The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
10X GENOMICS INC CL A COM 88025U109 16,097 108,063 SH   DFND 1 108,063 0 0
2U INC COM 90214J101 2,341 116,653 SH   DFND 1 116,653 0 0
2U INC NOTE 2.250% 5/0 90214JAB7 1,222 1,150,000 SH   DFND 1 1,150,000 0 0
51JOB INC SPONSORED ADS 316827104 715 14,622 SH   DFND 1 14,622 0 0
ABBOTT LABS COM 002824100 26,169 185,937 SH   DFND 1 185,937 0 0
ABBVIE INC COM 00287Y109 6,279 46,376 SH   DFND 1 46,376 0 0
ACADIA HEALTHCARE COMPANY IN COM 00404A109 75,676 1,246,729 SH   DFND 1 1,246,729 0 0
ACUITY BRANDS INC COM 00508Y102 580 2,740 SH   DFND 1 2,740 0 0
ADDUS HOMECARE CORP COM 006739106 40,497 433,077 SH   DFND 1 433,077 0 0
ADICET BIO INC COM 007002108 26,712 1,527,273 SH   DFND 1 1,527,273 0 0
ADOBE SYSTEMS INCORPORATED COM 00724F101 191,500 337,706 SH   DFND 1 337,706 0 0
ADVANCED ENERGY INDS COM 007973100 269 2,950 SH   DFND 1 2,950 0 0
ADVANCED MICRO DEVICES INC COM 007903107 479,041 3,328,986 SH   DFND 1 3,328,986 0 0
AEVA TECHNOLOGIES INC COM 00835Q103 171 22,601 SH   DFND 1 22,601 0 0
AEYE INC CL A COM 008183105 79 16,327 SH   DFND 1 16,327 0 0
AFFILIATED MANAGERS GROUP IN COM 008252108 23,527 143,012 SH   DFND 1 143,012 0 0
AFLAC INC COM 001055102 24,962 427,500 SH   DFND 1 427,500 0 0
AIR PRODS & CHEMS INC COM 009158106 1,839 6,045 SH   DFND 1 6,045 0 0
AIR TRANS SVCS GROUP INC NOTE 1.125%10/1 00922RAB1 21,920 19,615,000 SH   DFND 1 19,615,000 0 0
AIRBNB INC COM CL A 009066101 163,057 979,381 SH   DFND 1 979,381 0 0
AKAMAI TECHNOLOGIES INC NOTE 0.375% 9/0 00971TAL5 17,616 15,000,000 SH   DFND 1 15,000,000 0 0
AKOYA BIOSCIENCES INC COM 00974H104 20,140 1,315,470 SH   DFND 1 1,315,470 0 0
ALARM COM HLDGS INC COM 011642105 332 3,920 SH   DFND 1 3,920 0 0
ALBEMARLE CORP COM 012653101 2,926 12,518 SH   DFND 1 12,518 0 0
ALCON AG ORD SHS H01301128 78,774 931,494 SH   DFND 1,2 931,494 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 1,199 10,093 SH   DFND 1 10,093 0 0
ALIGN TECHNOLOGY INC COM 016255101 18,007 27,400 SH   DFND 1 27,400 0 0
ALLEGHANY CORP MD COM 017175100 109,017 163,300 SH   DFND 1 163,300 0 0
ALLEGRO MICROSYSTEMS INC COM 01749D105 725 20,033 SH   DFND 1 20,033 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 90,832 535,631 SH   DFND 1 535,631 0 0
ALPHABET INC CAP STK CL A 02079K305 610,766 210,824 SH   DFND 1 210,824 0 0
ALPHABET INC CAP STK CL A 02079K305 456,284 157,500 SH Call DFND 1 157,500 0 0
ALPHABET INC CAP STK CL C 02079K107 659,134 227,791 SH   DFND 1,2 227,791 0 0
ALTAIR ENGR INC COM CL A 021369103 644 8,326 SH   DFND 1 8,326 0 0
AMAZON COM INC COM 023135106 409,657 122,860 SH   DFND 1 122,860 0 0
AMBARELLA INC SHS G037AX101 92,622 456,514 SH   DFND 1 456,514 0 0
AMEDISYS INC COM 023436108 16,330 100,880 SH   DFND 1 100,880 0 0
AMERESCO INC CL A 02361E108 329 4,037 SH   DFND 1 4,037 0 0
AMERISOURCEBERGEN CORP COM 03073E105 15,486 116,532 SH   DFND 1 116,532 0 0
AMETEK INC COM 031100100 21,505 146,250 SH   DFND 1 146,250 0 0
AMGEN INC COM 031162100 6,460 28,717 SH   DFND 1 28,717 0 0
ANALOG DEVICES INC COM 032654105 38,496 219,011 SH   DFND 1 219,011 0 0
ANGIODYNAMICS INC COM 03475V101 42,686 1,547,726 SH   DFND 1 1,547,726 0 0
ANSYS INC COM 03662Q105 6,006 14,972 SH   DFND 1 14,972 0 0
ANTHEM INC COM 036752103 37,435 80,760 SH   DFND 1 80,760 0 0
AON PLC SHS CL A G0403H108 101,439 337,500 SH   DFND 1 337,500 0 0
APPLE INC COM 037833100 894,400 5,036,885 SH   DFND 1 5,036,885 0 0
APPLE INC COM 037833100 852,336 4,800,000 SH Call DFND 1 4,800,000 0 0
APPLIED MATLS INC COM 038222105 203,966 1,296,174 SH   DFND 1 1,296,174 0 0
APTARGROUP INC COM 038336103 62,658 511,577 SH   DFND 1 511,577 0 0
APTIV PLC SHS G6095L109 99,412 602,682 SH   DFND 1 602,682 0 0
ARCH CAP GROUP LTD ORD G0450A105 245,515 5,523,395 SH   DFND 1 5,523,395 0 0
ARCHER AVIATION INC COM CL A 03945R102 151 25,064 SH   DFND 1 25,064 0 0
ARCO PLATFORM LTD COM CL A G04553106 9,455 452,594 SH   DFND 1 452,594 0 0
ARCUTIS BIOTHERAPEUTICS INC COM 03969K108 37,000 1,784,005 SH   DFND 1 1,784,005 0 0
