The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Aerojet Rocketdyne Holdings In Common Stock 007800105 5,251 112,300 SH   SOLE   112,300 0 0
AeroVironment Inc Common Stock 008073108 57,001 918,930 SH   SOLE   918,930 0 0
Align Technology Inc Common Stock 016255101 5,722 8,707 SH   SOLE   8,707 0 0
Allegheny Technologies Inc Common Stock 01741R102 427 26,804 SH   SOLE   26,804 0 0
Alphabet Inc Common Stock 02079K107 49,912 17,249 SH   SOLE   17,249 0 0
Altair Engineering Inc Common Stock 021369103 16,514 213,576 SH   SOLE   213,576 0 0
Amazon.com Inc Common Stock 023135106 14,348 4,303 SH   SOLE   4,303 0 0
AMETEK Inc Common Stock 031100100 5,959 40,524 SH   SOLE   40,524 0 0
ANSYS Inc Common Stock 03662Q105 48,325 120,476 SH   SOLE   120,476 0 0
AquaBounty Technologies Inc Common Stock 03842K200 11,186 5,326,857 SH   SOLE   5,326,857 0 0
Arcturus Therapeutics Holdings Common Stock 03969T109 91,512 2,472,630 SH   SOLE   2,472,630 0 0
Autodesk Inc Common Stock 052769106 15,368 54,652 SH   SOLE   54,652 0 0
Baidu Inc ADR 056752108 30,518 205,110 SH   SOLE   205,110 0 0
Renishaw PLC Common Stock G75006117 16,375 253,100 SH   SOLE   253,100 0 0
CareDx Inc Common Stock 14167L103 165,491 3,638,774 SH   SOLE   3,638,774 0 0
Carpenter Technology Corp Common Stock 144285103 401 13,738 SH   SOLE   13,738 0 0
Castle Biosciences Inc Common Stock 14843C105 52,010 1,213,207 SH   SOLE   1,213,207 0 0
Cellectis SA ADR 15117K103 23,885 2,941,556 SH   SOLE   2,941,556 0 0
Cerus Corp Common Stock 157085101 107,312 15,758,044 SH   SOLE   14,348,816 517,605 891,623
Codexis Inc Common Stock 192005106 101,441 3,244,040 SH   SOLE   3,244,040 0 0
Deere & Co Common Stock 244199105 79,886 232,979 SH   SOLE   232,979 0 0
DuPont de Nemours Inc Common Stock 26614N102 517 6,396 SH   SOLE   6,396 0 0
Eastman Chemical Co Common Stock 277432100 503 4,158 SH   SOLE   4,158 0 0
Editas Medicine Inc Common Stock 28106W103 111,996 4,218,302 SH   SOLE   3,751,074 362,662 104,566
Meta Platforms Inc Common Stock 30303M102 0 0 SH   SOLE   0 0 0
FARO Technologies Inc Common Stock 311642102 5,195 74,199 SH   SOLE   74,199 0 0
Fate Therapeutics Inc Common Stock 31189P102 603,365 10,312,167 SH   SOLE   10,308,473 0 3,694
Grayscale Bitcoin Trust BTC Open-End Fund 389637109 270,951 7,910,978 SH   SOLE   7,224,708 670,381 15,889
Guardant Health Inc Common Stock 40131M109 8 82 SH   SOLE   82 0 0
HP Inc Common Stock 40434L105 21,896 581,264 SH   SOLE   581,264 0 0
Hexcel Corp Common Stock 428291108 388 7,489 SH   SOLE   7,489 0 0
Incyte Corp Common Stock 45337C102 120,815 1,645,985 SH   SOLE   1,645,985 0 0
Intellia Therapeutics Inc Common Stock 45826J105 936,092 7,916,882 SH   SOLE   6,809,880 805,490 301,512
Intercontinental Exchange Inc Common Stock 45866F104 34,260 250,494 SH   SOLE   250,494 0 0
Intuit Inc Common Stock 461202103 28,378 44,119 SH   SOLE   44,119 0 0
Intuitive Surgical Inc Common Stock 46120E602 27,136 75,525 SH   SOLE   75,525 0 0
OC Oerlikon Corp AG Common Stock H59187106 4,616 450,744 SH   SOLE   450,744 0 0
Invitae Corp Common Stock 46185L103 407,721 26,700,813 SH   SOLE   22,774,255 2,924,833 1,001,725
Ionis Pharmaceuticals Inc Common Stock 462222100 215,543 7,083,256 SH   SOLE   7,083,256 0 0
Iovance Biotherapeutics Inc Common Stock 462260100 137,477 7,201,518 SH   SOLE   7,043,744 0 157,774
Iridium Communications Inc Common Stock 46269C102 418,543 10,136,671 SH   SOLE   9,222,083 722,595 191,993
JD.com Inc ADR 47215P106 109,361 1,560,745 SH   SOLE   1,560,745 0 0
SGL Carbon SE Common Stock D6949M108 372 42,713 SH   SOLE   42,713 0 0
Kaiser Aluminum Corp Common Stock 483007704 4,037 42,973 SH   SOLE   42,973 0 0
