The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
1LIFE HEALTHCARE INC COM 68269G107 679 17,378 SH   SOLE 1 17,378 0 0
2U INC COM 90214J101 10,576 276,633 SH   SOLE 1 276,633 0 0
51JOB INC SPONSORED ADS 316827104 660 10,544 SH   SOLE 1 10,544 0 0
ACADIA HEALTHCARE COMPANY IN COM 00404A109 50,051 875,929 SH   SOLE 1 875,929 0 0
ACADIA PHARMACEUTICALS INC COM 004225108 1,571 60,879 SH   SOLE 1 60,879 0 0
ACCELERON PHARMA INC COM 00434H108 59,131 436,039 SH   SOLE 1 436,039 0 0
ACCENTURE PLC IRELAND SHS CLASS A G1151C101 104 376 SH   DFND   376 0 0
ACCENTURE PLC IRELAND SHS CLASS A G1151C101 13,424 48,595 SH   SOLE 2 48,595 0 0
ACTIVISION BLIZZARD INC COM 00507V109 76,341 820,872 SH   SOLE 1,2 820,872 0 0
ADAPTHEALTH CORP COM CL A 00653Q102 70,356 1,913,917 SH   SOLE 1 1,913,917 0 0
ADDUS HOMECARE CORP COM 006739106 30,418 290,827 SH   SOLE 1 290,827 0 0
ADOBE SYSTEMS INCORPORATED COM 00724F101 210,858 443,566 SH   SOLE 1 443,566 0 0
ADOBE SYSTEMS INCORPORATED COM 00724F101 109 230 SH   DFND   230 0 0
ADVANCED MICRO DEVICES INC COM 007903107 163,118 2,077,934 SH   SOLE 1 2,077,934 0 0
AFFILIATED MANAGERS GROUP IN COM 008252108 26,152 175,483 SH   SOLE 1 175,483 0 0
AFLAC INC COM 001055102 22,519 440,000 SH   SOLE 1 440,000 0 0
AFYA LTD CL A COM G01125106 3,746 201,527 SH   SOLE 1 201,527 0 0
AIR TRANSPORT SERVICES GRP I NOTE 1.125%10/1 00922RAB1 19,212 17,115,000 SH   SOLE 1 17,115,000 0 0
AIRBNB INC COM CL A 009066101 82,195 437,349 SH   SOLE 1 437,349 0 0
AKAMAI TECHNOLOGIES INC NOTE 0.125% 5/0 00971TAJ0 9,108 7,500,000 SH   SOLE 1 7,500,000 0 0
ALCON AG ORD SHS H01301128 19,606 282,839 SH   SOLE 2 282,839 0 0
ALEXION PHARMACEUTICALS INC COM 015351109 34,405 225,000 SH   SOLE 1 225,000 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 340,760 1,502,932 SH   SOLE 1 1,502,932 0 0
ALIGN TECHNOLOGY INC COM 016255101 77,513 143,137 SH   SOLE 1 143,137 0 0
ALLEGHANY CORP DEL COM 017175100 115,864 185,000 SH   SOLE 1 185,000 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 28,026 198,500 SH   SOLE 1 198,500 0 0
ALPHABET INC CAP STK CL A 02079K305 190 92 SH   DFND   92 0 0
ALPHABET INC CAP STK CL A 02079K305 485,616 235,448 SH   SOLE 1 235,448 0 0
ALPHABET INC CAP STK CL A 02079K305 9,694 4,700 SH Call SOLE 1 4,700 0 0
ALPHABET INC CAP STK CL C 02079K107 533,895 258,091 SH   SOLE 1,2 258,091 0 0
ALTRIA GROUP INC COM 02209S103 24,662 482,060 SH   SOLE 1 482,060 0 0
AMAZON COM INC COM 023135106 223,529 72,244 SH   SOLE 1 72,244 0 0
AMERICAN AIRLS GROUP INC NOTE 6.500% 7/0 02376RAF9 10,335 6,000,000 SH   SOLE 1 6,000,000 0 0
AMERICAN EXPRESS CO COM 025816109 6,264 44,289 SH   SOLE 1 44,289 0 0
AMERISOURCEBERGEN CORP COM 03073E105 12,576 106,510 SH   SOLE 1 106,510 0 0
AMETEK INC COM 031100100 20,855 163,275 SH   SOLE 1 163,275 0 0
AMGEN INC COM 031162100 17,023 68,419 SH   SOLE 1 68,419 0 0
AMYRIS INC COM NEW 03236M200 1,398 73,202 SH   SOLE 1 73,202 0 0
ANALOG DEVICES INC COM 032654105 192,057 1,238,441 SH   SOLE 1 1,238,441 0 0
ANSYS INC COM 03662Q105 40,786 120,114 SH   SOLE 1 120,114 0 0
ANTHEM INC COM 036752103 37,331 104,000 SH   SOLE 1 104,000 0 0
