The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8

COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
10X GENOMICS INC COMMON 88025U109 14 79 SH   DFND   79 0 0
1LIFE HEALTHCARE INC COMMON 68269G107 10,998 281,426 SH   DFND   259,717 0 21,709
1LIFE HEALTHCARE INC COMMON 68269G107 6,938 177,533 SH   DFND 2 177,533 0 0
21VIANET GROUP INC-ADR ADR 90138A103 2,961 91,668 SH   DFND   91,668 0 0
21VIANET GROUP INC-ADR ADR 90138A103 570 17,647 SH   DFND 2 17,647 0 0
2U INC COMMON 90214J101 11 281 SH   DFND   281 0 0
3M CO COMMON 88579Y101 22 114 SH   DFND   114 0 0
AARONS CO INC/THE COMMON 00258W108 10,590 412,390 SH   DFND   374,242 0 38,148
ABBOTT LABS COMMON 002824100 43,525 363,190 SH   DFND   360,928 0 2,262
ABBOTT LABS COMMON 002824100 2,439 20,351 SH   DFND 2 20,351 0 0
ABBVIE INC COMMON 00287Y109 50 459 SH   DFND   459 0 0
ABIOMED INC COMMON 003654100 14 43 SH   DFND   43 0 0
ACADIA HEALTHCARE CO INC COMMON 00404A109 14,688 257,049 SH   DFND   237,207 0 19,842
ACADIA HEALTHCARE CO INC COMMON 00404A109 9,261 162,084 SH   DFND 2 162,084 0 0
ACCENTURE LTD CL A COMMON G1151C101 304,711 1,103,028 SH   DFND   773,479 0 329,549
ACCENTURE LTD CL A COMMON G1151C101 2,619 9,480 SH   DFND 2 9,480 0 0
ACI WORLDWIDE INC COMMON 004498101 9,445 248,234 SH   DFND   228,102 0 20,132
ACTIVISION BLIZZARD INC COMMON 00507V109 848 9,113 SH   DFND   9,113 0 0
ACTIVISION BLIZZARD INC COMMON 00507V109 500 5,374 SH   DFND 2 5,374 0 0
ADAPTIVE BIOTECHNOLOGIES COMMON 00650F109 10 244 SH   DFND   244 0 0
ADDUS HOMECARE CORP COMMON 006739106 27,748 265,302 SH   DFND   261,088 0 4,214
ADDUS HOMECARE CORP COMMON 006739106 3,613 34,546 SH   DFND 2 34,546 0 0
ADOBE SYS COMMON 00724F101 338 710 SH   DFND   94 0 616
ADVANCED DRAINAGE SYSTEMS IN COMMON 00790R104 99,953 966,756 SH   DFND   938,488 0 28,268
ADVANCED DRAINAGE SYSTEMS IN COMMON 00790R104 22,978 222,250 SH   DFND 2 222,250 0 0
ADVANCED ENERGY INDS COMMON 007973100 86,570 792,979 SH   DFND   759,803 0 33,176
ADVANCED ENERGY INDS COMMON 007973100 21,307 195,175 SH   DFND 2 195,175 0 0
ADVANCED MICRO COMMON 007903107 232 2,959 SH   DFND   416 0 2,543
AECOM TECHNOLOGY CORP COMMON 00766T100 40,096 625,426 SH   DFND   356,633 0 268,793
AECOM TECHNOLOGY CORP COMMON 00766T100 2,537 39,578 SH   DFND 2 39,578 0 0
AERIE PHARMACEUTICALS CV BND 00771VAB4 2,690 150,550 SH   DFND   121,321 2,202 27,027
AERIE PHARMACEUTICALS CV BND 00771VAB4 1,064 59,539 SH   DFND 2 59,539 0 0
AERIE PHARMACEUTICALS INC COMMON 00771V108 30,200 1,690,009 SH   DFND   1,663,149 0 26,860
AERIE PHARMACEUTICALS INC COMMON 00771V108 3,933 220,091 SH   DFND 2 220,091 0 0
AEROJET ROCKETDYNE HOLDINGS INC COMMON 007800105 7,181 152,920 SH   DFND   138,315 0 14,605
AEROVIRONMENT INC COMMON 008073108 45,495 391,994 SH   DFND   385,765 0 6,229
AEROVIRONMENT INC COMMON 008073108 5,927 51,067 SH   DFND 2 51,067 0 0
