The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
10X GENOMICS INC CL A COM 88025U109 13,750 94,450 SH   DFND 1 94,424 0 26
3-D SYS CORP DEL COM NEW 88554D205 1,360 49,326 SH   DFND 1 49,326 0 0
ABBOTT LABS COM 002824100 172,468 1,459,984 SH   DFND 1 1,380,298 0 79,686
ABBVIE INC COM 00287Y109 201,360 1,866,690 SH   DFND 1 1,851,704 0 14,986
ABM INDS INC COM 000957100 970 21,543 SH   DFND 1 21,543 0 0
ACADIA HEALTHCARE COMPANY IN COM 00404A109 72,106 1,130,534 SH   DFND 1 1,130,534 0 0
ACADIA HEALTHCARE COMPANY IN COM 00404A109 9,599 150,503 SH   OTR 2 150,503 0 0
ACADIA PHARMACEUTICALS INC COM 004225108 1,290 77,640 SH   DFND 1 77,640 0 0
ACCENTURE PLC IRELAND SHS CLASS A G1151C101 5,107 15,964 SH   DFND 1 15,964 0 0
ACCOLADE INC COM 00437E102 33,220 787,771 SH   DFND 1 787,771 0 0
ACCOLADE INC COM 00437E102 5,693 135,001 SH   OTR 2 135,001 0 0
ACV AUCTIONS INC COM CL A 00091G104 10,558 590,161 SH   DFND 1 590,161 0 0
ACV AUCTIONS INC COM CL A 00091G104 2,623 146,601 SH   OTR 2 146,601 0 0
ADECOAGRO S A COM L00849106 17,853 1,977,100 SH   DFND 1 1,977,100 0 0
ADECOAGRO S A COM L00849106 2,856 316,277 SH   OTR 2 316,277 0 0
ADOBE SYSTEMS INCORPORATED COM 00724F101 3,821,177 6,637,215 SH   DFND 1 6,394,522 0 242,693
ADOBE SYSTEMS INCORPORATED COM 00724F101 71,139 123,565 SH   OTR 2 123,565 0 0
AES CORP COM 00130H105 75,492 3,306,712 SH   DFND 1 3,306,712 0 0
AES CORP UNIT 99/99/9999 00130H204 29,881 309,964 SH   DFND 1 309,964 0 0
AFFIRM HLDGS INC COM CL A 00827B106 293,252 2,461,615 SH   DFND 1 2,461,615 0 0
AGILENT TECHNOLOGIES INC COM 00846U101 57,620 365,769 SH   DFND 1 364,221 0 1,548
AGILON HEALTH INC COM 00857U107 16,841 642,559 SH   DFND 1 642,559 0 0
AGNICO EAGLE MINES LTD COM 008474108 7,943 153,199 SH   DFND 1 153,074 0 125
AIRBNB INC COM CL A 009066101 2,256,629 13,452,335 SH   DFND 1 12,572,600 0 879,735
AIRBNB INC COM CL A 009066101 78,127 465,734 SH   OTR 2 465,734 0 0
AKOYA BIOSCIENCES INC COM 00974H104 1,538 110,183 SH   DFND 1 110,183 0 0
ALCOA CORP COM 013872106 15,962 326,158 SH   DFND 1 325,856 0 302
ALCON AG ORD SHS H01301128 63,069 775,261 SH   DFND 1 774,728 0 533
ALCON AG ORD SHS H01301128 640 7,840 SH   OTR 2 7,840 0 0
ALEXANDRIA REAL ESTATE EQ IN COM 015271109 31,045 162,479 SH   DFND 1 162,479 0 0
ALIGN TECHNOLOGY INC COM 016255101 674,771 1,014,037 SH   DFND 1 925,083 0 88,954
ALIGN TECHNOLOGY INC COM 016255101 33,912 50,963 SH   OTR 2 50,963 0 0
ALLAKOS INC COM 01671P100 17,960 169,643 SH   DFND 1 169,643 0 0
ALLEGHANY CORP MD COM 017175100 27,671 44,316 SH   DFND 1 44,316 0 0
ALLIANT ENERGY CORP COM 018802108 88,884 1,587,782 SH   DFND 1 1,587,782 0 0
ALPHABET INC CAP STK CL A 02079K305 4,514,418 1,688,567 SH   DFND 1 1,609,864 0 78,703
ALPHABET INC CAP STK CL A 02079K305 122,682 45,888 SH   OTR 2 45,888 0 0
ALPHABET INC CAP STK CL C 02079K107 3,591,929 1,347,659 SH   DFND 1 1,272,955 0 74,704
ALPHABET INC CAP STK CL C 02079K107 72,310 27,130 SH   OTR 2 27,130 0 0
ALTICE USA INC CL A 02156K103 912 44,032 SH   DFND 1 44,032 0 0
AMAZON COM INC COM 023135106 8,385,830 2,552,733 SH   DFND 1 2,434,896 0 117,837
AMAZON COM INC COM 023135106 196,041 59,677 SH   OTR 2 59,677 0 0
AMC NETWORKS INC CL A 00164V103 1,318 28,300 SH   DFND 1 28,300 0 0
AMEREN CORP COM 023608102 172,964 2,135,352 SH   DFND 1 2,135,352 0 0
AMERESCO INC CL A 02361E108 6,747 115,476 SH   DFND 1 115,369 0 107
AMERICAN ASSETS TR INC COM 024013104 16,355 437,055 SH   DFND 1 437,055 0 0
AMERICAN ASSETS TR INC COM 024013104 4,737 126,597 SH   OTR 2 126,597 0 0
AMERICAN CAMPUS CMNTYS INC COM 024835100 76,050 1,569,655 SH   DFND 1 1,569,655 0 0
AMERICAN ELEC PWR CO INC COM 025537101 64,429 793,662 SH   DFND 1 793,662 0 0
AMERICAN ELEC PWR CO INC UNIT 08/01/2021 025537127 7,180 150,622 SH   DFND 1 150,622 0 0
AMERICAN EXPRESS CO COM 025816109 4,564 27,243 SH   DFND 1 27,243 0 0
AMERICAN TOWER CORP NEW COM 03027X100 67,127 252,919 SH   DFND 1 244,511 0 8,408
AMERICAN WTR WKS CO INC NEW COM 030420103 75,774 448,260 SH   DFND 1 426,187 0 22,073
AMERIS BANCORP COM 03076K108 13,777 265,555 SH   DFND 1 265,555 0 0
AMERIS BANCORP COM 03076K108 1,840 35,463 SH   OTR 2 35,463 0 0
AMETEK INC COM 031100100 58,908 475,029 SH   DFND 1 472,946 0 2,083
AMICUS THERAPEUTICS INC COM 03152W109 50,641 5,302,782 SH   DFND 1 5,302,782 0 0
AMICUS THERAPEUTICS INC COM 03152W109 3,517 368,259 SH   OTR 2 368,259 0 0
AMN HEALTHCARE SVCS INC COM 001744101 1,807 15,744 SH   DFND 1 15,744 0 0
AMPHENOL CORP NEW CL A 032095101 55,562 758,726 SH   DFND 1 754,498 0 4,228
ANTERO MIDSTREAM CORP COM 03676B102 4,225 405,470 SH   DFND 1 405,470 0 0
AON PLC SHS CL A G0403H108 840 2,941 SH   DFND 1 2,941 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106 66,188 2,008,116 SH   DFND 1 2,008,116 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106 2,331 70,729 SH   OTR 2 70,729 0 0
APOLLO GLOBAL MGMT INC COM CL A 03768E105 64,921 1,054,082 SH   DFND 1 1,049,845 0 4,237
APPLE INC COM 037833100 6,677,417 47,190,231 SH   DFND 1 44,685,168 0 2,505,063
APPLE INC COM 037833100 177,132 1,251,814 SH   OTR 2 1,251,814 0 0
APTIV PLC SHS G6095L109 49,655 333,322 SH   DFND 1 331,633 0 1,689
ARAMARK COM 03852U106 3,149 95,831 SH   DFND 1 95,831 0 0
ARCHAEA ENERGY INC COM CL A 03940F103 4,264 225,154 SH   DFND 1 224,978 0 176
ARES MANAGEMENT CORPORATION CL A COM STK 03990B101 51,574 698,557 SH   DFND 1 695,342 0 3,215
ARGENX SE SPONSORED ADR 04016X101 249,812 827,191 SH   DFND 1 826,633 0 558
ARGENX SE SPONSORED ADR 04016X101 1,496 4,954 SH   OTR 2 4,954 0 0
ARISTA NETWORKS INC COM 040413106 844 2,456 SH   DFND 1 2,456 0 0
ARRIVAL GROUP SHS L0423Q108 7,923 602,539 SH   DFND 1 599,223 0 3,316
ARVINAS INC COM 04335A105 13,279 161,584 SH   DFND 1 161,584 0 0
ASBURY AUTOMOTIVE GROUP INC COM 043436104 1,288 6,548 SH   DFND 1 6,548 0 0
ASGN INC COM 00191U102 51,174 452,307 SH   DFND 1 452,307 0 0
ASGN INC COM 00191U102 7,889 69,728 SH   OTR 2 69,728 0 0
ASML HOLDING N V N Y REGISTRY SHS N07059210 74,857 100,464 SH   DFND 1 99,896 0 568
ASSETMARK FINL HLDGS INC COM 04546L106 12,054 484,690 SH   DFND 1 484,690 0 0
ASSETMARK FINL HLDGS INC COM 04546L106 1,760 70,753 SH   OTR 2 70,753 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108 183,112 3,048,818 SH   DFND 1 3,048,818 0 0
ATKORE INC COM 047649108 2,094 24,091 SH   DFND 1 24,091 0 0
ATLANTIC UN BANKSHARES CORP COM 04911A107 9,958 270,239 SH   DFND 1 270,239 0 0
ATLANTIC UN BANKSHARES CORP COM 04911A107 2,837 76,984 SH   OTR 2 76,984 0 0
ATLASSIAN CORP PLC CL A G06242104 2,784,552 7,113,975 SH   DFND 1 6,746,038 0 367,937
ATLASSIAN CORP PLC CL A G06242104 95,528 244,055 SH   OTR 2 244,055 0 0
AUTODESK INC COM 052769106 843 2,957 SH   DFND 1 2,957 0 0
AUTOMATIC DATA PROCESSING IN COM 053015103 1,016 5,083 SH   DFND 1 5,083 0 0
AUTOZONE INC COM 053332102 954 562 SH   DFND 1 562 0 0
AVALARA INC COM 05338G106 41,975 240,174 SH   DFND 1 238,865 0 1,309
AVALONBAY CMNTYS INC COM 053484101 20,809 93,888 SH   DFND 1 93,888 0 0
AVANGRID INC COM 05351W103 32,343 665,487 SH   DFND 1 665,487 0 0
AVANTOR INC COM 05352A100 136,464 3,336,521 SH   DFND 1 3,328,445 0 8,076
AVERY DENNISON CORP COM 053611109 20,247 97,713 SH   DFND 1 97,713 0 0
AVID BIOSERVICES INC COM 05368M106 18,214 844,415 SH   DFND 1 844,415 0 0
AVID BIOSERVICES INC COM 05368M106 4,507 208,950 SH   OTR 2 208,950 0 0
AVIENT CORPORATION COM 05368V106 68,764 1,483,585 SH   DFND 1 1,483,585 0 0
AVIENT CORPORATION COM 05368V106 9,801 211,461 SH   OTR 2 211,461 0 0
AXIS CAP HLDGS LTD SHS G0692U109 47,434 1,030,280 SH   DFND 1 1,030,280 0 0
AXIS CAP HLDGS LTD SHS G0692U109 4,910 106,637 SH   OTR 2 106,637 0 0
AXONICS INC COM 05465P101 18,539 284,820 SH   DFND 1 284,820 0 0
AXOS FINANCIAL INC COM 05465C100 2,220 43,082 SH   DFND 1 43,082 0 0
AZEK CO INC CL A 05478C105 31,976 875,333 SH   DFND 1 870,099 0 5,234
AZZ INC COM 002474104 1,332 25,033 SH   DFND 1 25,033 0 0