AON PLC SHS CL A G0403H108 91,469 397,500 SH   SOLE 1 397,500 0 0
APPLE INC COM 037833100 19,727 161,500 SH Call SOLE 1 161,500 0 0
APPLE INC COM 037833100 662,613 5,424,587 SH   SOLE 1 5,424,587 0 0
APPLIED MATLS INC COM 038222105 371,001 2,776,954 SH   SOLE 1 2,776,954 0 0
APTARGROUP INC COM 038336103 67,805 478,612 SH   SOLE 1 478,612 0 0
APTIV PLC SHS G6095L109 126,091 914,369 SH   SOLE 1 914,369 0 0
APTOSE BIOSCIENCES INC COM NEW 03835T200 10,957 1,833,731 SH   SOLE 1 1,833,731 0 0
ARCH CAP GROUP LTD ORD G0450A105 229,273 5,975,312 SH   SOLE 1 5,975,312 0 0
ARCO PLATFORM LTD COM CL A G04553106 3,014 118,925 SH   SOLE 1 118,925 0 0
ARCUTIS BIOTHERAPEUTICS INC COM 03969K108 45,060 1,557,543 SH   SOLE 1 1,557,543 0 0
ARENA PHARMACEUTICALS INC COM NEW 040047607 501 7,225 SH   SOLE 1 7,225 0 0
ARES CAPITAL CORP COM 04010L103 4,162 222,470 SH   SOLE 1 222,470 0 0
ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,460 22,018 SH   SOLE 1 22,018 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101 325 2,524 SH   SOLE 1 2,524 0 0
ATLASSIAN CORP PLC CL A G06242104 7,651 36,304 SH   SOLE 1 36,304 0 0
ATRICURE INC COM 04963C209 33,283 507,986 SH   SOLE 1 507,986 0 0
AUTODESK INC COM 052769106 6,230 22,477 SH   SOLE 1 22,477 0 0
AVADEL PHARMACEUTICALS PLC SPONSORED ADR 05337M104 25,264 2,794,673 SH   SOLE 1 2,794,673 0 0
AVALARA INC COM 05338G106 39,055 292,697 SH   SOLE 1 292,697 0 0
AVANTOR INC COM 05352A100 78,593 2,716,676 SH   SOLE 1 2,716,676 0 0
AXON ENTERPRISE INC COM 05464C101 14,391 101,045 SH   SOLE 1 101,045 0 0
AXONICS MODULATION TECHNOLOG COM 05465P101 43,473 725,886 SH   SOLE 1 725,886 0 0
BALLARD PWR SYS INC NEW COM 058586108 2,595 106,595 SH   SOLE 1 106,595 0 0
BANDWIDTH INC NOTE 0.250% 3/0 05988JAB9 1,534 1,000,000 SH   SOLE 1 1,000,000 0 0
BANK OF NT BUTTERFIELD&SON L SHS NEW G0772R208 5,347 139,898 SH   SOLE 1 139,898 0 0
BAXTER INTL INC COM 071813109 19,910 236,071 SH   SOLE 1 236,071 0 0
BELLUS HEALTH INC NEW COM NEW 07987C204 13,440 3,500,000 SH   SOLE 1 3,500,000 0 0
BENTLEY SYS INC COM CL B 08265T208 18,238 388,624 SH   SOLE 1 388,624 0 0
BERKLEY W R CORP COM 084423102 97,955 1,300,000 SH   SOLE 1 1,300,000 0 0
BERKSHIRE HATHAWAY INC DEL CL B NEW 084670702 71,532 280,000 SH   SOLE 1 280,000 0 0
BILIBILI INC SPONS ADS REP Z 090040106 4,310 40,254 SH   SOLE 1 40,254 0 0
BIO RAD LABS INC CL A 090572207 107,319 187,894 SH   SOLE 1 187,894 0 0
BIOGEN INC COM 09062X103 55,950 200,000 SH   SOLE 1 200,000 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 58,906 861,827 SH   SOLE 1 861,827 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 9,439 125,000 SH   SOLE 1 125,000 0 0
BIONTECH SE SPONSORED ADS 09075V102 24,568 225,000 SH   SOLE 1 225,000 0 0
BK OF AMERICA CORP COM 060505104 16,436 424,807 SH   SOLE 1 424,807 0 0
BLACK DIAMOND THERAPEUTICS I COM 09203E105 13,435 553,774 SH   SOLE 1 553,774 0 0
BLACKLINE INC COM 09239B109 23,568 217,421 SH   SOLE 1 217,421 0 0
BLACKSTONE GROUP INC COM 09260D107 7,335 98,414 SH   SOLE 1 98,414 0 0
BOOKING HOLDINGS INC COM 09857L108 13,033 5,594 SH   SOLE 1 5,594 0 0