AFLAC INC COMMON 001055102 10 203 SH   DFND   203 0 0
AGREE REALTY CORP COMMON 008492100 26,909 399,773 SH   DFND   243,257 0 156,516
AGREE REALTY CORP COMMON 008492100 1,485 22,057 SH   DFND 2 22,057 0 0
AIR PRODS & CHEM COMMON 009158106 23 80 SH   DFND   80 0 0
AIR TRANSPORT SERVICES GROUP I COMMON 00922R105 40,257 1,375,851 SH   DFND   1,353,985 0 21,866
AIR TRANSPORT SERVICES GROUP I COMMON 00922R105 5,243 179,176 SH   DFND 2 179,176 0 0
AIRBNB INC COMMON 009066101 213,158 1,134,181 SH   DFND   743,161 0 391,020
ALAMO GROUP INC COMMON 011311107 18,959 121,414 SH   DFND   111,003 0 10,411
ALBANY INTL CORP-CL A COMMON 012348108 47,777 572,380 SH   DFND   553,076 0 19,304
ALBANY INTL CORP-CL A COMMON 012348108 4,699 56,290 SH   DFND 2 56,290 0 0
ALBEMARLE CORP COMMON 012653101 13 92 SH   DFND   92 0 0
ALIBABA GROUP HOLDING-SP ADR ADR 01609W102 2,614,813 11,532,718 SH   DFND   8,934,195 0 2,598,523
ALIBABA GROUP HOLDING-SP ADR ADR 01609W102 167,600 739,205 SH   DFND 2 739,205 0 0
ALIGN TECHNOLOGY INC COMMON 016255101 14 25 SH   DFND   25 0 0
ALLEGION PLC COMMON G0176J109 12,438 99,015 SH   DFND   30,471 0 68,544
ALLEGION PLC COMMON G0176J109 1,483 11,807 SH   DFND 2 11,807 0 0
ALLETE INC COMMON 018522300 13,521 201,239 SH   DFND   183,041 0 18,198
ALLSCRIPTS INC COMMON 01988P108 18,353 1,222,311 SH   DFND   897,636 0 324,675
ALLSTATE CORP COMMON 020002101 802 6,983 SH   DFND   5,243 0 1,740
ALLSTATE CORP COMMON 020002101 364 3,164 SH   DFND 2 3,164 0 0
ALPHABET INC-CL A COMMON 02079K305 2,064,178 1,000,804 SH   DFND   771,517 0 229,287
ALPHABET INC-CL A COMMON 02079K305 119,808 58,088 SH   DFND 2 58,088 0 0
ALPHABET INC-CL C COMMON 02079K107 1,675,996 810,196 SH   DFND   634,859 0 175,337
ALPHABET INC-CL C COMMON 02079K107 114,857 55,523 SH   DFND 2 55,523 0 0
ALTA EQUIPMENT GROUP INC COMMON 02128L106 6,422 494,012 SH   DFND   449,661 0 44,351
ALTRA INDUSTRIAL MOTION CORP COMMON 02208R106 30,033 542,892 SH   DFND   349,045 0 193,847
ALTRA INDUSTRIAL MOTION CORP COMMON 02208R106 1,423 25,725 SH   DFND 2 25,725 0 0
ALTRIA GROUP INC COMMON 02209S103 1,001 19,572 SH   DFND   19,572 0 0
ALTRIA GROUP INC COMMON 02209S103 617 12,063 SH   DFND 2 12,063 0 0
AMAZON.COM INC COMMON 023135106 4,103,350 1,326,194 SH   DFND   1,032,911 0 293,283
AMAZON.COM INC COMMON 023135106 251,775 81,373 SH   DFND 2 81,373 0 0
AMBEV SA-SPN ADR ADR 02319V103 43,720 15,956,125 SH   DFND   15,628,409 0 327,716
AMBEV SA-SPN ADR ADR 02319V103 2,303 840,572 SH   DFND 2 840,572 0 0
AMCOR PLC COMMON G0250X107 11 927 SH   DFND   927 0 0
AMEDISYS INC COMMON 023436108 22,829 86,216 SH   DFND   84,847 0 1,369
AMEDISYS INC COMMON 023436108 2,969 11,213 SH   DFND 2 11,213 0 0
AMERICAN AIRLINES GROUP INC COMMON 02376R102 22 931 SH   DFND   931 0 0
AMERICAN ELEC PWR COMMON 025537101 31 369 SH   DFND   369 0 0
