The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
AES CORP COM 00130H105 62,465 2,736,096 SH   DFND 1, 2 1,361,269 0 1,374,827
ABBOTT LABS COM 002824100 61,699 522,301 SH   DFND 1, 2 337,972 0 184,329
ABCELLERA BIOLOGICS INC COM 00288U106 19,061 951,154 SH   DFND 1, 2 803,379 0 147,775
ACTIVISION BLIZZARD INC COM 00507V109 41,962 542,219 SH   DFND 1, 2 332,665 0 209,554
ADAGENE INC ADS 005329107 4,421 304,876 SH   DFND 1, 2 304,876 0 0
ADOBE SYSTEMS INCORPORATED COM 00724F101 85,398 148,333 SH   DFND 1, 2 80,308 0 68,025
ADVANCED MICRO DEVICES INC COM 007903107 11,893 115,582 SH   DFND 1, 2 90,119 0 25,463
AIRBNB INC COM CL A 009066101 1,383 8,246 SH   DFND 1, 2 5,958 0 2,288
AIR LEASE CORP CL A 00912X302 2,210 56,172 SH   DFND 1, 2 56,172 0 0
AIR PRODS & CHEMS INC COM 009158106 30,949 120,843 SH   DFND 1, 2 42,352 0 78,491
ALLEGHENY TECHNOLOGIES INC COM 01741R102 51,549 3,099,786 SH   DFND 1, 2 1,385,783 0 1,714,003
ALPHABET INC CAP STK CL C 02079K107 207,897 78,001 SH   DFND 1, 2 46,104 0 31,897
ALPHABET INC CAP STK CL A 02079K305 84,168 31,482 SH   DFND 1, 2 21,777 0 9,705
ALTERYX INC COM CL A 02156B103 2,639 36,100 SH   DFND 1, 2 28,100 0 8,000
ALTRIA GROUP INC COM 02209S103 1,479 32,490 SH   DFND 1, 2 32,490 0 0
AMAZON COM INC COM 023135106 222,811 67,826 SH   DFND 1, 2 45,974 0 21,852
AMERICA MOVIL SAB DE CV SPON ADR L SHS 02364W105 76,614 4,335,850 SH   DFND 1, 2 4,155,559 0 180,291
AMERICAN TOWER CORP NEW COM 03027X100 5,001 18,842 SH   DFND 1, 2 16,812 0 2,030
AMETEK INC COM 031100100 37,901 305,625 SH   DFND 1, 2 140,087 0 165,538
AMGEN INC COM 031162100 1,153 5,420 SH   DFND 1, 2 5,420 0 0
ANHEUSER BUSCH INBEV SA/NV SPONSORED ADR 03524A108 318 5,643 SH   DFND 1, 2 5,643 0 0
ANTHEM INC COM 036752103 35,847 96,155 SH   DFND 1, 2 44,237 0 51,918
APPLE INC COM 037833100 104,056 735,377 SH   DFND 1, 2 509,807 0 225,570
APPLIED MATLS INC COM 038222105 12,828 99,653 SH   DFND 1, 2 79,103 0 20,550
ARCHER DANIELS MIDLAND CO COM 039483102 1,504 25,056 SH   DFND 1, 2 19,570 0 5,486
ARCOSA INC COM 039653100 91,395 1,821,711 SH   DFND 1, 2 768,518 0 1,053,193
ARES MANAGEMENT CORPORATION CL A COM STK 03990B101 4,219 57,140 SH   DFND 1, 2 57,140 0 0
ARMSTRONG WORLD INDS INC NEW COM 04247X102 2,422 25,372 SH   DFND 1, 2 25,372 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108 2,152 35,839 SH   DFND 1, 2 35,839 0 0
BAKER HUGHES COMPANY CL A 05722G100 3,958 160,048 SH   DFND 1, 2 128,617 0 31,431
BK OF AMERICA CORP COM 060505104 43,101 1,015,336 SH   DFND 1, 2 543,266 0 472,070
BARRICK GOLD CORP COM 067901108 14,849 822,679 SH   DFND 1, 2 732,833 0 89,846
BEIGENE LTD SPONSORED ADR 07725L102 367,405 1,012,135 SH   DFND 1, 2 912,921 0 99,214
BILL COM HLDGS INC COM 090043100 62,860 235,473 SH   DFND 1, 2 108,604 0 126,869
BIONTECH SE SPONSORED ADS 09075V102 3,832 14,036 SH   DFND 1, 2 10,905 0 3,131
BLACKROCK INC COM 09247X101 23,753 28,322 SH   DFND 1, 2 21,966 0 6,356