ARENA PHARMACEUTICALS INC COM NEW 040047607 4,176 44,930 SH   DFND 1 44,930 0 0
ARES CAPITAL CORP COM 04010L103 5,424 255,972 SH   DFND 1 255,972 0 0
ARISTA NETWORKS INC COM 040413106 258,603 1,798,978 SH   DFND 1 1,798,978 0 0
ARRAY TECHNOLOGIES INC COM SHS 04271T100 166 10,573 SH   DFND 1 10,573 0 0
ARRIVAL GROUP SHS L0423Q108 495 66,714 SH   DFND 1 66,714 0 0
ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,139 17,182 SH   DFND 1 17,182 0 0
ATLASSIAN CORP PLC CL A G06242104 6,589 17,280 SH   DFND 1 17,280 0 0
ATRICURE INC COM 04963C209 36,625 526,758 SH   DFND 1 526,758 0 0
AUTODESK INC COM 052769106 783 2,785 SH   DFND 1 2,785 0 0
AVADEL PHARMACEUTICALS PLC SPONSORED ADR 05337M104 22,581 2,794,673 SH   DFND 1 2,794,673 0 0
AVANTOR INC COM 05352A100 75,747 1,797,503 SH   DFND 1 1,797,503 0 0
AXON ENTERPRISE INC COM 05464C101 30,826 196,342 SH   DFND 1 196,342 0 0
AXONICS INC COM 05465P101 40,853 729,518 SH   DFND 1 729,518 0 0
BALLARD PWR SYS INC NEW COM 058586108 776 54,746 SH   DFND 1 54,746 0 0
BANDWIDTH INC NOTE 0.250% 3/0 05988JAB9 1,063 1,000,000 SH   DFND 1 1,000,000 0 0
BANK OF NT BUTTERFIELD&SON L SHS NEW G0772R208 7,815 205,061 SH   DFND 1 205,061 0 0
BAXTER INTL INC COM 071813109 21,631 251,993 SH   DFND 1 251,993 0 0
BELLUS HEALTH INC NEW COM NEW 07987C204 16,100 2,000,000 SH   DFND 1 2,000,000 0 0
BERKLEY W R CORP COM 084423102 97,941 1,188,750 SH   DFND 1 1,188,750 0 0
BERKSHIRE HATHAWAY INC DEL CL B NEW 084670702 79,992 267,531 SH   DFND 1 267,531 0 0
BILIBILI INC SPONS ADS REP Z 090040106 262 5,646 SH   DFND 1 5,646 0 0
BIO RAD LABS INC CL A 090572207 78,501 103,896 SH   DFND 1 103,896 0 0
BIOGEN INC COM 09062X103 35,988 150,000 SH   DFND 1 150,000 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 177,028 1,284,580 SH   DFND 1 1,284,580 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 11,044 125,000 SH   DFND 1 125,000 0 0
BK OF AMERICA CORP COM 060505104 27,290 613,389 SH   DFND 1 613,389 0 0
BLACKLINE INC COM 09239B109 14,781 142,754 SH   DFND 1 142,754 0 0
BLACKSTONE INC COM 09260D107 10,491 81,078 SH   DFND 1 81,078 0 0
BLINK CHARGING CO COM 09354A100 206 7,762 SH   DFND 1 7,762 0 0
BLOCK INC CL A 852234103 14,312 88,615 SH   DFND 1 88,615 0 0
BLOOM ENERGY CORP COM CL A 093712107 301 13,739 SH   DFND 1 13,739 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 26,778 250,000 SH   DFND 1 250,000 0 0
BOOKING HOLDINGS INC COM 09857L108 13,162 5,486 SH   DFND 1 5,486 0 0
BORGWARNER INC COM 099724106 1,056 23,432 SH   DFND 1 23,432 0 0
BOSTON SCIENTIFIC CORP COM 101137107 90,357 2,127,059 SH   DFND 1 2,127,059 0 0
BRISTOL-MYERS SQUIBB CO COM 110122108 64,588 1,035,901 SH   DFND 1 1,035,901 0 0
BROADCOM INC COM 11135F101 783 1,177 SH   DFND 1 1,177 0 0
CANADIAN NAT RES LTD COM 136385101 30,715 644,149 SH   DFND 1 644,149 0 0
CANNAE HLDGS INC COM 13765N107 17,683 503,086 SH   DFND 1 503,086 0 0
CANOO INC COM CL A 13803R102 195 25,218 SH   DFND 1 25,218 0 0
CARRIER GLOBAL CORPORATION COM 14448C104 783 14,435 SH   DFND 1 14,435 0 0
CASTLE BIOSCIENCES INC COM 14843C105 1,929 44,985 SH   DFND 1 44,985 0 0
CATALENT INC COM 148806102 6,213 48,527 SH   DFND 1 48,527 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 38,640 1,000,000 SH   DFND 1 1,000,000 0 0
CENTENE CORP DEL COM 15135B101 32,270 391,632 SH   DFND 1 391,632 0 0
CERENCE INC COM 156727109 317 4,136 SH   DFND 1 4,136 0 0
CEREVEL THERAPEUTICS HLDNG I COM 15678U128 24,315 750,000 SH   DFND 1 750,000 0 0
CERUS CORP COM 157085101 13,546 1,989,199 SH   DFND 1 1,989,199 0 0
CHANGE HEALTHCARE INC UNIT 99/99/9999 15912K209 38,891 553,452 SH   DFND 1 553,452 0 0
CHARGEPOINT HOLDINGS INC COM CL A 15961R105 1,187 62,322 SH   DFND 1 62,322 0 0
CHART INDS INC COM 16115Q308 1,067 6,692 SH   DFND 1 6,692 0 0
CHEGG INC NOTE 0.125% 3/1 163092AD1 1,733 1,750,000 SH   DFND 1 1,750,000 0 0
CHEMED CORP NEW COM 16359R103 7,163 13,539 SH   DFND 1 13,539 0 0
CHUBB LIMITED COM H1467J104 199,541 1,032,232 SH   DFND 1 1,032,232 0 0
CITIGROUP INC COM NEW 172967424 14,790 244,915 SH   DFND 1 244,915 0 0