Komatsu Ltd ADR 500458401 79,333 3,394,632 SH   SOLE   3,394,632 0 0
Kratos Defense & Security Solu Common Stock 50077B207 176,384 9,091,960 SH   SOLE   9,091,960 0 0
Henkel AG & Co KGaA Preference D3207M110 406 5,047 SH   SOLE   5,047 0 0
LendingClub Corp Common Stock 52603A208 47,007 1,944,040 SH   SOLE   1,841,786 0 102,254
Lincoln Electric Holdings Inc Common Stock 533900106 5,020 35,996 SH   SOLE   35,996 0 0
Siemens AG Common Stock D69671218 5,183 30,002 SH   SOLE   30,002 0 0
Materialise NV ADR 57667T100 146,296 6,128,880 SH   SOLE   5,807,312 116,023 205,545
MercadoLibre Inc Common Stock 58733R102 132,567 98,314 SH   SOLE   98,314 0 0
Microsoft Corp Common Stock 594918104 17,324 51,509 SH   SOLE   51,509 0 0
Bezeq The Israeli Telecommunic Common Stock M2012Q100 4,195 2,538,526 SH   SOLE   2,538,526 0 0
Moog Inc Common Stock 615394202 4,928 60,859 SH   SOLE   60,859 0 0
Danel Adir Yeoshua Ltd Common Stock M27013107 3,468 15,320 SH   SOLE   15,320 0 0
Hilan Ltd Common Stock M5299H123 3,775 56,303 SH   SOLE   56,303 0 0
Nano Dimension Ltd ADR 63008G203 75,531 19,876,620 SH   SOLE   19,876,620 0 0
NanoString Technologies Inc Common Stock 63009R109 0 0 SH   SOLE   0 0 0
Elbit Systems Ltd Common Stock M3760D101 48,769 280,073 SH   SOLE   280,073 0 0
Partner Communications Co Ltd Common Stock M78465107 5,621 689,569 SH   SOLE   689,569 0 0
Netflix Inc Common Stock 64110L106 13,959 23,170 SH   SOLE   23,170 0 0
Nice Ltd ADR 653656108 3,401 11,203 SH   SOLE   11,203 0 0
Matrix IT Ltd Common Stock M6859E153 3,581 117,904 SH   SOLE   117,904 0 0
Toray Industries Inc Common Stock J89494116 438 73,999 SH   SOLE   73,999 0 0
PTC Inc Common Stock 69370C100 15,361 126,797 SH   SOLE   126,797 0 0
Pacific Biosciences of Califor Common Stock 69404D108 539,798 26,383,103 SH   SOLE   24,547,126 1,409,647 426,330
One Software Technologies Ltd Common Stock M75260113 3,806 191,237 SH   SOLE   191,237 0 0
PayPal Holdings Inc Common Stock 70450Y103 41,015 217,493 SH   SOLE   217,493 0 0
Personalis Inc Common Stock 71535D106 69,753 4,888,115 SH   SOLE   4,888,115 0 0
Straumann Holding AG Common Stock H8300N119 17,561 8,290 SH   SOLE   8,290 0 0
Pinduoduo Inc ADR 722304102 29,821 511,509 SH   SOLE   511,509 0 0
Pinterest Inc Common Stock 72352L106 0 0 SH   SOLE   0 0 0
Pluristem Therapeutics Inc Common Stock 72940R300 1,565 1,071,878 SH   SOLE   1,071,878 0 0
Proto Labs Inc Common Stock 743713109 36,800 716,647 SH   SOLE   716,647 0 0
Roku Inc Common Stock 77543R102 1,376,862 6,033,578 SH   SOLE   5,399,784 482,274 151,520
Shopify Inc Common Stock 82509L107 985,151 715,230 SH   SOLE   652,182 49,035 14,013
Snap Inc Common Stock 83304A106 67,443 1,434,048 SH   SOLE   1,434,048 0 0
Splunk Inc Common Stock 848637104 101,858 880,213 SH   SOLE   880,213 0 0
Block Inc Common Stock 852234103 997,706 6,177,364 SH   SOLE   5,631,047 413,767 132,550
Teladoc Health Inc Common Stock 87918A105 1,737,436 18,922,198 SH   SOLE   17,518,720 1,057,448 346,030
Tencent Holdings Ltd ADR 88032Q109 26,586 456,022 SH   SOLE   456,022 0 0
Teradyne Inc Common Stock 880770102 75,951 464,446 SH   SOLE   464,446 0 0
Tesla Inc Common Stock 88160R101 2,036,579 1,927,155 SH   SOLE   1,778,678 146,831 1,646
Teva Pharmaceutical Industries ADR 881624209 2,441 304,792 SH   SOLE   304,792 0 0
3D Systems Corp Common Stock 88554D205 119,557 5,550,443 SH   SOLE   5,425,859 59,916 64,668
3M Co Common Stock 88579Y101 452 2,543 SH   SOLE   2,543 0 0
Trimble Inc Common Stock 896239100 417,806 4,791,901 SH   SOLE   4,645,307 80,908 65,686
Twilio Inc Common Stock 90138F102 1,068,953 4,059,214 SH   SOLE   3,682,665 292,501 84,048