BALLYS CORPORATION COM 05875B106 33,226 662,671 SH   DFND 1 662,671 0 0
BALLYS CORPORATION COM 05875B106 4,497 89,686 SH   OTR 2 89,686 0 0
BANDWIDTH INC COM CL A 05988J103 33,374 369,675 SH   DFND 1 369,675 0 0
BANDWIDTH INC COM CL A 05988J103 6,691 74,116 SH   OTR 2 74,116 0 0
BANKUNITED INC COM 06652K103 49,236 1,177,344 SH   DFND 1 1,177,344 0 0
BANKUNITED INC COM 06652K103 6,339 151,569 SH   OTR 2 151,569 0 0
BARRICK GOLD CORP COM 067901108 10,486 580,955 SH   DFND 1 580,417 0 538
BEAZER HOMES USA INC COM NEW 07556Q881 1,136 65,837 SH   DFND 1 65,837 0 0
BELDEN INC COM 077454106 1,390 23,854 SH   DFND 1 23,854 0 0
BERKSHIRE HILLS BANCORP INC COM 084680107 1,551 57,497 SH   DFND 1 57,497 0 0
BHP GROUP LTD SPONSORED ADS 088606108 9,120 170,400 SH   DFND 1 170,287 0 113
BIO RAD LABS INC CL A 090572207 38,925 52,182 SH   DFND 1 52,109 0 73
BIOLIFE SOLUTIONS INC COM NEW 09062W204 10,063 237,780 SH   DFND 1 237,780 0 0
BIOLIFE SOLUTIONS INC COM NEW 09062W204 2,393 56,555 SH   OTR 2 56,555 0 0
BIONTECH SE SPONSORED ADS 09075V102 1,073,418 3,932,077 SH   DFND 1 3,719,404 0 212,673
BIONTECH SE SPONSORED ADS 09075V102 38,626 141,493 SH   OTR 2 141,493 0 0
BJS RESTAURANTS INC COM 09180C106 816 19,539 SH   DFND 1 19,539 0 0
BJS WHSL CLUB HLDGS INC COM 05550J101 29,221 532,074 SH   DFND 1 532,074 0 0
BJS WHSL CLUB HLDGS INC COM 05550J101 3,983 72,520 SH   OTR 2 72,520 0 0
BK OF AMERICA CORP COM 060505104 212,876 5,014,751 SH   DFND 1 4,951,949 0 62,802
BLACKSTONE INC COM 09260D107 108,606 933,521 SH   DFND 1 933,521 0 0
BLOCK H & R INC COM 093671105 2,079 83,157 SH   DFND 1 83,157 0 0
BLOOMIN BRANDS INC COM 094235108 51,813 2,072,501 SH   DFND 1 2,072,501 0 0
BLOOMIN BRANDS INC COM 094235108 7,225 289,016 SH   OTR 2 289,016 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 40,726 396,130 SH   DFND 1 396,130 0 0
BOOT BARN HLDGS INC COM 099406100 32,672 367,643 SH   DFND 1 367,643 0 0
BOOT BARN HLDGS INC COM 099406100 5,871 66,061 SH   OTR 2 66,061 0 0
BRIDGE INVT GROUP HLDGS INC COM CL A 10806B100 28,547 1,615,595 SH   DFND 1 1,615,595 0 0
BRIDGE INVT GROUP HLDGS INC COM CL A 10806B100 3,910 221,261 SH   OTR 2 221,261 0 0
BRIGHTSPHERE INVT GROUP INC COM 10948W103 84,381 3,229,276 SH   DFND 1 3,229,276 0 0
BRIGHTSPHERE INVT GROUP INC COM 10948W103 10,798 413,248 SH   OTR 2 413,248 0 0
BRISTOL-MYERS SQUIBB CO COM 110122108 107,008 1,808,487 SH   DFND 1 1,808,487 0 0
BROADCOM INC COM 11135F101 185,465 382,457 SH   DFND 1 378,978 0 3,479
BROOKLINE BANCORP INC DEL COM 11373M107 18,601 1,218,895 SH   DFND 1 1,218,895 0 0
BROOKLINE BANCORP INC DEL COM 11373M107 5,423 355,390 SH   OTR 2 355,390 0 0
BROOKS AUTOMATION INC NEW COM 114340102 46,105 450,467 SH   DFND 1 450,467 0 0
BROOKS AUTOMATION INC NEW COM 114340102 8,765 85,637 SH   OTR 2 85,637 0 0
BRUNSWICK CORP COM 117043109 84,657 888,595 SH   DFND 1 888,595 0 0
BRUNSWICK CORP COM 117043109 9,555 100,299 SH   OTR 2 100,299 0 0
BUCKLE INC COM 118440106 1,153 29,129 SH   DFND 1 29,129 0 0
BUMBLE INC COM CL A 12047B105 73,845 1,477,494 SH   DFND 1 1,477,494 0 0
BUNGE LIMITED COM G16962105 10,630 130,724 SH   DFND 1 130,615 0 109
BURLINGTON STORES INC COM 122017106 62,485 220,350 SH   DFND 1 219,172 0 1,178
BURNING ROCK BIOTECH LTD SPONSORED ADS 12233L107 10,152 567,783 SH   DFND 1 567,783 0 0
C4 THERAPEUTICS INC COM STK 12529R107 19,664 440,102 SH   DFND 1 440,102 0 0
C4 THERAPEUTICS INC COM STK 12529R107 2,020 45,211 SH   OTR 2 45,211 0 0
CACTUS INC CL A 127203107 31,041 822,940 SH   DFND 1 822,747 0 193
CACTUS INC CL A 127203107 5,578 147,874 SH   OTR 2 147,874 0 0
CAESARS ENTERTAINMENT INC NE COM 12769G100 1,846 16,444 SH   DFND 1 16,444 0 0
CALIFORNIA WTR SVC GROUP COM 130788102 971 16,471 SH   DFND 1 16,471 0 0
CANADIAN NATL RY CO COM 136375102 22,720 196,452 SH   DFND 1 156,565 0 39,887
CAPITAL ONE FINL CORP COM 14040H105 168,256 1,038,810 SH   DFND 1 1,038,810 0 0
CARDLYTICS INC COM 14161W105 12,858 153,179 SH   DFND 1 153,179 0 0
CARDLYTICS INC COM 14161W105 3,375 40,206 SH   OTR 2 40,206 0 0
CARIBOU BIOSCIENCES INC COM 142038108 7,688 322,091 SH   DFND 1 322,091 0 0
CARVANA CO CL A 146869102 1,163,302 3,857,868 SH   DFND 1 3,691,528 0 166,340
CARVANA CO CL A 146869102 23,425 77,686 SH   OTR 2 77,686 0 0
CATALENT INC COM 148806102 66,002 495,995 SH   DFND 1 493,846 0 2,149
CATERPILLAR INC COM 149123101 29,259 152,414 SH   DFND 1 152,414 0 0
CBRE GROUP INC CL A 12504L109 68,936 708,050 SH   DFND 1 704,903 0 3,147
CDW CORP COM 12514G108 836 4,594 SH   DFND 1 4,571 0 23
CENTERPOINT ENERGY INC COM 15189T107 153,334 6,233,087 SH   DFND 1 6,016,045 0 217,042
CENTESSA PHARMACEUTICALS PLC SPONSORED ADS 152309100 4,951 296,456 SH   DFND 1 296,456 0 0
CENTURY CMNTYS INC COM 156504300 46,065 749,636 SH   DFND 1 749,636 0 0
CENTURY CMNTYS INC COM 156504300 7,299 118,778 SH   OTR 2 118,778 0 0
CHAMPIONX CORPORATION COM 15872M104 806 36,068 SH   DFND 1 36,068 0 0
CHART INDS INC COM 16115Q308 21,231 111,094 SH   DFND 1 110,983 0 111
CHENIERE ENERGY INC COM NEW 16411R208 222,363 2,276,675 SH   DFND 1 2,193,263 0 83,412
CHEVRON CORP NEW COM 166764100 143,004 1,409,605 SH   DFND 1 1,393,090 0 16,515
CHEWY INC CL A 16679L109 37,575 551,685 SH   DFND 1 326,446 0 225,239
CHIPOTLE MEXICAN GRILL INC COM 169656105 1,295,497 712,783 SH   DFND 1 670,120 0 42,663
CHIPOTLE MEXICAN GRILL INC COM 169656105 28,824 15,859 SH   OTR 2 15,859 0 0
CHUBB LIMITED COM H1467J104 217,469 1,253,566 SH   DFND 1 1,253,566 0 0
CIENA CORP COM NEW 171779309 17,243 335,786 SH   DFND 1 335,786 0 0
CIGNA CORP NEW COM 125523100 71,364 356,535 SH   DFND 1 356,535 0 0
CIMAREX ENERGY CO COM 171798101 10,980 125,919 SH   DFND 1 125,803 0 116
CISCO SYS INC COM 17275R102 102,102 1,875,833 SH   DFND 1 1,840,094 0 35,739
CITI TRENDS INC COM 17306X102 27,282 373,940 SH   DFND 1 373,940 0 0
CITI TRENDS INC COM 17306X102 3,778 51,777 SH   OTR 2 51,777 0 0
CITIGROUP INC COM NEW 172967424 126,461 1,801,953 SH   DFND 1 1,801,953 0 0
CLEAR SECURE INC COM CL A 18467V109 25,724 626,653 SH   DFND 1 625,099 0 1,554
CLEAR SECURE INC COM CL A 18467V109 2,381 58,001 SH   OTR 2 58,001 0 0
CLEARWATER ANALYTICS HLDGS I CL A 185123106 12,106 472,713 SH   DFND 1 472,713 0 0
CLEARWATER ANALYTICS HLDGS I CL A 185123106 1,837 71,721 SH   OTR 2 71,721 0 0
CMS ENERGY CORP COM 125896100 124,742 2,088,435 SH   DFND 1 2,025,694 0 62,741
CNO FINL GROUP INC COM 12621E103 1,809 76,850 SH   DFND 1 76,850 0 0
COGNEX CORP COM 192422103 61,002 760,428 SH   DFND 1 757,565 0 2,863
COHU INC COM 192576106 1,290 40,392 SH   DFND 1 40,392 0 0
COLFAX CORP COM 194014106 60,624 1,320,793 SH   DFND 1 1,320,793 0 0
COLFAX CORP COM 194014106 8,586 187,048 SH   OTR 2 187,048 0 0
COMCAST CORP NEW CL A 20030N101 56,732 1,014,348 SH   DFND 1 975,503 0 38,845
COMMERCIAL METALS CO COM 201723103 1,727 56,712 SH   DFND 1 56,712 0 0
COMMUNITY HEALTH SYS INC NEW COM 203668108 938 80,204 SH   DFND 1 80,204 0 0
CONCRETE PUMPING HLDGS INC COM 206704108 9,371 1,097,226 SH   DFND 1 1,097,226 0 0
CONCRETE PUMPING HLDGS INC COM 206704108 2,711 317,496 SH   OTR 2 317,496 0 0
CONOCOPHILLIPS COM 20825C104 407,241 6,009,158 SH   DFND 1 6,008,656 0 502
CONSTELLIUM SE CL A SHS F21107101 18,166 967,305 SH   DFND 1 966,499 0 806
COOPER COS INC COM NEW 216648402 42,193 102,085 SH   DFND 1 101,597 0 488
CORE & MAIN INC CL A 21874C102 27,323 1,042,445 SH   DFND 1 1,042,445 0 0
CORE & MAIN INC CL A 21874C102 3,760 143,471 SH   OTR 2 143,471 0 0
CORNING INC COM 219350105 20,593 564,339 SH   DFND 1 564,339 0 0
COSTAR GROUP INC COM 22160N109 88,306 1,026,095 SH   DFND 1 860,424 0 165,671
COSTAR GROUP INC COM 22160N109 3,859 44,846 SH   OTR 2 44,846 0 0
COSTCO WHSL CORP NEW COM 22160K105 1,471,439 3,274,593 SH   DFND 1 3,129,806 0 144,787
COSTCO WHSL CORP NEW COM 22160K105 27,354 60,875 SH   OTR 2 60,875 0 0
COUPANG INC CL A 22266T109 16,785 602,677 SH   DFND 1 602,677 0 0
COUSINS PPTYS INC COM NEW 222795502 49,128 1,317,451 SH   DFND 1 1,317,451 0 0
