The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
89BIO INC COM 282559103 2,481 126,652 SH   SOLE 126,652 0 0
ACCURAY INC COM 004397105 3,720 941,800 SH   SOLE 941,800 0 0
ADICET BIO INC COM 007002108 2,950 376,281 SH   SOLE 376,281 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 3,295 289,040 SH   SOLE 289,040 0 0
AERIE PHARMACEUTICALS INC NOTE 1.500%10/0 00771VAB4 1,375 1,500,000 PRN   SOLE 1,500,000 0 0
AFFIMED N V COM N01045108 5,963 964,857 SH   SOLE 964,857 0 0
ALECTOR INC COM 014442107 2,451 107,412 SH   SOLE 107,412 0 0
ALPINE IMMUNE SCIENCES INC COM 02083G100 1,190 111,501 SH   SOLE 111,501 0 0
ANNEXON INC COM 03589W102 434 23,296 SH   SOLE 23,296 0 0
ARCUS BIOSCIENCES INC COM 03969F109 4,313 123,700 SH   SOLE 123,700 0 0
ARENA PHARMACEUTICALS INC COM NEW 040047607 7,123 119,615 SH   SOLE 119,615 0 0
ASLAN PHARMACEUTICALS LTD ADS 04522R101 1,304 732,500 SH   SOLE 732,500 0 0
ATHIRA PHARMA INC COM 04746L104 1,510 160,983 SH   SOLE 160,983 0 0
ATRICURE INC COM 04963C209 5,010 72,029 SH   SOLE 72,029 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 12,238 88,100 SH   SOLE 88,100 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 21,273 206,911 SH   SOLE 206,911 0 0
BOLT BIOTHERAPEUTICS INC COM 097702104 1,265 100,000 SH   SOLE 100,000 0 0
BRAINWAY LTD SPONSORED ADS 10501L106 1,612 200,000 SH   SOLE 200,000 0 0
CARDIOVASCULAR SYS INC COM 141619106 6,361 193,741 SH   SOLE 193,741 0 0
CENTURY THERAPEUTICS INC COM 15673T100 2,013 80,000 SH   SOLE 80,000 0 0
COGENT BIOSCIENCES INC COM 19240Q201 1,880 223,554 SH   SOLE 223,554 0 0
COMPUGEN LTD ORD M25722105 1,203 201,502 SH   SOLE 201,502 0 0
CYMABAY THERAPEUTICS INC COM 23257D103 1,914 524,286 SH   SOLE 524,286 0 0
CYTOKINETICS INC COM NEW 23282W605 6,255 175,000 SH   SOLE 175,000 0 0
DEXCOM INC COM 252131107 11,560 21,138 SH   SOLE 21,138 0 0
DICERNA PHARMACEUTICALS INC COM 253031108 11,843 587,456 SH   SOLE 587,456 0 0
FATE THERAPEUTICS INC COM 31189P102 20,410 344,360 SH   SOLE 344,360 0 0
FIELD TRIP HEALTH LTD COM 31656R102 1,565 340,900 SH   SOLE 340,900 0 0
FS DEVELOPMENT CORP II COM CL A 30318F100 2,985 299,950 SH   SOLE 299,950 0 0
F-STAR THERAPEUTICS INC COM 30315R107 5,079 693,785 SH   SOLE 693,785 0 0
GALAPAGOS NV SPON ADR 36315X101 4,086 77,675 SH   SOLE 77,675 0 0
GENFIT S A ADS 372279109 698 188,549 SH   SOLE 188,549 0 0
HARPOON THERAPEUTICS INC COM 41358P106 831 105,163 SH   SOLE 105,163 0 0
HOOKIPA PHARMA INC COM 43906K100 1,897 322,124 SH   SOLE 322,124 0 0
IDEAYA BIOSCIENCES INC COM 45166A102 11,727 460,061 SH   SOLE 460,061 0 0
INFINITY PHARMACEUTICALS INC COM 45665G303 808 236,160 SH   SOLE 236,160 0 0
INFLARX NV COM N44821101 1,554 600,000 SH   SOLE 600,000 0 0
INOGEN INC COM 45780L104 646 15,000 SH   SOLE 15,000 0 0
ISHARES TR NASDAQ BIOTECH ETF 464287556 6,613 40,900 SH   SOLE 40,900 0 0
ITEOS THERAPEUTICS INC COM 46565G104 2,243 83,061 SH   SOLE 83,061 0 0