Twist Bioscience Corp Common Stock 90184D100 291,544 3,767,203 SH   SOLE   3,623,175 77,492 66,536
2U Inc Common Stock 90214J101 179,616 8,949,466 SH   SOLE   7,664,955 869,517 414,994
United Parcel Service Inc Common Stock 911312106 5,503 25,672 SH   SOLE   25,672 0 0
Veracyte Inc Common Stock 92337F107 338,758 8,222,281 SH   SOLE   7,605,789 611,742 4,750
Workday Inc Common Stock 98138H101 55,709 203,929 SH   SOLE   203,929 0 0
Xerox Holdings Corp Common Stock 98421M106 509 22,461 SH   SOLE   22,461 0 0
Zillow Group Inc Common Stock 98954M200 65,650 1,028,195 SH   SOLE   1,028,195 0 0
Koninklijke DSM NV Common Stock N5017D122 494 2,191 SH   SOLE   2,191 0 0
Arkema SA Common Stock F0392W125 492 3,492 SH   SOLE   3,492 0 0
Sandvik AB Common Stock W74857165 521 18,671 SH   SOLE   18,671 0 0
Cellcom Israel Ltd Common Stock M2196U109 5,308 944,348 SH   SOLE   944,348 0 0
Evonik Industries AG Common Stock D2R90Y117 468 14,541 SH   SOLE   14,541 0 0
Fattal Holdings 1998 Ltd Common Stock M4148G105 3,023 29,923 SH   SOLE   29,923 0 0
SLM Solutions Group AG Common Stock D6T690109 14,965 778,905 SH   SOLE   778,905 0 0
Adyen NV Common Stock N3501V104 82,167 31,220 SH   SOLE   31,220 0 0
Sapiens International Corp NV Common Stock G7T16G103 3,126 90,753 SH   SOLE   90,753 0 0
CRISPR Therapeutics AG Common Stock H17182108 688,679 9,087,868 SH   SOLE   8,157,143 702,401 228,324
Spotify Technology SA Common Stock L8681T102 939,603 4,014,884 SH   SOLE   3,613,922 306,093 94,869
Allot Ltd Common Stock M0854Q105 2,448 206,051 SH   SOLE   206,051 0 0
AudioCodes Ltd Common Stock M15342104 2,981 85,813 SH   SOLE   85,813 0 0
Camtek Ltd/Israel Common Stock M20791105 3,619 78,613 SH   SOLE   78,613 0 0
Ceragon Networks Ltd Common Stock M22013102 2,333 904,394 SH   SOLE   904,394 0 0
Check Point Software Technolog Common Stock M22465104 2,942 25,242 SH   SOLE   25,242 0 0
Compugen Ltd Common Stock M25722105 39,656 9,222,415 SH   SOLE   8,879,327 210,870 132,218
CyberArk Software Ltd Common Stock M2682V108 2,979 17,192 SH   SOLE   17,192 0 0
Evogene Ltd Common Stock M4119S104 6,020 3,611,842 SH   SOLE   3,611,842 0 0
Fiverr International Ltd Common Stock M4R82T106 2,022 17,784 SH   SOLE   17,784 0 0
Ituran Location and Control Lt Common Stock M6158M104 3,110 116,612 SH   SOLE   116,612 0 0
Nova Ltd Common Stock M7516K103 4,430 30,242 SH   SOLE   30,242 0 0
Radware Ltd Common Stock M81873107 3,865 92,824 SH   SOLE   92,824 0 0
Stratasys Ltd Common Stock M85548101 187,469 7,654,932 SH   SOLE   6,250,970 807,802 596,160
Taro Pharmaceutical Industries Common Stock M8737E108 2,468 49,259 SH   SOLE   49,259 0 0
Tower Semiconductor Ltd Common Stock M87915274 3,910 98,534 SH   SOLE   98,534 0 0
UroGen Pharma Ltd Common Stock M96088105 1,774 186,493 SH   SOLE   186,493 0 0
Wix.com Ltd Common Stock M98068105 2,467 15,633 SH   SOLE   15,633 0 0
DocuSign Inc Common Stock 256163106 385,543 2,531,306 SH   SOLE   2,300,930 182,682 47,694
Discovery Ltd Common Stock S2192Y109 55,647 6,175,551 SH   SOLE   6,175,551 0 0
Inmode Ltd Common Stock M5425M103 2,573 36,457 SH   SOLE   36,457 0 0
Perion Network Ltd Common Stock M78673114 3,379 140,516 SH   SOLE   140,516 0 0
Silvergate Capital Corp Common Stock 82837P408 60,689 409,509 SH   SOLE   409,509 0 0
Z Holdings Corp Common Stock J9894K105 27,364 4,722,484 SH   SOLE   4,722,484 0 0
Sea Ltd ADR 81141R100 146,493 654,834 SH   SOLE   654,834 0 0
Z Holdings Corp ADR 98877X101 141 12,232 SH   SOLE   12,232 0 0
Synopsys Inc Common Stock 871607107 34,531 93,708 SH   SOLE   93,708 0 0
RADA Electronic Industries Ltd Common Stock M81863124 2,753 292,211 SH   SOLE   292,211 0 0
