   SOLE   210,789 0 0
Annovis COM 03615A108 250 14,210 SH   SOLE   14,210 0 0
Applied genetic therapies COM 03820J100 190 100,000 SH   SOLE   100,000 0 0
Applied Therapeutics Inc COM 03828A101 9,238 1,032,123 SH   SOLE   1,032,123 0 0
Arista Networks Inc COM 040413106 1,926 13,800 SH   SOLE   13,800 0 0
ASML Holdings N Y REGISTRY SHS N07059210 1,014 1,280 SH   SOLE   1,280 0 0
Biohaven Pharmactl Hldg Co L COM G11196105 123,594 896,844 SH   SOLE   896,844 0 0
BioXCel Therapeutics Inc COM 09075P105 407 20,000 SH   SOLE   20,000 0 0
Blackstone Group LP COM UNIT LTD 09253U108 3,105 24,000 SH   SOLE   24,000 0 0
Booz Allen Hamilton HLDG COR CL A 099502106 1,071 13,000 SH   SOLE   13,000 0 0
Corbus Pharmaceuticals HLDGS COM 21833P103 3,107 5,045,870 SH   SOLE   5,045,870 0 0
Corning Inc COM 219350105 968 26,600 SH   SOLE   26,600 0 0
CVS Health Corp COM 126650100 1,463 14,500 SH   SOLE   14,500 0 0
Eiger Biopharmaceuticals Inc COM 28249U105 3,603 694,232 SH   SOLE   694,232 0 0
Entera Bio Ltd SHS M40527109 6,993 2,484,275 SH   SOLE   2,484,275 0 0
Lumen Technologies Inc COM 156700106 1,255 100,000 SH   SOLE   100,000 0 0
Orgenesis, Inc. COM 68619K105 3,791 1,316,364 SH   SOLE   1,316,364 0 0
Soligenix Inc. COM 834223307 288 436,580 SH   SOLE   436,580 0 0
Thermo Fischer Scientific Inc COM 883556102 1,401 2,100 SH   SOLE   2,100 0 0
Visa COM CL A 92826C839 1,051 4,850 SH   SOLE   4,850 0 0
FRANCO NEV CORP COM 351858105 519 3,750 SH   SOLE   3,750 0 0
MAVERIX METALS INC COM NEW 57776F405 501 115,000 SH   SOLE   115,000 0 0
AGNICO EAGLE MINES LTD COM 008474108 367 6,900 SH   SOLE   6,900 0 0
KIRKLAND LAKE GOLD LTD COM 49741E100 451 10,750 SH   SOLE   10,750 0 0
EQUINOX GOLD CORP COM 29446Y502 308 45,500 SH   SOLE   45,500 0 0
SEABRIDGE GOLD INC COM 811916105 528 32,000 SH   SOLE   32,000 0 0
OSISKO GOLD ROYALTIES LTD COM 68827L101 579 190,000 SH   SOLE   190,000 0 0
MAG SILVER CORP COM 55903Q104 341 17,300 SH   SOLE   17,300 0 0
PAN AMERN SILVER CORP COM 697900108 407 8,200 SH   SOLE   8,200 0 0
SILVERCREST METALS INC COM 828363101 381 42,000 SH   SOLE   42,000 0 0
OSHKOSH CORP COM 688239201 925 8,450 SH   SOLE   8,450 0 0
FIRST MAJESTIC silver corp COM 32076V103 376 33,000 SH   SOLE   33,000 0 0