BRIGHTCOVE INC COM 10921T101 7,074 351,566 SH   SOLE 1 351,566 0 0
BRISTOL-MYERS SQUIBB CO COM 110122108 22,022 348,843 SH   SOLE 1 348,843 0 0
BRUKER CORP COM 116794108 1,465 22,789 SH   SOLE 1 22,789 0 0
CADENCE DESIGN SYSTEM INC COM 127387108 129,378 944,436 SH   SOLE 1 944,436 0 0
CANADIAN NAT RES LTD COM 136385101 24,082 694,855 SH   SOLE 1 694,855 0 0
CANNAE HLDGS INC COM 13765N107 20,680 521,959 SH   SOLE 1 521,959 0 0
CATALENT INC COM 148806102 47,755 453,469 SH   SOLE 1 453,469 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 10,300 500,000 SH   SOLE 1 500,000 0 0
CENTENE CORP DEL COM 15135B101 41,815 654,280 SH   SOLE 1 654,280 0 0
CHANGE HEALTHCARE INC COM 15912K100 546 24,703 SH   SOLE 1 24,703 0 0
CHANGE HEALTHCARE INC UNIT 99/99/9999 15912K209 70,224 938,452 SH   SOLE 1 938,452 0 0
CHEGG INC COM 163092109 69,245 808,373 SH   SOLE 1 808,373 0 0
CHEGG INC NOTE 0.250% 5/1 163092AB5 4,448 69,438 SH   SOLE 1 69,438 0 0
CHEMED CORP NEW COM 16359R103 426 927 SH   SOLE 1 927 0 0
CHEMOCENTRYX INC COM 16383L106 36,832 718,804 SH   SOLE 1 718,804 0 0
CHUBB LIMITED COM H1467J104 182,150 1,153,069 SH   SOLE 1 1,153,069 0 0
CITIGROUP INC COM NEW 172967424 37,580 516,566 SH   SOLE 1 516,566 0 0
CITIZENS FINANCIAL GROUP INC COM 174610105 8,797 199,262 SH   SOLE 1 199,262 0 0
CLOUDFLARE INC CL A COM 18915M107 11,677 166,194 SH   SOLE 1 166,194 0 0
COGNEX CORP COM 192422103 37,558 452,559 SH   SOLE 1 452,559 0 0
COLFAX CORP COM 194014106 22,505 513,701 SH   SOLE 1 513,701 0 0
COMERICA INC COM 200340107 3,305 46,067 SH   SOLE 1 46,067 0 0
CONMED CORP COM 207410101 817 6,256 SH   SOLE 1 6,256 0 0
CONSTELLATION PHARMCETICLS I COM 210373106 5,848 250,000 SH   SOLE 1 250,000 0 0
COOPER COS INC COM NEW 216648402 40,248 104,788 SH   SOLE 1 104,788 0 0
CRITEO S A SPONS ADS 226718104 2,084 60,000 SH   SOLE 1 60,000 0 0
CROWDSTRIKE HLDGS INC CL A 22788C105 42,720 234,069 SH   SOLE 1 234,069 0 0
CSG SYS INTL INC NOTE 4.250% 3/1 126349AF6 21,000 20,000,000 SH   SOLE 1 20,000,000 0 0
CURIS INC COM NEW 231269200 16,980 1,500,000 SH   SOLE 1 1,500,000 0 0
CYBERARK SOFTWARE LTD SHS M2682V108 79,315 613,232 SH   SOLE 1 613,232 0 0
CYMABAY THERAPEUTICS INC COM 23257D103 257 56,630 SH   SOLE 1 56,630 0 0
CYTOKINETICS INC COM NEW 23282W605 62,148 2,671,884 SH   SOLE 1 2,671,884 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 17,936 400,000 SH   SOLE 1 400,000 0 0
DEXCOM INC COM 252131107 20,122 55,990 SH   SOLE 1 55,990 0 0
DICERNA PHARMACEUTICALS INC COM 253031108 27,739 1,084,813 SH   SOLE 1 1,084,813 0 0
DOCUSIGN INC COM 256163106 85,331 421,491 SH   SOLE 1 421,491 0 0
DOLBY LABORATORIES INC COM CL A 25659T107 163,333 1,654,505 SH   SOLE 1 1,654,505 0 0
DOLLAR GEN CORP NEW COM 256677105 98 483 SH   DFND   483 0 0
DOLLAR GEN CORP NEW COM 256677105 4,023 19,853 SH   SOLE 2 19,853 0 0
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201 300 30,468 SH   SOLE 1 30,468 0 0
EAST WEST BANCORP INC COM 27579R104 5,424 73,500 SH   SOLE 1 73,500 0 0
EBAY INC. COM 278642103 36,598 597,608 SH   SOLE 1 597,608 0 0
EMERSON ELEC CO COM 291011104 17,929 198,723 SH   SOLE 1 198,723 0 0