BLACKSTONE INC COM 09260D107 6,935 59,609 SH   DFND 1, 2 56,965 0 2,644
BOEING CO COM 097023105 3,659 16,637 SH   DFND 1, 2 13,027 0 3,610
BOOKING HOLDINGS INC COM 09857L108 28,235 11,894 SH   DFND 1, 2 9,502 0 2,392
BROADCOM INC COM 11135F101 160,809 331,612 SH   DFND 1, 2 220,491 0 111,121
BROOKFIELD ASSET MGMT INC CL A LTD VT SH 112585104 18,033 337,000 SH   DFND 1, 2 280,411 0 56,589
BURLINGTON STORES INC COM 122017106 26,670 94,052 SH   DFND 1, 2 36,861 0 57,191
CDK GLOBAL INC COM 12508E101 28,721 674,985 SH   DFND 1, 2 333,959 0 341,026
CME GROUP INC COM 12572Q105 42,211 218,278 SH   DFND 1, 2 146,371 0 71,907
CMS ENERGY CORP COM 125896100 1,385 23,180 SH   DFND 1, 2 23,180 0 0
CSX CORP COM 126408103 4,950 166,458 SH   DFND 1, 2 166,458 0 0
CABLE ONE INC COM 12685J105 2,692 1,485 SH   DFND 1, 2 1,485 0 0
CAESARS ENTERTAINMENT INC NE COM 12769G100 4,200 37,405 SH   DFND 1, 2 37,405 0 0
CARRIER GLOBAL CORPORATION COM 14448C104 104,771 2,024,160 SH   DFND 1, 2 1,156,222 0 867,938
CATALENT INC COM 148806102 10,019 75,288 SH   DFND 1, 2 58,508 0 16,780
CATERPILLAR INC COM 149123101 9,193 47,889 SH   DFND 1, 2 40,087 0 7,802
CELANESE CORP DEL COM 150870103 4,763 31,619 SH   DFND 1, 2 31,619 0 0
CELLECTIS S A SPON ADS 15117K103 10,880 862,789 SH   DFND 1, 2 737,498 0 125,291
CENTENE CORP DEL COM 15135B101 39,961 641,327 SH   DFND 1, 2 314,547 0 326,780
CENTERPOINT ENERGY INC COM 15189T107 33,571 1,364,683 SH   DFND 1, 2 542,324 0 822,359
CERIDIAN HCM HLDG INC COM 15677J108 506 4,492 SH   DFND 1, 2 3,167 0 1,325
CHART INDS INC COM 16115Q308 1,467 7,678 SH   DFND 1, 2 5,946 0 1,732
CHARTER COMMUNICATIONS INC N CL A 16119P108 123,562 169,830 SH   DFND 1, 2 79,044 0 90,786
CHEVRON CORP NEW COM 166764100 28,815 284,029 SH   DFND 1, 2 146,195 0 137,834
CHIPOTLE MEXICAN GRILL INC COM 169656105 88,301 48,583 SH   DFND 1, 2 19,372 0 29,211
CHURCH & DWIGHT INC COM 171340102 36,164 437,976 SH   DFND 1, 2 188,885 0 249,091
CITIGROUP INC COM NEW 172967424 3,262 46,475 SH   DFND 1, 2 35,702 0 10,773
CITIZENS FINL GROUP INC COM 174610105 4,564 97,156 SH   DFND 1, 2 97,156 0 0
COMCAST CORP NEW CL A 20030N101 67,387 1,204,850 SH   DFND 1, 2 594,399 0 610,451
CONCENTRIX CORP COM 20602D101 1,831 10,346 SH   DFND 1, 2 10,346 0 0
CONOCOPHILLIPS COM 20825C104 75,911 1,120,123 SH   DFND 1, 2 560,949 0 559,174
CONSTELLATION BRANDS INC CL A 21036P108 19,641 93,224 SH   DFND 1, 2 36,781 0 56,443
COPART INC COM 217204106 12,359 89,094 SH   DFND 1, 2 69,366 0 19,728
COSTCO WHSL CORP NEW COM 22160K105 29,858 66,447 SH   DFND 1, 2 55,293 0 11,154
COUPANG INC CL A 22266T109 6,678 239,800 SH   DFND 1, 2 239,800 0 0
CREE INC COM 225447101 8,508 105,393 SH   DFND 1, 2 90,371 0 15,022
CROWN CASTLE INTL CORP NEW COM 22822V101 34,550 199,344 SH   DFND 1, 2 108,439 0 90,905
D R HORTON INC COM 23331A109 21,003 250,129 SH   DFND 1, 2 99,344 0 150,785
