The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
AKOUOS INC COM 00973J101 10,768 858,027 SH   DFND   858,027 0 0
CORVUS PHARMACEUTICALS INC COM 221015100 1,920 719,132 SH   DFND   719,132 0 0
CULLINAN ONCOLOGY INC COM 230031106 57,753 2,242,841 SH   DFND   2,242,841 0 0
FREELINE THERAPEUTICS HLDGS SPONSORED ADS 35655L107 11,246 1,379,843 SH   DFND   1,379,843 0 0
G1 THERAPEUTICS INC COM 3621LQ109 1,097 50,000 SH   DFND   50,000 0 0
IKENA ONCOLOGY INC COM 45175G108 11,440 814,756 SH   DFND   814,756 0 0
INOZYME PHARMA INC COM 45790W108 15,801 927,264 SH   DFND   927,264 0 0
KEROS THERAPEUTICS INC COM 492327101 4,944 116,406 SH   DFND   116,406 0 0
KEZAR LIFE SCIENCES INC COM 49372L100 796 146,680 SH   DFND   146,680 0 0
LARIMAR THERAPEUTICS INC COM 517125100 14,879 1,515,148 SH   DFND   1,515,148 0 0
ONCORUS INC COM 68236R103 23,956 1,735,979 SH   DFND   1,735,979 0 0
ORCHARD THERAPEUTICS PLC ADS 68570P101 17,919 4,081,972 SH   DFND   4,081,972 0 0
OVID THERAPEUTICS INC COM 690469101 854 218,510 SH   DFND   218,510 0 0
PLIANT THERAPEUTICS INC COM 729139105 68,953 2,367,888 SH   DFND   2,367,888 0 0
PRECISION BIOSCIENCES INC COM 74019P108 8,160 651,729 SH   DFND   651,729 0 0
PROMETHEUS BIOSCIENCES INC COM 74349U108 70,046 2,852,009 SH   DFND   2,852,009 0 0
REPARE THERAPEUTICS INC COM 760273102 79,186 2,539,644 SH   DFND   2,539,644 0 0
VECTIVBIO HLDG AG ORD SHS H9060V101 30,152 2,585,986 SH   DFND   2,585,986 0 0