ENCOMPASS HEALTH CORP COM 29261A100 79,043 965,110 SH   SOLE 1 965,110 0 0
ENTERPRISE FINL SVCS CORP COM 293712105 5,693 115,141 SH   SOLE 1 115,141 0 0
ENVISTA HOLDINGS CORPORATION COM 29415F104 23,264 570,202 SH   SOLE 1 570,202 0 0
EPAM SYS INC COM 29414B104 4,753 11,981 SH   SOLE 1 11,981 0 0
ESSENT GROUP LTD COM G3198U102 114,570 2,412,500 SH   SOLE 1 2,412,500 0 0
ESTABLISHMENT LABS HLDGS INC COM G31249108 398 6,367 SH   SOLE 1 6,367 0 0
EURONET WORLDWIDE INC COM 298736109 1,452 10,500 SH   SOLE 2 10,500 0 0
EVERBRIDGE INC COM 29978A104 136,251 1,124,367 SH   SOLE 1 1,124,367 0 0
EVEREST RE GROUP LTD COM G3223R108 62,758 253,250 SH   SOLE 1 253,250 0 0
EXACT SCIENCES CORP NOTE 0.375% 3/0 30063PAC9 7,770 6,000,000 SH   SOLE 1 6,000,000 0 0
EXELIXIS INC COM 30161Q104 57,905 2,563,287 SH   SOLE 1 2,563,287 0 0
FACEBOOK INC CL A 30303M102 5,184 17,600 SH Call SOLE 1 17,600 0 0
FACEBOOK INC CL A 30303M102 106 361 SH   DFND   361 0 0
FACEBOOK INC CL A 30303M102 430,500 1,461,650 SH   SOLE 1 1,461,650 0 0
FIDELITY NATL INFORMATION SV COM 31620M106 76 537 SH   DFND   537 0 0
FIDELITY NATL INFORMATION SV COM 31620M106 4,994 35,514 SH   SOLE 2 35,514 0 0
FIRST AMERN FINL CORP COM 31847R102 33,990 600,000 SH   SOLE 1 600,000 0 0
FIRST REP BK SAN FRANCISCO C COM 33616C100 3,415 20,482 SH   SOLE 1 20,482 0 0
FISERV INC COM 337738108 78 652 SH   DFND   652 0 0
FISERV INC COM 337738108 27,742 233,049 SH   SOLE 1 233,049 0 0
GENERAL DYNAMICS CORP COM 369550108 2,124 11,700 SH   SOLE 2 11,700 0 0
GLOBAL BLOOD THERAPEUTICS IN COM 37890U108 30,563 750,000 SH   SOLE 1 750,000 0 0
GLOBUS MED INC CL A 379577208 43,178 700,152 SH   SOLE 1 700,152 0 0
GOLUB CAP BDC INC COM 38173M102 1,338 91,500 SH   SOLE 1 91,500 0 0
GREAT WESTN NATL BK PORTLAND COM 695263103 4,182 109,622 SH   SOLE 1 109,622 0 0
GUARDANT HEALTH INC COM 40131M109 106,011 694,468 SH   SOLE 1 694,468 0 0
HAEMONETICS CORP MASS COM 405024100 37,585 338,576 SH   SOLE 1 338,576 0 0
HDFC BANK LTD SPONSORED ADS 40415F101 383 4,933 SH   SOLE 1 4,933 0 0
HEALTHEQUITY INC COM 42226A107 386 5,681 SH   SOLE 1 5,681 0 0
HILL ROM HLDGS INC COM 431475102 17,795 161,073 SH   SOLE 1 161,073 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 133,247 1,447,709 SH   SOLE 1 1,447,709 0 0
HUBSPOT INC COM 443573100 166,423 366,402 SH   SOLE 1 366,402 0 0
ICON PLC SHS G4705A100 21,197 107,942 SH   SOLE 1 107,942 0 0
ICU MED INC COM 44930G107 457 2,223 SH   SOLE 1 2,223 0 0
INCYTE CORP COM 45337C102 61,278 754,005 SH   SOLE 1 754,005 0 0
INSMED INC COM PAR $.01 457669307 31,895 936,438 SH   SOLE 1 936,438 0 0
INSPIRE MED SYS INC COM 457730109 520 2,511 SH   SOLE 1 2,511 0 0
INTERCONTINENTAL EXCHANGE IN COM 45866F104 17,789 159,282 SH   SOLE 1 159,282 0 0
INTERSECT ENT INC COM 46071F103 268 12,856 SH   SOLE 1 12,856 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602 5,372 7,270 SH   SOLE 1 7,270 0 0
IONIS PHARMACEUTICALS INC NOTE 0.125%12/1 462222AB6 12,166 12,677,000 SH   SOLE 1 12,677,000 0 0
IQIYI INC NOTE 2.000% 4/0 46267XAD0 20,416 22,000,000 SH   SOLE 1 22,000,000 0 0