IVERIC BIO INC COM 46583P102 3,514 216,351 SH   SOLE 216,351 0 0
KADMON HLDGS INC COM 48283N106 2,740 314,561 SH   SOLE 314,561 0 0
KALVISTA PHARMACEUTICALS INC COM 483497103 3,301 189,163 SH   SOLE 189,163 0 0
KARUNA THERAPEUTICS INC COM 48576A100 9,124 74,585 SH   SOLE 74,585 0 0
KINNATE BIOPHARMA INC COM 49705R105 2,451 106,453 SH   SOLE 106,453 0 0
KURA ONCOLOGY INC COM 50127T109 1,889 100,829 SH   SOLE 100,829 0 0
LARIMAR THERAPEUTICS INC COM 517125100 744 64,487 SH   SOLE 64,487 0 0
LAVA THERAPEUTICS NV SHS N51517105 825 139,332 SH   SOLE 139,332 0 0
MACROGENICS INC COM 556099109 1,885 90,000 SH   SOLE 90,000 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105 447 5,600 SH   SOLE 5,600 0 0
MASIMO CORP COM 574795100 812 3,000 SH   SOLE 3,000 0 0
MEI PHARMA INC COM NEW 55279B202 1,769 641,000 SH   SOLE 641,000 0 0
MEREO BIOPHARMA GROUP PLC ADS 589492107 2,726 1,126,613 SH   SOLE 1,126,613 0 0
MERSANA THERAPEUTICS INC COM 59045L106 1,323 140,263 SH   SOLE 140,263 0 0
MERUS N V COM N5749R100 2,903 131,949 SH   SOLE 131,949 0 0
MORPHIC HLDG INC COM 61775R105 10,278 181,467 SH   SOLE 181,467 0 0
NATUS MED INC COM 639050103 2,399 95,653 SH   SOLE 95,653 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 8,119 84,655 SH   SOLE 84,655 0 0
NEURONETICS INC COM 64131A105 2,058 313,717 SH   SOLE 313,717 0 0
NEXTCURE INC COM 65343E108 1,237 183,491 SH   SOLE 183,491 0 0
NGM BIOPHARMACEUTICALS INC COM 62921N105 1,376 65,485 SH   SOLE 65,485 0 0
NURIX THERAPEUTICS INC COM 67080M103 9,177 306,320 SH   SOLE 306,320 0 0
OTONOMY INC COM 68906L105 4,568 2,379,392 SH   SOLE 2,379,392 0 0
PHARVARIS N V COM N69605108 622 35,074 SH   SOLE 35,074 0 0
PHASEBIO PHARMACEUTICALS INC COM 717224109 1,875 603,042 SH   SOLE 603,042 0 0
PROQR THERAPEUTICS N V SHS EURO N71542109 2,481 296,383 SH   SOLE 296,383 0 0
RADIUS HEALTH INC COM NEW 750469207 180 14,500 SH   SOLE 14,500 0 0
RADIUS HEALTH INC NOTE 3.000% 9/0 750469AA6 3,630 4,000,000 PRN   SOLE 4,000,000 0 0
REVOLUTION MEDICINES INC COM 76155X100 5,770 209,731 SH   SOLE 209,731 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 2,937 809,000 SH   SOLE 809,000 0 0
SAGE THERAPEUTICS INC COM 78667J108 7,989 180,306 SH   SOLE 180,306 0 0
STEREOTAXIS INC COM NEW 85916J409 73,601 13,680,554 SH   SOLE 13,680,554 0 0
SURGALIGN HOLDINGS INC COM 86882C105 632 579,710 SH   SOLE 579,710 0 0
SUTRO BIOPHARMA INC COM 869367102 1,606 85,000 SH   SOLE 85,000 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105 1,542 80,702 SH   SOLE 80,702 0 0
TURNING POINT THERAPEUTICS I COM 90041T108 2,787 41,952 SH   SOLE 41,952 0 0
VASCULAR BIOGENICS LTD COM M96883109 113 55,000 SH   SOLE 55,000 0 0
VENUS CONCEPT INC COM 92332W105 2,794 1,113,228 SH   SOLE 1,113,228 0 0
VIKING THERAPEUTICS INC COM 92686J106 2,810 447,400 SH   SOLE 447,400 0 0
XENON PHARMACEUTICALS INC COM 98420N105 6,212 406,535 SH   SOLE 406,535 0 0