The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
89BIO INC COM 282559103 1,184 50,007 SH   SOLE   50,007 0 0
ACLARIS THERAPEUTICS INC COM 00461U105 8,486 336,737 SH   SOLE   336,737 0 0
ACTINIUM PHARMACEUTICALS INC COM 00507W206 350 45,910 SH   SOLE   45,910 0 0
ADAMAS PHARMACEUTICALS INC COM 00548A106 2,508 522,589 SH   SOLE   522,589 0 0
AFFIMED N V COM N01045108 3,973 502,330 SH   SOLE   502,330 0 0
AKERO THERAPEUTICS INC COM 00973Y108 928 32,000 SH   SOLE   32,000 0 0
ALDEYRA THERAPEUTICS INC COM 01438T106 3,824 321,879 SH   SOLE   321,879 0 0
AMRYT PHARMA PLC SPONSORED ADS 03217L106 5,988 429,863 SH   SOLE   429,863 0 0
APTOSE BIOSCIENCES INC COM NEW 03835T200 598 100,000 SH   SOLE   100,000 0 0
ARDELYX INC COM 039697107 298 45,000 SH   SOLE   45,000 0 0
ARENA PHARMACEUTICALS INC COM NEW 040047607 1,388 20,000 SH   SOLE   20,000 0 0
ARVINAS INC COM 04335A105 1,657 25,071 SH   SOLE   25,071 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101 2,409 18,694 SH   SOLE   18,694 0 0
BIOGEN INC COM 09062X103 2,798 10,000 SH Call SOLE   10,000 0 0
BIOGEN INC COM 09062X103 1,399 5,000 SH   SOLE   5,000 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 3,424 50,089 SH   SOLE   50,089 0 0
BIOLINERX LTD SPONSORED ADS 09071M205 558 200,000 SH   SOLE   200,000 0 0
BIOMX INC COM 09090D103 98 13,759 SH   SOLE   13,759 0 0
BLACK DIAMOND THERAPEUTICS I COM 09203E105 146 6,000 SH   SOLE   6,000 0 0
CALITHERA BIOSCIENCES INC COM 13089P101 73 30,000 SH   SOLE   30,000 0 0
CELLECTAR BIOSCIENCES INC COM PAR 15117F500 976 606,358 SH   SOLE   606,358 0 0
CHARDAN HEALTHCR ACQSTN 2 CO *W EXP 03/05/202 15957T115 93 98,756 SH   SOLE   98,756 0 0
CHEMOCENTRYX INC COM 16383L106 2,868 55,974 SH   SOLE   55,974 0 0
COHERUS BIOSCIENCES INC COM 19249H103 1,461 100,000 SH   SOLE   100,000 0 0
COMPUGEN LTD ORD M25722105 644 75,000 SH   SOLE   75,000 0 0
CURIS INC COM NEW 231269200 7,118 628,793 SH   SOLE   628,793 0 0
CYCLACEL PHARMACEUTICALS INC COM 23254L603 1,778 250,000 SH   SOLE   250,000 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 1,783 39,765 SH   SOLE   39,765 0 0
DELCATH SYS INC COM NEW 24661P807 497 40,000 SH   SOLE   40,000 0 0
DICERNA PHARMACEUTICALS INC COM 253031108 5,114 200,000 SH   SOLE   200,000 0 0
ESSA PHARMA INC COM NEW 29668H708 2,134 73,451 SH   SOLE   73,451 0 0
EVOGENE LTD SHS M4119S104 1,764 350,000 SH   SOLE   350,000 0 0
EYEPOINT PHARMACEUTICALS INC COM NEW 30233G209 3,048 300,000 SH   SOLE   300,000 0 0
FULCRUM THERAPEUTICS INC COM 359616109 1,429 121,302 SH   SOLE   121,302 0 0
GAMIDA CELL LTD SHS M47364100 189 23,393 SH   SOLE   23,393 0 0
GUARDANT HEALTH INC COM 40131M109 1,556 10,192 SH   SOLE   10,192 0 0
HALOZYME THERAPEUTICS INC COM 40637H109 4,375 104,945 SH   SOLE   104,945 0 0
HELIX ACQUISITION CORP COM CL A G4444C102 2,333 228,485 SH   SOLE   228,485 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 4,462 48,476 SH   SOLE   48,476 0 0
IMMATICS N.V SHS N44445109 469 41,797 SH   SOLE   41,797 0 0
IMMUNOGEN INC COM 45253H101 5,908 729,364 SH   SOLE   729,364 0 0
IMMUNOVANT INC COM 45258J102 808 50,400 SH   SOLE   50,400 0 0
INSMED INC COM PAR $.01 457669307 6,499 190,810 SH   SOLE   190,810 0 0
INTRA CELLULAR THERAPIES INC COM 46116X101 4,415 130,117 SH   SOLE   130,117 0 0
IVERIC BIO INC COM 46583P102 804 130,043 SH   SOLE   130,043 0 0
JOUNCE THERAPEUTICS INC COM 481116101 3,595 350,000 SH   SOLE   350,000 0 0
