The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACLARIS THERAPEUTICS INC COM 00461U105 3,120 173,327 SH   SOLE   173,327 0 0
ADAGIO THERAPEUTICS INC COM 00534A102 211 5,000 SH   SOLE   5,000 0 0
ADAMAS PHARMACEUTICALS INC COM 00548A106 1,414 288,042 SH   SOLE   288,042 0 0
AFFIMED N V COM N01045108 292 47,182 SH   SOLE   47,182 0 0
AMRYT PHARMA PLC SPONSORED ADS 03217L106 6,218 516,221 SH   SOLE   516,221 0 0
ARCTURUS THERAPEUTICS HLDGS COM 03969T109 297 6,208 SH   SOLE   6,208 0 0
ARENA PHARMACEUTICALS INC COM NEW 040047607 1,106 18,581 SH   SOLE   18,581 0 0
ARVINAS INC COM 04335A105 3,061 37,249 SH   SOLE   37,249 0 0
ATHIRA PHARMA INC COM 04746L104 998 106,388 SH   SOLE   106,388 0 0
AYALA PHARMACEUTICALS INC COM 05465V108 464 40,956 SH   SOLE   40,956 0 0
BELLUS HEALTH INC NEW COM NEW 07987C204 2,241 365,000 SH   SOLE   365,000 0 0
BENITEC BIOPHARMA INC COM 08205P100 1,778 498,009 SH   SOLE   498,009 0 0
BIOGEN INC COM 09062X103 1,242 4,389 SH   SOLE   4,389 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 8,598 61,897 SH   SOLE   61,897 0 0
CABALETTA BIO INC COM 12674W109 511 42,022 SH   SOLE   42,022 0 0
CALITHERA BIOSCIENCES INC COM 13089P101 406 186,245 SH   SOLE   186,245 0 0
CATALYST BIOSCIENCES INC COM NEW 14888D208 41 10,000 SH   SOLE   10,000 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 2,065 38,243 SH   SOLE   38,243 0 0
CERUS CORP COM 157085101 3,772 619,369 SH   SOLE   619,369 0 0
CHEMOCENTRYX INC COM 16383L106 2,380 139,200 SH Put SOLE   139,200 0 0
COGENT BIOSCIENCES INC COM 19240Q201 5,701 677,900 SH   SOLE   677,900 0 0
COMPUGEN LTD ORD M25722105 1,215 203,532 SH   SOLE   203,532 0 0
COMPUGEN LTD ORD M25722105 1,481 248,000 SH Call SOLE   248,000 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107 1,039 49,382 SH   SOLE   49,382 0 0
CURIS INC COM NEW 231269200 486 62,070 SH   SOLE   62,070 0 0
CYBIN INC COM 23256X100 549 250,000 SH   SOLE   250,000 0 0
CYCLACEL PHARMACEUTICALS INC COM 23254L603 2,048 388,632 SH   SOLE   388,632 0 0
CYTOKINETICS INC COM NEW 23282W605 1,762 49,309 SH   SOLE   49,309 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 1,266 37,249 SH   SOLE   37,249 0 0
DICERNA PHARMACEUTICALS INC COM 253031108 626 31,040 SH   SOLE   31,040 0 0
ELOXX PHARMACEUTICALS INC COM 29014R103 2,054 1,259,840 SH   SOLE   1,259,840 0 0
ERASCA INC COM 29479A108 1,976 93,122 SH   SOLE   93,122 0 0
EVELO BIOSCIENCES INC COM 299734103 434 61,700 SH Put SOLE   61,700 0 0
EVOGENE LTD SHS M4119S104 656 248,327 SH   SOLE   248,327 0 0
EYEPOINT PHARMACEUTICALS INC COM NEW 30233G209 1,347 129,290 SH   SOLE   129,290 0 0
FULCRUM THERAPEUTICS INC COM 359616109 5,238 185,691 SH   SOLE   185,691 0 0
GUARDANT HEALTH INC COM 40131M109 527 4,218 SH   SOLE   4,218 0 0
HALOZYME THERAPEUTICS INC COM 40637H109 2,448 60,170 SH   SOLE   60,170 0 0
HELIX ACQUISITION CORP COM CL A G4444C102 2,224 223,906 SH   SOLE   223,906 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 5,747 52,469 SH   SOLE   52,469 0 0
IMMATICS N.V SHS N44445109 5,692 437,866 SH   SOLE   437,866 0 0