COUSINS PPTYS INC COM NEW 222795502 5,715 153,265 SH   OTR 2 153,265 0 0
COVETRUS INC COM 22304C100 8,451 465,856 SH   DFND 1 465,856 0 0
COVETRUS INC COM 22304C100 2,485 136,992 SH   OTR 2 136,992 0 0
CRESTWOOD EQUITY PARTNERS LP UNIT LTD PARTNER 226344208 3,669 129,278 SH   DFND 1 129,278 0 0
CRISPR THERAPEUTICS AG NAMEN AKT H17182108 46,673 416,980 SH   DFND 1 416,980 0 0
CROCS INC COM 227046109 905 6,306 SH   DFND 1 6,306 0 0
CROWDSTRIKE HLDGS INC CL A 22788C105 2,147,167 8,736,133 SH   DFND 1 8,235,154 0 500,979
CROWDSTRIKE HLDGS INC CL A 22788C105 63,322 257,636 SH   OTR 2 257,636 0 0
CROWN CASTLE INTL CORP NEW COM 22822V101 19,914 114,899 SH   DFND 1 110,683 0 4,216
CROWN HLDGS INC COM 228368106 186,684 1,852,389 SH   DFND 1 1,849,747 0 2,642
CURTISS WRIGHT CORP COM 231561101 15,028 119,101 SH   DFND 1 119,101 0 0
CURTISS WRIGHT CORP COM 231561101 2,055 16,288 SH   OTR 2 16,288 0 0
D R HORTON INC COM 23331A109 95,739 1,140,161 SH   DFND 1 1,140,161 0 0
DANAHER CORPORATION COM 235851102 1,581,188 5,193,758 SH   DFND 1 4,904,818 0 288,940
DANAHER CORPORATION COM 235851102 31,849 104,615 SH   OTR 2 104,615 0 0
DARDEN RESTAURANTS INC COM 237194105 22,240 146,826 SH   DFND 1 146,826 0 0
DARLING INGREDIENTS INC COM 237266101 49,450 687,754 SH   DFND 1 687,567 0 187
DAVITA INC COM 23918K108 815 7,009 SH   DFND 1 7,009 0 0
DCP MIDSTREAM LP COM UT LTD PTN 23311P100 26,440 936,597 SH   DFND 1 936,597 0 0
DEERE & CO COM 244199105 66,725 199,137 SH   DFND 1 199,137 0 0
DEFINITIVE HEALTHCARE CORP CLASS A COM 24477E103 12,545 292,892 SH   DFND 1 292,892 0 0
DEFINITIVE HEALTHCARE CORP CLASS A COM 24477E103 796 18,589 SH   OTR 2 18,589 0 0
DELL TECHNOLOGIES INC CL C 24703L202 2,791 26,822 SH   DFND 1 26,822 0 0
DELTA AIR LINES INC DEL COM NEW 247361702 88,708 2,081,870 SH   DFND 1 2,081,870 0 0
DENALI THERAPEUTICS INC COM 24823R105 11,524 228,422 SH   DFND 1 228,422 0 0
DESCARTES SYS GROUP INC COM 249906108 25,056 308,346 SH   DFND 1 308,346 0 0
DESCARTES SYS GROUP INC COM 249906108 4,166 51,268 SH   OTR 2 51,268 0 0
DEVON ENERGY CORP NEW COM 25179M103 73,562 2,071,588 SH   DFND 1 2,070,800 0 788
DEXCOM INC COM 252131107 824,554 1,507,797 SH   DFND 1 1,409,640 0 98,157
DEXCOM INC COM 252131107 19,720 36,060 SH   OTR 2 36,060 0 0
DIAGEO PLC SPON ADR NEW 25243Q205 13,980 72,437 SH   DFND 1 72,437 0 0
DIAMONDBACK ENERGY INC COM 25278X109 26,453 279,427 SH   DFND 1 279,182 0 245
DIAMONDROCK HOSPITALITY CO COM 252784301 1,193 126,207 SH   DFND 1 126,207 0 0
DIGITALBRIDGE GROUP INC CL A COM 25401T108 835 138,418 SH   DFND 1 138,418 0 0
DISNEY WALT CO COM 254687106 148,107 875,492 SH   DFND 1 860,081 0 15,411
DLOCAL LTD CLASS A COM G29018101 270,915 4,965,462 SH   DFND 1 4,575,972 0 389,490
DLOCAL LTD CLASS A COM G29018101 13,847 253,787 SH   OTR 2 253,787 0 0
DOCUSIGN INC COM 256163106 1,427,534 5,545,331 SH   DFND 1 5,161,181 0 384,150
DOCUSIGN INC COM 256163106 55,865 217,010 SH   OTR 2 217,010 0 0
DOMINION ENERGY INC COM 25746U109 345,620 4,733,229 SH   DFND 1 4,684,790 0 48,439
DOVER CORP COM 260003108 1,032 6,639 SH   DFND 1 6,639 0 0
DOW INC COM 260557103 78,444 1,362,827 SH   DFND 1 1,362,827 0 0
DT MIDSTREAM INC COMMON STOCK 23345M107 80,472 1,740,320 SH   DFND 1 1,649,984 0 90,336
DTE ENERGY CO COM 233331107 95,676 856,469 SH   DFND 1 856,469 0 0
DUKE ENERGY CORP NEW COM NEW 26441C204 96,517 989,005 SH   DFND 1 989,005 0 0
DYNATRACE INC COM NEW 268150109 462,327 6,514,410 SH   DFND 1 5,595,903 0 918,507
DYNATRACE INC COM NEW 268150109 39,030 549,948 SH   OTR 2 549,948 0 0
E L F BEAUTY INC COM 26856L103 33,445 1,151,295 SH   DFND 1 1,151,295 0 0
E L F BEAUTY INC COM 26856L103 8,781 302,260 SH   OTR 2 302,260 0 0
EAST WEST BANCORP INC COM 27579R104 39,036 503,430 SH   DFND 1 503,430 0 0
EASTERN BANKSHARES INC COM 27627N105 23,442 1,154,792 SH   DFND 1 1,154,792 0 0
EASTERN BANKSHARES INC COM 27627N105 3,101 152,760 SH   OTR 2 152,760 0 0
EBAY INC. COM 278642103 3,261 46,812 SH   DFND 1 46,812 0 0
EDISON INTL COM 281020107 32,940 593,833 SH   DFND 1 593,833 0 0
ELECTRIC LAST MILE SOLUTNS I CLASS A COM 28489L104 5,812 786,524 SH   DFND 1 786,524 0 0
EMERSON ELEC CO COM 291011104 50,961 540,992 SH   DFND 1 540,992 0 0
ENBRIDGE INC COM 29250N105 56,573 1,421,550 SH   DFND 1 1,360,087 0 61,463
ENCORE WIRE CORP COM 292562105 2,053 21,648 SH   DFND 1 21,648 0 0
ENDAVA PLC ADS 29260V105 996 7,332 SH   DFND 1 7,332 0 0
ENERGY TRANSFER L P COM UT LTD PTN 29273V100 37,475 3,911,748 SH   DFND 1 3,911,748 0 0
ENERPAC TOOL GROUP CORP CL A COM 292765104 33,518 1,616,901 SH   DFND 1 1,616,901 0 0
ENERPAC TOOL GROUP CORP CL A COM 292765104 5,206 251,117 SH   OTR 2 251,117 0 0
ENPHASE ENERGY INC COM 29355A107 45,954 306,422 SH   DFND 1 305,004 0 1,418
ENSIGN GROUP INC COM 29358P101 1,164 15,546 SH   DFND 1 15,546 0 0
ENTEGRIS INC COM 29362U104 58,066 461,207 SH   DFND 1 459,525 0 1,682
ENTERGY CORP NEW COM 29364G103 69,520 700,032 SH   DFND 1 700,032 0 0
ENTERPRISE FINL SVCS CORP COM 293712105 32,379 715,081 SH   DFND 1 715,081 0 0
ENTERPRISE FINL SVCS CORP COM 293712105 5,183 114,460 SH   OTR 2 114,460 0 0
ENTERPRISE PRODS PARTNERS L COM 293792107 21,584 997,410 SH   DFND 1 997,410 0 0
EPAM SYS INC COM 29414B104 927 1,625 SH   DFND 1 1,625 0 0
EQT CORP COM 26884L109 18,628 910,453 SH   DFND 1 909,642 0 811
EQUINIX INC COM 29444U700 40,271 50,968 SH   DFND 1 48,846 0 2,122
EQUITABLE HLDGS INC COM 29452E101 752 25,361 SH   DFND 1 25,361 0 0
EQUITRANS MIDSTREAM CORP COM 294600101 9,501 936,989 SH   DFND 1 936,989 0 0
ERO COPPER CORP COM 296006109 25,168 1,420,854 SH   DFND 1 1,420,854 0 0
ESSENTIAL UTILS INC COM 29670G102 108,066 2,345,183 SH   DFND 1 2,297,480 0 47,703
ETHAN ALLEN INTERIORS INC COM 297602104 1,265 53,391 SH   DFND 1 53,391 0 0
ETSY INC COM 29786A106 48,840 234,853 SH   DFND 1 233,586 0 1,267
EVERBRIDGE INC COM 29978A104 49,852 330,057 SH   DFND 1 330,057 0 0
EVERBRIDGE INC COM 29978A104 8,864 58,686 SH   OTR 2 58,686 0 0
EVERGY INC COM 30034W106 91,083 1,464,361 SH   DFND 1 1,464,361 0 0
EVERSOURCE ENERGY COM 30040W108 49,814 609,270 SH   DFND 1 566,507 0 42,763
EVERTEC INC COM 30040P103 2,075 45,382 SH   DFND 1 45,382 0 0
EVO PMTS INC CL A COM 26927E104 31,846 1,344,830 SH   DFND 1 1,344,830 0 0
EVO PMTS INC CL A COM 26927E104 6,158 260,066 SH   OTR 2 260,066 0 0
EXACT SCIENCES CORP COM 30063P105 15,246 159,731 SH   DFND 1 158,651 0 1,080
EXELON CORP COM 30161N101 74,515 1,541,468 SH   DFND 1 1,474,371 0 67,097
EXLSERVICE HOLDINGS INC COM 302081104 1,997 16,224 SH   DFND 1 16,224 0 0
EXXON MOBIL CORP COM 30231G102 4,315 73,357 SH   DFND 1 37,455 0 35,902
FACEBOOK INC CL A 30303M102 4,146,173 12,216,546 SH   DFND 1 11,673,397 0 543,149
FACEBOOK INC CL A 30303M102 80,913 238,406 SH   OTR 2 238,406 0 0
FARO TECHNOLOGIES INC COM 311642102 9,867 149,935 SH   DFND 1 149,935 0 0
FARO TECHNOLOGIES INC COM 311642102 2,876 43,701 SH   OTR 2 43,701 0 0
FATE THERAPEUTICS INC COM 31189P102 22,743 383,714 SH   DFND 1 383,714 0 0
FEDEX CORP COM 31428X106 60,620 276,436 SH   DFND 1 276,436 0 0
FERRARI N V COM N3167Y103 38,596 184,563 SH   DFND 1 183,243 0 1,320
FIRST BANCORP N C COM 318910106 34,053 791,744 SH   DFND 1 791,744 0 0
FIRST BANCORP N C COM 318910106 5,516 128,254 SH   OTR 2 128,254 0 0
FIRST BANCORP P R COM NEW 318672706 1,124 85,443 SH   DFND 1 85,443 0 0
FIRST FNDTN INC COM 32026V104 22,418 852,379 SH   DFND 1 852,379 0 0
FIRST FNDTN INC COM 32026V104 5,361 203,839 SH   OTR 2 203,839 0 0
FIRST SOLAR INC COM 336433107 4,628 48,485 SH   DFND 1 48,447 0 38
FIRSTENERGY CORP COM 337932107 1,003 28,155 SH   DFND 1 28,155 0 0
FIRSTSERVICE CORP NEW COM 33767E202 1,679 9,295 SH   DFND 1 9,295 0 0
FIVE BELOW INC COM 33829M101 79,054 447,114 SH   DFND 1 445,625 0 1,489
FIVE9 INC COM 338307101 31,297 195,927 SH   DFND 1 194,778 0 1,149
FLOOR & DECOR HLDGS INC CL A 339750101 970 8,028 SH   DFND 1 8,028 0 0
FLYWIRE CORPORATION COM VTG 302492103 15,893 362,536 SH   DFND 1 362,536 0 0
