The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABBVIE INC COM 00287Y109 13,448 99,318 SH   SOLE   99,318 0 0
ABERDEEN TOTAL DYNAMIC DIVD COM SH BEN INT 00326L100 2,647 259,000 SH   SOLE   259,000 0 0
ADVANCED MICRO DEVICES INC COM 007903107 4,317 30,000 SH   SOLE   30,000 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 1,348 192,065 SH   SOLE   192,065 0 0
AIR T INC COM 009207101 252 10,004 SH   SOLE   10,004 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 3,052 18,000 SH   SOLE   18,000 0 0
ALPHABET INC CAP STK CL C 02079K107 12,587 4,350 SH   SOLE   4,350 0 0
ALTIMMUNE INC COM NEW 02155H200 2,571 280,700 SH   SOLE   280,700 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206 539 160,000 SH   SOLE   160,000 0 0
AMGEN INC COM 031162100 2,868 12,750 SH   SOLE   12,750 0 0
APPLE INC COM 037833100 2,220 12,500 SH   SOLE   12,500 0 0
APTINYX INC COM 03836N103 152 57,000 SH   SOLE   57,000 0 0
APTIV PLC SHS G6095L109 371 2,250 SH   SOLE   2,250 0 0
ARENA PHARMACEUTICALS INC COM NEW 040047607 465 5,000 SH   SOLE   5,000 0 0
ARGENX SE SPONSORED ADR 04016X101 8,755 25,000 SH   SOLE   25,000 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108 742 12,745 SH   SOLE   12,745 0 0
AT&T INC COM 00206R102 2,276 92,500 SH   SOLE   92,500 0 0
BECTON DICKINSON & CO COM 075887109 503 2,000 SH   SOLE   2,000 0 0
BK OF AMERICA CORP COM 060505104 6,473 145,500 SH   SOLE   145,500 0 0
BOULDER GROWTH & INCOME FD I COM 101507101 1,179 83,000 SH   SOLE   83,000 0 0
BOX INC CL A 10316T104 485 18,500 SH   SOLE   18,500 0 0
BRISTOL-MYERS SQUIBB CO COM 110122108 2,026 32,500 SH   SOLE   32,500 0 0
CITIGROUP INC COM NEW 172967424 4,107 68,000 SH   SOLE   68,000 0 0
DISCOVERY INC COM SER A 25470F104 376 15,990 SH   SOLE   15,990 0 0
EQUILLIUM INC COM 29446K106 708 187,666 SH   SOLE   187,666 0 0
ESPERION THERAPEUTICS INC NE NOTE 4.000%11/1 29664WAB1 211 400,000 PRN   SOLE   400,000 0 0
LILLY ELI & CO COM 532457108 3,107 11,250 SH   SOLE   11,250 0 0
ENERGY TRANSFER L P COM UT LTD PTN 29273V100 774 94,000 SH   SOLE   94,000 0 0
FORD MTR CO DEL COM 345370860 3,505 168,750 SH   SOLE   168,750 0 0
FREEPORT-MCMORAN INC CL B 35671D857 417 10,000 SH   SOLE   10,000 0 0
GENERAL MTRS CO COM 37045V100 4,984 85,000 SH   SOLE   85,000 0 0
GLOBAL X FDS LITHIUM BTRY ETF 37954Y855 422 5,000 SH   SOLE   5,000 0 0
HONEYWELL INTL INC COM 438516106 1,877 9,000 SH Call SOLE   9,000 0 0
ILLINOIS TOOL WKS INC COM 452308109 864 3,500 SH   SOLE   3,500 0 0
IMPEL NEUROPHARMA INC COM 45258K109 2,210 256,027 SH   SOLE   256,027 0 0
INCYTE CORP COM 45337C102 5,138 70,000 SH   SOLE   70,000 0 0