IQIYI INC NOTE 3.750%12/0 46267XAB4 101 100,000 SH   SOLE 1 100,000 0 0
IQIYI INC SPONSORED ADS 46267X108 567 34,111 SH   SOLE 1 34,111 0 0
IRHYTHM TECHNOLOGIES INC COM 450056106 224 1,615 SH   SOLE 1 1,615 0 0
ITAU UNIBANCO HLDG S A SPON ADR REP PFD 465562106 3,732 752,465 SH   SOLE 1 752,465 0 0
JAMES RIV GROUP LTD COM G5005R107 33,075 725,000 SH   SOLE 1 725,000 0 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105 20,546 125,000 SH   SOLE 1 125,000 0 0
JD.COM INC SPON ADR CL A 47215P106 65 767 SH   DFND   767 0 0
JD.COM INC SPON ADR CL A 47215P106 17,107 202,852 SH   SOLE 1 202,852 0 0
JOHNSON & JOHNSON COM 478160104 163,450 994,523 SH   SOLE 1 994,523 0 0
JPMORGAN CHASE & CO COM 46625H100 24,340 159,889 SH   SOLE 1 159,889 0 0
KALVISTA PHARMACEUTICALS INC COM 483497103 25,871 1,007,055 SH   SOLE 1 1,007,055 0 0
KULICKE & SOFFA INDS INC COM 501242101 12,323 250,930 SH   SOLE 1 250,930 0 0
KURA ONCOLOGY INC COM 50127T109 9,895 350,000 SH   SOLE 1 350,000 0 0
LABORATORY CORP AMER HLDGS COM NEW 50540R409 4,835 18,957 SH   SOLE 2 18,957 0 0
LATTICE SEMICONDUCTOR CORP COM 518415104 77,173 1,714,186 SH   SOLE 1 1,714,186 0 0
LIBERTY MEDIA CORP DEL COM SER C FRMLA 531229854 11,444 264,350 SH   SOLE 1 264,350 0 0
LITTELFUSE INC COM 537008104 23,084 87,295 SH   SOLE 1 87,295 0 0
LIVE NATION ENTERTAINMENT IN NOTE 2.500% 3/1 538034AQ2 1,402 1,000,000 SH   SOLE 1 1,000,000 0 0
LIVEPERSON INC COM 538146101 55,011 1,043,053 SH   SOLE 1 1,043,053 0 0
LIVERAMP HLDGS INC COM 53815P108 6,235 120,173 SH   SOLE 1 120,173 0 0
LUMENTUM HLDGS INC NOTE 0.500%12/1 55024UAD1 7,593 6,500,000 SH   SOLE 1 6,500,000 0 0
LYFT INC CL A COM 55087P104 9,220 145,928 SH   SOLE 1 145,928 0 0
M & T BK CORP COM 55261F104 4,077 26,891 SH   SOLE 1 26,891 0 0
MARKEL CORP COM 570535104 143,406 125,837 SH   SOLE 1 125,837 0 0
MARKETAXESS HLDGS INC COM 57060D108 7,712 15,488 SH   SOLE 1 15,488 0 0
MARSH & MCLENNAN COS INC COM 571748102 166,124 1,363,907 SH   SOLE 1 1,363,907 0 0
MASIMO CORP COM 574795100 4,553 19,824 SH   SOLE 1 19,824 0 0
MASTERCARD INCORPORATED CL A 57636Q104 104 292 SH   DFND   292 0 0
MASTERCARD INCORPORATED CL A 57636Q104 202,812 569,616 SH   SOLE 1 569,616 0 0
MATCH GROUP INC NEW COM 57667L107 68,375 497,709 SH   SOLE 1 497,709 0 0
MAXLINEAR INC COM 57776J100 3,404 99,869 SH   SOLE 1 99,869 0 0
MEDPACE HLDGS INC COM 58506Q109 1,179 7,184 SH   SOLE 1 7,184 0 0
MEDTRONIC PLC SHS G5960L103 58,770 497,500 SH   SOLE 1 497,500 0 0
MERCADOLIBRE INC COM 58733R102 9,544 6,483 SH   SOLE 1 6,483 0 0
MERIDIAN BIOSCIENCE INC COM 589584101 1,056 40,235 SH   SOLE 1 40,235 0 0
MERIT MED SYS INC COM 589889104 41,211 688,231 SH   SOLE 1 688,231 0 0
MICRON TECHNOLOGY INC COM 595112103 173,209 1,963,601 SH   SOLE 1 1,963,601 0 0
MICROSOFT CORP COM 594918104 190 806 SH   DFND   806 0 0
MICROSOFT CORP COM 594918104 784,328 3,326,665 SH   SOLE 1,2 3,326,665 0 0
MICROSOFT CORP COM 594918104 9,313 39,500 SH Call SOLE 1 39,500 0 0
MIRATI THERAPEUTICS INC COM 60468T105 6,852 40,000 SH   SOLE 1 40,000 0 0
MODIVCARE INC COM 60783X104 39,276 265,166 SH   SOLE 1 265,166 0 0