CITIZENS FINL GROUP INC COM 174610105 19,203 406,411 SH   DFND 1 406,411 0 0
CITRIX SYS INC COM 177376100 783 8,277 SH   DFND 1 8,277 0 0
COGNEX CORP COM 192422103 7,500 96,450 SH   DFND 1 96,450 0 0
CONMED CORP COM 207410101 1,413 9,969 SH   DFND 1 9,969 0 0
CONSTELLIUM SE CL A SHS F21107101 265 14,784 SH   DFND 1 14,784 0 0
COOPER COS INC COM NEW 216648402 77,715 185,504 SH   DFND 1 185,504 0 0
COUPA SOFTWARE INC COM 22266L106 52,028 329,185 SH   DFND 1 329,185 0 0
CRITEO S A SPONS ADS 226718104 7,749 199,345 SH   DFND 1 199,345 0 0
CROWDSTRIKE HLDGS INC CL A 22788C105 102,742 501,791 SH   DFND 1 501,791 0 0
CS DISCO INC COM 126327105 5,480 153,289 SH   DFND 1 153,289 0 0
CSG SYS INTL INC NOTE 4.250% 3/1 126349AF6 28,671 27,000,000 SH   DFND 1 27,000,000 0 0
CUMMINS INC COM 231021106 1,056 4,841 SH   DFND 1 4,841 0 0
CURIS INC COM NEW 231269200 3,402 714,700 SH   DFND 1 714,700 0 0
CVS HEALTH CORP COM 126650100 82,279 797,585 SH   DFND 1 797,585 0 0
CYBERARK SOFTWARE LTD NOTE 11/1 23248VAB1 3,795 3,000,000 SH   DFND 1 3,000,000 0 0
CYBERARK SOFTWARE LTD SHS M2682V108 128,898 743,870 SH   DFND 1 743,870 0 0
CYTOKINETICS INC COM NEW 23282W605 167,368 3,671,969 SH   DFND 1 3,671,969 0 0
DANA INC COM 235825205 348 15,233 SH   DFND 1 15,233 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 1,593 163,100 SH   DFND 1 163,100 0 0
DENALI THERAPEUTICS INC COM 24823R105 2,401 53,835 SH   DFND 1 53,835 0 0
DEXCOM INC COM 252131107 23,935 44,576 SH   DFND 1 44,576 0 0
DEXCOM INC NOTE 0.250%11/1 252131AK3 8,939 7,500,000 SH   DFND 1 7,500,000 0 0
DIDI GLOBAL INC SPONSORED ADS 23292E108 1,056 212,061 SH   DFND 1 212,061 0 0
DIODES INC COM 254543101 387 3,525 SH   DFND 1 3,525 0 0
DOCUSIGN INC COM 256163106 60,328 396,089 SH   DFND 1 396,089 0 0
DOLBY LABORATORIES INC COM CL A 25659T107 92,042 966,626 SH   DFND 1 966,626 0 0
DOLLAR GEN CORP NEW COM 256677105 4,217 17,882 SH   DFND 2 17,882 0 0
DUN & BRADSTREET HLDGS INC COM 26484T106 4,850 236,714 SH   DFND 2 236,714 0 0
EAST WEST BANCORP INC COM 27579R104 14,525 184,609 SH   DFND 1 184,609 0 0
EATON CORP PLC SHS G29183103 783 4,531 SH   DFND 1 4,531 0 0
EBAY INC. COM 278642103 8,686 130,614 SH   DFND 1 130,614 0 0
EDWARDS LIFESCIENCES CORP COM 28176E108 12,253 94,583 SH   DFND 1 94,583 0 0
ELASTIC N V ORD SHS N14506104 132,683 1,077,938 SH   DFND 1 1,077,938 0 0
ELECTRAMECCANICA VEHS CORP COM NEW 284849205 28 12,139 SH   DFND 1 12,139 0 0
ELECTRIC LAST MILE SOLUTNS I CLASS A COM 28489L104 97 13,759 SH   DFND 1 13,759 0 0
EMERSON ELEC CO COM 291011104 16,199 174,234 SH   DFND 1 174,234 0 0
ENCOMPASS HEALTH CORP COM 29261A100 59,331 909,154 SH   DFND 1 909,154 0 0
ENERSYS COM 29275Y102 2,892 36,580 SH   DFND 1 36,580 0 0
ENOVIX CORPORATION COM 293594107 729 26,710 SH   DFND 1 26,710 0 0
ENPHASE ENERGY INC COM 29355A107 783 4,280 SH   DFND 1 4,280 0 0
ENTERPRISE FINL SVCS CORP COM 293712105 9,223 195,869 SH   DFND 1 195,869 0 0
ENVISTA HOLDINGS CORPORATION COM 29415F104 83,684 1,857,166 SH   DFND 1 1,857,166 0 0
EPAM SYS INC COM 29414B104 24,701 36,952 SH   DFND 1 36,952 0 0
ESQUIRE FINL HLDGS INC COM 29667J101 749 23,774 SH   DFND 1 23,774 0 0
ESSENT GROUP LTD COM G3198U102 98,891 2,172,000 SH   DFND 1 2,172,000 0 0
ESTABLISHMENT LABS HLDGS INC COM G31249108 666 9,847 SH   DFND 1 9,847 0 0
EURONET WORLDWIDE INC COM 298736109 1,251 10,500 SH   DFND 2 10,500 0 0
EVERBRIDGE INC COM 29978A104 74,879 1,112,124 SH   DFND 1 1,112,124 0 0
EVEREST RE GROUP LTD COM G3223R108 69,370 253,250 SH   DFND 1 253,250 0 0
EVGO INC CL A COM 30052F100 484 48,649 SH   DFND 1 48,649 0 0
EVOLENT HEALTH INC CL A 30050B101 1,084 39,188 SH   DFND 1 39,188 0 0
EXELIXIS INC COM 30161Q104 80,471 4,402,147 SH   DFND 1 4,402,147 0 0
FARADAY FUTRE INTLGT ELCTR I COM 307359109 317 59,651 SH   DFND 1 59,651 0 0
FERGUSON PLC NEW SHS G3421J106 5,572,147 262,157 SH   DFND 1 262,157 0 0
FIDELITY NATL INFORMATION SV COM 31620M106 19,680 180,302 SH   DFND 2 180,302 0 0
FIRST AMERN FINL CORP COM 31847R102 40,640 519,500 SH   DFND 1 519,500 0 0