IMMUNOGEN INC COM 45253H101 3,685 649,919 SH   SOLE   649,919 0 0
INSMED INC COM PAR $.01 457669307 4,808 174,588 SH   SOLE   174,588 0 0
INTELLIA THERAPEUTICS INC COM 45826J105 664 4,950 SH   SOLE   4,950 0 0
INTRA-CELLULAR THERAPIES INC COM 46116X101 3,798 101,890 SH   SOLE   101,890 0 0
ITEOS THERAPEUTICS INC COM 46565G104 3,157 116,931 SH   SOLE   116,931 0 0
IVERIC BIO INC COM 46583P102 487 30,000 SH   SOLE   30,000 0 0
JOUNCE THERAPEUTICS INC COM 481116101 1,550 208,559 SH   SOLE   208,559 0 0
KEROS THERAPEUTICS INC COM 492327101 396 10,000 SH   SOLE   10,000 0 0
KURA ONCOLOGY INC COM 50127T109 1,060 56,614 SH   SOLE   56,614 0 0
LEAP THERAPEUTICS INC COM 52187K101 2,486 620,000 SH   SOLE   620,000 0 0
LUCIRA HEALTH INC COM 54948U105 1,678 220,758 SH   SOLE   220,758 0 0
MEDICUS SCIENCES ACQUISITION *W EXP 02/12/202 G5960S124 35 49,990 SH   SOLE   49,990 0 0
MEDICUS SCIENCES ACQUISITION CL A SHS G5960S108 1,073 110,040 SH   SOLE   110,040 0 0
MEREO BIOPHARMA GROUP PLC ADS 589492107 885 365,661 SH   SOLE   365,661 0 0
MERUS N V COM N5749R100 7,611 345,964 SH   SOLE   345,964 0 0
MIRATI THERAPEUTICS INC COM 60468T105 8,127 45,941 SH   SOLE   45,941 0 0
MORPHIC HLDG INC COM 61775R105 3,268 57,704 SH   SOLE   57,704 0 0
NEXTCURE INC COM 65343E108 4,862 721,302 SH   SOLE   721,302 0 0
OTONOMY INC COM 68906L105 1,953 1,017,048 SH   SOLE   1,017,048 0 0
POINT BIOPHARMA GLOBAL INC COM 730541109 552 71,729 SH   SOLE   71,729 0 0
POLYPID LTD SHS M8001Q118 1,426 183,230 SH   SOLE   183,230 0 0
RAPT THERAPEUTICS INC COM 75382E109 366 11,796 SH   SOLE   11,796 0 0
RENALYTIX PLC ADS 75973T101 742 37,000 SH   SOLE   37,000 0 0
RENOVACOR INC *W EXP 99/99/999 75989E114 42 104,828 SH   SOLE   104,828 0 0
RESEARCH ALLIANCE CORP II COM CL A 760873109 4,663 473,396 SH   SOLE   473,396 0 0
SEAGEN INC COM 81181C104 1,995 11,749 SH   SOLE   11,749 0 0
SERES THERAPEUTICS INC COM 81750R102 1,913 274,833 SH   SOLE   274,833 0 0
SIERRA ONCOLOGY INC COM NEW 82640U404 3,584 163,486 SH   SOLE   163,486 0 0
SOCIAL CAP SUVRETTA HLD CRPI CLASS A ORD SHS G8253W109 1,039 106,000 SH   SOLE   106,000 0 0
SOCIAL CAP SUVRETTA HLDS CP CLASS A ORD SHS G8253Y105 1,040 106,000 SH   SOLE   106,000 0 0
SOCIAL CAP SUVRETTA HLDS CRP CLASS A ORD SHS G8253T106 1,055 106,000 SH   SOLE   106,000 0 0
SOCIAL CAP SUVRETTA HLDS CRP CLASS A ORD SHS G8253U103 1,047 106,000 SH   SOLE   106,000 0 0
STEREOTAXIS INC COM NEW 85916J409 1,569 291,696 SH   SOLE   291,696 0 0
SURFACE ONCOLOGY INC COM 86877M209 379 50,000 SH   SOLE   50,000 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102 3,911 21,189 SH   SOLE   21,189 0 0
VERACYTE INC COM 92337F107 8,340 179,548 SH   SOLE   179,548 0 0
VIEWRAY INC COM 92672L107 1,334 185,035 SH   SOLE   185,035 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104 1,745 106,078 SH   SOLE   106,078 0 0
VISTAGEN THERAPEUTICS INC COM NEW 92840H202 1,939 707,733 SH   SOLE   707,733 0 0
XENON PHARMACEUTICALS INC COM 98420N105 297 19,432 SH   SOLE   19,432 0 0
ZENTALIS PHARMACEUTICALS INC COM 98943L107 1,590 23,855 SH   SOLE   23,855 0 0