MOHAWK INDS INC COM 608190104 18,883 98,192 SH   SOLE 1 98,192 0 0
MOLINA HEALTHCARE INC COM 60855R100 64,408 275,532 SH   SOLE 1 275,532 0 0
MONOLITHIC PWR SYS INC COM 609839105 75,219 212,958 SH   SOLE 1 212,958 0 0
MORPHIC HLDG INC COM 61775R105 9,492 150,000 SH   SOLE 1 150,000 0 0
NANOSTRING TECHNOLOGIES INC COM 63009R109 32,855 500,000 SH   SOLE 1 500,000 0 0
NATERA INC COM 632307104 487 4,795 SH   SOLE 1 4,795 0 0
NETEASE INC SPONSORED ADS 64110W102 127 1,230 SH   DFND   1,230 0 0
NETEASE INC SPONSORED ADS 64110W102 11,339 109,815 SH   SOLE 1 109,815 0 0
NETFLIX INC COM 64110L106 142,099 272,398 SH   SOLE 1 272,398 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 12,527 128,817 SH   SOLE 1 128,817 0 0
NEURONETICS INC COM 64131A105 15,463 1,250,000 SH   SOLE 1 1,250,000 0 0
NEW ORIENTAL ED & TECHNOLOGY SPON ADR 647581107 560 40,000 SH   DFND   40,000 0 0
NOVAVAX INC COM NEW 670002401 16,318 90,000 SH   SOLE 1 90,000 0 0
NUTANIX INC NOTE 1/1 67059NAB4 9,904 10,100,000 SH   SOLE 1 10,100,000 0 0
NVIDIA CORPORATION COM 67066G104 253,149 474,124 SH   SOLE 1 474,124 0 0
OCULAR THERAPEUTIX INC COM 67576A100 452 27,539 SH   SOLE 1 27,539 0 0
ON SEMICONDUCTOR CORP NOTE 1.625%10/1 682189AP0 10,378 5,000,000 SH   SOLE 1 5,000,000 0 0
ONCOCYTE CORP COM 68235C107 345 66,529 SH   SOLE 1 66,529 0 0
OPTION CARE HEALTH INC COM NEW 68404L201 39,729 2,239,506 SH   SOLE 1 2,239,506 0 0
ORACLE CORP COM 68389X105 4,060 57,866 SH   SOLE 2 57,866 0 0
OREILLY AUTOMOTIVE INC COM 67103H107 2,384 4,700 SH   SOLE 2 4,700 0 0
OWENS & MINOR INC NEW COM 690732102 829 22,054 SH   SOLE 1 22,054 0 0
PAGSEGURO DIGITAL LTD COM CL A G68707101 3,389 73,192 SH   SOLE 1 73,192 0 0
PAYPAL HLDGS INC COM 70450Y103 238,504 982,146 SH   SOLE 1 982,146 0 0
PELOTON INTERACTIVE INC CL A COM 70614W100 101,730 904,747 SH   SOLE 1 904,747 0 0
PG&E CORP UNIT 99/99/9999 69331C140 91,280 800,000 SH   SOLE 1 800,000 0 0
PHOENIX NEW MEDIA LTD SPONSORED ADS 71910C103 97 54,784 SH   SOLE 1 54,784 0 0
PINDUODUO INC NOTE 12/0 722304AC6 13,293 12,500,000 SH   SOLE 1 12,500,000 0 0
PINTEREST INC CL A 72352L106 70,598 953,641 SH   SOLE 1 953,641 0 0
PNC FINL SVCS GROUP INC COM 693475105 5,136 29,282 SH   SOLE 1 29,282 0 0
POWER INTEGRATIONS INC COM 739276103 75,648 928,429 SH   SOLE 1 928,429 0 0
PPD INC COM 69355F102 12,109 320,000 SH   SOLE 1 320,000 0 0
PRICELINE GRP INC NOTE 0.900% 9/1 741503AX4 7,634 6,500,000 SH   SOLE 1 6,500,000 0 0
PROASSURANCE CORP COM 74267C106 32,112 1,200,000 SH   SOLE 1 1,200,000 0 0
PROGRESSIVE CORP COM 743315103 59,278 620,000 SH   SOLE 1 620,000 0 0
PROGYNY INC COM 74340E103 411 9,223 SH   SOLE 1 9,223 0 0
PROSPERITY BANCSHARES INC COM 743606105 5,146 68,711 SH   SOLE 1 68,711 0 0
QIAGEN NV SHS NEW N72482123 5,761 110,000 SH   SOLE 1 110,000 0 0
QORVO INC COM 74736K101 57,002 312,000 SH   SOLE 1 312,000 0 0
QUALCOMM INC COM 747525103 130,565 984,726 SH   SOLE 1 984,726 0 0
QUALTRICS INTL INC COM CL A 747601201 8,489 257,935 SH   SOLE 1 257,935 0 0
QUIDEL CORP COM 74838J101 983 7,683 SH   SOLE 1 7,683 0 0
QUOTIENT LTD SHS G73268107 34,046 9,251,653 SH   SOLE 1 9,251,653 0 0