DANAHER CORPORATION COM 235851102 94,759 311,257 SH   DFND 1, 2 188,167 0 123,090
DANIMER SCIENTIFIC INC COM CL A 236272100 877 53,677 SH   DFND 1, 2 53,677 0 0
DEERE & CO COM 244199105 7,374 22,008 SH   DFND 1, 2 22,008 0 0
DELL TECHNOLOGIES INC CL C 24703L202 4,460 42,869 SH   DFND 1, 2 33,545 0 9,324
DELTA AIR LINES INC DEL COM NEW 247361702 5,764 135,265 SH   DFND 1, 2 104,253 0 31,012
DIGITAL RLTY TR INC COM 253868103 2,211 15,307 SH   DFND 1, 2 15,307 0 0
DISCOVER FINL SVCS COM 254709108 5,011 40,793 SH   DFND 1, 2 40,793 0 0
DOCUSIGN INC COM 256163106 8,363 32,487 SH   DFND 1, 2 25,190 0 7,297
DOLLAR GEN CORP NEW COM 256677105 40,051 188,793 SH   DFND 1, 2 87,693 0 101,100
DOLLAR TREE INC COM 256746108 19,182 200,394 SH   DFND 1, 2 80,048 0 120,346
DOMINOS PIZZA INC COM 25754A201 2,539 5,323 SH   DFND 1, 2 4,178 0 1,145
DOW INC COM 260557103 6,277 109,051 SH   DFND 1, 2 88,688 0 20,363
DUN & BRADSTREET HLDGS INC COM 26484T106 26,456 1,573,810 SH   DFND 1, 2 823,945 0 749,865
EOG RES INC COM 26875P101 58,747 731,869 SH   DFND 1, 2 431,621 0 300,248
EAST WEST BANCORP INC COM 27579R104 6,118 78,895 SH   DFND 1, 2 78,895 0 0
EDWARDS LIFESCIENCES CORP COM 28176E108 68,483 604,919 SH   DFND 1, 2 336,605 0 268,314
ELECTRONIC ARTS INC COM 285512109 4,039 28,397 SH   DFND 1, 2 23,413 0 4,984
ENDEAVOR GROUP HLDGS INC CL A COM 29260Y109 3,287 114,647 SH   DFND 1, 2 114,647 0 0
ENPHASE ENERGY INC COM 29355A107 18,708 124,742 SH   DFND 1, 2 49,924 0 74,818
EPAM SYS INC COM 29414B104 15,142 26,543 SH   DFND 1, 2 19,914 0 6,629
EQUIFAX INC COM 294429105 72,690 286,836 SH   DFND 1, 2 143,886 0 142,950
EQUINIX INC COM 29444U700 70,803 89,609 SH   DFND 1, 2 48,236 0 41,373
EQUITRANS MIDSTREAM CORP COM 294600101 33,047 3,259,058 SH   DFND 1, 2 1,346,715 0 1,912,343
ETSY INC COM 29786A106 7,507 36,098 SH   DFND 1, 2 28,036 0 8,062
EXELON CORP COM 30161N101 318 6,586 SH   DFND 1, 2 6,586 0 0
FTI CONSULTING INC COM 302941109 3,010 22,343 SH   DFND 1, 2 22,343 0 0
FACEBOOK INC CL A 30303M102 263,344 775,933 SH   DFND 1, 2 481,344 0 294,589
FIDELITY NATL INFORMATION SV COM 31620M106 20,585 169,174 SH   DFND 1, 2 154,723 0 14,451
FLEETCOR TECHNOLOGIES INC COM 339041105 6,735 25,778 SH   DFND 1, 2 21,092 0 4,686
GALAPAGOS NV SPON ADR 36315X101 1,441 27,393 SH   DFND 1, 2 27,393 0 0
GALLAGHER ARTHUR J & CO COM 363576109 216 1,456 SH   DFND 1, 2 1,456 0 0
GAMING & LEISURE PPTYS INC COM 36467J108 2,210 47,707 SH   DFND 1, 2 47,707 0 0
GENERAL ELECTRIC CO COM NEW 369604301 1,422 13,799 SH   DFND 1, 2 10,796 0 3,003
GENERAL MLS INC COM 370334104 6,767 113,129 SH   DFND 1, 2 103,517 0 9,612
GENERAL MTRS CO COM 37045V100 4,177 79,240 SH   DFND 1, 2 61,302 0 17,938
GERDAU SA SPON ADR REP PFD 373737105 12,865 2,614,838 SH   DFND 1, 2 2,453,433 0 161,405
GILEAD SCIENCES INC COM 375558103 5,797 82,985 SH   DFND 1, 2 82,985 0 0
GLOBAL PMTS INC COM 37940X102 1,217 7,720 SH   DFND 1, 2 7,720 0 0