PagerDuty Inc Common Stock 69553P100 348,227 10,020,916 SH   SOLE   8,767,550 932,948 320,418
Caterpillar Inc Common Stock 149123101 29,812 144,201 SH   SOLE   144,201 0 0
Arconic Corp Common Stock 03966V107 5,165 156,454 SH   SOLE   156,454 0 0
Adaptive Biotechnologies Corp Common Stock 00650F109 159,882 5,697,868 SH   SOLE   5,697,868 0 0
10X Genomics Inc Common Stock 88025U109 396,363 2,660,866 SH   SOLE   2,367,165 249,918 43,783
Bitcoin Fund/The Closed-End Fund 09175G104 7,815 161,902 SH   SOLE   0 0 161,902
Schrodinger Inc/United States Common Stock 80810D103 102,331 2,938,022 SH   SOLE   2,938,022 0 0
TCS Group Holding PLC GDR 87238U203 57,613 683,268 SH   SOLE   683,268 0 0
Adyen NV ADR 00783V104 36,273 1,378,166 SH   SOLE   1,378,166 0 0
Cie Generale des Etablissement Common Stock F61824144 5,271 32,113 SH   SOLE   32,113 0 0
voestalpine AG Common Stock A9101Y103 438 12,089 SH   SOLE   12,089 0 0
Yeahka Ltd Common Stock G9835C108 70 21,200 SH   SOLE   21,200 0 0
Accolade Inc Common Stock 00437E102 132,568 5,029,148 SH   SOLE   5,029,148 0 0
Berkeley Lights Inc Common Stock 084310101 145,557 8,006,435 SH   SOLE   8,006,435 0 0
Vertex Pharmaceuticals Inc Common Stock 92532F100 203,963 928,791 SH   SOLE   928,791 0 0
BYD Co Ltd ADR 05606L100 20,866 309,126 SH   SOLE   309,126 0 0
Kamada Ltd Common Stock M6240T109 3,838 580,877 SH   SOLE   580,877 0 0
BATM Advanced Communications L Common Stock M19199112 2,890 2,703,636 SH   SOLE   2,703,636 0 0
Gamida Cell Ltd Common Stock M47364100 1,908 751,069 SH   SOLE   751,069 0 0
Gilat Satellite Networks Ltd Common Stock M51474118 2,531 358,058 SH   SOLE   358,058 0 0
PolyPid Ltd Common Stock M8001Q118 2,334 406,568 SH   SOLE   406,568 0 0
Silicom Ltd Common Stock M84116108 3,814 73,919 SH   SOLE   73,919 0 0
Organovo Holdings Inc Common Stock 68620A203 1,198 330,157 SH   SOLE   326,721 3,436 0
Surface Oncology Inc Common Stock 86877M209 25,459 5,326,127 SH   SOLE   5,326,127 0 0
Takeda Pharmaceutical Co Ltd ADR 874060205 107,164 7,862,379 SH   SOLE   7,862,379 0 0
Niu Technologies ADR 65481N100 51,524 3,198,249 SH   SOLE   3,198,249 0 0
Thermo Fisher Scientific Inc Common Stock 883556102 759 1,138 SH   SOLE   1,138 0 0
Exact Sciences Corp Common Stock 30063P105 1,050,395 13,496,014 SH   SOLE   12,297,889 922,300 275,825
Snowflake Inc Common Stock 833445109 224 662 SH   SOLE   662 0 0
Unity Software Inc Common Stock 91332U101 1,109,339 7,758,155 SH   SOLE   6,964,657 592,683 200,815
Beam Therapeutics Inc Common Stock 07373V105 636,197 7,983,401 SH   SOLE   7,983,401 0 0
Regeneron Pharmaceuticals Inc Common Stock 75886F107 46,097 72,993 SH   SOLE   72,993 0 0
Repare Therapeutics Inc Common Stock 760273102 62,866 2,980,836 SH   SOLE   2,980,836 0 0
Cloudflare Inc Common Stock 18915M107 16,378 124,549 SH   SOLE   124,549 0 0
Palantir Technologies Inc Common Stock 69608A108 642,511 35,283,396 SH   SOLE   32,059,533 2,467,063 756,800
Zoom Video Communications Inc Common Stock 98980L101 1,268,157 6,895,530 SH   SOLE   6,224,171 518,811 152,548
Honeywell International Inc Common Stock 438516106 5,397 25,883 SH   SOLE   25,883 0 0
Alphabet Inc Common Stock 02079K305 3 1 SH   SOLE   1 0 0
Roche Holding AG ADR 771195104 54 1,036 SH   SOLE   1,036 0 0
Opendoor Technologies Inc Common Stock 683712103 23,739 1,624,870 SH   SOLE   1,624,870 0 0
Kaspi.KZ JSC GDR 48581R205 25,651 221,126 SH   SOLE   221,126 0 0
908 Devices Inc Common Stock 65443P102 77,517 2,996,393 SH   SOLE   2,996,393 0 0
Magna International Inc Common Stock 559222401 49,898 616,482 SH   SOLE   616,482 0 0
Peloton Interactive Inc Common Stock 70614W100 365 10,196 SH   SOLE   10,196 0 0