FIRST REP BK SAN FRANCISCO C COM 33616C100 5,883 28,490 SH   DFND 1 28,490 0 0
FIRST SOLAR INC COM 336433107 726 8,326 SH   DFND 1 8,326 0 0
FISERV INC COM 337738108 19,517 188,040 SH   DFND 1 188,040 0 0
FISKER INC CL A COM STK 33813J106 858 54,569 SH   DFND 1 54,569 0 0
FIVE9 INC COM 338307101 153,796 1,119,985 SH   DFND 1 1,119,985 0 0
FREYR BATTERY SHS L4135L100 239 21,412 SH   DFND 1 21,412 0 0
FUELCELL ENERGY INC COM 35952H601 149 28,710 SH   DFND 1 28,710 0 0
FULCRUM THERAPEUTICS INC COM 359616109 8,845 500,000 SH   DFND 1 500,000 0 0
GARMIN LTD SHS H2906T109 1,150 8,446 SH   DFND 1 8,446 0 0
GENERAC HLDGS INC COM 368736104 783 2,224 SH   DFND 1 2,224 0 0
GENERAL DYNAMICS CORP COM 369550108 2,208 10,591 SH   DFND 2 10,591 0 0
GENTEX CORP COM 371901109 871 24,979 SH   DFND 1 24,979 0 0
GLOBAL BLOOD THERAPEUTICS IN COM 37890U108 26,952 920,810 SH   DFND 1 920,810 0 0
GLOBUS MED INC CL A 379577208 54,454 754,204 SH   DFND 1 754,204 0 0
GOLUB CAP BDC INC COM 38173M102 4,444 287,850 SH   DFND 1 287,850 0 0
GUARDANT HEALTH INC COM 40131M109 13,048 130,458 SH   DFND 1 130,458 0 0
HDFC BANK LTD SPONSORED ADS 40415F101 637 9,786 SH   DFND 1 9,786 0 0
HEALTH CATALYST INC COM 42225T107 277 7,000 SH   DFND 1 7,000 0 0
HEALTHEQUITY INC COM 42226A107 476 10,770 SH   DFND 1 10,770 0 0
HOLOGIC INC COM 436440101 15,154 197,937 SH   DFND 1 197,937 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 177,183 1,644,241 SH   DFND 1 1,644,241 0 0
HUBBELL INC COM 443510607 783 3,760 SH   DFND 1 3,760 0 0
HUBSPOT INC COM 443573100 165,270 250,732 SH   DFND 1 250,732 0 0
HYLIION HOLDINGS CORP COMMON STOCK 449109107 198 31,874 SH   DFND 1 31,874 0 0
HYZON MOTORS INC COM CL A 44951Y102 170 26,153 SH   DFND 1 26,153 0 0
IAC INTERACTIVECORP NEW COM NEW 44891N208 19,442 148,741 SH   DFND 1 148,741 0 0
ICON PLC SHS G4705A100 32,221 104,039 SH   DFND 1 104,039 0 0
IDEANOMICS INC COM 45166V106 63 52,558 SH   DFND 1 52,558 0 0
IGM BIOSCIENCES INC COM 449585108 3,122 106,436 SH   DFND 1 106,436 0 0
II-VI INC COM 902104108 568 8,311 SH   DFND 1 8,311 0 0
ILLUMINA INC COM 452327109 344 904 SH   DFND 1 904 0 0
IMPINJ INC COM 453204109 5,191 58,527 SH   DFND 1 58,527 0 0
INCYTE CORP COM 45337C102 37,095 505,386 SH   DFND 1 505,386 0 0
INDIE SEMICONDUCTOR INC CLASS A COM 45569U101 165 13,737 SH   DFND 1 13,737 0 0
INFINITY PHARMACEUTICALS INC COM 45665G303 11,250 5,000,000 SH   DFND 1 5,000,000 0 0
INNOVIZ TECHNOLOGIES LTD SHS M5R635108 90 14,120 SH   DFND 1 14,120 0 0
INSMED INC COM PAR $.01 457669307 48,983 1,798,209 SH   DFND 1 1,798,209 0 0
INSPIRE MED SYS INC COM 457730109 477 2,075 SH   DFND 1 2,075 0 0
INTERCONTINENTAL EXCHANGE IN COM 45866F104 20,997 153,523 SH   DFND 1 153,523 0 0
INTRA-CELLULAR THERAPIES INC COM 46116X101 4,801 91,735 SH   DFND 1 91,735 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602 12,309 34,259 SH   DFND 1 34,259 0 0
IPG PHOTONICS CORP COM 44980X109 719 4,174 SH   DFND 1 4,174 0 0
IQIYI INC NOTE 2.000% 4/0 46267XAD0 73 100,000 SH   DFND 1 100,000 0 0
ITRON INC COM 465741106 972 14,185 SH   DFND 1 14,185 0 0
IVERIC BIO INC COM 46583P102 31,096 1,859,817 SH   DFND 1 1,859,817 0 0
JAMES RIV GROUP LTD COM G5005R107 25,929 900,000 SH   DFND 1 900,000 0 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105 44,590 350,000 SH   DFND 1 350,000 0 0
JD.COM INC SPON ADR CL A 47215P106 864 12,335 SH   DFND 1 12,335 0 0
JOBY AVIATION INC COMMON STOCK G65163100 466 63,776 SH   DFND 1 63,776 0 0
JOHNSON & JOHNSON COM 478160104 50,393 294,575 SH   DFND 1 294,575 0 0
JOHNSON CTLS INTL PLC SHS G51502105 3,426 42,130 SH   DFND 1 42,130 0 0
JPMORGAN CHASE & CO COM 46625H100 38,791 244,968 SH   DFND 1 244,968 0 0
KE HLDGS INC SPONSORED ADS 482497104 319 15,861 SH   DFND 1 15,861 0 0
KLA CORP COM NEW 482480100 182,281 423,801 SH   DFND 1 423,801 0 0
KORNIT DIGITAL LTD SHS M6372Q113 68,036 446,873 SH   DFND 1 446,873 0 0
LABORATORY CORP AMER HLDGS COM NEW 50540R409 9,384 29,864 SH   DFND 1,2 29,864 0 0
LANTHEUS HLDGS INC COM 516544103 1,316 45,543 SH   DFND 1 45,543 0 0
