The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
9 METERS BIOPHARMA INC COM 654405109 3,575 2,750,000 SH   SOLE   2,750,000 0 0
ACLARIS THERAPEUTICS INC COM 00461U105 4,950 275,000 SH   SOLE   275,000 0 0
ALDEYRA THERAPEUTICS INC COM 01438T106 6,146 700,000 SH   SOLE   700,000 0 0
ALECTOR INC COM 014442107 1,826 80,000 SH   SOLE   80,000 0 0
ALLAKOS INC COM 01671P100 8,999 85,000 SH   SOLE   85,000 0 0
ALLOGENE THERAPEUTICS INC COM 019770106 3,855 150,000 SH   SOLE   150,000 0 0
AMICUS THERAPEUTICS INC COM 03152W109 2,531 265,000 SH   SOLE   265,000 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106 6,592 200,000 SH   SOLE   200,000 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106 4,944 150,000 SH Call SOLE   150,000 0 0
ARVINAS INC COM 04335A105 12,327 150,000 SH   SOLE   150,000 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101 19,127 120,000 SH   SOLE   120,000 0 0
ATEA PHARMACEUTICALS INC COM 04683R106 5,259 150,000 SH   SOLE   150,000 0 0
BELLUS HEALTH INC NEW COM NEW 07987C204 2,456 400,000 SH   SOLE   400,000 0 0
BEYONDSPRING INC SHS G10830100 6,304 400,000 SH Call SOLE   400,000 0 0
BICYCLE THERAPEUTICS PLC SPONSORED ADS 088786108 4,159 100,000 SH   SOLE   100,000 0 0
BIONTECH SE SPONSORED ADS 09075V102 546 2,000 SH   SOLE   2,000 0 0
CABALETTA BIO INC COM 12674W109 1,216 100,000 SH   SOLE   100,000 0 0
CASI PHARMACEUTICALS INC COM 14757U109 774 650,000 SH   SOLE   650,000 0 0
CATALYST BIOSCIENCES INC COM NEW 14888D208 4,110 1,000,000 SH   SOLE   1,000,000 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 13,767 255,000 SH   SOLE   255,000 0 0
CHIMERIX INC COM 16934W106 1,238 200,000 SH   SOLE   200,000 0 0
CODEX DNA INC COM 192003101 390 35,000 SH   SOLE   35,000 0 0
COGENT BIOSCIENCES INC COM 19240Q201 12,615 1,500,000 SH   SOLE   1,500,000 0 0
COMPASS PATHWAYS PLC SPONSORED ADS 20451W101 2,987 100,000 SH   SOLE   100,000 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107 3,158 150,000 SH   SOLE   150,000 0 0
CTI BIOPHARMA CORP COM 12648L601 4,720 1,600,000 SH   SOLE   1,600,000 0 0
FATE THERAPEUTICS INC COM 31189P102 2,964 50,000 SH   SOLE   50,000 0 0
FULCRUM THERAPEUTICS INC COM 359616109 1,411 50,000 SH   SOLE   50,000 0 0
GH RESEARCH PLC ORDINARY SHARES G3855L106 8,824 400,000 SH   SOLE   400,000 0 0
HARMONY BIOSCIENCES HLDGS IN COM 413197104 2,875 75,000 SH   SOLE   75,000 0 0
HELIX ACQUISITION CORP COM CL A G4444C102 4,943 500,000 SH   SOLE   500,000 0 0
IMMUNIC INC COM 4525EP101 2,345 265,000 SH   SOLE   265,000 0 0
IMMUNOVANT INC COM 45258J102 1,738 200,000 SH Call SOLE   200,000 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100 17,262 700,000 SH   SOLE   700,000 0 0
ISHARES TR RUSSELL 2000 ETF 464287655 21,875 100,000 SH Call SOLE   100,000 0 0
IVERIC BIO INC COM 46583P102 11,774 725,000 SH   SOLE   725,000 0 0
KURA ONCOLOGY INC COM 50127T109 7,960 425,000 SH   SOLE   425,000 0 0
LARIMAR THERAPEUTICS INC COM 517125100 2,306 200,000 SH   SOLE   200,000 0 0
LEAP THERAPEUTICS INC COM 52187K101 6,617 1,650,000 SH   SOLE   1,650,000 0 0
MERUS N V COM N5749R100 1,650 75,000 SH   SOLE   75,000 0 0
MIRATI THERAPEUTICS INC COM 60468T105 10,615 60,000 SH   SOLE   60,000 0 0
MODERNA INC COM 60770K107 2,040 5,300 SH   SOLE   5,300 0 0
OTONOMY INC COM 68906L105 864 450,000 SH   SOLE   450,000 0 0
PRAXIS PRECISION MEDICINES I COM 74006W108 4,623 250,000 SH   SOLE   250,000 0 0
PROVENTION BIO INC COM 74374N102 320 50,000 SH   SOLE   50,000 0 0
RAPT THERAPEUTICS INC COM 75382E109 7,763 250,000 SH   SOLE   250,000 0 0
RELMADA THERAPEUTICS INC COM 75955J402 5,242 200,000 SH   SOLE   200,000 0 0
ROCKET PHARMACEUTICALS INC COM 77313F106 10,462 350,000 SH   SOLE   350,000 0 0
SATSUMA PHARMACEUTICALS INC COM 80405P107 4,214 904,225 SH   SOLE   904,225 0 0
SIERRA ONCOLOGY INC COM NEW 82640U404 4,384 200,000 SH   SOLE   200,000 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105 10,988 575,000 SH   SOLE   575,000 0 0
TARSUS PHARMACEUTICALS INC COM 87650L103 3,664 170,000 SH   SOLE   170,000 0 0
TCR2 THERAPEUTICS INC COM 87808K106 4,062 477,323 SH   SOLE   477,323 0 0
VAXCYTE INC COM 92243G108 4,059 160,000 SH   SOLE   160,000 0 0
VERONA PHARMA PLC SPONSORED ADS 925050106 4,110 750,000 SH   SOLE   750,000 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104 5,758 350,000 SH   SOLE   350,000 0 0
VISTAGEN THERAPEUTICS INC COM NEW 92840H202 5,480 2,000,000 SH   SOLE   2,000,000 0 0
XENON PHARMACEUTICALS INC COM 98420N105 12,071 790,000 SH   SOLE   790,000 0 0
XENON PHARMACEUTICALS INC COM 98420N105 3,820 250,000 SH Put SOLE   250,000 0 0
ZENTALIS PHARMACEUTICALS INC COM 98943L107 4,332 65,000 SH   SOLE   65,000 0 0