AMERICAN FINANCIAL GROUP INC COMMON 025932104 20 178 SH   DFND   178 0 0
AMERICAN HOMES 4 RENT- A COMMON 02665T306 7 213 SH   DFND   213 0 0
AMERICAN INTL GRP INC COMMON 026874784 13 275 SH   DFND   275 0 0
AMERICAN TOWER CORPORATION COMMON 03027X100 44,572 186,445 SH   DFND   185,146 0 1,299
AMERICAN TOWER CORPORATION COMMON 03027X100 2,713 11,348 SH   DFND 2 11,348 0 0
AMERICAN WATER WORKS CO INC COMMON 030420103 16,080 107,255 SH   DFND   33,585 0 73,670
AMERICAN WATER WORKS CO INC COMMON 030420103 1,828 12,196 SH   DFND 2 12,196 0 0
AMERICAN WOODMARK CORP COMMON 030506109 12,660 128,422 SH   DFND   116,609 0 11,813
AMERICOLD REALTY TRUST COMMON 03064D108 29,713 772,361 SH   DFND   465,633 0 306,728
AMERICOLD REALTY TRUST COMMON 03064D108 1,782 46,321 SH   DFND 2 46,321 0 0
AMERIPRISE FINANCIAL INC COMMON 03076C106 11 46 SH   DFND   46 0 0
AMERIS BANCORP COMMON 03076K108 56,325 1,072,652 SH   DFND   1,029,465 0 43,187
AMERIS BANCORP COMMON 03076K108 4,816 91,718 SH   DFND 2 91,718 0 0
AMERISOURCEBERGEN CORP COMMON 03073E105 11 91 SH   DFND   91 0 0
AMGEN INC COMMON 031162100 38 151 SH   DFND   151 0 0
AMN HEALTHCARE SERVICES INC COMMON 001744101 12,621 171,244 SH   DFND   86,502 0 84,742
AMN HEALTHCARE SERVICES INC COMMON 001744101 1,019 13,829 SH   DFND 2 13,829 0 0
AMPHENOL CORP CL A COMMON 032095101 28 423 SH   DFND   423 0 0
ANALOG DEVICES INC COMMON 032654105 23 146 SH   DFND   146 0 0
ANSYS INC COMMON 03662Q105 129 379 SH   DFND 2 379 0 0
ANTERO MIDSTREAM CORP COMMON 03676B102 30 3,370 SH   DFND   3,370 0 0
ANTHEM INC COMMON 036752103 44,624 124,317 SH   DFND   123,433 0 884
ANTHEM INC COMMON 036752103 2,835 7,898 SH   DFND 2 7,898 0 0
APPLE HOSPITALITY REIT INC COMMON 03784Y200 1 54 SH   DFND   54 0 0
APPLE INC COMMON 037833100 47,989 392,871 SH   DFND   382,572 0 10,299
APPLE INC COMMON 037833100 4,026 32,959 SH   DFND 2 32,959 0 0
APPLIED MATERIALS COMMON 038222105 1,036 7,756 SH   DFND   7,756 0 0
APPLIED MATERIALS COMMON 038222105 642 4,809 SH   DFND 2 4,809 0 0
ARCHER-DANIELS-MIDLAND CO COMMON 039483102 16 280 SH   DFND   280 0 0
ARCOSA INC COMMON 039653100 40,481 621,923 SH   DFND   394,228 0 227,695
ARCOSA INC COMMON 039653100 1,997 30,682 SH   DFND 2 30,682 0 0
ARES MANAGEMENT CORP - A COMMON 03990B101 27,532 491,376 SH   DFND   453,468 0 37,908
ARES MANAGEMENT CORP - A COMMON 03990B101 17,371 310,029 SH   DFND 2 310,029 0 0
ARGENX SE - ADR ADR 04016X101 11,169 40,556 SH   DFND   37,426 0 3,130
ARGENX SE - ADR ADR 04016X101 7,043 25,573 SH   DFND 2 25,573 0 0
ARMATA PHARMACEUTICALS INC COMMON 04216R102 621 129,956 SH   DFND   129,956 0 0
ARMSTRONG WORLD INDUSTRIES COMMON 04247X102 7,141 79,269 SH   DFND   72,506 0 6,763
ARTISAN PARTNERS ASSET MGMT CL A COMMON 04316A108 927 17,774 SH   DFND   17,774 0 0