FLYWIRE CORPORATION COM VTG 302492103 2,256 51,458 SH   OTR 2 51,458 0 0
FOCUS FINL PARTNERS INC COM CL A 34417P100 67,239 1,283,910 SH   DFND 1 1,283,910 0 0
FOCUS FINL PARTNERS INC COM CL A 34417P100 9,059 172,985 SH   OTR 2 172,985 0 0
FORTINET INC COM 34959E109 3,001 10,277 SH   DFND 1 10,277 0 0
FORTIVE CORP COM 34959J108 76,744 1,087,482 SH   DFND 1 1,087,482 0 0
FREEPORT-MCMORAN INC CL B 35671D857 26,271 807,603 SH   DFND 1 807,048 0 555
FRESHPET INC COM 358039105 68,622 480,912 SH   DFND 1 479,337 0 1,575
FRESHPET INC COM 358039105 5,917 41,470 SH   OTR 2 41,470 0 0
FRESHWORKS INC CLASS A COM 358054104 13,277 310,998 SH   DFND 1 310,998 0 0
FREYR BATTERY SHS L4135L100 6,832 692,239 SH   DFND 1 691,630 0 609
FULTON FINL CORP PA COM 360271100 2,372 155,259 SH   DFND 1 155,259 0 0
GAMING & LEISURE PPTYS INC COM 36467J108 42,809 924,203 SH   DFND 1 924,203 0 0
GARTNER INC COM 366651107 63,214 208,024 SH   DFND 1 207,154 0 870
GATES INDUSTRIAL CORPRATIN P ORD SHS G39108108 36,899 2,267,914 SH   DFND 1 2,267,914 0 0
GATES INDUSTRIAL CORPRATIN P ORD SHS G39108108 4,532 278,529 SH   OTR 2 278,529 0 0
GENERAC HLDGS INC COM 368736104 1,046 2,560 SH   DFND 1 2,560 0 0
GENERAL ELECTRIC CO COM NEW 369604301 92,711 899,843 SH   DFND 1 899,843 0 0
GENERAL MTRS CO COM 37045V100 176,404 3,346,688 SH   DFND 1 3,346,688 0 0
GENESIS ENERGY L P UNIT LTD PARTN 371927104 4,009 402,086 SH   DFND 1 402,086 0 0
GENETRON HLDGS LTD ADS 37186H100 17,671 1,275,876 SH   DFND 1 1,275,876 0 0
GFL ENVIRONMENTAL INC SUB VTG SHS 36168Q104 76,166 2,050,225 SH   DFND 1 2,043,374 0 6,851
GFL ENVIRONMENTAL INC UNIT 99/99/9999T 36168Q120 29,051 341,616 SH   DFND 1 284,829 0 56,787
GLOBALSTAR INC COM 378973408 711 425,741 SH   DFND 1 425,741 0 0
GLOBANT S A COM L44385109 234,298 833,773 SH   DFND 1 832,786 0 987
GLOBANT S A COM L44385109 1,560 5,550 SH   OTR 2 5,550 0 0
GOLDMAN SACHS GROUP INC COM 38141G104 899,799 2,380,231 SH   DFND 1 2,244,751 0 135,480
GOLDMAN SACHS GROUP INC COM 38141G104 19,478 51,526 SH   OTR 2 51,526 0 0
GOOSEHEAD INS INC COM CL A 38267D109 20,008 131,382 SH   DFND 1 131,382 0 0
GOOSEHEAD INS INC COM CL A 38267D109 5,042 33,107 SH   OTR 2 33,107 0 0
GRAPHITE BIO INC COM 38870X104 4,858 296,375 SH   DFND 1 296,375 0 0
GRAY TELEVISION INC COM 389375106 2,000 87,654 SH   DFND 1 87,654 0 0
GREAT LAKES DREDGE & DOCK CO COM 390607109 69,322 4,593,884 SH   DFND 1 4,593,884 0 0
GREAT LAKES DREDGE & DOCK CO COM 390607109 9,154 606,623 SH   OTR 2 606,623 0 0
GRID DYNAMICS HLDGS INC CL A 39813G109 37,034 1,267,416 SH   DFND 1 1,267,416 0 0
GRID DYNAMICS HLDGS INC CL A 39813G109 9,617 329,129 SH   OTR 2 329,129 0 0
GUARDANT HEALTH INC COM 40131M109 84,625 676,944 SH   DFND 1 668,364 0 8,580
HALLIBURTON CO COM 406216101 10,326 477,635 SH   DFND 1 477,231 0 404
HAMILTON LANE INC CL A 407497106 14,363 169,337 SH   DFND 1 169,337 0 0
HAMILTON LANE INC CL A 407497106 4,105 48,394 SH   OTR 2 48,394 0 0
HANNON ARMSTRONG SUST INFR C COM 41068X100 7,140 133,512 SH   DFND 1 133,395 0 117
HARSCO CORP COM 415864107 40,575 2,393,805 SH   DFND 1 2,393,805 0 0
HARSCO CORP COM 415864107 5,781 341,063 SH   OTR 2 341,063 0 0
HAWAIIAN HOLDINGS INC COM 419879101 2,213 102,164 SH   DFND 1 102,164 0 0
HCA HEALTHCARE INC COM 40412C101 1,581 6,515 SH   DFND 1 6,515 0 0
HDFC BANK LTD SPONSORED ADS 40415F101 41,664 570,041 SH   DFND 1 570,041 0 0
HEALTHEQUITY INC COM 42226A107 10,569 163,189 SH   DFND 1 163,189 0 0
HEALTHEQUITY INC COM 42226A107 2,797 43,197 SH   OTR 2 43,197 0 0
HEICO CORP NEW COM 422806109 37,929 287,625 SH   DFND 1 286,166 0 1,459
HENRY JACK & ASSOC INC COM 426281101 27,813 169,532 SH   DFND 1 168,613 0 919
HERC HLDGS INC COM 42704L104 1,482 9,067 SH   DFND 1 9,067 0 0
HERSHEY CO COM 427866108 21,209 125,313 SH   DFND 1 125,313 0 0
HESS CORP COM 42809H107 28,202 361,056 SH   DFND 1 360,768 0 288
HESS MIDSTREAM LP CL A SHS 428103105 4,560 161,628 SH   DFND 1 161,628 0 0
HEXCEL CORP NEW COM 428291108 345 5,811 SH   DFND 1 5,811 0 0
HILLTOP HOLDINGS INC COM 432748101 974 29,809 SH   DFND 1 29,809 0 0
HILTON WORLDWIDE HLDGS INC COM 43300A203 52,964 400,909 SH   DFND 1 398,858 0 2,051
HOLOGIC INC COM 436440101 49,902 676,089 SH   DFND 1 676,089 0 0
HOME DEPOT INC COM 437076102 1,266,250 3,857,462 SH   DFND 1 3,553,290 0 304,172
HOME DEPOT INC COM 437076102 41,327 125,896 SH   OTR 2 125,896 0 0
HONEYWELL INTL INC COM 438516106 8,007 37,721 SH   DFND 1 37,721 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 104,933 957,944 SH   DFND 1 954,892 0 3,052
HOULIHAN LOKEY INC CL A 441593100 31,137 338,083 SH   DFND 1 338,083 0 0
HOULIHAN LOKEY INC CL A 441593100 7,570 82,191 SH   OTR 2 82,191 0 0
HOWARD HUGHES CORP COM 44267D107 18,635 212,220 SH   DFND 1 212,220 0 0
HP INC COM 40434L105 2,448 89,477 SH   DFND 1 89,477 0 0
HUBSPOT INC COM 443573100 1,084,092 1,603,473 SH   DFND 1 1,472,080 0 131,393
HUBSPOT INC COM 443573100 53,651 79,355 SH   OTR 2 79,355 0 0
HUMANA INC COM 444859102 323,405 831,055 SH   DFND 1 758,050 0 73,005
HUMANA INC COM 444859102 7,056 18,131 SH   OTR 2 18,131 0 0
HUNT J B TRANS SVCS INC COM 445658107 64,137 383,551 SH   DFND 1 382,038 0 1,513
HURON CONSULTING GROUP INC COM 447462102 16,943 325,821 SH   DFND 1 325,821 0 0
HURON CONSULTING GROUP INC COM 447462102 4,852 93,307 SH   OTR 2 93,307 0 0
I MAB SPONSORED ADS 44975P103 12,068 166,485 SH   DFND 1 166,485 0 0
IAA INC COM 449253103 24,968 457,533 SH   DFND 1 455,157 0 2,376
ILLUMINA INC COM 452327109 32,948 81,231 SH   DFND 1 81,231 0 0
IMMATICS N.V *W EXP 07/01/202 N44445117 1,633 386,035 SH   DFND 1 386,035 0 0
INARI MED INC COM 45332Y109 18,861 232,559 SH   DFND 1 232,559 0 0
INARI MED INC COM 45332Y109 3,468 42,768 SH   OTR 2 42,768 0 0
INDEPENDENCE RLTY TR INC COM 45378A106 65,003 3,194,244 SH   DFND 1 3,194,244 0 0
INDEPENDENCE RLTY TR INC COM 45378A106 9,149 449,594 SH   OTR 2 449,594 0 0
INNOVIVA INC COM 45781M101 1,243 74,416 SH   DFND 1 74,416 0 0
INSPIRE MED SYS INC COM 457730109 29,434 126,392 SH   DFND 1 126,392 0 0
INSPIRE MED SYS INC COM 457730109 7,465 32,053 SH   OTR 2 32,053 0 0
INTAPP INC COM 45827U109 11,910 462,352 SH   DFND 1 462,352 0 0
INTAPP INC COM 45827U109 1,801 69,919 SH   OTR 2 69,919 0 0
INTEGRA LIFESCIENCES HLDGS C COM NEW 457985208 8,321 121,502 SH   DFND 1 121,502 0 0
INTEGRA LIFESCIENCES HLDGS C COM NEW 457985208 1,949 28,463 SH   OTR 2 28,463 0 0
INTELLIA THERAPEUTICS INC COM 45826J105 123,227 918,577 SH   DFND 1 918,014 0 563
INTERNATIONAL BANCSHARES COR COM 459044103 2,023 48,587 SH   DFND 1 48,587 0 0
INTUIT COM 461202103 13,221 24,505 SH   DFND 1 24,505 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602 794,164 798,837 SH   DFND 1 749,649 0 49,188
INTUITIVE SURGICAL INC COM NEW 46120E602 17,185 17,286 SH   OTR 2 17,286 0 0
IQVIA HLDGS INC COM 46266C105 117,481 490,444 SH   DFND 1 489,338 0 1,106
IRONWOOD PHARMACEUTICALS INC COM CL A 46333X108 2,307 176,657 SH   DFND 1 176,657 0 0
ISHARES TR MSCI ACWI ETF 464288257 4,149 41,528 SH   DFND 1 40,994 0 534
ISHARES TR MSCI ACWI EX US 464288240 2,633 47,521 SH   DFND 1 47,435 0 86
ISHARES TR NORTH AMERN NAT 464287374 641 21,808 SH   DFND 1 21,365 0 443
ISHARES TR RUS 1000 GRW ETF 464287614 3,313 12,088 SH   DFND 1 10,276 0 1,812
J2 GLOBAL INC COM 48123V102 2,257 16,517 SH   DFND 1 16,517 0 0
JACK IN THE BOX INC COM 466367109 40,860 419,811 SH   DFND 1 419,811 0 0
JACK IN THE BOX INC COM 466367109 7,205 74,027 SH   OTR 2 74,027 0 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105 13,697 105,190 SH   DFND 1 105,190 0 0
JD.COM INC SPON ADR CL A 47215P106 22,396 310,027 SH   DFND 1 310,027 0 0
JELD-WEN HLDG INC COM 47580P103 50,093 2,001,315 SH   DFND 1 2,001,315 0 0
JELD-WEN HLDG INC COM 47580P103 7,046 281,509 SH   OTR 2 281,509 0 0
JOHNSON CTLS INTL PLC SHS G51502105 236,992 3,481,077 SH   DFND 1 3,481,077 0 0
JPMORGAN CHASE & CO COM 46625H100 363,748 2,222,177 SH   DFND 1 2,196,836 0 25,341