LATTICE SEMICONDUCTOR CORP COM 518415104 161,661 2,097,857 SH   DFND 1 2,097,857 0 0
LEAR CORP COM NEW 521865204 1,056 5,773 SH   DFND 1 5,773 0 0
LI AUTO INC SPONSORED ADS 50202M102 1,839 57,292 SH   DFND 1 57,292 0 0
LIBERTY MEDIA CORP DEL COM SER C FRMLA 531229854 16,113 254,791 SH   DFND 1 254,791 0 0
LI-CYCLE HOLDINGS CORP COMMON SHARES 50202P105 299 30,008 SH   DFND 1 30,008 0 0
LILIUM N V CLASS A ORD SHS N52586109 208 30,004 SH   DFND 1 30,004 0 0
LILLY ELI & CO COM 532457108 12,993 47,040 SH   DFND 1 47,040 0 0
LINDE PLC SHS G5494J103 4,459 11,539 SH   DFND 1 11,539 0 0
LITHIUM AMERS CORP NEW COM NEW 53680Q207 726 22,108 SH   DFND 1 22,108 0 0
LITTELFUSE INC COM 537008104 34,996 111,212 SH   DFND 1 111,212 0 0
LIVANOVA PLC SHS G5509L101 64,582 738,666 SH   DFND 1 738,666 0 0
LIVE NATION ENTERTAINMENT IN NOTE 2.500% 3/1 538034AQ2 1,810 1,000,000 SH   DFND 1 1,000,000 0 0
LIVENT CORP COM 53814L108 1,017 41,714 SH   DFND 1 41,714 0 0
LIVERAMP HLDGS INC COM 53815P108 10,963 228,642 SH   DFND 1 228,642 0 0
LOGITECH INTL S A SHS H50430232 17,482 217,101 SH   DFND 1 217,101 0 0
LORDSTOWN MOTORS CORP COM CL A 54405Q100 70 20,300 SH   DFND 1 20,300 0 0
LPL FINL HLDGS INC COM 50212V100 20,789 129,858 SH   DFND 1 129,858 0 0
LUCID GROUP INC COM 549498103 1,839 48,332 SH   DFND 1 48,332 0 0
LUMENTUM HLDGS INC COM 55024U109 2,534 23,961 SH   DFND 1 23,961 0 0
LUMENTUM HLDGS INC NOTE 0.500%12/1 55024UAD1 6,868 5,500,000 SH   DFND 1 5,500,000 0 0
LUMINAR TECHNOLOGIES INC COM CL A 550424105 646 38,182 SH   DFND 1 38,182 0 0
LYFT INC CL A COM 55087P104 1,056 24,714 SH   DFND 1 24,714 0 0
MAGNA INTL INC COM 559222401 1,192 13,052 SH   DFND 1 13,052 0 0
MARKEL CORP COM 570535104 123,462 100,050 SH   DFND 1 100,050 0 0
MARSH & MCLENNAN COS INC COM 571748102 184,249 1,060,000 SH   DFND 1 1,060,000 0 0
MARVELL TECHNOLOGY INC COM 573874104 290,915 3,325,125 SH   DFND 1 3,325,125 0 0
MASIMO CORP COM 574795100 3,965 13,544 SH   DFND 1 13,544 0 0
MASTEC INC COM 576323109 537 5,818 SH   DFND 1 5,818 0 0
MASTERCARD INCORPORATED CL A 57636Q104 85,660 238,396 SH   DFND 1 238,396 0 0
MATCH GROUP INC NEW COM 57667L107 58,614 443,205 SH   DFND 1 443,205 0 0
MEDTRONIC PLC SHS G5960L103 22,462 217,132 SH   DFND 1 217,132 0 0
MERCADOLIBRE INC COM 58733R102 45,762 33,938 SH   DFND 1 33,938 0 0
MERIDIAN BIOSCIENCE INC COM 589584101 683 33,463 SH   DFND 1 33,463 0 0
MERIT MED SYS INC COM 589889104 38,353 615,621 SH   DFND 1 615,621 0 0
META PLATFORMS INC CL A 30303M102 465,558 1,384,146 SH   DFND 1 1,384,146 0 0
MICROCHIP TECHNOLOGY INC. COM 595017104 783 8,994 SH   DFND 1 8,994 0 0
MICRON TECHNOLOGY INC COM 595112103 239,559 2,571,757 SH   DFND 1 2,571,757 0 0
MICROSOFT CORP COM 594918104 1,272,897 3,784,778 SH   DFND 1,2 3,784,778 0 0
MICROSOFT CORP COM 594918104 479,256 1,425,000 SH Call DFND 1 1,425,000 0 0
MICROVAST HOLDINGS INC COM 59516C106 313 55,267 SH   DFND 1 55,267 0 0
MIRATI THERAPEUTICS INC COM 60468T105 3,911 26,662 SH   DFND 1 26,662 0 0
MKS INSTRS INC COM 55306N104 26,726 153,450 SH   DFND 1 153,450 0 0
MODIVCARE INC COM 60783X104 52,078 351,191 SH   DFND 1 351,191 0 0
MOHAWK INDS INC COM 608190104 11,128 61,084 SH   DFND 1 61,084 0 0
MOLINA HEALTHCARE INC COM 60855R100 88,569 278,449 SH   DFND 1 278,449 0 0
MONGODB INC CL A 60937P106 127,291 240,466 SH   DFND 1 240,466 0 0
MONOLITHIC PWR SYS INC COM 609839105 61,940 125,555 SH   DFND 1 125,555 0 0
MORGAN STANLEY COM NEW 617446448 13,516 137,695 SH   DFND 1 137,695 0 0
MORPHIC HLDG INC COM 61775R105 15,399 325,000 SH   DFND 1 325,000 0 0
MP MATERIALS CORP COM CL A 553368101 1,486 32,712 SH   DFND 1 32,712 0 0
NANOSTRING TECHNOLOGIES INC COM 63009R109 49,986 1,183,652 SH   DFND 1 1,183,652 0 0
NATERA INC COM 632307104 11,928 127,718 SH   DFND 1 127,718 0 0
NATIONAL INSTRS CORP COM 636518102 451 10,326 SH   DFND 1 10,326 0 0
NETEASE INC SPONSORED ADS 64110W102 572 5,618 SH   DFND 1 5,618 0 0
NETFLIX INC COM 64110L106 190,049 315,466 SH   DFND 1 315,466 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 2,920 34,287 SH   DFND 1 34,287 0 0