GODADDY INC CL A 380237107 58,281 836,165 SH   DFND 1, 2 590,105 0 246,060
GOL LINHAS AEREAS INTELIGENT SPON ADR PFD NEW 38045R206 8,897 1,166,100 SH   DFND 1, 2 1,166,100 0 0
GOLDMAN SACHS GROUP INC COM 38141G104 2,526 6,681 SH   DFND 1, 2 4,703 0 1,978
GRACELL BIOTECHNOLOGIES INC SPONSORED ADS 38406L103 16,102 1,160,891 SH   DFND 1, 2 1,160,891 0 0
GRIFOLS S A SP ADR REP B NVT 398438408 4,498 307,839 SH   DFND 1, 2 238,650 0 69,189
GUARDANT HEALTH INC COM 40131M109 3,714 29,709 SH   DFND 1, 2 29,709 0 0
HDFC BANK LTD SPONSORED ADS 40415F101 60,937 833,721 SH   DFND 1, 2 617,646 0 216,075
HEICO CORP NEW COM 422806109 1,665 12,623 SH   DFND 1, 2 12,623 0 0
HEICO CORP NEW CL A 422806208 30,875 260,700 SH   DFND 1, 2 108,492 0 152,208
HENRY JACK & ASSOC INC COM 426281101 254 1,546 SH   DFND 1, 2 1,546 0 0
HILTON GRAND VACATIONS INC COM 43283X105 71,807 1,509,501 SH   DFND 1, 2 699,887 0 809,614
HILTON WORLDWIDE HLDGS INC COM 43300A203 34,973 264,730 SH   DFND 1, 2 236,791 0 27,939
HOME DEPOT INC COM 437076102 21,648 65,948 SH   DFND 1, 2 51,406 0 14,542
HONEYWELL INTL INC COM 438516106 28,818 135,756 SH   DFND 1, 2 114,696 0 21,060
HUAZHU GROUP LTD SPONSORED ADS 44332N106 72,723 1,585,763 SH   DFND 1, 2 1,585,763 0 0
HUBSPOT INC COM 443573100 12,737 18,839 SH   DFND 1, 2 14,615 0 4,224
HUMANA INC COM 444859102 265 682 SH   DFND 1, 2 682 0 0
HUTCHMED CHINA LTD SPONSORED ADS 44842L103 153,303 4,187,449 SH   DFND 1, 2 3,835,997 0 351,452
ICICI BANK LIMITED ADR 45104G104 91,399 4,843,608 SH   DFND 1, 2 4,439,886 0 403,722
IDEX CORP COM 45167R104 7,146 34,529 SH   DFND 1, 2 27,117 0 7,412
IDEXX LABS INC COM 45168D104 17,928 28,828 SH   DFND 1, 2 22,471 0 6,357
INCYTE CORP COM 45337C102 7,691 111,821 SH   DFND 1, 2 94,539 0 17,282
INFOSYS LTD SPONSORED ADR 456788108 3,912 175,839 SH   DFND 1, 2 127,579 0 48,260
INSULET CORP COM 45784P101 15,411 54,220 SH   DFND 1, 2 42,213 0 12,007
INTEL CORP COM 458140100 36,489 684,856 SH   DFND 1, 2 425,987 0 258,869
INTERCONTINENTAL EXCHANGE IN COM 45866F104 77,824 677,788 SH   DFND 1, 2 403,858 0 273,930
INTERNATIONAL FLAVORS&FRAGRA COM 459506101 7,356 55,010 SH   DFND 1, 2 42,885 0 12,125
INTUITIVE SURGICAL INC COM NEW 46120E602 38,651 38,878 SH   DFND 1, 2 30,238 0 8,640
IRIDIUM COMMUNICATIONS INC COM 46269C102 2,252 56,508 SH   DFND 1, 2 56,508 0 0
JPMORGAN CHASE & CO COM 46625H100 134,496 821,651 SH   DFND 1, 2 524,176 0 297,475
KLA CORP COM NEW 482480100 7,479 22,357 SH   DFND 1, 2 22,357 0 0
KKR & CO INC COM 48251W104 1,620 26,604 SH   DFND 1, 2 26,604 0 0
KEURIG DR PEPPER INC COM 49271V100 3,575 104,666 SH   DFND 1, 2 104,666 0 0
KRAFT HEINZ CO COM 500754106 25,940 704,514 SH   DFND 1, 2 273,595 0 430,919
L3HARRIS TECHNOLOGIES INC COM 502431109 45,494 206,564 SH   DFND 1, 2 86,669 0 119,895
LAM RESEARCH CORP COM 512807108 55,355 97,259 SH   DFND 1, 2 38,407 0 58,852
LAS VEGAS SANDS CORP COM 517834107 587 16,040 SH   DFND 1, 2 16,040 0 0