R1 RCM INC COM 749397105 800 32,424 SH   SOLE 1 32,424 0 0
REGENERON PHARMACEUTICALS COM 75886F107 35,486 75,000 SH   SOLE 1 75,000 0 0
REINSURANCE GRP OF AMERICA I COM NEW 759351604 72,479 575,000 SH   SOLE 1 575,000 0 0
RENAISSANCERE HLDGS LTD COM G7496G103 114,293 713,217 SH   SOLE 1,2 713,217 0 0
REVANCE THERAPEUTICS INC COM 761330109 32,275 1,154,734 SH   SOLE 1 1,154,734 0 0
RINGCENTRAL INC CL A 76680R206 9,383 31,498 SH   SOLE 1 31,498 0 0
RINGCENTRAL INC NOTE 3/0 76680RAF4 6,604 6,000,000 SH   SOLE 1 6,000,000 0 0
RLI CORP COM 749607107 30,682 275,000 SH   SOLE 1 275,000 0 0
ROBLOX CORP CL A 771049103 12,772 197,003 SH   SOLE 1 197,003 0 0
ROCKWELL AUTOMATION INC COM 773903109 15,444 58,183 SH   SOLE 1 58,183 0 0
S&P GLOBAL INC COM 78409V104 14,147 40,092 SH   SOLE 1 40,092 0 0
SABRE CORP COM 78573M104 10,290 694,814 SH   SOLE 1 694,814 0 0
SALESFORCE COM INC COM 79466L302 92,927 438,606 SH   SOLE 1 438,606 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103 7,599 150,000 SH   SOLE 1 150,000 0 0
SEA LTD SPONSORD ADS 81141R100 17,413 78,003 SH   SOLE 1 78,003 0 0
SEAGEN INC COM 81181C104 8,332 60,000 SH   SOLE 1 60,000 0 0
SEASPINE HLDGS CORP COM 81255T108 346 19,901 SH   SOLE 1 19,901 0 0
SENSATA TECHNOLOGIES HLDG PL SHS G8060N102 18,031 311,144 SH   SOLE 2 311,144 0 0
SERVICENOW INC COM 81762P102 149,102 298,139 SH   SOLE 1 298,139 0 0
SHIFT TECHNOLOGIES INC CL A 82452T107 8,218 987,787 SH   SOLE 1 987,787 0 0
SHOPIFY INC CL A 82509L107 5,593 5,055 SH   SOLE 1 5,055 0 0
SIGNATURE BK NEW YORK N Y COM 82669G104 6,179 27,329 SH   SOLE 1 27,329 0 0
SILK RD MED INC COM 82710M100 246 4,854 SH   SOLE 1 4,854 0 0
SLR INVESTMENT CORP COM 83413U100 4,114 231,645 SH   SOLE 1 231,645 0 0
SMARTSHEET INC COM CL A 83200N103 54,998 860,413 SH   SOLE 1 860,413 0 0
SNAP INC CL A 83304A106 163,719 3,130,973 SH   SOLE 1 3,130,973 0 0
SNOWFLAKE INC CL A 833445109 42,451 185,149 SH   SOLE 1 185,149 0 0
SOLAREDGE TECHNOLOGIES INC COM 83417M104 54,896 190,982 SH   SOLE 1 190,982 0 0
SOUTHWEST AIRLS CO NOTE 1.250% 5/0 844741BG2 6,888 4,000,000 SH   SOLE 1 4,000,000 0 0
SPOTIFY TECHNOLOGY S A SHS L8681T102 156,808 585,215 SH   SOLE 1 585,215 0 0
SQUARE INC CL A 852234103 3,728 16,418 SH   SOLE 1 16,418 0 0
SS&C TECHNOLOGIES HLDGS INC COM 78467J100 23,739 339,766 SH   SOLE 1 339,766 0 0
SSR MNG INC NOTE 2.500% 4/0 784730AB9 19,786 16,839,000 SH   SOLE 1 16,839,000 0 0
STERIS PLC SHS USD G8473T100 58,121 305,128 SH   SOLE 1 305,128 0 0
STITCH FIX INC COM CL A 860897107 3,253 65,674 SH   SOLE 1 65,674 0 0
STONECO LTD COM CL A G85158106 10,097 164,936 SH   SOLE 1 164,936 0 0
SUMMIT THERAPEUTICS INC COM 86627T108 36,152 6,158,800 SH   SOLE 1 6,158,800 0 0
SUPERNUS PHARMACEUTICALS INC NOTE 0.625% 4/0 868459AD0 13,036 13,453,000 SH   SOLE 1 13,453,000 0 0
SURGERY PARTNERS INC COM 86881A100 32,700 738,826 SH   SOLE 1 738,826 0 0
SVB FINANCIAL GROUP COM 78486Q101 4,207 8,523 SH   SOLE 1 8,523 0 0
SYNEOS HEALTH INC CL A 87166B102 71,267 939,578 SH   SOLE 1 939,578 0 0
TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADS 874039100 11,243 95,052 SH   SOLE 1,2 95,052 0 0
