The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| ADDEX THERAPEUTICS LTD | SHS | 00654J107 | 315 | 50,000 | SH | DFND | 50,000 | 0 | 0 | ||
| ALECTOR INC | COM | 014442107 | 7,012 | 339,569 | SH | DFND | 339,569 | 0 | 0 | ||
| AMRYT PHARMA PLC | SHS | 03217L106 | 4,857 | 449,737 | SH | DFND | 449,737 | 0 | 0 | ||
| APTINYX INC | COM | 03836N103 | 8,785 | 3,290,079 | SH | DFND | 3,290,079 | 0 | 0 | ||
| ARAVIVE INC | COM | 03890D108 | 2,073 | 946,423 | SH | DFND | 946,423 | 0 | 0 | ||
| ARVINAS INC | COM | 04335A105 | 105,921 | 1,289,521 | SH | DFND | 1,289,521 | 0 | 0 | ||
| AVROBIO INC | COM | 05455M100 | 1,215 | 315,550 | SH | DFND | 315,550 | 0 | 0 | ||
| CHIMERIX INC | COM | 16934W106 | 7,874 | 1,224,600 | SH | DFND | 1,224,600 | 0 | 0 | ||
| COGENT BIOSCIENCES INC. | COM | 19240Q201 | 4,303 | 501,530 | SH | DFND | 501,530 | 0 | 0 | ||
| CRINETICS PHARMACEUTICALS INC | COM | 22663K107 | 4,006 | 141,000 | SH | DFND | 141,000 | 0 | 0 | ||
| DECIPHERA PHARMACEUTICALS INC | COM | 24344T101 | 11,818 | 1,209,571 | SH | DFND | 1,209,571 | 0 | 0 | ||
| DICE THERAPEUTICS INC | COM | 23345J104 | 14,090 | 556,693 | SH | DFND | 556,693 | 0 | 0 | ||
| EDGEWISE THERAPEUTICS INC | COM | 28036F105 | 23,740 | 1,553,661 | SH | DFND | 1,553,661 | 0 | 0 | ||
| HARPOON THERAPEUTICS INC | COM | 41358P106 | 23,833 | 3,156,699 | SH | DFND | 3,156,699 | 0 | 0 | ||
| ITERUM THERAPEUTICS PLC | SHS | G6333L101 | 571 | 1,456,303 | SH | DFND | 1,456,303 | 0 | 0 | ||
| OBSEVA SA | COM | H5861P103 | 1,792 | 900,501 | SH | DFND | 900,501 | 0 | 0 | ||
| PASSAGE BIO | COM | 702712100 | 15,862 | 2,497,922 | SH | DFND | 2,497,922 | 0 | 0 | ||
| PDS BIOTECHNOLOGY CORP | COM | 70465T107 | 950 | 117,242 | SH | DFND | 117,242 | 0 | 0 | ||
| RALLYBIO CORPORATION | COM | 75120L100 | 21,957 | 2,301,603 | SH | DFND | 2,301,603 | 0 | 0 | ||
| RENOVACOR CORPORATION | COM | 75989E106 | 5,370 | 697,436 | SH | DFND | 697,436 | 0 | 0 | ||
| SIERRA ONCOLOGY INC | COM | 82640U107 | 8,905 | 409,611 | SH | DFND | 409,611 | 0 | 0 | ||
| X4 PHARMACEUTICALS INC | COM | 98420X103 | 767 | 335,000 | SH | DFND | 335,000 | 0 | 0 | ||