LAUDER ESTEE COS INC CL A 518439104 38,043 126,841 SH   DFND 1, 2 50,563 0 76,278
LEGEND BIOTECH CORP SPONSORED ADS 52490G102 97,068 1,919,866 SH   DFND 1, 2 1,919,866 0 0
LENNOX INTL INC COM 526107107 4,620 15,705 SH   DFND 1, 2 12,260 0 3,445
LIGHTSPEED COMMERCE INC SUB VTG SHS 53229C107 98,614 1,022,524 SH   DFND 1, 2 807,832 0 214,692
LILLY ELI & CO COM 532457108 17,365 75,156 SH   DFND 1, 2 67,452 0 7,704
LOCKHEED MARTIN CORP COM 539830109 4,506 13,058 SH   DFND 1, 2 13,058 0 0
LOMA NEGRA C I A S A MTN 14 SPONSORED ADS 54150E104 8,245 1,156,356 SH   DFND 1, 2 1,156,356 0 0
LUFAX HOLDING LTD ADS REP SHS CL A 54975P102 4,885 699,905 SH   DFND 1, 2 620,447 0 79,458
LULULEMON ATHLETICA INC COM 550021109 9,571 23,649 SH   DFND 1, 2 18,406 0 5,243
MSCI INC COM 55354G100 58,292 95,822 SH   DFND 1, 2 37,039 0 58,783
MARSH & MCLENNAN COS INC COM 571748102 56,952 376,094 SH   DFND 1, 2 163,207 0 212,887
MASTERCARD INCORPORATED CL A 57636Q104 107,297 308,608 SH   DFND 1, 2 166,848 0 141,760
MELCO RESORTS AND ENTMNT LTD ADR 585464100 2,385 232,879 SH   DFND 1, 2 180,174 0 52,705
MERCADOLIBRE INC COM 58733R102 103,644 61,715 SH   DFND 1, 2 50,970 0 10,745
MERCK & CO INC COM 58933Y105 872 11,604 SH   DFND 1, 2 11,604 0 0
METTLER TOLEDO INTERNATIONAL COM 592688105 8,374 6,080 SH   DFND 1, 2 4,984 0 1,096
MICROSOFT CORP COM 594918104 313,076 1,110,514 SH   DFND 1, 2 711,739 0 398,775
MICRON TECHNOLOGY INC COM 595112103 77,065 1,085,722 SH   DFND 1, 2 506,170 0 579,552
MODERNA INC COM 60770K107 898 2,333 SH   DFND 1, 2 1,778 0 555
MOLSON COORS BEVERAGE CO CL B 60871R209 27,721 597,698 SH   DFND 1, 2 180,755 0 416,943
MONDELEZ INTL INC CL A 609207105 14,484 248,943 SH   DFND 1, 2 206,960 0 41,983
MONSTER BEVERAGE CORP NEW COM 61174X109 2,528 28,454 SH   DFND 1, 2 22,195 0 6,259
MOODYS CORP COM 615369105 89,431 251,840 SH   DFND 1, 2 155,870 0 95,970
MORGAN STANLEY COM NEW 617446448 3,063 31,472 SH   DFND 1, 2 21,806 0 9,666
MOTOROLA SOLUTIONS INC COM NEW 620076307 10,009 43,084 SH   DFND 1, 2 33,607 0 9,477
NVR INC COM 62944T105 3,428 715 SH   DFND 1, 2 715 0 0
NASDAQ INC COM 631103108 41,672 215,896 SH   DFND 1, 2 86,694 0 129,202
NETAPP INC COM 64110D104 7,370 82,112 SH   DFND 1, 2 82,112 0 0
NETFLIX INC COM 64110L106 140,669 230,476 SH   DFND 1, 2 139,872 0 90,604
NETEASE INC SPONSORED ADS 64110W102 40,605 475,474 SH   DFND 1, 2 460,236 0 15,238
NEUROCRINE BIOSCIENCES INC COM 64125C109 27,881 290,704 SH   DFND 1, 2 124,714 0 165,990
NEWMONT CORP COM 651639106 3,219 59,281 SH   DFND 1, 2 59,281 0 0
NEXTERA ENERGY INC COM 65339F101 201 2,559 SH   DFND 1, 2 2,559 0 0
NICE LTD SPONSORED ADR 653656108 78,224 275,398 SH   DFND 1, 2 230,296 0 45,102
NIKE INC CL B 654106103 67,015 461,443 SH   DFND 1, 2 277,780 0 183,663
NORFOLK SOUTHN CORP COM 655844108 2,117 8,850 SH   DFND 1, 2 8,850 0 0
NORTHROP GRUMMAN CORP COM 666807102 10,076 27,976 SH   DFND 1, 2 27,480 0 496