TAKE-TWO INTERACTIVE SOFTWAR COM 874054109 19,183 108,561 SH   SOLE 1 108,561 0 0
TANDEM DIABETES CARE INC COM NEW 875372203 1,434 16,244 SH   SOLE 1 16,244 0 0
TAYLOR MORRISON HOME CORP COM 87724P106 21,689 703,955 SH   SOLE 1 703,955 0 0
TE CONNECTIVITY LTD REG SHS H84989104 171,805 1,330,687 SH   SOLE 1 1,330,687 0 0
TELEFLEX INCORPORATED COM 879369106 50,089 120,563 SH   SOLE 1 120,563 0 0
TENABLE HLDGS INC COM 88025T102 87,532 2,419,001 SH   SOLE 1 2,419,001 0 0
TENET HEALTHCARE CORP COM NEW 88033G407 643 12,370 SH   SOLE 1 12,370 0 0
T-MOBILE US INC COM 872590104 38,695 308,842 SH   SOLE 1 308,842 0 0
TORONTO DOMINION BK ONT COM NEW 891160509 8,989 122,936 SH   SOLE 1 122,936 0 0
TRAVELERS COMPANIES INC COM 89417E109 111,890 743,950 SH   SOLE 1 743,950 0 0
TREVENA INC COM 89532E109 191 106,900 SH   SOLE 1 106,900 0 0
TRIPADVISOR INC COM 896945201 180,279 3,351,540 SH   SOLE 1 3,351,540 0 0
TWILIO INC CL A 90138F102 57,808 169,645 SH   SOLE 1 169,645 0 0
TWITTER INC COM 90184L102 97,422 1,531,075 SH   SOLE 1 1,531,075 0 0
UBER TECHNOLOGIES INC COM 90353T100 148,027 2,715,598 SH   SOLE 1 2,715,598 0 0
UBS GROUP AG SHS H42097107 7,821 510,218 SH   SOLE 1 510,218 0 0
UNIQURE NV SHS N90064101 742 22,031 SH   SOLE 1 22,031 0 0
UNITED RENTALS INC COM 911363109 25,620 77,800 SH   SOLE 1 77,800 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102 1,417 8,474 SH   SOLE 1 8,474 0 0
UNITEDHEALTH GROUP INC COM 91324P102 52,224 140,360 SH   SOLE 1 140,360 0 0
UNITEDHEALTH GROUP INC COM 91324P102 117 315 SH   DFND   315 0 0
UNITY SOFTWARE INC COM 91332U101 18,368 183,109 SH   SOLE 1 183,109 0 0
UNUM THERAPEUTICS INC COM 19240Q201 8,780 1,000,000 SH   SOLE 1 1,000,000 0 0
US BANCORP DEL COM NEW 902973304 7,085 128,095 SH   SOLE 1 128,095 0 0
US FOODS HLDG CORP COM 912008109 35,782 938,673 SH   SOLE 1 938,673 0 0
VEECO INSTRS INC DEL COM 922417100 14,965 721,575 SH   SOLE 1 721,575 0 0
VERONA PHARMA PLC SPONSORED ADS 925050106 8,360 1,000,000 SH   SOLE 1 1,000,000 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 69,839 325,000 SH   SOLE 1 325,000 0 0
VISA INC COM CL A 92826C839 97 460 SH   DFND   460 0 0
VISA INC COM CL A 92826C839 223,105 1,053,725 SH   SOLE 1 1,053,725 0 0
WEBSTER FINL CORP CONN COM 947890109 4,612 83,679 SH   SOLE 1 83,679 0 0
WELLS FARGO CO NEW COM 949746101 29,325 750,577 SH   SOLE 1 750,577 0 0
WORKDAY INC CL A 98138H101 98,159 395,117 SH   SOLE 1 395,117 0 0
Y-MABS THERAPEUTICS INC COM 984241109 243 8,029 SH   SOLE 1 8,029 0 0
ZAI LAB LTD ADR 98887Q104 17,236 129,173 SH   SOLE 1 129,173 0 0
ZENDESK INC COM 98936J101 186,080 1,403,104 SH   SOLE 1 1,403,104 0 0
ZENTALIS PHARMACEUTICALS INC COM 98943L107 19,526 450,000 SH   SOLE 1 450,000 0 0
ZILLOW GROUP INC CL C CAP STK 98954M200 92,613 714,385 SH   SOLE 1 714,385 0 0
ZILLOW GROUP INC NOTE 1.500% 7/0 98954MAC5 1,679 1,000,000 SH   SOLE 1 1,000,000 0 0
ZIMMER BIOMET HOLDINGS INC COM 98956P102 77,800 486,009 SH   SOLE 1 486,009 0 0
ZOOM VIDEO COMMUNICATIONS IN CL A 98980L101 107,152 333,505 SH   SOLE 1 333,505 0 0
ZUORA INC COM CL A 98983V106 17,934 1,211,753 SH   SOLE 1 1,211,753 0 0