The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
AC IMMUNE SA SHS H00263105 1,488 221,749 SH   SOLE   221,749 0 0
ACCELERON PHARMA INC COM 00434H108 60,148 349,494 SH   SOLE   349,494 0 0
ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107 2,300 444,887 SH   SOLE   444,887 0 0
AGILENT TECHNOLOGIES INC COM 00846U101 2,940 18,660 SH   SOLE   18,660 0 0
AKOYA BIOSCIENCES INC COM 00974H104 1,278 91,568 SH   SOLE   91,568 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 11,184 59,233 SH   SOLE   59,233 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206 59,185 11,604,990 SH   SOLE   11,604,990 0 0
AMN HEALTHCARE SVCS INC COM 001744101 1,148 10,000 SH   SOLE   10,000 0 0
AMNEAL PHARMACEUTICALS INC COM STK CL A 03168L105 36,578 6,849,834 SH   SOLE   6,849,834 0 0
ANAPTYSBIO INC COM 032724106 2,117 78,054 SH   SOLE   78,054 0 0
ANTHEM INC COM 036752103 11,791 31,628 SH   SOLE   31,628 0 0
ARGENX SE SPONSORED ADR 04016X101 1,735 5,746 SH   SOLE   5,746 0 0
ARK ETF TR GENOMIC REV ETF 00214Q302 51,520 689,501 SH   SOLE   689,501 0 0
ARK ETF TR INNOVATION ETF 00214Q104 3,869 35,000 SH   SOLE   35,000 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101 70,961 445,203 SH   SOLE   445,203 0 0
ASSEMBLY BIOSCIENCES INC COM 045396108 1,218 350,000 SH   SOLE   350,000 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108 53,502 890,808 SH   SOLE   890,808 0 0
AUTOLUS THERAPEUTICS PLC SPON ADS 05280R100 2,607 398,074 SH   SOLE   398,074 0 0
AVANTOR INC COM 05352A100 52,843 1,292,014 SH   SOLE   1,292,014 0 0
AVROBIO INC COM 05455M100 2,006 359,480 SH   SOLE   359,480 0 0
BRISTOL-MYERS SQUIBB CO COM 110122108 27,791 464,801 SH   SOLE   464,801 0 0
CATALENT INC COM 148806102 24,525 184,299 SH   SOLE   184,299 0 0
CENTENE CORP DEL COM 15135B101 8,792 141,107 SH   SOLE   141,107 0 0
COMMUNITY HEALTH SYS INC NEW COM 203668108 70,062 5,988,163 SH   SOLE   5,988,163 0 0
CROSS CTRY HEALTHCARE INC COM 227483104 425 20,000 SH   SOLE   20,000 0 0
CYCLERION THERAPEUTICS INC COM 23255M105 1,142 371,955 SH   SOLE   371,955 0 0
DANAHER CORPORATION COM 235851102 45,068 147,938 SH   SOLE   147,938 0 0
DEXCOM INC COM 252131107 3,500 6,401 SH   SOLE   6,401 0 0
ELEDON PHARMACEUTICALS INC COM 28617K101 705 114,008 SH   SOLE   114,008 0 0
ENSIGN GROUP INC COM 29358P101 779 10,397 SH   SOLE   10,397 0 0
ENVISTA HOLDINGS CORPORATION COM 29415F104 33,903 810,881 SH   SOLE   810,881 0 0
EVOLENT HEALTH INC CL A 30050B101 3,105 100,170 SH   SOLE   100,170 0 0
EXELIXIS INC COM 30161Q104 10,915 516,307 SH   SOLE   516,307 0 0
F-STAR THERAPEUTICS INC COM 30315R107 366 49,933 SH   SOLE   49,933 0 0
FATE THERAPEUTICS INC COM 31189P102 15,463 260,895 SH   SOLE   260,895 0 0
FREQUENCY THERAPEUTICS INC COM 35803L108 212 30,000 SH   SOLE   30,000 0 0
GLAXOSMITHKLINE PLC SPONSORED ADR 37733W105 15,410 401,654 SH   SOLE   401,654 0 0
GOHEALTH INC COM CL A 38046W105 6,346 1,261,723 SH   SOLE   1,261,723 0 0
GOSSAMER BIO INC COM 38341P102 1,884 149,910 SH   SOLE   149,910 0 0
GUARDANT HEALTH INC COM 40131M109 12,546 100,361 SH   SOLE   100,361 0 0
HCA HEALTHCARE INC COM 40412C101 9,312 38,366 SH   SOLE   38,366 0 0
HEALTHEQUITY INC COM 42226A107 7,407 114,378 SH   SOLE   114,378 0 0
HEALTHSTREAM INC COM 42222N103 2,224 77,812 SH   SOLE   77,812 0 0
HESKA CORP COM RESTRC NEW 42805E306 1,170 4,525 SH   SOLE   4,525 0 0
HILL-ROM HLDGS INC COM 431475102 4,500 30,000 SH   SOLE   30,000 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 69,522 634,670 SH   SOLE   634,670 0 0
HUMANA INC COM 444859102 9,391 24,083 SH   SOLE   24,083 0 0
ICON PLC SHS G4705A100 18,842 71,911 SH   SOLE   71,911 0 0
INTRA-CELLULAR THERAPIES INC COM 46116X101 8,602 230,744 SH   SOLE   230,744 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602 3,127 3,145 SH   SOLE   3,145 0 0