NOVO-NORDISK A S ADR 670100205 238 2,479 SH   DFND 1, 2 2,479 0 0
NVIDIA CORPORATION COM 67066G104 7,411 35,773 SH   DFND 1, 2 31,303 0 4,470
OAK STR HEALTH INC COM 67181A107 3,574 84,041 SH   DFND 1, 2 84,041 0 0
OKTA INC CL A 679295105 19,528 82,278 SH   DFND 1, 2 38,151 0 44,127
ON SEMICONDUCTOR CORP COM 682189105 68,961 1,506,677 SH   DFND 1, 2 737,428 0 769,249
PG&E CORP COM 69331C108 3,439 358,214 SH   DFND 1, 2 358,214 0 0
PPG INDS INC COM 693506107 3,642 25,470 SH   DFND 1, 2 19,811 0 5,659
PARK HOTELS & RESORTS INC COM 700517105 46,197 2,413,623 SH   DFND 1, 2 933,775 0 1,479,848
PAYCHEX INC COM 704326107 916 8,148 SH   DFND 1, 2 8,148 0 0
PAYPAL HLDGS INC COM 70450Y103 116,854 449,075 SH   DFND 1, 2 287,918 0 161,157
PEPSICO INC COM 713448108 1,238 8,230 SH   DFND 1, 2 8,230 0 0
PFIZER INC COM 717081103 9,425 219,133 SH   DFND 1, 2 170,370 0 48,763
PHILIP MORRIS INTL INC COM 718172109 80,887 853,324 SH   DFND 1, 2 532,094 0 321,230
PINTEREST INC CL A 72352L106 26,621 522,501 SH   DFND 1, 2 237,025 0 285,476
PROCTER AND GAMBLE CO COM 742718109 529 3,783 SH   DFND 1, 2 3,783 0 0
QIWI PLC SPON ADR REP B 74735M108 3,373 402,508 SH   DFND 1, 2 402,508 0 0
QUALCOMM INC COM 747525103 742 5,754 SH   DFND 1, 2 5,754 0 0
QUALTRICS INTL INC COM CL A 747601201 2,760 64,584 SH   DFND 1, 2 64,584 0 0
RAYTHEON TECHNOLOGIES CORP COM 75513E101 3,021 35,149 SH   DFND 1, 2 35,149 0 0
REGENERON PHARMACEUTICALS COM 75886F107 18,642 30,804 SH   DFND 1, 2 23,938 0 6,866
RESTAURANT BRANDS INTL INC COM 76131D103 6,822 111,491 SH   DFND 1, 2 86,986 0 24,505
RINGCENTRAL INC CL A 76680R206 1,740 8,002 SH   DFND 1, 2 8,002 0 0
ROCKWELL AUTOMATION INC COM 773903109 3,080 10,476 SH   DFND 1, 2 8,156 0 2,320
RYANAIR HOLDINGS PLC SPONSORED ADS 783513203 83,363 757,428 SH   DFND 1, 2 617,804 0 139,624
RYAN SPECIALTY GROUP HLDGS I CL A 78351F107 24,635 727,346 SH   DFND 1, 2 216,216 0 511,130
S&P GLOBAL INC COM 78409V104 15,726 37,011 SH   DFND 1, 2 32,421 0 4,590
SVB FINANCIAL GROUP COM 78486Q101 81,801 126,454 SH   DFND 1, 2 61,316 0 65,138
SAIA INC COM 78709Y105 36,904 155,039 SH   DFND 1, 2 60,687 0 94,352
SCHLUMBERGER LTD COM STK 806857108 7,501 253,083 SH   DFND 1, 2 210,021 0 43,062
SEA LTD SPONSORD ADS 81141R100 122,066 382,977 SH   DFND 1, 2 324,470 0 58,507
SEAGEN INC COM 81181C104 88,071 518,675 SH   DFND 1, 2 290,512 0 228,163
SEMPRA COM 816851109 16,157 127,725 SH   DFND 1, 2 118,610 0 9,115
SERVICENOW INC COM 81762P102 78,425 126,030 SH   DFND 1, 2 68,535 0 57,495
SHERWIN WILLIAMS CO COM 824348106 40,350 144,247 SH   DFND 1, 2 82,316 0 61,931
SHOPIFY INC CL A 82509L107 41,850 30,855 SH   DFND 1, 2 23,689 0 7,166
SILICON LABORATORIES INC COM 826919102 2,401 17,131 SH   DFND 1, 2 17,131 0 0
SMARTSHEET INC COM CL A 83200N103 10,594 153,945 SH   DFND 1, 2 119,320 0 34,625
SNAP INC CL A 83304A106 7,049 95,421 SH   DFND 1, 2 73,897 0 21,524