ARTISAN PARTNERS ASSET MGMT CL A COMMON 04316A108 587 11,249 SH   DFND 2 11,249 0 0
ASCENDIS PHARMA A/S - ADR ADR 04351P101 13,588 105,433 SH   DFND   97,297 0 8,136
ASCENDIS PHARMA A/S - ADR ADR 04351P101 8,654 67,151 SH   DFND 2 67,151 0 0
ASHLAND GLOBAL HOLDINGS INC COMMON 044186104 15,474 174,317 SH   DFND   133,336 0 40,981
ASHLAND GLOBAL HOLDINGS INC COMMON 044186104 1,199 13,505 SH   DFND 2 13,505 0 0
ASSETMARK FINANCIAL HOLDINGS COMMON 04546L106 33,612 1,440,106 SH   DFND   1,417,217 0 22,889
ASSETMARK FINANCIAL HOLDINGS COMMON 04546L106 4,378 187,569 SH   DFND 2 187,569 0 0
ASSURANT INC COMMON 04621X108 10 74 SH   DFND   74 0 0
AT&T INC COMMON 00206R102 3,852 127,267 SH   DFND   127,267 0 0
ATHENE HOLDING LTD-CLASS A COMMON G0684D107 116 2,307 SH   DFND   0 0 2,307
ATKORE INTERNATIONAL GROUP I COMMON 047649108 8,396 116,780 SH   DFND   105,610 0 11,170
ATLANTIC CAPITAL BANCSHARES COMMON 048269203 6,289 260,952 SH   DFND   84,153 0 176,799
ATLANTIC CAPITAL BANCSHARES COMMON 048269203 751 31,151 SH   DFND 2 31,151 0 0
ATLANTIC UNION BANKSHARES CORP COMMON 04911A107 16,840 439,009 SH   DFND   400,936 0 38,073
ATLAS AIR WORLDWIDE HLDG CVT CV BND 049164BJ4 13,135 217,329 SH   DFND   171,899 0 45,430
ATLAS AIR WORLDWIDE HLDG CVT CV BND 049164BJ4 9,454 156,428 SH   DFND 2 156,428 0 0
ATRICURE INC COMMON 04963C209 53,329 813,933 SH   DFND   800,997 0 12,936
ATRICURE INC COMMON 04963C209 6,941 105,935 SH   DFND 2 105,935 0 0
AUTODESK INC COMMON 052769106 2,490,298 8,985,379 SH   DFND   7,051,437 0 1,933,942
AUTODESK INC COMMON 052769106 171,846 620,046 SH   DFND 2 620,046 0 0
AUTOMATIC DATA PROC COMMON 053015103 435,278 2,309,536 SH   DFND   1,851,446 0 458,090
AUTOMATIC DATA PROC COMMON 053015103 28,988 153,806 SH   DFND 2 153,806 0 0
AUTOZONE INC COMMON 053332102 13 9 SH   DFND   9 0 0
AVALARA INC COMMON 05338G106 14,679 110,014 SH   DFND   101,524 0 8,490
AVALARA INC COMMON 05338G106 9,342 70,011 SH   DFND 2 70,011 0 0
AVANTOR INC COMMON 05352A100 19,967 690,196 SH   DFND   214,235 0 475,961
AVANTOR INC COMMON 05352A100 2,339 80,866 SH   DFND 2 80,866 0 0
AVAYA HOLDINGS CORP COMMON 05351X101 0 1 SH   DFND   1 0 0
AXON ENTERPRISE INC COMMON 05464C101 23,971 168,310 SH   DFND   155,333 0 12,977
AXON ENTERPRISE INC COMMON 05464C101 15,116 106,136 SH   DFND 2 106,136 0 0
AXONICS MODULATION TECHNOLOG COMMON 05465P101 53,975 901,230 SH   DFND   886,910 0 14,320
AXONICS MODULATION TECHNOLOG COMMON 05465P101 7,029 117,361 SH   DFND 2 117,361 0 0
AXOS FINANCIAL INC COMMON 05465C100 9,821 208,910 SH   DFND   192,780 0 16,130
AXOS FINANCIAL INC COMMON 05465C100 6,196 131,797 SH   DFND 2 131,797 0 0
AZZ INC COMMON 002474104 4,665 92,661 SH   DFND   84,305 0 8,356
BAIDU.COM ADR 056752108 60,444 277,841 SH   DFND   271,210 0 6,631
BAIDU.COM ADR 056752108 3,314 15,235 SH   DFND 2 15,235 0 0