KANSAS CITY SOUTHERN COM NEW 485170302 1,585 5,855 SH   DFND 1 1,407 0 4,448
KARUNA THERAPEUTICS INC COM 48576A100 10,807 88,341 SH   DFND 1 88,341 0 0
KARYOPHARM THERAPEUTICS INC COM 48576U106 1,572 270,092 SH   DFND 1 270,092 0 0
KB HOME COM 48666K109 1,501 38,568 SH   DFND 1 38,568 0 0
KENNAMETAL INC COM 489170100 16,709 488,147 SH   DFND 1 488,147 0 0
KENNAMETAL INC COM 489170100 4,895 143,001 SH   OTR 2 143,001 0 0
KENNEDY-WILSON HOLDINGS INC COM 489398107 2,452 117,217 SH   DFND 1 117,217 0 0
KEYSIGHT TECHNOLOGIES INC COM 49338L103 1,248 7,598 SH   DFND 1 7,598 0 0
KFORCE INC COM 493732101 1,812 30,381 SH   DFND 1 30,381 0 0
KINDER MORGAN INC DEL COM 49456B101 8,323 497,502 SH   DFND 1 497,502 0 0
KINROSS GOLD CORP COM 496902404 7,369 1,374,781 SH   DFND 1 1,373,646 0 1,135
KITE RLTY GROUP TR COM NEW 49803T300 941 46,219 SH   DFND 1 46,219 0 0
KKR & CO INC COM 48251W104 20,359 334,416 SH   DFND 1 334,416 0 0
KNIGHT-SWIFT TRANSN HLDGS IN CL A 499049104 763 14,918 SH   DFND 1 14,918 0 0
KONTOOR BRANDS INC COM 50050N103 52,261 1,046,266 SH   DFND 1 1,046,266 0 0
KONTOOR BRANDS INC COM 50050N103 7,986 159,880 SH   OTR 2 159,880 0 0
KORN FERRY COM NEW 500643200 1,338 18,487 SH   DFND 1 18,487 0 0
KOSMOS ENERGY LTD COM 500688106 1,206 407,507 SH   DFND 1 407,507 0 0
KRAFT HEINZ CO COM 500754106 357 9,692 SH   DFND 1 9,692 0 0
KULICKE & SOFFA INDS INC COM 501242101 1,063 18,236 SH   DFND 1 18,236 0 0
KYMERA THERAPEUTICS INC COM 501575104 10,842 184,581 SH   DFND 1 184,581 0 0
L3HARRIS TECHNOLOGIES INC COM 502431109 37,421 169,912 SH   DFND 1 168,924 0 988
LABORATORY CORP AMER HLDGS COM NEW 50540R409 131,661 467,813 SH   DFND 1 467,813 0 0
LAM RESEARCH CORP COM 512807108 129,647 227,791 SH   DFND 1 227,779 0 12
LATCH INC COM 51818V106 727 64,546 SH   DFND 1 64,546 0 0
LATTICE SEMICONDUCTOR CORP COM 518415104 9,408 145,521 SH   DFND 1 145,521 0 0
LATTICE SEMICONDUCTOR CORP COM 518415104 2,005 31,007 SH   OTR 2 31,007 0 0
LAUDER ESTEE COS INC CL A 518439104 2,102,194 7,008,949 SH   DFND 1 6,701,383 0 307,566
LAUDER ESTEE COS INC CL A 518439104 36,427 121,453 SH   OTR 2 121,453 0 0
LAZARD LTD SHS A G54050102 49,739 1,086,005 SH   DFND 1 1,086,005 0 0
LAZARD LTD SHS A G54050102 4,061 88,672 SH   OTR 2 88,672 0 0
LENDINGCLUB CORP COM NEW 52603A208 805 28,513 SH   DFND 1 28,513 0 0
LENNAR CORP CL A 526057104 48,163 514,121 SH   DFND 1 511,830 0 2,291
LGI HOMES INC COM 50187T106 902 6,358 SH   DFND 1 6,358 0 0
LILLY ELI & CO COM 532457108 2,240,036 9,695,031 SH   DFND 1 9,324,752 0 370,279
LILLY ELI & CO COM 532457108 39,160 169,485 SH   OTR 2 169,485 0 0
LINCOLN ELEC HLDGS INC COM 533900106 12,861 99,860 SH   DFND 1 99,860 0 0
LINDE PLC SHS G5494J103 248,397 846,673 SH   DFND 1 846,645 0 28
LITTELFUSE INC COM 537008104 88,252 322,946 SH   DFND 1 322,578 0 368
LITTELFUSE INC COM 537008104 7,738 28,318 SH   OTR 2 28,318 0 0
LIVEVOX HOLDING INC COM CL A 53838L100 6,685 1,025,313 SH   DFND 1 1,025,313 0 0
LOWES COS INC COM 548661107 103,008 507,778 SH   DFND 1 507,778 0 0
LULULEMON ATHLETICA INC COM 550021109 1,743,898 4,309,115 SH   DFND 1 4,089,757 0 219,358
LULULEMON ATHLETICA INC COM 550021109 33,425 82,591 SH   OTR 2 82,591 0 0
LYONDELLBASELL INDUSTRIES N SHS - A - N53745100 1,440 15,342 SH   DFND 1 15,342 0 0
M/I HOMES INC COM 55305B101 938 16,221 SH   DFND 1 16,221 0 0
MACOM TECH SOLUTIONS HLDGS I COM 55405Y100 52,426 808,157 SH   DFND 1 808,157 0 0
MACOM TECH SOLUTIONS HLDGS I COM 55405Y100 9,277 143,016 SH   OTR 2 143,016 0 0
MACYS INC COM 55616P104 1,546 68,389 SH   DFND 1 68,389 0 0
MAG SILVER CORP COM 55903Q104 7,305 451,556 SH   DFND 1 451,146 0 410
MAGELLAN MIDSTREAM PRTNRS LP COM UNIT RP LP 559080106 15,307 335,820 SH   DFND 1 335,820 0 0
MAKEMYTRIP LIMITED MAURITIUS SHS V5633W109 27,629 1,016,143 SH   DFND 1 1,016,143 0 0
MARINEMAX INC COM 567908108 915 18,856 SH   DFND 1 18,856 0 0
MARQETA INC CLASS A COM 57142B104 7,867 355,630 SH   DFND 1 354,299 0 1,331
MARRIOTT INTL INC NEW CL A 571903202 396,855 2,679,826 SH   DFND 1 2,586,452 0 93,374
MARRIOTT INTL INC NEW CL A 571903202 4,931 33,294 SH   OTR 2 33,294 0 0
MARSH & MCLENNAN COS INC COM 571748102 118,191 780,502 SH   DFND 1 780,502 0 0
MARVELL TECHNOLOGY INC COM 573874104 61,377 1,017,696 SH   DFND 1 1,012,266 0 5,430
MASTERCARD INCORPORATED CL A 57636Q104 1,983,360 5,704,556 SH   DFND 1 5,449,178 0 255,378
MASTERCARD INCORPORATED CL A 57636Q104 37,548 107,996 SH   OTR 2 107,996 0 0
MATCH GROUP INC NEW COM 57667L107 2,149,180 13,689,912 SH   DFND 1 12,928,939 0 760,973
MATCH GROUP INC NEW COM 57667L107 56,893 362,402 SH   OTR 2 362,402 0 0
MATSON INC COM 57686G105 2,111 26,150 SH   DFND 1 26,150 0 0
MAXIMUS INC COM 577933104 1,029 12,373 SH   DFND 1 12,373 0 0
MAXLINEAR INC COM 57776J100 29,709 603,223 SH   DFND 1 603,223 0 0
MAXLINEAR INC COM 57776J100 7,745 157,261 SH   OTR 2 157,261 0 0
MAYVILLE ENGR CO INC COM 578605107 12,450 662,239 SH   DFND 1 662,239 0 0
MAYVILLE ENGR CO INC COM 578605107 3,542 188,417 SH   OTR 2 188,417 0 0
MCDONALDS CORP COM 580135101 114,832 476,266 SH   DFND 1 470,232 0 6,034
MEDNAX INC COM 58502B106 941 33,111 SH   DFND 1 33,111 0 0
MEDTRONIC PLC SHS G5960L103 48,587 387,612 SH   DFND 1 387,612 0 0
MERCADOLIBRE INC COM 58733R102 3,054,661 1,818,900 SH   DFND 1 1,740,715 0 78,185
MERCADOLIBRE INC COM 58733R102 92,303 54,962 SH   OTR 2 54,962 0 0
METHODE ELECTRS INC COM 591520200 2,328 55,362 SH   DFND 1 55,362 0 0
METLIFE INC COM 59156R108 194,038 3,143,339 SH   DFND 1 3,143,339 0 0
METROPOLITAN BK HLDG CORP COM 591774104 17,314 205,381 SH   DFND 1 205,381 0 0
METROPOLITAN BK HLDG CORP COM 591774104 2,425 28,766 SH   OTR 2 28,766 0 0
METTLER TOLEDO INTERNATIONAL COM 592688105 2,935 2,131 SH   DFND 1 2,131 0 0
MGM RESORTS INTERNATIONAL COM 552953101 17,397 403,182 SH   DFND 1 403,182 0 0
MICRON TECHNOLOGY INC COM 595112103 2,698 38,005 SH   DFND 1 38,005 0 0
MICROSOFT CORP COM 594918104 5,571,569 19,762,944 SH   DFND 1 18,970,123 0 792,821
MICROSOFT CORP COM 594918104 101,099 358,609 SH   OTR 2 358,609 0 0
MILLER HERMAN INC COM 600544100 1,553 41,250 SH   DFND 1 41,250 0 0
MIRATI THERAPEUTICS INC COM 60468T105 46,407 262,321 SH   DFND 1 262,321 0 0
MODERNA INC COM 60770K107 899 2,337 SH   DFND 1 2,337 0 0
MOELIS & CO CL A 60786M105 13,409 216,729 SH   DFND 1 216,729 0 0
MOELIS & CO CL A 60786M105 2,976 48,106 SH   OTR 2 48,106 0 0
MOLINA HEALTHCARE INC COM 60855R100 91,105 335,796 SH   DFND 1 334,872 0 924
MONDELEZ INTL INC CL A 609207105 101,994 1,753,073 SH   DFND 1 1,753,073 0 0
MONOLITHIC PWR SYS INC COM 609839105 33,783 69,702 SH   DFND 1 69,274 0 428
MONTE ROSA THERAPEUTICS INC COM 61225M102 6,603 296,379 SH   DFND 1 296,379 0 0
MOODYS CORP COM 615369105 18,063 50,866 SH   DFND 1 26,303 0 24,563
MORNINGSTAR INC COM 617700109 5,294 20,436 SH   DFND 1 20,436 0 0
MPLX LP COM UNIT REP LTD 55336V100 27,660 971,558 SH   DFND 1 971,558 0 0
MUELLER WTR PRODS INC COM SER A 624758108 9,317 612,138 SH   DFND 1 612,138 0 0
MUELLER WTR PRODS INC COM SER A 624758108 1,944 127,742 SH   OTR 2 127,742 0 0
MURPHY OIL CORP COM 626717102 1,024 40,993 SH   DFND 1 40,993 0 0
NATERA INC COM 632307104 71,265 639,492 SH   DFND 1 639,492 0 0
NATIONAL ENERGY SERVICES REU SHS G6375R107 12,830 1,024,784 SH   DFND 1 1,023,880 0 904
NATIONAL STORAGE AFFILIATES COM SHS BEN IN 637870106 32,066 607,434 SH   DFND 1 607,434 0 0
NATIONAL STORAGE AFFILIATES COM SHS BEN IN 637870106 7,727 146,366 SH   OTR 2 146,366 0 0
NATIONAL VISION HLDGS INC COM 63845R107 33,430 588,873 SH   DFND 1 588,873 0 0
NATIONAL VISION HLDGS INC COM 63845R107 8,564 150,854 SH   OTR 2 150,854 0 0
NEOGENOMICS INC COM NEW 64049M209 11,582 240,087 SH   DFND 1 240,087 0 0
NEOGENOMICS INC COM NEW 64049M209 2,949 61,139 SH   OTR 2 61,139 0 0
NETFLIX INC COM 64110L106 3,731,466 6,113,750 SH   DFND 1 5,773,667 0 340,083
NETFLIX INC COM 64110L106 87,896 144,012 SH   OTR 2 144,012 0 0
NEVRO CORP COM 64157F103 40,630 349,118 SH   DFND 1 349,118 0 0