STATE STR CORP COM 857477103 408 4,810 SH   DFND 1, 2 4,810 0 0
TFI INTL INC COM 87241L109 88,279 862,901 SH   DFND 1, 2 739,787 0 123,114
TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADS 874039100 147,984 1,325,426 SH   DFND 1, 2 877,592 0 447,834
TANDEM DIABETES CARE INC COM NEW 875372203 5,321 44,568 SH   DFND 1, 2 34,643 0 9,925
TC ENERGY CORP COM 87807B107 10,909 226,669 SH   DFND 1, 2 205,876 0 20,793
TELADOC HEALTH INC COM 87918A105 604 4,764 SH   DFND 1, 2 3,390 0 1,374
TELUS INTL CDA INC SUB VTG SHS 87975H100 52,665 1,504,281 SH   DFND 1, 2 1,282,483 0 221,798
TESLA INC COM 88160R101 220,075 283,792 SH   DFND 1, 2 220,684 0 63,108
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS 881624209 1,709 175,457 SH   DFND 1, 2 175,457 0 0
TEXAS INSTRS INC COM 882508104 1,445 7,518 SH   DFND 1, 2 7,518 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102 30,900 54,084 SH   DFND 1, 2 42,087 0 11,997
TOAST INC CL A 888787108 1,124 22,500 SH   DFND 1, 2 22,500 0 0
TOLL BROTHERS INC COM 889478103 4,098 74,121 SH   DFND 1, 2 74,121 0 0
TRANSDIGM GROUP INC COM 893641100 71,826 115,001 SH   DFND 1, 2 62,139 0 52,862
TRIMBLE INC COM 896239100 81,163 986,780 SH   DFND 1, 2 495,709 0 491,071
TRINITY INDS INC COM 896522109 2,170 79,866 SH   DFND 1, 2 79,866 0 0
TRIP COM GROUP LTD ADS 89677Q107 94,784 3,082,393 SH   DFND 1, 2 3,030,748 0 51,645
TRUPANION INC COM 898202106 2,159 27,802 SH   DFND 1, 2 27,802 0 0
TRUIST FINL CORP COM 89832Q109 2,030 34,604 SH   DFND 1, 2 34,604 0 0
UBER TECHNOLOGIES INC COM 90353T100 4,762 106,294 SH   DFND 1, 2 82,893 0 23,401
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 31,702 351,499 SH   DFND 1, 2 181,550 0 169,949
UNION PAC CORP COM 907818108 419 2,136 SH   DFND 1, 2 2,136 0 0
UNITEDHEALTH GROUP INC COM 91324P102 67,655 173,146 SH   DFND 1, 2 95,236 0 77,910
V F CORP COM 918204108 3,626 54,127 SH   DFND 1, 2 54,127 0 0
VALE S A SPONSORED ADS 91912E105 183,717 13,169,663 SH   DFND 1, 2 11,220,864 0 1,948,799
VERISIGN INC COM 92343E102 6,179 30,138 SH   DFND 1, 2 30,138 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 16,978 93,601 SH   DFND 1, 2 72,751 0 20,850
VIATRIS INC COM 92556V106 255 18,855 SH   DFND 1, 2 15,313 0 3,542
VICI PPTYS INC COM 925652109 4,278 150,594 SH   DFND 1, 2 150,594 0 0
VIR BIOTECHNOLOGY INC COM 92764N102 2,480 56,991 SH   DFND 1, 2 43,711 0 13,280
VISA INC COM CL A 92826C839 106,987 480,302 SH   DFND 1, 2 297,023 0 183,279
WALGREENS BOOTS ALLIANCE INC COM 931427108 7,573 160,961 SH   DFND 1, 2 125,524 0 35,437
WASTE CONNECTIONS INC COM 94106B101 50,008 397,113 SH   DFND 1, 2 173,209 0 223,904
WASTE MGMT INC DEL COM 94106L109 231 1,545 SH   DFND 1, 2 1,545 0 0
WEBSTER FINL CORP CONN COM 947890109 605 11,102 SH   DFND 1, 2 11,102 0 0
WORKDAY INC CL A 98138H101 2,019 8,078 SH   DFND 1, 2 6,037 0 2,041
WYNN RESORTS LTD COM 983134107 21,140 249,435 SH   DFND 1, 2 63,868 0 185,567