NEVRO CORP COM 64157F103 3,782 46,647 SH   DFND 1 46,647 0 0
NIKOLA CORP COM 654110105 424 42,970 SH   DFND 1 42,970 0 0
NIO INC SPON ADS 62914V106 3,011 95,049 SH   DFND 1 95,049 0 0
NIU TECHNOLOGIES ADS 65481N100 226 14,029 SH   DFND 1 14,029 0 0
NVIDIA CORPORATION COM 67066G104 524,220 1,782,396 SH   DFND 1 1,782,396 0 0
NXP SEMICONDUCTORS N V COM N6596X109 1,953 8,575 SH   DFND 1 8,575 0 0
OAK STR HEALTH INC COM 67181A107 2,833 85,500 SH   DFND 1 85,500 0 0
OCULAR THERAPEUTIX INC COM 67576A100 263 37,790 SH   DFND 1 37,790 0 0
OKTA INC CL A 679295105 179,088 798,893 SH   DFND 1 798,893 0 0
OMNICELL COM COM 68213N109 1,062 5,887 SH   DFND 1 5,887 0 0
ON SEMICONDUCTOR CORP COM 682189105 162,158 2,387,490 SH   DFND 1 2,387,490 0 0
ONCOCYTE CORP COM 68235C107 231 106,422 SH   DFND 1 106,422 0 0
OPTION CARE HEALTH INC COM NEW 68404L201 56,601 1,990,195 SH   DFND 1 1,990,195 0 0
ORACLE CORP COM 68389X105 3,782 43,371 SH   DFND 2 43,371 0 0
OREILLY AUTOMOTIVE INC COM 67103H107 2,981 4,221 SH   DFND 2 4,221 0 0
OTONOMO TECHNOLOGIES LTD ORDINARY SHARES M7571L103 57 13,962 SH   DFND 1 13,962 0 0
OUSTER INC COM 68989M103 94 18,122 SH   DFND 1 18,122 0 0
OWENS & MINOR INC NEW COM 690732102 1,437 33,026 SH   DFND 1 33,026 0 0
PACIFIC PREMIER BANCORP COM 69478X105 6,927 173,053 SH   DFND 1 173,053 0 0
PACIRA BIOSCIENCES INC COM 695127100 1,045 17,368 SH   DFND 1 17,368 0 0
PACWEST BANCORP DEL COM 695263103 10,568 233,964 SH   DFND 1 233,964 0 0
PALO ALTO NETWORKS INC NOTE 0.375% 6/0 697435AF2 7,218 3,800,000 SH   DFND 1 3,800,000 0 0
PAYCOM SOFTWARE INC COM 70432V102 18,149 43,713 SH   DFND 1 43,713 0 0
PENUMBRA INC COM 70975L107 4,463 15,534 SH   DFND 1 15,534 0 0
PG&E CORP UNIT 99/99/9999 69331C140 115,680 1,000,000 SH   DFND 1 1,000,000 0 0
PHOENIX NEW MEDIA LTD SPONSORED ADS 71910C103 113 130,876 SH   DFND 1 130,876 0 0
PINTEREST INC CL A 72352L106 16,007 440,357 SH   DFND 1 440,357 0 0
PIONEER NAT RES CO NOTE 0.250% 5/1 723787AP2 1,787 1,000,000 SH   DFND 1 1,000,000 0 0
PLUG POWER INC COM NEW 72919P202 3,505 124,146 SH   DFND 1 124,146 0 0
PNC FINL SVCS GROUP INC COM 693475105 16,240 80,989 SH   DFND 1 80,989 0 0
POWER INTEGRATIONS INC COM 739276103 84,375 908,328 SH   DFND 1 908,328 0 0
PROASSURANCE CORP COM 74267C106 30,360 1,200,000 SH   DFND 1 1,200,000 0 0
PROGRESSIVE CORP COM 743315103 62,540 609,250 SH   DFND 1 609,250 0 0
PROGYNY INC COM 74340E103 915 18,175 SH   DFND 1 18,175 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102 10,377 303,429 SH   DFND 1 303,429 0 0
PROTERRA INC COM 74374T109 204 23,055 SH   DFND 1 23,055 0 0
PTC INC COM 69370C100 783 6,463 SH   DFND 1 6,463 0 0
PURE STORAGE INC CL A 74624M102 120,911 3,714,635 SH   DFND 1 3,714,635 0 0
QIAGEN NV SHS NEW N72482123 2,878 46,522 SH   DFND 1 46,522 0 0
QORVO INC COM 74736K101 2,918 18,656 SH   DFND 1 18,656 0 0
QUALCOMM INC COM 747525103 204,553 1,118,571 SH   DFND 1 1,118,571 0 0
QUANTA SVCS INC COM 74762E102 783 6,829 SH   DFND 1 6,829 0 0
QUANTUMSCAPE CORP COM CL A 74767V109 1,725 77,716 SH   DFND 1 77,716 0 0
QUOTIENT LTD SHS G73268107 23,962 9,251,653 SH   DFND 1 9,251,653 0 0
R1 RCM INC COM 749397105 14,319 561,737 SH   DFND 1 561,737 0 0
RECRO PHARMA INC COM 75629F109 514 300,747 SH   DFND 1 300,747 0 0
REE AUTOMOTIVE LTD CLASS A ORD SHS M8287R103 184 33,092 SH   DFND 1 33,092 0 0
REGAL REXNORD CORPORATION COM 758750103 1,361 8,000 SH   DFND 1 8,000 0 0
REGENERON PHARMACEUTICALS COM 75886F107 107,358 170,000 SH   DFND 1 170,000 0 0
REINSURANCE GRP OF AMERICA I COM NEW 759351604 59,398 542,500 SH   DFND 1 542,500 0 0
RENAISSANCERE HLDGS LTD COM G7496G103 133,830 790,353 SH   DFND 1,2 790,353 0 0
RESIDEO TECHNOLOGIES INC COM 76118Y104 1,101 42,305 SH   DFND 1 42,305 0 0
REVANCE THERAPEUTICS INC COM 761330109 36,878 2,259,700 SH   DFND 1 2,259,700 0 0
RINGCENTRAL INC NOTE 3/0 76680RAF4 7,556 8,000,000 SH   DFND 1 8,000,000 0 0
RLI CORP COM 749607107 30,828 275,000 SH   DFND 1 275,000 0 0
ROBLOX CORP CL A 771049103 126,472 1,225,977 SH   DFND 1 1,225,977 0 0