Veeva Systems Inc Common Stock 922475108 53,990 211,328 SH   SOLE   211,328 0 0
Grayscale Ethereum Trust Open-End Fund 389638107 22,104 683,077 SH   SOLE   5,009 678,068 0
SPDR S&P 500 ETF Trust ETP 78462F103 15 31 SH   SOLE   31 0 0
1Life Healthcare Inc Common Stock 68269G107 83,381 4,745,669 SH   SOLE   4,745,669 0 0
PyroGenesis Canada Inc Common Stock 74734T104 301 114,238 SH   SOLE   114,238 0 0
Arad Ltd Common Stock M1492B104 3,443 216,747 SH   SOLE   216,747 0 0
Augwind Energy Tech Storage Lt Common Stock M6058P108 3,114 199,698 SH   SOLE   199,698 0 0
Bet Shemesh Engines Holdings 1 Common Stock M20119109 2,738 124,940 SH   SOLE   124,940 0 0
Electra Consumer Products 1970 Common Stock M3798N105 3,686 63,682 SH   SOLE   63,682 0 0
E&M Computing Ltd Common Stock M4026X105 3,949 477,304 SH   SOLE   477,304 0 0
Intercure Ltd Common Stock M549GJ111 2 257 SH   SOLE   257 0 0
Magic Software Enterprises Ltd Common Stock 559166103 3,137 147,818 SH   SOLE   147,818 0 0
Malam - Team Ltd Common Stock M87437105 3,385 92,765 SH   SOLE   92,765 0 0
Plasson Industries Ltd Common Stock M7933B108 3,178 44,968 SH   SOLE   44,968 0 0
Desktop Metal Inc Common Stock 25058X105 22,676 4,581,100 SH   SOLE   4,581,100 0 0
Enlivex Therapeutics Ltd Common Stock M4130Y106 2,183 349,308 SH   SOLE   349,308 0 0
JFrog Ltd Common Stock M6191J100 2,540 85,514 SH   SOLE   85,514 0 0
Eastman Kodak Co Common Stock 277461406 297 63,390 SH   SOLE   63,390 0 0
Kornit Digital Ltd Common Stock M6372Q113 3,093 20,313 SH   SOLE   20,313 0 0
Lockheed Martin Corp Common Stock 539830109 37,274 104,876 SH   SOLE   104,876 0 0
Nano-X Imaging Ltd Common Stock M70700105 1,889 129,903 SH   SOLE   129,903 0 0
SolarEdge Technologies Inc Common Stock 83417M104 2,820 10,051 SH   SOLE   10,051 0 0
Skillz Inc Common Stock 83067L109 179,225 24,089,428 SH   SOLE   22,806,446 739,469 543,513
Teledyne Technologies Inc Common Stock 879360105 32,176 73,648 SH   SOLE   73,648 0 0
Twitter Inc Common Stock 90184L102 745,362 17,245,755 SH   SOLE   15,633,099 1,254,308 358,348
Butterfly Network Inc Common Stock 124155102 50,954 7,616,514 SH   SOLE   7,616,514 0 0
Signify Health Inc Common Stock 82671G100 284,547 20,010,328 SH   SOLE   19,118,350 536,466 355,512
ARK Innovation ETF ETP 00214Q104 15,039 158,992 SH   SOLE   158,992 0 0
Bill.com Holdings Inc Common Stock 090043100 40,943 164,329 SH   SOLE   164,329 0 0
DraftKings Inc Common Stock 26142R104 576,775 20,996,534 SH   SOLE   19,120,786 1,468,498 407,250
Vuzix Corp Common Stock 92921W300 62,777 7,240,700 SH   SOLE   7,240,700 0 0
iShares Russell 1000 Growth ET ETP 464287614 1,125 3,681 SH   SOLE   3,681 0 0
Airbus SE Common Stock N0280G100 5,008 39,148 SH   SOLE   39,148 0 0
Thales SA Common Stock F9156M108 4,826 56,668 SH   SOLE   56,668 0 0
Komatsu Ltd Common Stock J35759125 21,598 923,588 SH   SOLE   923,588 0 0
Boeing Co/The Common Stock 097023105 0 0 SH   SOLE   0 0 0
Garmin Ltd Common Stock H2906T109 11,286 82,884 SH   SOLE   82,884 0 0
HEICO Corp Common Stock 422806109 5,507 38,188 SH   SOLE   38,188 0 0
L3Harris Technologies Inc Common Stock 502431109 24,499 114,889 SH   SOLE   114,889 0 0
The 3D Printing ETF ETP 00214Q500 36,341 1,059,507 SH   SOLE   1,059,507 0 0
ROBLOX Corp Common Stock 771049103 208,795 2,023,993 SH   SOLE   1,969,900 32,547 21,546
Spirit AeroSystems Holdings In Common Stock 848574109 8,732 202,648 SH   SOLE   202,648 0 0
UiPath Inc Common Stock 90364P105 1,160,324 26,902,940 SH   SOLE   25,030,373 1,411,471 461,096
Coinbase Global Inc Common Stock 19260Q107 1,376,302 5,453,508 SH   SOLE   4,940,467 396,331 116,710
