The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACUTUS MEDICAL INC COM 005111109 8,222 614,990 SH   SOLE   614,990 0 0
ADAMAS PHARMACEUTICALS INC COM 00548A106 8,019 1,670,600 SH   SOLE   1,670,600 0 0
AERPIO PHARMACEUTICALS INC COM 00810B105 1,290 1,000,000 SH   SOLE   1,000,000 0 0
ALPINE IMMUNE SCIENCES INC COM 02083G100 1,659 156,500 SH   SOLE   156,500 0 0
APTOSE BIOSCIENCES INC COM NEW 03835T200 5,209 871,800 SH   SOLE   871,800 0 0
AUTOLUS THERAPEUTICS PLC SPONSORED ADS 05280R100 12,107 2,112,918 SH   SOLE   2,112,918 0 0
AVEO BIOSCIENCES INC COM NEW 053588307 6,112 835,000 SH   SOLE   835,000 0 0
AYALA PHARMECEUTICALS INC COM 05465V108 1,184 108,551 SH   SOLE   108,551 0 0
BIOHAVEN PHARMACEUTICAL HLDG COM G11196105 1,709 25,000 SH   SOLE   25,000 0 0
BIOLINERX LTD SPONSORED ADS 09071M205 47 16,667 SH   SOLE   16,667 0 0
BRIDGEBIO PHARMA INC COM 10806X102 35,960 583,767 SH   SOLE   583,767 0 0
CATALYST BIOSCIENCES INC COM NEW 14888D208 6,300 1,250,000 SH   SOLE   1,250,000 0 0
CARDIFF ONCOLOGY INC COM 14147L108 5,334 576,000 SH   SOLE   576,000 0 0
CELLDEX THERAPEUTICS INC COM NEW 15117B202 20,291 985,000 SH   SOLE   985,000 0 0
CERECOR INC COM 15671L109 7,852 2,600,000 SH   SOLE   2,600,000 0 0
CHECKPOINT THERAPEUTICS INC COM 162828107 9,188 2,925,963 SH   SOLE   2,925,963 0 0
CHIMERIX INC COM 16934W106 43,284 4,490,000 SH   SOLE   4,490,000 0 0
CODEXIS INC COM 192005106 32,046 1,400,000 SH   SOLE   1,400,000 0 0
CONTRAFECT CORP COM NEW 212326300 1,171 244,000 SH   SOLE   244,000 0 0
CRINETICS PHARMACEUTICALS INC COM 22663K107 2,873 188,000 SH   SOLE   188,000 0 0
CYTOKINETICS INC COM NEW 23282W605 13,491 580,000 SH   SOLE   580,000 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 9,954 222,000 SH   SOLE   222,000 0 0
EDAP TMS SA SPONSORED ADR 268311107 2,867 341,300 SH   SOLE   341,300 0 0
ESSA PHARMA INC COM NEW 29668H708 8,252 284,050 SH   SOLE   284,050 0 0
ETON PHARMACEUTICALS INC COM 29772L108 29,573 4,040,000 SH   SOLE   4,040,000 0 0
FIBROGEN INC COM 31572Q808 5,102 147,000 SH   SOLE   147,000 0 0
FORTRESS BIOTECH INC COM 34960Q109 13,679 3,875,000 SH   SOLE   3,875,000 0 0
GEMINI THERAPEUTICS INC COM 36870G105 10,982 810,500 SH   SOLE   810,500 0 0
HARROW HEALTH INC COM 415858109 20,692 3,065,416 SH   SOLE   3,065,416 0 0
HIGHCAPE CAPITAL ACQUISITION CORP COM CL A 42984L105 2,876 241,300 SH   SOLE   241,300 0 0
IMMUNOVANT INC COM 45258J102 7,491 467,000 SH   SOLE   467,000 0 0
KEROS THERAPEUTICS INC COM 492327101 9,694 157,500 SH   SOLE   157,500 0 0
KEZAR LIFE SCIENCES INC COM 49372L100 4,239 711,200 SH   SOLE   711,200 0 0
KINIKSA PHARMACEUTICALS LTD COM CL A G5269C101 5,940 320,926 SH   SOLE   320,926 0 0
LEAP THERAPEUTICS INC COM 52187K101 737 388,100 SH   SOLE   388,100 0 0
LUMOS PHARMA INC COM 55028X109 4,410 376,900 SH   SOLE   376,900 0 0
MACROGENICS INC COM 556099109 21,218 666,200 SH   SOLE   666,200 0 0
MAGENTA THERAPEUTICS INC COM 55910K108 1,047 88,400 SH   SOLE   88,400 0 0
MEI PHARMA INC COM NEW 55279B202 5,337 1,556,000 SH   SOLE   1,556,000 0 0
MYOVANT SCIENCES LTD COM G637AM102 5,141 249,800 SH   SOLE   249,800 0 0
NEOLEUKIN THERAPEUTICS INC COM 64049K104 15,080 1,225,000 SH   SOLE   1,225,000 0 0
OCULAR THERAPEUTIX INC COM 67576A100 106,337 6,480,000 SH   SOLE   6,480,000 0 0
OPTINOSE INC COM 68404V100 3,048 826,000 SH   SOLE   826,000 0 0
PROQR THERAPEUTICS NV SHS EURO N71542109 8,613 1,303,000 SH   SOLE   1,303,000 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102 7,692 297,000 SH   SOLE   297,000 0 0
PROTARA THERAPEUTICS INC COM STK 74365U107 40,270 2,558,472 SH   SOLE   2,558,472 0 0
SANARA MEDTECH INC COM 79957L100 7,009 225,000 SH   SOLE   225,000 0 0
SERES THERAPEUTICS COM 81750R102 9,804 300,000 SH   SOLE   300,000 0 0
SIERRA ONCOLOGY INC COM NEW 82640U404 2,604 151,139 SH   SOLE   151,139 0 0
SIO GENE THERAPIES INC COM 829399104 5,220 2,000,000 SH   SOLE   2,000,000 0 0
STEREOTAXIS INC COM NEW 85916J409 16,978 2,526,500 SH   SOLE   2,526,500 0 0
SUTRO BIOPHARMA INC COM 869367102 7,783 341,950 SH   SOLE   341,950 0 0
TELA BIO INC COM 872381108 5,439 365,000 SH   SOLE   365,000 0 0
TRACON PHARMACEUTICALS INC COM NEW 89237H209 20,726 2,518,371 SH   SOLE   2,518,371 0 0
VAXCYTE INC COM 92243G108 7,067 357,800 SH   SOLE   357,800 0 0
VERASTEM INC COM 92337C104 5,743 2,325,000 SH   SOLE   2,325,000 0 0
VIRACTA THERAPEUTICS INC COM 92765F108 958 103,600 SH   SOLE   103,600 0 0
XOMA CORP DEL COM NEW 98419J206 17,854 437,500 SH   SOLE   437,500 0 0