ROCKWELL AUTOMATION INC COM 773903109 20,019 57,387 SH   DFND 1 57,387 0 0
ROMEO POWER INC COM 776153108 90 24,669 SH   DFND 1 24,669 0 0
RYAN SPECIALTY GROUP HLDGS I CL A 78351F107 17,552 435,000 SH   DFND 1 435,000 0 0
S&P GLOBAL INC COM 78409V104 28,198 59,751 SH   DFND 1 59,751 0 0
SALESFORCE COM INC COM 79466L302 98,662 388,235 SH   DFND 1 388,235 0 0
SEA LTD NOTE 0.250% 9/1 81141RAG5 12,942 14,000,000 SH   DFND 1 14,000,000 0 0
SEA LTD SPONSORD ADS 81141R100 39,993 178,772 SH   DFND 1 178,772 0 0
SEAGATE TECHNOLOGY HLDNGS PL ORD SHS G7997R103 265,870 2,353,246 SH   DFND 1 2,353,246 0 0
SEAGEN INC COM 81181C104 82,981 536,748 SH   DFND 1 536,748 0 0
SEMTECH CORP COM 816850101 449 5,046 SH   DFND 1 5,046 0 0
SENSATA TECHNOLOGIES HLDG PL SHS G8060N102 20,396 330,623 SH   DFND 1,2 330,623 0 0
SERVICE CORP INTL COM 817565104 28,241 397,823 SH   DFND 1 397,823 0 0
SERVICENOW INC COM 81762P102 263,134 405,377 SH   DFND 1 405,377 0 0
SHIFT TECHNOLOGIES INC CL A 82452T107 2,571 753,820 SH   DFND 1 753,820 0 0
SHOALS TECHNOLOGIES GROUP IN CL A 82489W107 317 13,064 SH   DFND 1 13,064 0 0
SHOCKWAVE MED INC COM 82489T104 412 2,310 SH   DFND 1 2,310 0 0
SHOPIFY INC CL A 82509L107 33,235 24,129 SH   DFND 1 24,129 0 0
SIGNATURE BK NEW YORK N Y COM 82669G104 46,843 144,814 SH   DFND 1 144,814 0 0
SILICON LABORATORIES INC COM 826919102 650 3,147 SH   DFND 1 3,147 0 0
SILICON LABORATORIES INC NOTE 0.625% 6/1 826919AD4 17,477 9,941,000 SH   DFND 1 9,941,000 0 0
SKYWORKS SOLUTIONS INC COM 83088M102 2,226 14,347 SH   DFND 1 14,347 0 0
SLR INVESTMENT CORP COM 83413U100 5,068 275,000 SH   DFND 1 275,000 0 0
SLR SENIOR INVESTMENT CORP COM 83416M105 310 22,149 SH   DFND 1 22,149 0 0
SMARTSHEET INC COM CL A 83200N103 84,447 1,090,348 SH   DFND 1 1,090,348 0 0
SMITH A O CORP COM 831865209 783 9,121 SH   DFND 1 9,121 0 0
SNAP INC CL A 83304A106 214,551 4,561,998 SH   DFND 1 4,561,998 0 0
SNOWFLAKE INC CL A 833445109 58,916 173,921 SH   DFND 1 173,921 0 0
SOCIEDAD QUIMICA Y MINERA DE SPON ADR SER B 833635105 1,940 38,467 SH   DFND 1 38,467 0 0
SOLAREDGE TECHNOLOGIES INC COM 83417M104 2,429 8,656 SH   DFND 1 8,656 0 0
SPOTIFY TECHNOLOGY S A SHS L8681T102 29,371 125,499 SH   DFND 1 125,499 0 0
SS&C TECHNOLOGIES HLDGS INC COM 78467J100 32,608 397,760 SH   DFND 1 397,760 0 0
SSR MNG INC NOTE 2.500% 4/0 784730AB9 10,647 8,539,000 SH   DFND 1 8,539,000 0 0
STELLANTIS N.V SHS N82405106 20,107 954,175 SH   DFND 2 954,175 0 0
STEM INC COM 85859N102 215 11,313 SH   DFND 1 11,313 0 0
STEREOTAXIS INC COM NEW 85916J409 475 76,687 SH   DFND 1 76,687 0 0
STERIS PLC SHS USD G8473T100 100,645 413,481 SH   DFND 1 413,481 0 0
STITCH FIX INC COM CL A 860897107 4,464 235,942 SH   DFND 1 235,942 0 0
STRIDE INC NOTE 1.125% 9/0 86333MAA6 1,467 1,500,000 SH   DFND 1 1,500,000 0 0
STRYKER CORPORATION COM 863667101 11,568 43,257 SH   DFND 1 43,257 0 0
SUMMIT THERAPEUTICS INC COM 86627T108 16,457 6,117,911 SH   DFND 1 6,117,911 0 0
SUNNOVA ENERGY INTL INC. COM 86745K104 245 8,791 SH   DFND 1 8,791 0 0
SUNPOWER CORP COM 867652406 283 13,545 SH   DFND 1 13,545 0 0
SUNRUN INC COM 86771W105 556 16,208 SH   DFND 1 16,208 0 0
SUPERNUS PHARMACEUTICALS NOTE 0.625% 4/0 868459AD0 13,327 13,453,000 SH   DFND 1 13,453,000 0 0
SUPERNUS PHARMACEUTICALS INC COM 868459108 18,311 627,945 SH   DFND 1 627,945 0 0
SURGERY PARTNERS INC COM 86881A100 26,084 488,369 SH   DFND 1 488,369 0 0
SVB FINANCIAL GROUP COM 78486Q101 12,828 18,913 SH   DFND 1 18,913 0 0
SYNEOS HEALTH INC CL A 87166B102 8,358 81,401 SH   DFND 1 81,401 0 0
TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADS 874039100 12,510 103,983 SH   DFND 2 103,983 0 0
TAKE-TWO INTERACTIVE SOFTWAR COM 874054109 7,320 41,191 SH   DFND 1 41,191 0 0
TANDEM DIABETES CARE INC COM NEW 875372203 2,284 15,173 SH   DFND 1 15,173 0 0
TAYLOR MORRISON HOME CORP COM 87724P106 24,186 691,818 SH   DFND 1 691,818 0 0
TE CONNECTIVITY LTD SHS H84989104 104,087 645,140 SH   DFND 1 645,140 0 0
TELEFLEX INCORPORATED COM 879369106 4,666 14,206 SH   DFND 1 14,206 0 0