INTEL CORP COM 458140100 1,030 20,000 SH   SOLE   20,000 0 0
INTRA-CELLULAR THERAPIES INC COM 46116X101 18,790 359,000 SH   SOLE   359,000 0 0
INVESCO QQQ TR UNIT SER 1 46090E103 13,925 35,000 SH Put SOLE   35,000 0 0
ISHARES GOLD TR ISHARES NEW 464285204 3,481 100,000 SH   SOLE   100,000 0 0
ISHARES SILVER TR ISHARES 46428Q109 1,452 67,500 SH   SOLE   67,500 0 0
LENSAR INC COM 52634L108 1,676 279,788 SH   SOLE   279,788 0 0
LINEAGE CELL THERAPEUTICS IN COM 53566P109 208 85,000 SH   SOLE   85,000 0 0
MARVELL TECHNOLOGY INC COM 573874104 1,531 17,500 SH   SOLE   17,500 0 0
MATINAS BIOPHARMA HLDGS INC COM 576810105 156 154,500 SH   SOLE   154,500 0 0
MICRON TECHNOLOGY INC COM 595112103 16,534 177,500 SH   SOLE   177,500 0 0
MICRON TECHNOLOGY INC COM 595112103 932 10,000 SH Put SOLE   10,000 0 0
MICROSOFT CORP COM 594918104 841 2,500 SH   SOLE   2,500 0 0
MORGAN STANLEY COM NEW 617446448 1,227 12,500 SH   SOLE   12,500 0 0
NEKTAR THERAPEUTICS COM 640268108 423 31,300 SH   SOLE   31,300 0 0
NOKIA CORP SPONSORED ADR 654902204 933 150,000 SH   SOLE   150,000 0 0
NXP SEMICONDUCTORS N V COM N6596X109 797 3,500 SH   SOLE   3,500 0 0
ONCOCYTE CORP COM 68235C107 26 12,149 SH   SOLE   12,149 0 0
ORACLE CORP COM 68389X105 3,706 42,500 SH   SOLE   42,500 0 0
ORACLE CORP COM 68389X105 1,962 22,500 SH Call SOLE   22,500 0 0
QUALCOMM INC COM 747525103 1,372 7,500 SH   SOLE   7,500 0 0
OVID THERAPEUTICS INC COM 690469101 455 141,701 SH   SOLE   141,701 0 0
PFIZER INC COM 717081103 3,838 65,000 SH   SOLE   65,000 0 0
PROTHENA CORP PLC SHS G72800108 2,964 60,000 SH   SOLE   60,000 0 0
REGENERON PHARMACEUTICALS COM 75886F107 10,862 17,200 SH   SOLE   17,200 0 0
REGENERON PHARMACEUTICALS COM 75886F107 126 200 SH Call SOLE   200 0 0
SEAGEN INC COM 81181C104 2,087 13,500 SH   SOLE   13,500 0 0
SELECT SECTOR SPDR TR SBI CONS STPLS 81369Y308 694 9,000 SH Call SOLE   9,000 0 0
SPDR GOLD TR GOLD SHS 78463V107 4,274 25,000 SH   SOLE   25,000 0 0
TURNING PT BRANDS INC COM 90041L105 4,229 111,926 SH   SOLE   111,926 0 0
VANECK ETF TRUST GOLD MINERS ETF 92189F106 3,683 115,000 SH   SOLE   115,000 0 0
VANECK ETF TRUST JUNIOR GOLD MINE 92189F791 2,306 55,000 SH   SOLE   55,000 0 0
VANGUARD INDEX FDS S&P 500 ETF SHS 922908363 28,377 65,000 SH Put SOLE   65,000 0 0
VERIZON COMMUNICATIONS INC COM 92343V104 2,598 50,000 SH   SOLE   50,000 0 0
VIACOMCBS INC CL B 92556H206 335 11,100 SH   SOLE   11,100 0 0
VIR BIOTECHNOLOGY INC COM 92764N102 837 20,000 SH   SOLE   20,000 0 0
WALGREENS BOOTS ALLIANCE INC COM 931427108 261 5,000 SH   SOLE   5,000 0 0
XENCOR INC COM 98401F105 9,700 241,763 SH   SOLE   241,763 0 0