IONIS PHARMACEUTICALS INC COM 462222100 15,110 450,501 SH   SOLE   450,501 0 0
IQVIA HLDGS INC COM 46266C105 1,626 6,790 SH   SOLE   6,790 0 0
IRHYTHM TECHNOLOGIES INC COM 450056106 6,667 113,854 SH   SOLE   113,854 0 0
KARUNA THERAPEUTICS INC COM 48576A100 3,058 25,000 SH   SOLE   25,000 0 0
LABORATORY CORP AMER HLDGS COM NEW 50540R409 36,112 128,311 SH   SOLE   128,311 0 0
LEXICON PHARMACEUTICALS INC COM NEW 528872302 4,198 872,694 SH   SOLE   872,694 0 0
LIQUIDIA CORPORATION COM NEW 53635D202 2,564 929,049 SH   SOLE   929,049 0 0
LOGICBIO THERAPEUTICS INC COM 54142F102 1,603 349,919 SH   SOLE   349,919 0 0
MAGELLAN HEALTH INC COM NEW 559079207 9,899 104,700 SH   SOLE   104,700 0 0
MAGENTA THERAPEUTICS INC COM 55910K108 1,448 198,879 SH   SOLE   198,879 0 0
MARAVAI LIFESCIENCES HLDGS I COM CL A 56600D107 16,089 327,810 SH   SOLE   327,810 0 0
MASIMO CORP COM 574795100 18,138 67,000 SH   SOLE   67,000 0 0
MCKESSON CORP COM 58155Q103 32,289 161,708 SH   SOLE   161,708 0 0
MEREO BIOPHARMA GROUP PLC ADS 589492107 2,177 899,569 SH   SOLE   899,569 0 0
MILESTONE PHARMACEUTICALS IN COM 59935V107 649 113,597 SH   SOLE   113,597 0 0
MIRATI THERAPEUTICS INC COM 60468T105 1,655 9,355 SH   SOLE   9,355 0 0
MORPHIC HLDG INC COM 61775R105 2,470 43,600 SH   SOLE   43,600 0 0
MYOMO INC COM NEW 62857J201 1,784 150,000 SH   SOLE   150,000 0 0
NANOSTRING TECHNOLOGIES INC COM 63009R109 8,098 168,668 SH   SOLE   168,668 0 0
NATERA INC COM 632307104 12,502 112,189 SH   SOLE   112,189 0 0
ORCHARD THERAPEUTICS PLC ADS 68570P101 1,310 569,581 SH   SOLE   569,581 0 0
ORTHO CLINICAL DIAGNOSTICS H ORD SHS G6829J107 16,909 914,986 SH   SOLE   914,986 0 0
OUTSET MED INC COM 690145107 2,348 47,500 SH   SOLE   47,500 0 0
PERKINELMER INC COM 714046109 8,159 47,081 SH   SOLE   47,081 0 0
PHASEBIO PHARMACEUTICALS INC COM 717224109 933 300,000 SH   SOLE   300,000 0 0
PUMA BIOTECHNOLOGY INC COM 74587V107 2,790 397,940 SH   SOLE   397,940 0 0
QIAGEN NV SHS NEW N72482123 7,396 143,109 SH   SOLE   143,109 0 0
R1 RCM INC COM 749397105 16,833 764,780 SH   SOLE   764,780 0 0
REPLIGEN CORP COM 759916109 1,272 4,402 SH   SOLE   4,402 0 0
SANOFI SPONSORED ADR 80105N105 12,493 259,128 SH   SOLE   259,128 0 0
SI-BONE INC COM 825704109 3,213 150,000 SH   SOLE   150,000 0 0
SURGALIGN HOLDINGS INC COM 86882C105 3,824 3,508,536 SH   SOLE   3,508,536 0 0
TARO PHARMACEUTICAL INDS LTD SHS M8737E108 11,413 179,366 SH   SOLE   179,366 0 0
TELIGENT INC NEW COM NEW 87960W203 427 1,069,465 SH   SOLE   1,069,465 0 0
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS 881624209 34,624 3,554,804 SH   SOLE   3,554,804 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102 82,040 444,471 SH   SOLE   444,471 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104 2,632 160,000 SH   SOLE   160,000 0 0
ZOGENIX INC COM NEW 98978L204 11,766 774,591 SH   SOLE   774,591 0 0
APELLIS PHARMACEUTICALS INC CALL 03753U906 208 1,264 SH   SOLE   1,264 0 0
ASTRAZENECA PLC CALL 046353908 9,567 2,603 SH   SOLE   2,603 0 0
COMMUNITY HEALTH SYS INC NEW CALL 203668908 7,242 10,772 SH   SOLE   10,772 0 0
DECIPHERA PHARMACEUTICALS IN CALL 24344T901 447 187 SH   SOLE   187 0 0
EDITAS MEDICINE INC PUT 28106W953 1,826 500 SH   SOLE   500 0 0
FREQUENCY THERAPEUTICS INC PUT 35803L958 477 679 SH   SOLE   679 0 0
GLAXOSMITHKLINE PLC CALL 37733W905 32,681 15,037 SH   SOLE   15,037 0 0
HILL-ROM HLDGS INC CALL 431475902 3,530 294 SH   SOLE   294 0 0
HORIZON THERAPEUTICS PUB L CALL G46188901 6,199 700 SH   SOLE   700 0 0
MERCK & CO INC CALL 58933Y905 2,155 487 SH   SOLE   487 0 0
NOVAVAX INC CALL 670002901 1,601 100 SH   SOLE   100 0 0
SPDR S&P 500 ETF TR PUT 78462F953 16,344 1,000 SH   SOLE   1,000 0 0
TEVA PHARMACEUTICAL INDS LTD CALL 881624909 4,556 9,624 SH   SOLE   9,624 0 0
VERTEX PHARMACEUTICALS INC CALL 92532F900 2,743 1,733 SH   SOLE   1,733 0 0