XPENG INC ADS 98422D105 23,216 653,225 SH   DFND 1, 2 564,722 0 88,503
YUM BRANDS INC COM 988498101 46,369 379,108 SH   DFND 1, 2 187,672 0 191,436
ZAI LAB LTD ADR 98887Q104 6,818 64,697 SH   DFND 1, 2 48,139 0 16,558
ZENDESK INC COM 98936J101 7,614 65,419 SH   DFND 1, 2 50,633 0 14,786
ZIMMER BIOMET HOLDINGS INC COM 98956P102 1,868 12,765 SH   DFND 1, 2 12,765 0 0
ZOETIS INC CL A 98978V103 22,369 115,220 SH   DFND 1, 2 90,023 0 25,197
AON PLC SHS CL A G0403H108 98,307 344,008 SH   DFND 1, 2 150,810 0 193,198
ARCH CAP GROUP LTD ORD G0450A105 9,921 259,860 SH   DFND 1, 2 201,804 0 58,056
ATLASSIAN CORP PLC CL A G06242104 75,508 192,908 SH   DFND 1, 2 162,771 0 30,137
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 65,771 473,478 SH   DFND 1, 2 195,177 0 278,301
BUNGE LIMITED COM G16962105 10,998 135,242 SH   DFND 1, 2 105,205 0 30,037
DLOCAL LTD CLASS A COM G29018101 61,276 1,123,100 SH   DFND 1, 2 1,123,100 0 0
EVEREST RE GROUP LTD COM G3223R108 2,057 8,201 SH   DFND 1, 2 7,289 0 912
FABRINET SHS G3323L100 3,388 33,052 SH   DFND 1, 2 33,052 0 0
GENPACT LIMITED SHS G3922B107 42,179 887,785 SH   DFND 1, 2 887,785 0 0
HELEN OF TROY LTD COM G4388N106 2,981 13,267 SH   DFND 1, 2 13,267 0 0
LINDE PLC SHS G5494J103 11,423 38,937 SH   DFND 1, 2 32,398 0 6,539
APTIV PLC SHS G6095L109 2,626 17,628 SH   DFND 1, 2 13,828 0 3,800
NOVOCURE LTD ORD SHS G6674U108 16,776 144,410 SH   DFND 1, 2 120,152 0 24,258
PAGSEGURO DIGITAL LTD COM CL A G68707101 53,138 1,027,421 SH   DFND 1, 2 1,005,926 0 21,495
PATRIA INVESTMENTS LIMITED COM CL A G69451105 18,943 1,160,022 SH   DFND 1, 2 1,160,022 0 0
RENAISSANCERE HLDGS LTD COM G7496G103 27,678 198,550 SH   DFND 1, 2 86,611 0 111,939
ROYALTY PHARMA PLC SHS CLASS A G7709Q104 22,195 614,131 SH   DFND 1, 2 142,152 0 471,979
CHUBB LIMITED COM H1467J104 65,601 378,146 SH   DFND 1, 2 213,895 0 164,251
CRISPR THERAPEUTICS AG NAMEN AKT H17182108 5,502 49,158 SH   DFND 1, 2 37,912 0 11,246
UBS GROUP AG SHS H42097107 29,461 1,831,031 SH   DFND 1, 2 1,625,717 0 205,314
LOGITECH INTL S A SHS H50430232 34,768 389,168 SH   DFND 1, 2 320,927 0 68,241
TE CONNECTIVITY LTD REG SHS H84989104 16,060 117,037 SH   DFND 1, 2 91,429 0 25,608
NEXA RES S A COM L67359106 5,927 779,822 SH   DFND 1, 2 779,822 0 0
SPOTIFY TECHNOLOGY S A SHS L8681T102 6,271 27,829 SH   DFND 1, 2 27,829 0 0
ASML HOLDING N V N Y REGISTRY SHS N07059210 280,205 376,058 SH   DFND 1, 2 247,807 0 128,251
ELASTIC N V ORD SHS N14506104 2,684 18,014 SH   DFND 1, 2 18,014 0 0
LYONDELLBASELL INDUSTRIES N SHS - A - N53745100 10,995 117,157 SH   DFND 1, 2 96,820 0 20,337
STELLANTIS N.V SHS N82405106 6,801 354,163 SH   DFND 1, 2 271,243 0 82,920
YANDEX N V SHS CLASS A N97284108 220,242 2,763,732 SH   DFND 1, 2 2,407,462 0 356,270
MAKEMYTRIP LIMITED MAURITIUS SHS V5633W109 5,715 210,190 SH   DFND 1, 2 210,190 0 0
ROYAL CARIBBEAN GROUP COM V7780T103 75,630 850,248 SH   DFND 1, 2 462,527 0 387,721