TuSimple Holdings Inc Common Stock 90089L108 353,969 9,873,614 SH   SOLE   8,685,284 969,259 219,071
Recursion Pharmaceuticals Inc Common Stock 75629V104 38,234 2,232,013 SH   SOLE   2,232,013 0 0
Zymergen Inc Common Stock 98985X100 21,759 3,252,396 SH   SOLE   3,252,396 0 0
Okta Inc Common Stock 679295105 43,882 195,755 SH   SOLE   195,755 0 0
Blade Air Mobility Inc Common Stock 092667104 70,124 7,941,557 SH   SOLE   7,941,557 0 0
JD Logistics Inc Common Stock G5074S101 18,754 5,528,713 SH   SOLE   5,528,713 0 0
Hexagon AB Common Stock W4R431112 5,219 329,018 SH   SOLE   329,018 0 0
StoneCo Ltd Common Stock G85158106 46,794 2,775,435 SH   SOLE   2,775,435 0 0
Dynamics Special Purpose Corp Common Stock 268010105 23,296 2,362,677 SH   SOLE   2,362,677 0 0
Walt Disney Co/The Common Stock 254687106 40,909 264,117 SH   SOLE   264,117 0 0
Quantum-Si Inc Common Stock 74765K105 102,838 13,067,150 SH   SOLE   13,067,150 0 0
Verve Therapeutics Inc Common Stock 92539P101 51,601 1,399,545 SH   SOLE   1,399,545 0 0
Etsy Inc Common Stock 29786A106 114,510 523,020 SH   SOLE   523,020 0 0
Markforged Holding Corp Common Stock 57064N102 60,049 11,182,279 SH   SOLE   11,182,279 0 0
Dassault Systemes SE Common Stock F24571451 33,581 563,822 SH   SOLE   563,822 0 0
Conformis Inc Common Stock 20717E101 9,656 12,681,400 SH   SOLE   12,681,400 0 0
Exco Technologies Ltd Common Stock 30150P109 4,998 613,249 SH   SOLE   613,249 0 0
Xometry Inc Common Stock 98423F109 13,866 270,553 SH   SOLE   270,553 0 0
5N Plus Inc Common Stock 33833X101 382 202,898 SH   SOLE   202,898 0 0
BICO Group AB Common Stock W2R45B104 8,840 288,195 SH   SOLE   288,195 0 0
Farfetch Ltd Common Stock 30744W107 25,532 763,733 SH   SOLE   763,733 0 0
Robinhood Markets Inc Common Stock 770700102 423,539 23,847,924 SH   SOLE   21,533,624 1,829,117 485,183
Concord Acquisition Corp Common Stock 206071102 32,994 3,172,501 SH   SOLE   3,172,501 0 0
BioLine RX Ltd ADR 09071M205 2,162 1,059,722 SH   SOLE   1,059,722 0 0
Chemomab Therapeutics Ltd ADR 16385C104 1,844 267,292 SH   SOLE   267,292 0 0
Priortech Ltd Common Stock M8164J109 3,754 98,682 SH   SOLE   98,682 0 0
Playtika Holding Corp Common Stock 72815L107 1,867 108,001 SH   SOLE   108,001 0 0
Purple Biotech Ltd ADR 74638P109 2,577 662,499 SH   SOLE   662,499 0 0
Abra Information Technologies Common Stock M0R53V104 3,262 2,448,448 SH   SOLE   2,448,448 0 0
Icecure Medical Ltd Common Stock M53071136 1,401 464,893 SH   SOLE   464,893 0 0
Nayax Ltd Common Stock M7S750100 3,154 877,413 SH   SOLE   877,413 0 0
Phinergy Ltd Common Stock M7S8CD102 2,397 904,524 SH   SOLE   904,524 0 0
Aquarius Engines AM Ltd Common Stock M1R50V113 2,687 248,571 SH   SOLE   248,571 0 0
Check Cap Ltd Common Stock M2361E203 2,198 3,257,788 SH   SOLE   3,257,788 0 0
Cognyte Software Ltd Common Stock M25133105 2,225 142,013 SH   SOLE   142,013 0 0
Collplant Biotechnologies Ltd Common Stock M2R51X116 2,707 165,454 SH   SOLE   165,454 0 0
Entera Bio Ltd Common Stock M40527109 1,945 690,922 SH   SOLE   690,922 0 0
Innoviz Technologies Ltd Common Stock M5R635108 3,883 612,508 SH   SOLE   612,508 0 0
MediWound Ltd Common Stock M68830104 1,969 834,166 SH   SOLE   834,166 0 0
Monday.com Ltd Common Stock M7S64H106 23,749 76,927 SH   SOLE   76,927 0 0
SimilarWeb Ltd Common Stock M84137104 2,738 152,868 SH   SOLE   152,868 0 0
Tufin Software Technologies Lt Common Stock M8893U102 3,351 317,670 SH   SOLE   317,670 0 0
Vascular Biogenics Ltd Common Stock M96883109 2,621 1,330,206 SH   SOLE   1,330,206 0 0
WalkMe Ltd Common Stock M97628107 2,477 126,192 SH   SOLE   126,192 0 0
Joby Aviation Inc Common Stock G65163100 7,237 991,389 SH   SOLE   991,389 0 0