BAKER HUGHS CO COMMON 05722G100 14 661 SH   DFND   661 0 0
BANCORP INC COMMON 05969A105 29,807 1,438,575 SH   DFND   1,415,711 0 22,864
BANCORP INC COMMON 05969A105 3,877 187,096 SH   DFND 2 187,096 0 0
BANCORPSOUTH INC COMMON 05971J102 13,926 428,756 SH   DFND   393,016 0 35,740
BANK OF AMERICA CORP COMMON 060505104 1,036 26,771 SH   DFND   26,771 0 0
BANK OF AMERICA CORP COMMON 060505104 608 15,712 SH   DFND 2 15,712 0 0
BANK OF NEW YORK MELLON CORP COMMON 064058100 11 224 SH   DFND   224 0 0
BAOZUN INC-SPN ADR ADR 06684L103 9 237 SH   DFND   237 0 0
BAOZUN INC-SPN ADR ADR 06684L103 5 141 SH   DFND 2 141 0 0
BATTALION OIL CORP COMMON 07134L107 3,482 320,035 SH   DFND   292,463 5,288 22,284
BATTALION OIL CORP COMMON 07134L107 450 41,352 SH   DFND 2 41,352 0 0
BAXTER INTL COMMON 071813109 21 252 SH   DFND   252 0 0
BECTON DICKINSON & CO COMMON 075887109 95,015 390,765 SH   DFND   253,221 0 137,544
BERKSHIRE HATHAWAY INC CL B COMMON 084670702 133 522 SH   DFND   243 0 279
BILL.COM HOLDINGS INC COMMON 090043100 14 98 SH   DFND   98 0 0
BIO-TECHNE CORPORAT COMMON 09073M104 22,040 57,708 SH   DFND   53,256 0 4,452
BIO-TECHNE CORPORAT COMMON 09073M104 13,901 36,397 SH   DFND 2 36,397 0 0
BIOGEN INC COMMON 09062X103 11 40 SH   DFND   40 0 0
BIOMARIN PHARMACEUTICAL CVT CV BND 09061GAH4 43,522 576,379 SH   DFND   525,244 1,885 49,250
BIOMARIN PHARMACEUTICAL CVT CV BND 09061GAH4 7,679 101,701 SH   DFND 2 101,701 0 0
BIOMARIN PHARMACEUTICAL INC COMMON 09061G101 37,977 502,942 SH   DFND   406,678 0 96,264
BIOMARIN PHARMACEUTICAL INC COMMON 09061G101 978 12,957 SH   DFND 2 12,957 0 0
BLACK KNIGHT INC COMMON 09215C105 12,836 173,480 SH   DFND   160,083 0 13,397
BLACK KNIGHT INC COMMON 09215C105 8,098 109,452 SH   DFND 2 109,452 0 0
BLACKLINE INC COMMON 09239B109 56,181 518,279 SH   DFND   499,442 0 18,837
BLACKLINE INC COMMON 09239B109 16,708 154,131 SH   DFND 2 154,131 0 0
BLACKROCK INC COMMON 09247X101 43,215 57,317 SH   DFND   56,933 0 384
BLACKROCK INC COMMON 09247X101 1,996 2,648 SH   DFND 2 2,648 0 0
BLACKSTONE MORTGAGE TR CVT CV BND 09257WAB6 2,824 91,105 SH   DFND   91,105 0 0
BLUEPRINT MEDICINES CORP COMMON 09627Y109 34,706 356,950 SH   DFND   351,277 0 5,673
BLUEPRINT MEDICINES CORP COMMON 09627Y109 4,517 46,452 SH   DFND 2 46,452 0 0
BOEING CO COMMON 097023105 2,773,980 10,890,309 SH   DFND   8,811,030 0 2,079,279
BOEING CO COMMON 097023105 193,952 761,433 SH   DFND 2 761,433 0 0
BOOKING HOLDINGS INC COMMON 09857L108 1,608 690 SH   DFND   690 0 0
BOOKING HOLDINGS INC COMMON 09857L108 1,020 438 SH   DFND 2 438 0 0
BOOT BARN HOLDINGS INC COMMON 099406100 30,888 495,709 SH   DFND   487,831 0 7,878
BOOT BARN HOLDINGS INC COMMON 099406100 4,014 64,422 SH   DFND 2 64,422 0 0
BOOZ ALLEN HAMILTON HOLDING COMMON 099502106 3,425 42,526 SH   DFND   21,983 0 20,543