NEVRO CORP COM 64157F103 3,466 29,783 SH   OTR 2 29,783 0 0
NEW FORTRESS ENERGY INC COM CL A 644393100 4,232 152,494 SH   DFND 1 152,426 0 68
NEW JERSEY RES CORP COM 646025106 1,628 46,755 SH   DFND 1 46,755 0 0
NEWMONT CORP COM 651639106 14,556 268,068 SH   DFND 1 267,844 0 224
NEXSTAR MEDIA GROUP INC CL A 65336K103 902 5,938 SH   DFND 1 5,938 0 0
NEXTERA ENERGY INC COM 65339F101 317,069 4,038,068 SH   DFND 1 3,939,005 0 99,063
NEXTERA ENERGY INC UNIT 99/99/9999 65339F739 6,028 117,943 SH   DFND 1 77,390 0 40,553
NEXTERA ENERGY PARTNERS LP COM UNIT PART IN 65341B106 198,865 2,638,864 SH   DFND 1 2,610,942 0 27,922
NEXTERA ENERGY PARTNERS LP COM UNIT PART IN 65341B106 9,529 126,443 SH   OTR 2 126,443 0 0
NIKE INC CL B 654106103 1,890,164 13,014,975 SH   DFND 1 12,197,644 0 817,331
NIKE INC CL B 654106103 50,517 347,838 SH   OTR 2 347,838 0 0
NISOURCE INC COM 65473P105 35,258 1,455,124 SH   DFND 1 1,361,590 0 93,534
NLIGHT INC COM 65487K100 31,946 1,133,239 SH   DFND 1 1,133,239 0 0
NLIGHT INC COM 65487K100 5,575 197,762 SH   OTR 2 197,762 0 0
NORDSON CORP COM 655663102 63,572 266,941 SH   DFND 1 265,933 0 1,008
NORFOLK SOUTHN CORP COM 655844108 14,678 61,349 SH   DFND 1 38,817 0 22,532
NORTONLIFELOCK INC COM 668771108 2,623 103,664 SH   DFND 1 103,664 0 0
NOVA LTD COM M7516K103 1,189 11,623 SH   DFND 1 11,623 0 0
NOVAVAX INC COM NEW 670002401 29,720 143,362 SH   DFND 1 143,362 0 0
NOVO-NORDISK A S ADR 670100205 46,870 488,181 SH   DFND 1 488,181 0 0
NURIX THERAPEUTICS INC COM 67080M103 25,416 848,316 SH   DFND 1 848,316 0 0
NURIX THERAPEUTICS INC COM 67080M103 2,124 70,903 SH   OTR 2 70,903 0 0
NUSTAR ENERGY LP UNIT COM 67058H102 4,933 313,386 SH   DFND 1 313,386 0 0
NUTRIEN LTD COM 67077M108 10,792 166,460 SH   DFND 1 166,310 0 150
NUVASIVE INC COM 670704105 20,004 334,232 SH   DFND 1 334,232 0 0
NVIDIA CORPORATION COM 67066G104 5,983,609 28,884,001 SH   DFND 1 27,336,612 0 1,547,389
NVIDIA CORPORATION COM 67066G104 163,330 788,422 SH   OTR 2 788,422 0 0
O-I GLASS INC COM 67098H104 886 62,098 SH   DFND 1 62,098 0 0
OCEANEERING INTL INC COM 675232102 1,688 126,721 SH   DFND 1 126,721 0 0
OGE ENERGY CORP COM 670837103 32,384 982,521 SH   DFND 1 982,521 0 0
OKTA INC CL A 679295105 991,017 4,175,517 SH   DFND 1 3,996,229 0 179,288
OKTA INC CL A 679295105 25,844 108,891 SH   OTR 2 108,891 0 0
OLD DOMINION FREIGHT LINE IN COM 679580100 829 2,900 SH   DFND 1 2,900 0 0
OLINK HLDG AB SPONSORED ADS 680710100 3,739 154,183 SH   DFND 1 154,183 0 0
OMNICELL COM COM 68213N109 910 6,130 SH   DFND 1 6,130 0 0
ON HLDG AG NAMEN AKT A H5919C104 13,844 459,498 SH   DFND 1 459,498 0 0
ON HLDG AG NAMEN AKT A H5919C104 1,337 44,360 SH   OTR 2 44,360 0 0
ON SEMICONDUCTOR CORP COM 682189105 66,941 1,462,546 SH   DFND 1 1,456,520 0 6,026
ONEOK INC NEW COM 682680103 28,386 489,504 SH   DFND 1 489,504 0 0
OPEN LENDING CORP COM CL A 68373J104 32,349 896,833 SH   DFND 1 896,833 0 0
OPEN LENDING CORP COM CL A 68373J104 4,148 114,996 SH   OTR 2 114,996 0 0
ORACLE CORP COM 68389X105 4,703 53,978 SH   DFND 1 53,978 0 0
OREILLY AUTOMOTIVE INC COM 67103H107 50,567 82,753 SH   DFND 1 82,329 0 424
ORIC PHARMACEUTICALS INC COM 68622P109 18,916 904,668 SH   DFND 1 904,668 0 0
ORIC PHARMACEUTICALS INC COM 68622P109 1,991 95,208 SH   OTR 2 95,208 0 0
ORTHO CLINICAL DIAGNOSTICS H ORD SHS G6829J107 16,310 882,568 SH   DFND 1 882,568 0 0
OSHKOSH CORP COM 688239201 25,785 251,877 SH   DFND 1 251,877 0 0
OTIS WORLDWIDE CORP COM 68902V107 113,112 1,374,724 SH   DFND 1 1,374,724 0 0
OUTSET MED INC COM 690145107 44,897 908,113 SH   DFND 1 908,113 0 0
OUTSET MED INC COM 690145107 5,095 103,051 SH   OTR 2 103,051 0 0
OWENS & MINOR INC NEW COM 690732102 985 31,484 SH   DFND 1 31,484 0 0
PACWEST BANCORP DEL COM 695263103 43,181 952,790 SH   DFND 1 952,790 0 0
PACWEST BANCORP DEL COM 695263103 6,026 132,969 SH   OTR 2 132,969 0 0
PAGERDUTY INC COM 69553P100 13,322 321,627 SH   DFND 1 321,627 0 0
PAGERDUTY INC COM 69553P100 3,385 81,719 SH   OTR 2 81,719 0 0
PALO ALTO NETWORKS INC COM 697435105 70,276 146,713 SH   DFND 1 146,019 0 694
PATRICK INDS INC COM 703343103 1,422 17,067 SH   DFND 1 17,067 0 0
PAYCOM SOFTWARE INC COM 70432V102 45,455 91,689 SH   DFND 1 91,178 0 511
PAYONEER GLOBAL INC COM 70451X104 23,793 2,782,819 SH   DFND 1 2,782,819 0 0
PAYONEER GLOBAL INC COM 70451X104 3,279 383,524 SH   OTR 2 383,524 0 0
PAYPAL HLDGS INC COM 70450Y103 2,308,434 8,871,426 SH   DFND 1 8,436,924 0 434,502
PAYPAL HLDGS INC COM 70450Y103 45,596 175,229 SH   OTR 2 175,229 0 0
PDC ENERGY INC COM 69327R101 117,116 2,471,329 SH   DFND 1 2,470,710 0 619
PDC ENERGY INC COM 69327R101 12,506 263,889 SH   OTR 2 263,889 0 0
PELOTON INTERACTIVE INC CL A COM 70614W100 224 2,576 SH   DFND 1 2,573 0 3
PEMBINA PIPELINE CORP COM 706327103 26,867 848,004 SH   DFND 1 848,004 0 0
PENN NATL GAMING INC COM 707569109 19,701 271,886 SH   DFND 1 271,886 0 0
PEPSICO INC COM 713448108 118,517 787,958 SH   DFND 1 776,237 0 11,721
PERFORMANCE FOOD GROUP CO COM 71377A103 126,646 2,725,916 SH   DFND 1 2,720,748 0 5,168
PERFORMANCE FOOD GROUP CO COM 71377A103 11,334 243,953 SH   OTR 2 243,953 0 0
PG&E CORP COM 69331C108 32,337 3,368,440 SH   DFND 1 3,368,440 0 0
PHILIP MORRIS INTL INC COM 718172109 15,433 162,812 SH   DFND 1 162,812 0 0
PHILLIPS 66 PARTNERS LP COM UNIT REP INT 718549207 11,211 312,714 SH   DFND 1 312,714 0 0
PHREESIA INC COM 71944F106 73,620 1,193,204 SH   DFND 1 1,193,204 0 0
PHREESIA INC COM 71944F106 7,213 116,897 SH   OTR 2 116,897 0 0
PINNACLE FINL PARTNERS INC COM 72346Q104 61,309 651,671 SH   DFND 1 651,671 0 0
PINNACLE FINL PARTNERS INC COM 72346Q104 6,441 68,461 SH   OTR 2 68,461 0 0
PINTEREST INC CL A 72352L106 29,940 587,633 SH   DFND 1 584,037 0 3,596
PIONEER NAT RES CO COM 723787107 24,407 146,578 SH   DFND 1 146,450 0 128
PLAINS ALL AMERN PIPELINE L UNIT LTD PARTN 726503105 4,165 409,561 SH   DFND 1 409,561 0 0
PLAINS GP HLDGS L P LTD PARTNR INT A 72651A207 17,765 1,648,742 SH   DFND 1 1,648,742 0 0
PLYMOUTH INDL REIT INC COM 729640102 18,208 800,325 SH   DFND 1 800,325 0 0
PLYMOUTH INDL REIT INC COM 729640102 2,670 117,381 SH   OTR 2 117,381 0 0
PMV PHARMACEUTICALS INC COM 69353Y103 10,551 354,049 SH   DFND 1 354,049 0 0
PNC FINL SVCS GROUP INC COM 693475105 240,007 1,226,779 SH   DFND 1 1,226,779 0 0
POLARIS INC COM 731068102 1,998 16,696 SH   DFND 1 16,696 0 0
POOL CORP COM 73278L105 833 1,917 SH   DFND 1 1,917 0 0
POTLATCHDELTIC CORPORATION COM 737630103 2,063 39,992 SH   DFND 1 39,992 0 0
PRAXIS PRECISION MEDICINES I COM 74006W108 3,613 195,422 SH   DFND 1 195,422 0 0
PRESTIGE CONSMR HEALTHCARE I COM 74112D101 20,145 359,016 SH   DFND 1 359,016 0 0
PRESTIGE CONSMR HEALTHCARE I COM 74112D101 4,675 83,322 SH   OTR 2 83,322 0 0
PRICE T ROWE GROUP INC COM 74144T108 829 4,214 SH   DFND 1 4,214 0 0
PRIMORIS SVCS CORP COM 74164F103 2,173 88,716 SH   DFND 1 88,716 0 0
PROCTER AND GAMBLE CO COM 742718109 81,745 584,727 SH   DFND 1 564,140 0 20,587
PROGYNY INC COM 74340E103 84,156 1,502,774 SH   DFND 1 1,498,416 0 4,358
PROGYNY INC COM 74340E103 7,166 127,968 SH   OTR 2 127,968 0 0
PROLOGIS INC. COM 74340W103 31,453 250,758 SH   DFND 1 250,758 0 0
PROQR THRAPEUTICS N V SHS EURO N71542109 15,414 1,841,578 SH   DFND 1 1,841,578 0 0
PROTHENA CORP PLC SHS G72800108 1,017 14,271 SH   DFND 1 14,271 0 0
PROVIDENT FINL SVCS INC COM 74386T105 1,324 56,432 SH   DFND 1 56,432 0 0
PTC INC COM 69370C100 843 7,034 SH   DFND 1 7,034 0 0
PUBLIC SVC ENTERPRISE GRP IN COM 744573106 151,161 2,482,113 SH   DFND 1 2,406,353 0 75,760
Q2 HLDGS INC COM 74736L109 14,632 182,580 SH   DFND 1 182,580 0 0
Q2 HLDGS INC COM 74736L109 4,327 53,997 SH   OTR 2 53,997 0 0
QIAGEN NV SHS NEW N72482123 29,242 565,833 SH   DFND 1 565,833 0 0
QUALCOMM INC COM 747525103 153,639 1,191,185 SH   DFND 1 1,181,321 0 9,864
QUANTA SVCS INC COM 74762E102 94,317 828,649 SH   DFND 1 825,224 0 3,425