General Electric Co Common Stock 369604301 4,514 47,780 SH   SOLE   47,780 0 0
Pfizer Inc Common Stock 717081103 55,734 943,849 SH   SOLE   943,849 0 0
LivePerson Inc Common Stock 538146101 11 302 SH   SOLE   302 0 0
Genius Sports Ltd Common Stock G3934V109 40,157 5,283,809 SH   SOLE   5,283,809 0 0
Vanguard Growth ETF ETP 922908736 898 2,797 SH   SOLE   2,797 0 0
ARK Genomic Revolution ETF ETP 00214Q302 3,270 53,390 SH   SOLE   53,390 0 0
Ginkgo Bioworks Holdings Inc Common Stock 37611X100 358,833 43,180,820 SH   SOLE   41,226,977 1,181,150 772,693
SomaLogic Inc Common Stock 83444K105 102,802 8,831,819 SH   SOLE   8,831,819 0 0
SomaLogic Inc Equity WRT 83444K113 1,002 300,000 SH Call SOLE   300,000 0 0
Archer Aviation Inc Common Stock 03945R102 68,288 11,306,020 SH   SOLE   11,306,020 0 0
Toast Inc Common Stock 888787108 37,925 1,092,620 SH   SOLE   1,092,620 0 0
Velo3D Inc Common Stock 92259N104 49,144 6,292,430 SH   SOLE   6,292,430 0 0
Pagseguro Digital Ltd Common Stock G68707101 0 0 SH   SOLE   0 0 0
Mynaric AG ADR 62857X101 5,004 393,413 SH   SOLE   393,413 0 0
Allogene Therapeutics Inc Common Stock 019770106 0 0 SH   SOLE   0 0 0
Burning Rock Biotech Ltd ADR 12233L107 8,077 847,539 SH   SOLE   847,539 0 0
Nextdoor Holdings Inc Common Stock 65345M108 44,342 5,619,996 SH   SOLE   5,619,996 0 0
Abcam PLC ADR 000380204 195 8,298 SH   SOLE   8,298 0 0
Acushnet Holdings Corp Common Stock 005098108 195 3,668 SH   SOLE   3,668 0 0
Adobe Inc Common Stock 00724F101 196 345 SH   SOLE   345 0 0
Agora Inc ADR 00851L103 190 11,723 SH   SOLE   11,723 0 0
Apple Inc Common Stock 037833100 196 1,104 SH   SOLE   1,104 0 0
Autoliv Inc Common Stock 052800109 196 1,897 SH   SOLE   1,897 0 0
Axon Enterprise Inc Common Stock 05464C101 198 1,261 SH   SOLE   1,261 0 0
Best Buy Co Inc Common Stock 086516101 195 1,921 SH   SOLE   1,921 0 0
Beyond Meat Inc Common Stock 08862E109 193 2,962 SH   SOLE   2,962 0 0
Bio-Techne Corp Common Stock 09073M104 195 376 SH   SOLE   376 0 0
Brady Corp Common Stock 104674106 196 3,635 SH   SOLE   3,635 0 0
Bruker Corp Common Stock 116794108 195 2,319 SH   SOLE   2,319 0 0
Buckle Inc/The Common Stock 118440106 197 4,651 SH   SOLE   4,651 0 0
Cboe Global Markets Inc Common Stock 12503M108 196 1,505 SH   SOLE   1,505 0 0
CDW Corp/DE Common Stock 12514G108 196 957 SH   SOLE   957 0 0
CRH PLC ADR 12626K203 196 3,720 SH   SOLE   3,720 0 0
Canada Goose Holdings Inc Common Stock 135086106 195 5,263 SH   SOLE   5,263 0 0
Canadian Solar Inc Common Stock 136635109 193 6,183 SH   SOLE   6,183 0 0
Cardlytics Inc Common Stock 14161W105 191 2,888 SH   SOLE   2,888 0 0
ChargePoint Holdings Inc Common Stock 15961R105 195 10,232 SH   SOLE   10,232 0 0
Corsair Gaming Inc Common Stock 22041X102 194 9,241 SH   SOLE   9,241 0 0
Crowdstrike Holdings Inc Common Stock 22788C105 194 949 SH   SOLE   949 0 0
Datadog Inc Common Stock 23804L103 196 1,099 SH   SOLE   1,099 0 0
DigitalOcean Holdings Inc Common Stock 25402D102 192 2,396 SH   SOLE   2,396 0 0
Dropbox Inc Common Stock 26210C104 195 7,948 SH   SOLE   7,948 0 0
Dynatrace Inc Common Stock 268150109 194 3,216 SH   SOLE   3,216 0 0
Five9 Inc Common Stock 338307101 196 1,428 SH   SOLE   1,428 0 0
Gitlab Inc Common Stock 37637K108 199 2,292 SH   SOLE   2,292 0 0
Hasbro Inc Common Stock 418056107 196 1,928 SH   SOLE   1,928 0 0
Hibbett Inc Common Stock 428567101 196 2,723 SH   SOLE   2,723 0 0
HubSpot Inc Common Stock 443573100 194 294 SH   SOLE   294 0 0
iRobot Corp Common Stock 462726100 194 2,947 SH   SOLE   2,947 0 0
Knowles Corp Common Stock 49926D109 196 8,381 SH   SOLE   8,381 0 0
Lemonade Inc Common Stock 52567D107 194 4,611 SH   SOLE   4,611 0 0
