The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACHILLES THERAPEUTICS PLC SPONSORED ADS 00449L102 22,986 1,388,888 SH   SOLE   1,388,888 0 0
ADVERUM BIOTECHNOLOGIES INC COM 00773U108 92,347 9,365,833 SH   SOLE   9,365,833 0 0
AKOUOS INC COM 00973J101 31,641 2,281,249 SH   SOLE   2,281,249 0 0
ARDELYX INC COM 039697107 40,232 6,077,294 SH   SOLE   6,077,294 0 0
ARYA SCIENCES ACQUISITION CO COM CL A G3166W106 13,386 971,430 SH   SOLE   971,430 0 0
ARYA SCIENCES ACQU CORP IV CL A G31659108 10,473 1,000,000 SH   SOLE   1,000,000 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101 826,408 6,412,228 SH   SOLE   6,412,228 0 0
ATEA PHARMACEUTICALS INC COM 04683R106 331,502 5,368,451 SH   SOLE   5,368,451 0 0
AXSOME THERAPEUTICS INC COM 05464T104 93,731 1,655,447 SH   SOLE   1,655,447 0 0
BCTG ACQUISITION CORP COM 05492W103 13,900 1,250,000 SH   SOLE   1,250,000 0 0
BLACK DIAMOND THERAPEUTICS INC COM 09203E105 62,831 2,589,904 SH   SOLE   2,589,904 0 0
BCLS ACQUISITION CORP COM CL A G0904B105 13,213 1,250,000 SH   SOLE   1,250,000 0 0
BOLT BIOTHERAPEUTICS INC COM 097702104 78,271 2,378,325 SH   SOLE   2,378,325 0 0
C4 THERAPEUTICS INC COM STK 12529R107 50,956 1,377,569 SH   SOLE   1,377,569 0 0
CHEMOCENTRYX INC COM 16383L106 182,251 3,556,810 SH   SOLE   3,556,810 0 0
CEREVEL THERAPEUTICS HLDNG INC COM 15678U128 30,206 2,200,000 SH   SOLE   2,200,000 0 0
CEREVEL THERAPEUTICS HLDNG INC *W EXP 06/09/2027 15678U102 1,006 233,333 SH   SOLE   233,333 0 0
CULLINAN ONCOLOGY INC COM COM 230031106 14,585 350,000 SH   SOLE   350,000 0 0
CONCERT PHARMACEUTICALS INC COM 206022105 15,138 3,033,603 SH   SOLE   3,033,603 0 0
CONSTELLATION PHARMCETICLS INC COM 210373106 52,359 2,238,536 SH   SOLE   2,238,536 0 0
CONNECT BIOPHARMA HLDGS LTD ADS 207523101 55,337 2,991,208 SH   SOLE   2,991,208 0 0
COGENT BIOSCIENCES INC COM 19240Q201 9,005 1,025,641 SH   SOLE   1,025,641 0 0
CURIS INC COM NEW 231269200 80,826 7,140,091 SH   SOLE   7,140,091 0 0
CYTOMX THERAPEUTICS INC COM 23284F105 27,055 3,500,000 SH   SOLE   3,500,000 0 0
DESIGN THERAPEUTICS INC COM 25056L103 65,380 2,186,636 SH   SOLE   2,186,636 0 0
DYNE THERAPEUTICS INC COM 26818M108 43,562 2,805,045 SH   SOLE   2,805,045 0 0
89BIO INC COM 282559103 112,154 4,736,214 SH   SOLE   4,736,214 0 0
EDGEWISE THERAPEUTICS INC COM 28036F105 84,943 2,613,623 SH   SOLE   2,613,623 0 0
EYEPOINT PHARMACEUTICALS INC COM NEW 30233G209 12,700 1,250,000 SH   SOLE   1,250,000 0 0
FRAZIER LIFESCIENCES ACQUISITION CO UNIT 12/09/2025 G3710A121 10,160 1,000,000 SH   SOLE   1,000,000 0 0
FORMA THERAPEUTICS HLDGS INC SHS 34633R104 252,506 9,011,651 SH   SOLE   9,011,651 0 0
FS DEVELOPMENT CORP II COM CL A 30318F100 9,960 1,000,000 SH   SOLE   1,000,000 0 0
5 01 ACQUISITION CORP COM CL A 33836P105 7,463 750,000 SH   SOLE   750,000 0 0
GERON CORP COM 374163103 47,600 30,126,299 SH   SOLE   30,126,299 0 0
HELIX ACQUISITION CORP COM CL A G4444C102 7,147 700,000 SH   SOLE   700,000 0 0
HEALTH SCIENCES ACQ CORP 2 ORD SHS G4411D109 6,994 625,000 SH   SOLE   625,000 0 0
IGM BIOSCIENCES INC COM 449585108 75,365 982,723 SH   SOLE   982,723 0 0
IKENA ONCOLOGY INC COM 45175G108 21,188 750,000 SH   SOLE   750,000 0 0
IMMUNOGEN INC COM 45253H101 149,181 18,417,458 SH   SOLE   18,417,458 0 0
IMARA INC COM 45249V107 2,100 248,804 SH   SOLE   248,804 0 0
INOZYME PHARMA INC COM 45790W108 39,672 2,003,653 SH   SOLE   2,003,653 0 0