BOOZ ALLEN HAMILTON HOLDING COMMON 099502106 558 6,933 SH   DFND 2 6,933 0 0
BORG WARNER INC COMMON 099724106 10,490 226,276 SH   DFND   69,050 0 157,226
BORG WARNER INC COMMON 099724106 1,163 25,094 SH   DFND 2 25,094 0 0
BOSTON BEER COMPANY CL A COMMON 100557107 17 14 SH   DFND   14 0 0
BOSTON SCIENTIFIC CORP COMMON 101137107 20 512 SH   DFND   512 0 0
BRANDYWINE RLTY TRUST COMMON 105368203 6 472 SH   DFND   472 0 0
BRISTOL MYERS SQUIBB COMMON 110122108 333,171 5,277,533 SH   DFND   5,274,262 0 3,271
BRISTOL MYERS SQUIBB COMMON 110122108 556 8,806 SH   DFND 2 8,806 0 0
BROADCOM INC COMMON 11135F101 30 64 SH   DFND   64 0 0
BROADRIDGE FINANCIAL SOLUTIONS INC COMMON 11133T103 17,878 116,776 SH   DFND   107,764 0 9,012
BROADRIDGE FINANCIAL SOLUTIONS INC COMMON 11133T103 11,278 73,666 SH   DFND 2 73,666 0 0
BRUNSWICK CORP COMMON 117043109 41,935 439,710 SH   DFND   403,987 0 35,723
BRUNSWICK CORP COMMON 117043109 15,901 166,727 SH   DFND 2 166,727 0 0
BRYN MAWR BANK CORP COMMON 117665109 16,581 364,336 SH   DFND   334,058 0 30,278
BURLINGTON STORES INC COMMON 122017106 171 571 SH   DFND 2 571 0 0
BWX TECHNOLOGIES INC COMMON 05605H100 11,467 173,894 SH   DFND   157,673 0 16,221
CABOT CORP COMMON 127055101 10,673 203,527 SH   DFND   186,471 0 17,056
CADENCE DESIGN SYS INC COMMON 127387108 42 305 SH   DFND   305 0 0
CALIFORNIA RESOURCES CORP COMMON 13057Q305 1,466 60,950 SH   DFND   60,950 0 0
CALIFORNIA RESOURCES CORP COMMON 13057Q305 558 23,178 SH   DFND 2 23,178 0 0
CANNAE HOLDINGS INC COMMON 13765N107 13,935 351,711 SH   DFND   320,869 0 30,842
CAPITAL ONE FINL CORP COMMON 14040H105 18 142 SH   DFND   142 0 0
CARETRUST REIT INC COMMON 14174T107 6 253 SH   DFND   253 0 0
CARMAX INC COMMON 143130102 25 190 SH   DFND   190 0 0
CARNIVAL CORP CL A COMMON 143658300 20 759 SH   DFND   759 0 0
CARVANA CO COMMON 146869102 13 50 SH   DFND   50 0 0
CASELLA WASTE SYSTEMS INC CL A COMMON 147448104 58,077 913,586 SH   DFND   899,067 0 14,519
CASELLA WASTE SYSTEMS INC CL A COMMON 147448104 7,564 118,987 SH   DFND 2 118,987 0 0
CASEYS GENERAL STORES INC COMMON 147528103 17,593 81,377 SH   DFND   75,096 0 6,281
CASEYS GENERAL STORES INC COMMON 147528103 11,095 51,322 SH   DFND 2 51,322 0 0
CATALENT INC COMMON 148806102 55,258 524,719 SH   DFND   361,520 0 163,199
CATALENT INC COMMON 148806102 16,845 159,955 SH   DFND 2 159,955 0 0
CATERPILLAR COMMON 149123101 26 113 SH   DFND   113 0 0
CDK GLOBAL INC COMMON 12508E101 12,768 236,180 SH   DFND   71,244 0 164,936
CDK GLOBAL INC COMMON 12508E101 1,405 25,991 SH   DFND 2 25,991 0 0
CELANESE CORP A COMMON 150870103 11 71 SH   DFND   71 0 0
CEMEX SA-SPONS ADR ADR 151290889 6,879 986,948 SH   DFND   986,948 0 0
CEMEX SA-SPONS ADR ADR 151290889 3,629 520,684 SH   DFND 2 520,684 0 0
CENTENE CORP COMMON 15135B101 20 319 SH   DFND   319 0 0
CENTERSPACE COMMON 15202L107 3 38 SH   DFND   38 0 0