Lululemon Athletica Inc Common Stock 550021109 195 499 SH   SOLE   499 0 0
Steven Madden Ltd Common Stock 556269108 197 4,244 SH   SOLE   4,244 0 0
MaxLinear Inc Common Stock 57776J100 196 2,604 SH   SOLE   2,604 0 0
McCormick & Co Inc/MD Common Stock 579780206 197 2,036 SH   SOLE   2,036 0 0
Momentive Global Inc Common Stock 60878Y108 193 9,140 SH   SOLE   9,140 0 0
Natura & Co Holding SA ADR 63884N108 196 21,090 SH   SOLE   21,090 0 0
NetApp Inc Common Stock 64110D104 196 2,133 SH   SOLE   2,133 0 0
Nutanix Inc Common Stock 67059N108 195 6,136 SH   SOLE   6,136 0 0
NVIDIA Corp Common Stock 67066G104 196 665 SH   SOLE   665 0 0
Omnicell Inc Common Stock 68213N109 196 1,086 SH   SOLE   1,086 0 0
PVH Corp Common Stock 693656100 196 1,841 SH   SOLE   1,841 0 0
Pearson PLC ADR 705015105 196 23,348 SH   SOLE   23,348 0 0
Qualys Inc Common Stock 74758T303 194 1,413 SH   SOLE   1,413 0 0
Rapid7 Inc Common Stock 753422104 196 1,663 SH   SOLE   1,663 0 0
Roper Technologies Inc Common Stock 776696106 196 398 SH   SOLE   398 0 0
salesforce.com Inc Common Stock 79466L302 195 768 SH   SOLE   768 0 0
Skyworks Solutions Inc Common Stock 83088M102 195 1,257 SH   SOLE   1,257 0 0
Sonoco Products Co Common Stock 835495102 196 3,385 SH   SOLE   3,385 0 0
Sony Group Corp ADR 835699307 196 1,551 SH   SOLE   1,551 0 0
Sonos Inc Common Stock 83570H108 196 6,586 SH   SOLE   6,586 0 0
Spectrum Brands Holdings Inc Common Stock 84790A105 198 1,942 SH   SOLE   1,942 0 0
Sprout Social Inc Common Stock 85209W109 193 2,132 SH   SOLE   2,132 0 0
Starbucks Corp Common Stock 855244109 196 1,673 SH   SOLE   1,673 0 0
Steelcase Inc Common Stock 858155203 196 16,694 SH   SOLE   16,694 0 0
Stitch Fix Inc Common Stock 860897107 194 10,230 SH   SOLE   10,230 0 0
TPI Composites Inc Common Stock 87266J104 194 12,936 SH   SOLE   12,936 0 0
TripAdvisor Inc Common Stock 896945201 195 7,144 SH   SOLE   7,144 0 0
VF Corp Common Stock 918204108 196 2,677 SH   SOLE   2,677 0 0
Warby Parker Inc Common Stock 93403J106 194 4,173 SH   SOLE   4,173 0 0
Atlassian Corp PLC Common Stock G06242104 194 509 SH   SOLE   509 0 0
Globant SA Common Stock L44385109 195 621 SH   SOLE   621 0 0
ASML Holding NV NY Reg Shrs N07059210 196 246 SH   SOLE   246 0 0
Elastic NV Common Stock N14506104 194 1,578 SH   SOLE   1,578 0 0
NU Holdings Ltd/Cayman Islands Common Stock G6683N103 36,849 3,928,467 SH   SOLE   3,928,467 0 0
Nurix Therapeutics Inc Common Stock 67080M103 1,272 43,947 SH   SOLE   43,947 0 0
XPeng Inc ADR 98422D105 34,717 689,791 SH   SOLE   689,791 0 0
Endeavor Group Holdings Inc Common Stock 29260Y109 15,453 442,910 SH   SOLE   442,910 0 0
Hyperfine Inc Common Stock 44916K106 7,250 1,000,000 SH   SOLE   1,000,000 0 0
ARK Innovation ETF ETP 00214Q104 795 8,400 SH Call SOLE   8,400 0 0
Coinbase Global Inc Common Stock 19260Q107 505 2,000 SH Call SOLE   2,000 0 0
CRISPR Therapeutics AG Common Stock H17182108 99 1,300 SH Call SOLE   1,300 0 0
DraftKings Inc Common Stock 26142R104 233 8,500 SH Call SOLE   8,500 0 0
Intel Corp Common Stock 458140100 263 5,100 SH Put SOLE   5,100 0 0
SPDR S&P Regional Banking ETF ETP 78464A698 524 7,400 SH Put SOLE   7,400 0 0
Pacific Biosciences of Califor Common Stock 69404D108 360 17,600 SH Call SOLE   17,600 0 0
Roku Inc Common Stock 77543R102 160 700 SH Call SOLE   700 0 0
Block Inc Common Stock 852234103 242 1,500 SH Call SOLE   1,500 0 0
Tesla Inc Common Stock 88160R101 423 400 SH Call SOLE   400 0 0
Energy Select Sector SPDR Fund ETP 81369Y506 1,798 32,400 SH Put SOLE   32,400 0 0
Zoom Video Communications Inc Common Stock 98980L101 1,582 8,600 SH Call SOLE   8,600 0 0