RALPH LAUREN CORP CL A 751212101 30,463 274,344 SH   DFND 1 274,344 0 0
RAPID MICRO BIOSYSTEMS INC CLASS A COM 75340L104 2,283 123,605 SH   DFND 1 123,605 0 0
RAYTHEON TECHNOLOGIES CORP COM 75513E101 110,027 1,279,974 SH   DFND 1 1,279,974 0 0
REGENERON PHARMACEUTICALS COM 75886F107 1,092 1,805 SH   DFND 1 1,805 0 0
RENAISSANCERE HLDGS LTD COM G7496G103 48,685 349,250 SH   DFND 1 349,250 0 0
REPLIGEN CORP COM 759916109 24,732 85,582 SH   DFND 1 85,582 0 0
RETAIL OPPORTUNITY INVTS COR COM 76131N101 25,866 1,484,856 SH   DFND 1 1,484,856 0 0
RETAIL OPPORTUNITY INVTS COR COM 76131N101 3,422 196,430 SH   OTR 2 196,430 0 0
REVANCE THERAPEUTICS INC COM 761330109 53,751 1,929,315 SH   DFND 1 1,929,315 0 0
REVANCE THERAPEUTICS INC COM 761330109 4,352 156,211 SH   OTR 2 156,211 0 0
REXNORD CORP COM 76169B102 58,529 910,377 SH   DFND 1 910,377 0 0
REXNORD CORP COM 76169B102 8,112 126,186 SH   OTR 2 126,186 0 0
RINGCENTRAL INC CL A 76680R206 30,271 139,177 SH   DFND 1 138,355 0 822
ROBERT HALF INTL INC COM 770323103 1,812 18,057 SH   DFND 1 18,057 0 0
ROBLOX CORP CL A 771049103 480,686 6,362,486 SH   DFND 1 6,051,617 0 310,869
ROBLOX CORP CL A 771049103 11,852 156,882 SH   OTR 2 156,882 0 0
ROKU INC COM CL A 77543R102 36,170 115,431 SH   DFND 1 114,902 0 529
ROSS STORES INC COM 778296103 117,802 1,082,241 SH   DFND 1 1,082,241 0 0
ROYAL CARIBBEAN GROUP COM V7780T103 99,248 1,115,770 SH   DFND 1 1,115,770 0 0
ROYAL DUTCH SHELL PLC SPONS ADR A 780259206 20,373 457,108 SH   DFND 1 456,715 0 393
ROYAL GOLD INC COM 780287108 12,386 129,711 SH   DFND 1 129,711 0 0
RUSH ENTERPRISES INC CL A 781846209 26,937 596,482 SH   DFND 1 596,482 0 0
RUSH ENTERPRISES INC CL A 781846209 4,051 89,695 SH   OTR 2 89,695 0 0
RUSH STREET INTERACTIVE INC COM 782011100 26,949 1,402,827 SH   DFND 1 1,402,827 0 0
RUSH STREET INTERACTIVE INC COM 782011100 3,669 191,016 SH   OTR 2 191,016 0 0
RYAN SPECIALTY GROUP HLDGS I CL A 78351F107 24,776 731,509 SH   DFND 1 731,509 0 0
S&P GLOBAL INC COM 78409V104 730,846 1,720,083 SH   DFND 1 1,582,050 0 138,033
S&P GLOBAL INC COM 78409V104 23,090 54,344 SH   OTR 2 54,344 0 0
SAIA INC COM 78709Y105 80,952 340,094 SH   DFND 1 340,094 0 0
SAIA INC COM 78709Y105 11,414 47,950 SH   OTR 2 47,950 0 0
SALESFORCE COM INC COM 79466L302 2,568,635 9,470,669 SH   DFND 1 8,843,629 0 627,040
SALESFORCE COM INC COM 79466L302 65,522 241,582 SH   OTR 2 241,582 0 0
SANMINA CORPORATION COM 801056102 1,815 47,088 SH   DFND 1 47,088 0 0
SAREPTA THERAPEUTICS INC COM 803607100 5,037 54,461 SH   DFND 1 54,461 0 0
SBA COMMUNICATIONS CORP NEW CL A 78410G104 51,994 157,285 SH   DFND 1 143,773 0 13,512
SCHLUMBERGER LTD COM STK 806857108 10,204 344,278 SH   DFND 1 344,000 0 278
SCRIPPS E W CO OHIO CL A NEW 811054402 1,091 60,386 SH   DFND 1 60,386 0 0
SEA LTD SPONSORD ADS 81141R100 2,142,868 6,723,146 SH   DFND 1 6,247,794 0 475,352
SEA LTD SPONSORD ADS 81141R100 98,113 307,825 SH   OTR 2 307,825 0 0
SEAGEN INC COM 81181C104 55,587 327,370 SH   DFND 1 326,990 0 380
SELECT MED HLDGS CORP COM 81619Q105 2,229 61,619 SH   DFND 1 61,619 0 0
SELECT SECTOR SPDR TR ENERGY 81369Y506 754 14,483 SH   DFND 1 14,326 0 157
SEMPRA COM 816851109 40,028 316,423 SH   DFND 1 316,423 0 0
SERVICE CORP INTL COM 817565104 12,993 215,617 SH   DFND 1 215,617 0 0
SHIFT4 PMTS INC CL A 82452J109 56,827 733,068 SH   DFND 1 730,184 0 2,884
SHOALS TECHNOLOGIES GROUP IN CL A 82489W107 4,545 163,030 SH   DFND 1 162,897 0 133
SHOCKWAVE MED INC COM 82489T104 59,996 291,414 SH   DFND 1 291,414 0 0
SHOPIFY INC CL A 82509L107 6,123,215 4,516,378 SH   DFND 1 4,322,591 0 193,787
SHOPIFY INC CL A 82509L107 156,515 115,443 SH   OTR 2 115,443 0 0
SHUTTERSTOCK INC COM 825690100 1,035 9,135 SH   DFND 1 9,135 0 0
SIBANYE STILLWATER LTD SPONSORED ADR 82575P107 2,964 240,183 SH   DFND 1 239,983 0 200
SIGHT SCIENCES INC COM 82657M105 879 38,733 SH   DFND 1 38,733 0 0
SILK RD MED INC COM 82710M100 27,098 492,429 SH   DFND 1 492,429 0 0
SILK RD MED INC COM 82710M100 4,591 83,419 SH   OTR 2 83,419 0 0
SILVERGATE CAP CORP CL A 82837P408 25,402 219,933 SH   DFND 1 219,933 0 0
SILVERGATE CAP CORP CL A 82837P408 3,517 30,446 SH   OTR 2 30,446 0 0
SITE CTRS CORP COM 82981J109 2,120 137,299 SH   DFND 1 137,299 0 0
SITEONE LANDSCAPE SUPPLY INC COM 82982L103 1,568 7,860 SH   DFND 1 7,860 0 0
SIX FLAGS ENTMT CORP NEW COM 83001A102 453 10,658 SH   DFND 1 10,658 0 0
SLM CORP COM 78442P106 75,588 4,294,794 SH   DFND 1 4,294,794 0 0
SMARTSHEET INC COM CL A 83200N103 57,873 840,929 SH   DFND 1 839,130 0 1,799
SNAP INC CL A 83304A106 3,224,574 43,652,009 SH   DFND 1 41,033,253 0 2,618,756
SNAP INC CL A 83304A106 102,384 1,385,999 SH   OTR 2 1,385,999 0 0
SNOWFLAKE INC CL A 833445109 753,067 2,490,053 SH   DFND 1 2,341,325 0 148,728
SNOWFLAKE INC CL A 833445109 19,376 64,068 SH   OTR 2 64,068 0 0
SOPHIA GENETICS SA ORDINARY SHARES H82027105 9,915 565,620 SH   DFND 1 565,620 0 0
SOPHIA GENETICS SA ORDINARY SHARES H82027105 1,399 79,797 SH   OTR 2 79,797 0 0
SOUTHERN CO COM 842587107 33,643 542,886 SH   DFND 1 542,886 0 0
SOUTHERN COPPER CORP COM 84265V105 5,059 90,122 SH   DFND 1 90,044 0 78
SOUTHSTATE CORPORATION COM 840441109 1,765 23,632 SH   DFND 1 23,632 0 0
SOUTHWEST AIRLS CO COM 844741108 1,163 22,617 SH   DFND 1 22,617 0 0
SPDR S&P MIDCAP 400 ETF TR UTSER1 S&PDCRP 78467Y107 2,068 4,300 SH   DFND 1 4,300 0 0
SPDR SER TR S&P METALS MNG 78464A755 5,295 126,867 SH   DFND 1 125,487 0 1,380
SPIRIT AEROSYSTEMS HLDGS INC COM CL A 848574109 7,012 158,676 SH   DFND 1 158,676 0 0
SPIRIT AEROSYSTEMS HLDGS INC COM CL A 848574109 2,056 46,534 SH   OTR 2 46,534 0 0
SPOTIFY TECHNOLOGY S A SHS L8681T102 423,256 1,878,301 SH   DFND 1 1,785,689 0 92,612
SPOTIFY TECHNOLOGY S A SHS L8681T102 8,246 36,594 SH   OTR 2 36,594 0 0
SPRINGWORKS THERAPEUTICS INC COM 85205L107 39,640 624,833 SH   DFND 1 624,833 0 0
SPRINGWORKS THERAPEUTICS INC COM 85205L107 1,312 20,688 SH   OTR 2 20,688 0 0
SPROUT SOCIAL INC COM CL A 85209W109 19,275 158,049 SH   DFND 1 158,049 0 0
SPROUT SOCIAL INC COM CL A 85209W109 4,525 37,109 SH   OTR 2 37,109 0 0
SPROUTS FMRS MKT INC COM 85208M102 1,827 78,852 SH   DFND 1 78,852 0 0
SQUARE INC CL A 852234103 3,163,009 13,187,997 SH   DFND 1 12,474,152 0 713,845
SQUARE INC CL A 852234103 97,360 405,938 SH   OTR 2 405,938 0 0
STAAR SURGICAL CO COM PAR $0.01 852312305 1,293 10,061 SH   DFND 1 10,061 0 0
STARBUCKS CORP COM 855244109 840 7,619 SH   DFND 1 7,619 0 0
STARWOOD PPTY TR INC COM 85571B105 16,055 657,725 SH   DFND 1 657,725 0 0
STEEL DYNAMICS INC COM 858119100 21,443 366,676 SH   DFND 1 366,480 0 196
STERLING CHECK CORP COM 85917T109 7,363 283,623 SH   DFND 1 283,623 0 0
STERLING CHECK CORP COM 85917T109 1,118 43,062 SH   OTR 2 43,062 0 0
STRYKER CORPORATION COM 863667101 38,551 146,180 SH   DFND 1 146,180 0 0
SUMMIT HOTEL PPTYS INC COM 866082100 33,388 3,467,069 SH   DFND 1 3,467,069 0 0
SUMMIT HOTEL PPTYS INC COM 866082100 4,928 511,720 SH   OTR 2 511,720 0 0
SUMMIT MATLS INC CL A 86614U100 60,660 1,897,415 SH   DFND 1 1,897,415 0 0
SUMMIT MATLS INC CL A 86614U100 8,713 272,529 SH   OTR 2 272,529 0 0
SUN CTRY AIRLS HLDGS INC COM 866683105 26,325 784,895 SH   DFND 1 784,895 0 0
SUN CTRY AIRLS HLDGS INC COM 866683105 3,994 119,070 SH   OTR 2 119,070 0 0
SUNCOR ENERGY INC NEW COM 867224107 9,239 445,481 SH   DFND 1 445,032 0 449
SUNNOVA ENERGY INTL INC. COM 86745K104 12,019 364,871 SH   DFND 1 364,555 0 316
SUNPOWER CORP COM 867652406 1,212 53,435 SH   DFND 1 53,435 0 0
SUNRUN INC COM 86771W105 8,657 196,758 SH   DFND 1 196,626 0 132
SYNEOS HEALTH INC CL A 87166B102 4,580 52,350 SH   DFND 1 52,350 0 0
SYSCO CORP COM 871829107 14,453 184,116 SH   DFND 1 184,116 0 0
TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADS 874039100 1,324,978 11,867,241 SH   DFND 1 11,747,931 0 119,310
TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADS 874039100 23,446 209,997 SH   OTR 2 209,997 0 0
TALKSPACE INC COM 87427V103 7,676 2,102,985 SH   DFND 1 2,102,985 0 0