KALA PHARMACEUTICALS INC COM 483119103 689 102,198 SH   SOLE   102,198 0 0
KALVISTA PHARMACEUTICALS INC COM 483497103 1,285 50,000 SH   SOLE   50,000 0 0
KURA ONCOLOGY INC COM 50127T109 2,262 80,000 SH   SOLE   80,000 0 0
LARIMAR THERAPEUTICS INC COM 517125100 2,804 191,945 SH   SOLE   191,945 0 0
LEAP THERAPEUTICS INC COM 52187K101 570 300,000 SH   SOLE   300,000 0 0
MEDICENNA THERAPEUTICS CORP COM 58490H107 439 107,536 SH   SOLE   107,536 0 0
MEDICUS SCIENCES ACQUISITION UNIT 99/99/9999 G5960S116 4,007 406,791 SH   SOLE   406,791 0 0
MEREO BIOPHARMA GROUP PLC ADS 589492107 590 175,000 SH   SOLE   175,000 0 0
MERSANA THERAPEUTICS INC COM 59045L106 405 25,000 SH   SOLE   25,000 0 0
MERUS N V COM N5749R100 5,112 244,713 SH   SOLE   244,713 0 0
MIRATI THERAPEUTICS INC COM 60468T105 857 5,000 SH   SOLE   5,000 0 0
MORPHIC HLDG INC COM 61775R105 3,797 60,000 SH   SOLE   60,000 0 0
ODONATE THERAPEUTICS INC COM 676079106 1,710 500,000 SH   SOLE   500,000 0 0
ONCORUS INC COM 68236R103 1,810 130,000 SH   SOLE   130,000 0 0
OTONOMY INC COM 68906L105 640 250,995 SH   SOLE   250,995 0 0
PIERIS PHARMACEUTICALS INC COM 720795103 129 50,000 SH   SOLE   50,000 0 0
POLYPID LTD SHS M8001Q118 1,372 149,826 SH   SOLE   149,826 0 0
PROMETHEUS BIOSCIENCES INC COM 74349U108 274 15,000 SH   SOLE   15,000 0 0
RENALYTIX AI PLC ADS 75973T101 3,453 134,555 SH   SOLE   134,555 0 0
RESEARCH ALLIANCE CORP II COM CL A 760873109 5,125 500,000 SH   SOLE   500,000 0 0
ROCKET PHARMACEUTICALS INC COM 77313F106 444 10,000 SH   SOLE   10,000 0 0
SAGE THERAPEUTICS INC COM 78667J108 1,497 20,000 SH Call SOLE   20,000 0 0
SALARIUS PHARMACEUTICALS INC COM NEW 79400X107 2,948 1,992,181 SH   SOLE   1,992,181 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103 1,835 36,221 SH   SOLE   36,221 0 0
SEAGEN INC COM 81181C104 694 5,000 SH   SOLE   5,000 0 0
SERES THERAPEUTICS INC COM 81750R102 2,059 100,000 SH   SOLE   100,000 0 0
SIERRA ONCOLOGY INC COM NEW 82640U404 2,321 134,681 SH   SOLE   134,681 0 0
SOLENO THERAPEUTICS INC COM NEW 834203200 158 125,000 SH   SOLE   125,000 0 0
SURFACE ONCOLOGY INC COM 86877M209 780 100,000 SH   SOLE   100,000 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105 447 20,000 SH   SOLE   20,000 0 0
TCR2 THERAPEUTICS INC COM 87808K106 3,426 155,145 SH   SOLE   155,145 0 0
THERAPEUTICS ACQUISITION COR COM CL A 88339T103 420 40,000 SH   SOLE   40,000 0 0
TRAVERE THERAPEUTICS INC COM 89422G107 499 20,000 SH   SOLE   20,000 0 0
TRILLIUM THERAPEUTICS INC COM NEW 89620X506 644 60,000 SH   SOLE   60,000 0 0
TURNING POINT THERAPEUTICS I COM 90041T108 1,584 16,741 SH   SOLE   16,741 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102 897 5,364 SH   SOLE   5,364 0 0
UNUM THERAPEUTICS INC COM 19240Q201 1,054 120,000 SH   SOLE   120,000 0 0
VERACYTE INC COM 92337F107 3,225 60,000 SH   SOLE   60,000 0 0
VERASTEM INC COM 92337C104 2,958 1,197,489 SH   SOLE   1,197,489 0 0
VERICEL CORP COM 92346J108 6,784 122,125 SH   SOLE   122,125 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 1,612 7,500 SH   SOLE   7,500 0 0
VIRACTA THERAPEUTICS INC COM 92765F108 264 28,570 SH   SOLE   28,570 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104 461 27,586 SH   SOLE   27,586 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105 224 40,000 SH   SOLE   40,000 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105 561 100,000 SH Call SOLE   100,000 0 0