ITEOS THERAPEUTICS INC COM 46565G104 150,982 4,417,258 SH   SOLE   4,417,258 0 0
KALA PHARMACEUTICALS INC COM 483119103 73,295 10,874,613 SH   SOLE   10,874,613 0 0
KALVISTA PHARMACEUTICALS INC COM 483497103 8,992 350,000 SH   SOLE   350,000 0 0
KINNATE BIOPHARMA INC COM 49705R105 111,960 3,593,052 SH   SOLE   3,593,052 0 0
LARIMAR THERAPEUTICS INC COM 517125100 22,136 1,515,151 SH   SOLE   1,515,151 0 0
SERES THERAPEUTICS INC COM 81750R102 76,063 3,694,193 SH   SOLE   3,694,193 0 0
MACROGENICS INC COM 556099109 157,135 4,933,594 SH   SOLE   4,933,594 0 0
MILESTONE PHARMACEUTICALS INC COM 59935V107 13,007 2,246,503 SH   SOLE   2,246,503 0 0
NKARTA INC COM 65487U108 184,409 5,605,129 SH   SOLE   5,605,129 0 0
NOVAVAX INC COM NEW 670002401 544,308 3,002,087 SH   SOLE   3,002,087 0 0
OCULAR THERAPEUTIX INC COM 67576A100 12,308 750,000 SH   SOLE   750,000 0 0
OLEMA PHARMACEUTICALS INC COM 68062P106 71,350 2,150,404 SH   SOLE   2,150,404 0 0
ORIC PHARMACEUTICALS INC COM 68622P109 14,308 584,000 SH   SOLE   584,000 0 0
ORCHARD THERAPEUTICS PLC ADS 68570P101 69,164 12,315,213 SH   SOLE   12,315,213 0 0
VAXCYTE INC COM 92243G108 76,350 3,865,808 SH   SOLE   3,865,808 0 0
PHASEBIO PHARMACEUTICALS INC COM 717224109 9,861 2,850,000 SH   SOLE   2,850,000 0 0
PHATHOM PHARMACEUTICALS INC COM 71722W107 117,000 3,115,008 SH   SOLE   3,115,008 0 0
PMV PHARMACEUTICALS INC COM 69353Y103 56,251 1,710,265 SH   SOLE   1,710,265 0 0
PROQR THERAPEUTICS N V SHS EURO N71542109 13,998 2,117,669 SH   SOLE   2,117,669 0 0
ROCKET PHARMACEUTICALS INC COM COM 77313F106 93,494 2,107,149 SH   SOLE   2,107,149 0 0
RELAY THERAPEUTICS INC COM 75943R102 34,570 1,000,000 SH   SOLE   1,000,000 0 0
REPARE THERAPEUTICS INC COM 760273102 12,552 409,000 SH   SOLE   409,000 0 0
RHYTHM PHARMACEUTICALS INC COM 76243J105 103,608 4,871,067 SH   SOLE   4,871,067 0 0
SILVERBACK THERAPEUTICS INC COM 82835W108 76,012 1,742,186 SH   SOLE   1,742,186 0 0
SCPHARMACEUTICALS INC COM 810648105 18,162 2,731,170 SH   SOLE   2,731,170 0 0
SOLID BIOSCIENCES INC COM 83422E105 68,394 12,367,873 SH   SOLE   12,367,873 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105 22,876 1,023,067 SH   SOLE   1,023,067 0 0
SUTRO BIOPHARMA INC COM 869367102 48,211 2,118,212 SH   SOLE   2,118,212 0 0
SATSUMA PHARMACEUTICALS INC COM 80405P107 34,953 5,914,252 SH   SOLE   5,914,252 0 0
SYROS PHARMACEUTICALS INC COM 87184Q107 6,732 900,000 SH   SOLE   900,000 0 0
TG THERAPEUTICS INC COM 88322Q108 223,462 4,636,146 SH   SOLE   4,636,146 0 0
INSTIL BIO INC COM 45783C101 122,159 4,870,793 SH   SOLE   4,870,793 0 0
TRILLIUM THERAPEUTICS INC COM NEW 89620X506 56,820 5,290,481 SH   SOLE   5,290,481 0 0
TRAVERE THERAPEUTICS INC COM 89422G107 140,192 5,614,428 SH   SOLE   5,614,428 0 0
THERAPEUTICSMD INC COM 88338N107 10,469 7,812,500 SH   SOLE   7,812,500 0 0
VERONA PHARMA PLC SPONSORED ADS 925050106 42,636 5,100,000 SH   SOLE   5,100,000 0 0
VOR BIOPHARMA INC COM 929033108 479,314 11,120,973 SH   SOLE   11,120,973 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104 5,219 312,328 SH   SOLE   312,328 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105 43,619 7,775,207 SH   SOLE   7,775,207 0 0
X4 PHARMACEUTICALS INC COM 98420X103 4,623 536,962 SH   SOLE   536,962 0 0
ZOGENIX INC COM NEW 98978L204 103,143 5,283,976 SH   SOLE   5,283,976 0 0