TALKSPACE INC COM 87427V103 1,001 274,328 SH   OTR 2 274,328 0 0
TANDEM DIABETES CARE INC COM NEW 875372203 59,324 496,937 SH   DFND 1 496,937 0 0
TANDEM DIABETES CARE INC COM NEW 875372203 7,634 63,946 SH   OTR 2 63,946 0 0
TARGA RES CORP COM 87612G101 166,591 3,385,310 SH   DFND 1 3,270,009 0 115,301
TARGET CORP COM 87612E106 1,008,503 4,408,372 SH   DFND 1 4,262,702 0 145,670
TARGET CORP COM 87612E106 20,151 88,084 SH   OTR 2 88,084 0 0
TC ENERGY CORP COM 87807B107 6,490 134,993 SH   DFND 1 134,332 0 661
TEGNA INC COM 87901J105 621 31,513 SH   DFND 1 31,513 0 0
TELADOC HEALTH INC COM 87918A105 120,433 949,710 SH   DFND 1 737,136 0 212,574
TELADOC HEALTH INC COM 87918A105 7,514 59,257 SH   OTR 2 59,257 0 0
TELEDYNE TECHNOLOGIES INC COM 879360105 35,217 81,980 SH   DFND 1 81,581 0 399
TELUS INTL CDA INC SUB VTG SHS 87975H100 16,542 472,501 SH   DFND 1 472,501 0 0
TERADATA CORP DEL COM 88076W103 1,407 24,532 SH   DFND 1 24,532 0 0
TEREX CORP NEW COM 880779103 888 21,091 SH   DFND 1 21,091 0 0
TESLA INC COM 88160R101 8,024,612 10,347,929 SH   DFND 1 9,782,875 0 565,054
TESLA INC COM 88160R101 219,003 282,410 SH   OTR 2 282,410 0 0
TEXAS INSTRS INC COM 882508104 239,138 1,244,148 SH   DFND 1 1,244,148 0 0
TEXAS ROADHOUSE INC COM 882681109 33,719 369,200 SH   DFND 1 366,896 0 2,304
TFI INTL INC COM 87241L109 29,799 291,634 SH   DFND 1 291,634 0 0
THE BEAUTY HEALTH COMPANY COM CL A 88331L108 2,123 81,749 SH   DFND 1 81,749 0 0
THE TRADE DESK INC COM CL A 88339J105 922,323 13,119,817 SH   DFND 1 12,436,458 0 683,359
THE TRADE DESK INC COM CL A 88339J105 20,657 293,839 SH   OTR 2 293,839 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102 146,863 257,054 SH   DFND 1 257,054 0 0
TJX COS INC NEW COM 872540109 982,363 14,888,806 SH   DFND 1 14,045,011 0 843,795
TJX COS INC NEW COM 872540109 19,460 294,931 SH   OTR 2 294,931 0 0
TOAST INC CL A 888787108 12,488 250,000 SH   DFND 1 250,000 0 0
TOLL BROTHERS INC COM 889478103 27,628 499,691 SH   DFND 1 499,691 0 0
TOTALENERGIES SE SPONSORED ADS 89151E109 44,827 935,267 SH   DFND 1 934,962 0 305
TOWER SEMICONDUCTOR LTD SHS NEW M87915274 46,869 1,567,555 SH   DFND 1 1,567,555 0 0
TOWER SEMICONDUCTOR LTD SHS NEW M87915274 6,778 226,675 SH   OTR 2 226,675 0 0
TRANE TECHNOLOGIES PLC SHS G8994E103 55,219 319,831 SH   DFND 1 318,499 0 1,332
TRINITY INDS INC COM 896522109 27,756 1,021,568 SH   DFND 1 1,021,568 0 0
TRINITY INDS INC COM 896522109 4,867 179,120 SH   OTR 2 179,120 0 0
TRITON INTL LTD CL A G9078F107 959 18,431 SH   DFND 1 18,431 0 0
TRONOX HOLDINGS PLC SHS G9087Q102 403 16,334 SH   DFND 1 16,334 0 0
TRUIST FINL CORP COM 89832Q109 217,750 3,712,710 SH   DFND 1 3,712,710 0 0
TURNING POINT THERAPEUTICS I COM 90041T108 28,731 432,491 SH   DFND 1 432,491 0 0
TURNING POINT THERAPEUTICS I COM 90041T108 1,550 23,339 SH   OTR 2 23,339 0 0
TWILIO INC CL A 90138F102 1,938,383 6,075,485 SH   DFND 1 5,741,842 0 333,643
TWILIO INC CL A 90138F102 48,845 153,094 SH   OTR 2 153,094 0 0
TYRA BIOSCIENCES INC COM 90240B106 8,245 468,750 SH   DFND 1 468,750 0 0
UBER TECHNOLOGIES INC COM 90353T100 1,761,679 39,323,182 SH   DFND 1 37,389,239 0 1,933,943
UBER TECHNOLOGIES INC COM 90353T100 34,286 765,319 SH   OTR 2 765,319 0 0
UFP INDUSTRIES INC COM 90278Q108 1,745 25,664 SH   DFND 1 25,664 0 0
ULTA BEAUTY INC COM 90384S303 835 2,313 SH   DFND 1 2,313 0 0
UMB FINL CORP COM 902788108 1,821 18,830 SH   DFND 1 18,830 0 0
UMH PPTYS INC COM 903002103 13,326 581,917 SH   DFND 1 581,917 0 0
UMH PPTYS INC COM 903002103 3,898 170,204 SH   OTR 2 170,204 0 0
UNION PAC CORP COM 907818108 249,201 1,271,371 SH   DFND 1 1,075,188 0 196,183
UNION PAC CORP COM 907818108 7,892 40,261 SH   OTR 2 40,261 0 0
UNITED PARCEL SERVICE INC CL B 911312106 15,758 86,533 SH   DFND 1 86,533 0 0
UNITED RENTALS INC COM 911363109 79,808 227,420 SH   DFND 1 227,420 0 0
UNITEDHEALTH GROUP INC COM 91324P102 715,565 1,831,306 SH   DFND 1 1,787,321 0 43,985
UNITEDHEALTH GROUP INC COM 91324P102 10,278 26,305 SH   OTR 2 26,305 0 0
UNIVERSAL CORP VA COM 913456109 1,697 35,122 SH   DFND 1 35,122 0 0
UNIVERSAL DISPLAY CORP COM 91347P105 45,528 266,305 SH   DFND 1 265,526 0 779
URBAN EDGE PPTYS COM 91704F104 1,789 97,727 SH   DFND 1 97,727 0 0
URBAN OUTFITTERS INC COM 917047102 946 31,861 SH   DFND 1 31,861 0 0
UTZ BRANDS INC COM CL A 918090101 8,483 495,228 SH   DFND 1 495,228 0 0
UTZ BRANDS INC COM CL A 918090101 2,459 143,536 SH   OTR 2 143,536 0 0
VALE S A SPONSORED ADS 91912E105 3,836 275,012 SH   DFND 1 274,756 0 256
VALERO ENERGY CORP COM 91913Y100 10,796 152,977 SH   DFND 1 152,895 0 82
VALLEY NATL BANCORP COM 919794107 2,887 216,879 SH   DFND 1 216,879 0 0
VANGUARD INDEX FDS GROWTH ETF 922908736 598 2,061 SH   DFND 1 2,061 0 0
VARONIS SYS INC COM 922280102 51,959 853,900 SH   DFND 1 853,900 0 0
VARONIS SYS INC COM 922280102 9,431 154,982 SH   OTR 2 154,982 0 0
VERACYTE INC COM 92337F107 18,407 396,274 SH   DFND 1 396,274 0 0
VERACYTE INC COM 92337F107 3,367 72,486 SH   OTR 2 72,486 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 144,783 798,187 SH   DFND 1 667,894 0 130,293
VERTEX PHARMACEUTICALS INC COM 92532F100 5,654 31,172 SH   OTR 2 31,172 0 0
VERVE THERAPEUTICS INC COM 92539P101 17,182 365,577 SH   DFND 1 365,577 0 0
VIMEO INC COMMON STOCK 92719V100 16,808 572,275 SH   DFND 1 569,604 0 2,671
VISA INC COM CL A 92826C839 2,987,770 13,413,110 SH   DFND 1 12,814,468 0 598,642
VISA INC COM CL A 92826C839 60,698 272,493 SH   OTR 2 272,493 0 0
VISHAY INTERTECHNOLOGY INC COM 928298108 1,078 53,651 SH   DFND 1 53,651 0 0
VROOM INC COM 92918V109 15,392 697,418 SH   DFND 1 697,418 0 0
VROOM INC COM 92918V109 2,154 97,603 SH   OTR 2 97,603 0 0
VTEX SHS CL A G9470A102 18,533 900,969 SH   DFND 1 900,969 0 0
WABTEC COM 929740108 11,975 138,907 SH   DFND 1 138,907 0 0
WALMART INC COM 931142103 191,638 1,374,929 SH   DFND 1 1,362,808 0 12,121
WASTE CONNECTIONS INC COM 94106B101 3,339 26,515 SH   DFND 1 6,512 0 20,003
WESTERN MIDSTREAM PARTNERS L COM UNIT LP INT 958669103 27,522 1,313,054 SH   DFND 1 1,313,054 0 0
WESTLAKE CHEM CORP COM 960413102 3,731 40,934 SH   DFND 1 40,934 0 0
WEX INC COM 96208T104 50,056 284,183 SH   DFND 1 283,216 0 967
WHEATON PRECIOUS METALS CORP COM 962879102 4,715 125,457 SH   DFND 1 125,347 0 110
WILLIAMS COS INC COM 969457100 157,570 6,074,410 SH   DFND 1 5,914,946 0 159,464
WILLIAMS SONOMA INC COM 969904101 1,941 10,944 SH   DFND 1 10,944 0 0
WILLSCOT MOBIL MINI HLDNG CO COM CL A 971378104 91,768 2,893,083 SH   DFND 1 2,893,083 0 0
WILLSCOT MOBIL MINI HLDNG CO COM CL A 971378104 13,035 410,934 SH   OTR 2 410,934 0 0
WINGSTOP INC COM 974155103 24,953 152,220 SH   DFND 1 152,220 0 0
WINGSTOP INC COM 974155103 6,881 41,975 SH   OTR 2 41,975 0 0
WINTRUST FINL CORP COM 97650W108 51,009 634,681 SH   DFND 1 634,681 0 0
WINTRUST FINL CORP COM 97650W108 5,808 72,265 SH   OTR 2 72,265 0 0
WORKDAY INC CL A 98138H101 574,547 2,299,202 SH   DFND 1 2,069,673 0 229,529
WORKDAY INC CL A 98138H101 21,122 84,524 SH   OTR 2 84,524 0 0
WSFS FINL CORP COM 929328102 25,322 493,511 SH   DFND 1 493,511 0 0
WSFS FINL CORP COM 929328102 3,787 73,802 SH   OTR 2 73,802 0 0
XCEL ENERGY INC COM 98389B100 51,082 817,307 SH   DFND 1 817,307 0 0
YETI HLDGS INC COM 98585X104 24,871 290,246 SH   DFND 1 288,926 0 1,320
YUM BRANDS INC COM 988498101 2,597 21,235 SH   DFND 1 21,235 0 0
ZAI LAB LTD ADR 98887Q104 38,238 362,826 SH   DFND 1 362,826 0 0
ZEBRA TECHNOLOGIES CORPORATI CL A 989207105 826 1,602 SH   DFND 1 1,602 0 0
ZENDESK INC COM 98936J101 25,547 219,494 SH   DFND 1 218,288 0 1,206
ZIMMER BIOMET HOLDINGS INC COM 98956P102 164,367 1,123,034 SH   DFND 1 1,123,034 0 0
ZOETIS INC CL A 98978V103 9,008 46,397 SH   DFND 1 0 0 46,397
ZOOMINFO TECHNOLOGIES INC COM CL A 98980F104 191,631 3,131,734 SH   DFND 1 3,020,883 0 110,851
ZOOMINFO TECHNOLOGIES INC COM CL A 98980F104 4,551 74,373 SH   OTR 2 74,373 0 0
ZUMIEZ INC COM 989817101 1,110 27,922 SH   DFND 1 27,922 0 0