CERNER CORP COMMON 156782104 788,595 10,970,988 SH   DFND   8,657,451 0 2,313,537
CERNER CORP COMMON 156782104 52,621 732,061 SH   DFND 2 732,061 0 0
CHAMPIONX CORP COMMON 15872M104 30,555 1,406,110 SH   DFND   1,048,760 0 357,350
CHAMPIONX CORP COMMON 15872M104 1,025 47,159 SH   DFND 2 47,159 0 0
CHANNELADVISOR CORP COMMON 159179100 6,495 275,776 SH   DFND   88,306 0 187,470
CHANNELADVISOR CORP COMMON 159179100 759 32,223 SH   DFND 2 32,223 0 0
CHARLES RIVER LABS COMMON 159864107 20,137 69,480 SH   DFND   64,119 0 5,361
CHARLES RIVER LABS COMMON 159864107 12,699 43,816 SH   DFND 2 43,816 0 0
CHART INDUSTRIES INC COMMON 16115Q308 19,542 137,278 SH   DFND   42,899 0 94,379
CHART INDUSTRIES INC COMMON 16115Q308 2,228 15,653 SH   DFND 2 15,653 0 0
CHARTER COMMUNICATIONS INC-A COMMON 16119P108 39 64 SH   DFND   64 0 0
CHEGG INC COMMON 163092109 17,352 202,574 SH   DFND   186,956 0 15,618
CHEGG INC COMMON 163092109 10,938 127,695 SH   DFND 2 127,695 0 0
CHEMED CORP COMMON 16359R103 15,724 34,197 SH   DFND   31,558 0 2,639
CHEMED CORP COMMON 16359R103 9,913 21,558 SH   DFND 2 21,558 0 0
CHEMOCENTRYX INC COMMON 16383L106 34,853 680,182 SH   DFND   661,718 0 18,464
CHEMOCENTRYX INC COMMON 16383L106 7,741 151,082 SH   DFND 2 151,082 0 0
CHESAPEAKE ENERGY CORP COMMON 165167735 29 678 SH   DFND   678 0 0
CHESAPEAKE ENERGY CORP -CW26 WTS 165167180 22 1,280 SH   DFND   1,280 0 0
CHEVRON CORP COMMON 166764100 43,823 418,203 SH   DFND   413,605 0 4,598
CHEVRON CORP COMMON 166764100 2,531 24,156 SH   DFND 2 24,156 0 0
CHEWY INC - CLASS A COMMON 16679L109 55 653 SH   DFND   0 0 653
CHIPOTLE MEXICAN GRILL INC COMMON 169656105 33 23 SH   DFND   23 0 0
CHUBB LIMITED COMMON H1467J104 21 130 SH   DFND   130 0 0
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NIC INC COMMON 62914B100 6,006 177,005 SH   DFND 2 177,005 0 0
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NOMAD FOODS LTD COMMON G6564A105 1,917 69,805 SH   DFND 2 69,805 0 0
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NOVARTIS AG SPON ADR ADR 66987V109 111,111 1,299,847 SH   DFND 2 1,299,847 0 0
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NRG ENERGY INC CVT CV BND 629377CG5 11,204 296,943 SH   DFND   280,180 0 16,763
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NXP SEMICONDUCTORS NV COMMON N6596X109 3,185 15,818 SH   DFND 2 15,818 0 0
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ON SEMICONDUCTOR CORPORATION COMMON 682189105 17,637 423,871 SH   DFND   133,717 0 290,154
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PACIFIC PREMIER BANCORP INC COMMON 69478X105 9,676 222,746 SH   DFND 2 222,746 0 0
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PACKAGING CORP OF AMERICA COMMON 695156109 1,276 9,491 SH   DFND 2 9,491 0 0
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