TENABLE HLDGS INC COM 88025T102 106,328 1,930,782 SH   DFND 1 1,930,782 0 0
TESLA INC COM 88160R101 85,423 80,833 SH   DFND 1 80,833 0 0
TEXAS INSTRS INC COM 882508104 1,839 9,759 SH   DFND 1 9,759 0 0
THE LION ELECTRIC COMPANY COMMON STOCK 536221104 199 20,010 SH   DFND 1 20,010 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102 15,872 23,788 SH   DFND 1 23,788 0 0
T-MOBILE US INC COM 872590104 34,025 293,371 SH   DFND 1 293,371 0 0
TORONTO DOMINION BK ONT COM NEW 891160509 23,758 274,607 SH   DFND 1 274,607 0 0
TRANE TECHNOLOGIES PLC SHS G8994E103 783 3,876 SH   DFND 1 3,876 0 0
TRAVELERS COMPANIES INC COM 89417E109 102,077 652,538 SH   DFND 1 652,538 0 0
TRIMBLE INC COM 896239100 1,056 12,113 SH   DFND 1 12,113 0 0
TRIPADVISOR INC COM 896945201 123,414 4,527,306 SH   DFND 1 4,527,306 0 0
TUSIMPLE HLDGS INC CL A 90089L108 807 22,498 SH   DFND 1 22,498 0 0
TWILIO INC CL A 90138F102 78,010 296,233 SH   DFND 1 296,233 0 0
TWITTER INC COM 90184L102 11,181 258,689 SH   DFND 1 258,689 0 0
UBER TECHNOLOGIES INC COM 90353T100 87,925 2,096,948 SH   DFND 1 2,096,948 0 0
UBS GROUP AG SHS H42097107 16,933 984,547 SH   DFND 1 984,547 0 0
UNIQURE NV SHS N90064101 274 13,200 SH   DFND 1 13,200 0 0
UNITED RENTALS INC COM 911363109 34,914 105,072 SH   DFND 1 105,072 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102 113,586 525,667 SH   DFND 1 525,667 0 0
UNITEDHEALTH GROUP INC COM 91324P102 88,021 175,292 SH   DFND 1 175,292 0 0
UNITY SOFTWARE INC COM 91332U101 17,805 124,521 SH   DFND 1 124,521 0 0
UPSTART HLDGS INC COM 91680M107 8,660 57,237 SH   DFND 1 57,237 0 0
US FOODS HLDG CORP COM 912008109 31,512 904,733 SH   DFND 1 904,733 0 0
VALENS SEMICONDUCTOR LTD ORDINARY SHARES M9607U115 80 10,359 SH   DFND 1 10,359 0 0
VELODYNE LIDAR INC COM 92259F101 96 20,747 SH   DFND 1 20,747 0 0
VEONEER INC COM 92336X109 420 11,828 SH   DFND 1 11,828 0 0
VERICEL CORP COM 92346J108 674 17,160 SH   DFND 1 17,160 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 82,350 375,000 SH   DFND 1 375,000 0 0
VERTIV HOLDINGS CO COM CL A 92537N108 1,464 58,614 SH   DFND 1 58,614 0 0
VICOR CORP COM 925815102 435 3,427 SH   DFND 1 3,427 0 0
VISA INC COM CL A 92826C839 37,276 172,008 SH   DFND 1 172,008 0 0
VISHAY INTERTECHNOLOGY INC COM 928298108 248 11,338 SH   DFND 1 11,338 0 0
VISTEON CORP COM NEW 92839U206 662 5,957 SH   DFND 1 5,957 0 0
VMWARE INC CL A COM 928563402 783 6,756 SH   DFND 1 6,756 0 0
VOLTA INC COM CL A 92873V102 219 29,828 SH   DFND 1 29,828 0 0
WEBSTER FINL CORP CONN COM 947890109 8,174 146,379 SH   DFND 1 146,379 0 0
WELLS FARGO CO NEW COM 949746101 11,188 233,187 SH   DFND 1 233,187 0 0
WESTERN ALLIANCE BANCORP COM 957638109 10,229 95,024 SH   DFND 1 95,024 0 0
WESTERN DIGITAL CORP. COM 958102105 75,848 1,163,127 SH   DFND 1 1,163,127 0 0
WORKDAY INC CL A 98138H101 112,076 410,264 SH   DFND 1 410,264 0 0
WORKHORSE GROUP INC COM NEW 98138J206 72 16,473 SH   DFND 1 16,473 0 0
XENON PHARMACEUTICALS INC COM 98420N105 52,734 1,688,044 SH   DFND 1 1,688,044 0 0
XILINX INC COM 983919101 3,179 14,993 SH   DFND 1 14,993 0 0
XL FLEET CORP COM CL A 9837FR100 49 14,724 SH   DFND 1 14,724 0 0
XOMETRY INC CLASS A COM 98423F109 5,107 99,644 SH   DFND 1 99,644 0 0
XOS INC COMMON STOCK 98423B108 54 17,204 SH   DFND 1 17,204 0 0
XPENG INC ADS 98422D105 4,798 95,340 SH   DFND 1 95,340 0 0
YANDEX N V SHS CLASS A N97284108 12,769 211,054 SH   DFND 1 211,054 0 0
Y-MABS THERAPEUTICS INC COM 984241109 22,332 1,377,671 SH   DFND 1 1,377,671 0 0
ZAI LAB LTD ADR 98887Q104 8,190 130,306 SH   DFND 1 130,306 0 0
ZENDESK INC COM 98936J101 127,237 1,220,030 SH   DFND 1 1,220,030 0 0
ZENDESK INC NOTE 0.625% 6/1 98936JAD3 1,797 1,500,000 SH   DFND 1 1,500,000 0 0
ZENTALIS PHARMACEUTICALS INC COM 98943L107 31,046 369,329 SH   DFND 1 369,329 0 0
ZIMMER BIOMET HOLDINGS INC COM 98956P102 16,634 130,936 SH   DFND 1 130,936 0 0
ZOOM VIDEO COMMUNICATIONS IN CL A 98980L101 63,368 344,561 SH   DFND 1 344,561 0 0
ZUORA INC COM CL A 98983V106 20,936 1,120,764 SH   DFND 1 1,120,764 0 0