The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
4D MOLECULAR THERAPEUTICS IN COM 35104E100 3,735 86,100 SH   SOLE   86,100 0 0
ADVERUM BIOTECHNOLOGIES INC COM 00773U108 986 99,992 SH   SOLE   99,992 0 0
ALEXION PHARMACEUTICALS INC COM 015351109 3,871 25,318 SH   SOLE   25,318 0 0
ALPINE IMMUNE SCIENCES INC COM 02083G100 3,318 313,064 SH   SOLE   313,064 0 0
ARYA SCIENCES ACQU CORP IV CL A G31659108 3,142 300,000 SH   SOLE   300,000 0 0
ASSEMBLY BIOSCIENCES INC COM 045396108 5,161 1,122,000 SH   SOLE   1,122,000 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108 12,850 258,446 SH   SOLE   258,446 0 0
AVIDITY BIOSCIENCES INC COM 05370A108 2,380 109,130 SH   SOLE   109,130 0 0
BIOATLA INC COM 09077B104 161,639 3,179,362 SH   SOLE   3,179,362 0 0
BRIDGEBIO PHARMA INC NOTE 2.500% 3/1 10806XAB8 3,216 1,950,000 PRN   SOLE   1,950,000 0 0
C4 THERAPEUTICS INC COM STK 12529R107 17,166 464,068 SH   SOLE   464,068 0 0
CARDIFF ONCOLOGY INC COM 14147L108 395 42,684 SH   SOLE   42,684 0 0
CATABASIS PHARMACEUTICALS IN COM NEW 14875P206 2,240 775,000 SH   SOLE   775,000 0 0
COMPASS PATHWAYS PLC SPONSORED ADS 20451W101 1,574 42,743 SH   SOLE   42,743 0 0
CUTERA INC COM 232109108 3,606 120,000 SH   SOLE   120,000 0 0
DARIOHEALTH CORP COM NEW 23725P209 3,444 178,814 SH   SOLE   178,814 0 0
DEERFIELD HEALTHCARE TECH AC COM CL A 244413100 1,441 118,900 SH   SOLE   118,900 0 0
DEXCOM INC COM 252131107 2,492 6,935 SH   SOLE   6,935 0 0
DYNE THERAPEUTICS INC COM 26818M108 2,708 174,360 SH   SOLE   174,360 0 0
EDAP TMS S A SPONSORED ADR 268311107 2,096 249,566 SH   SOLE   249,566 0 0
EDGEWISE THERAPEUTICS INC COM 28036F105 3,250 100,000 SH   SOLE   100,000 0 0
EIGER BIOPHARMACEUTICALS INC COM 28249U105 1,890 213,519 SH   SOLE   213,519 0 0
ESSA PHARMA INC COM NEW 29668H708 60,135 2,070,052 SH   SOLE   2,070,052 0 0
ESTABLISHMENT LABS HLDGS INC COM G31249108 3,824 61,151 SH   SOLE   61,151 0 0
EXELIXIS INC COM 30161Q104 4,119 182,347 SH   SOLE   182,347 0 0
FLEXION THERAPEUTICS INC COM 33938J106 4,676 522,500 SH   SOLE   522,500 0 0
GALECTO INC COM 36322Q107 9,189 1,512,648 SH   SOLE   1,512,648 0 0
GOSSAMER BIO INC NOTE 5.000% 6/0 38341PAA0 3,328 3,750,000 PRN   SOLE   3,750,000 0 0
HIMS & HERS HEALTH INC *W EXP 01/20/202 433000114 404 91,793 SH   SOLE   91,793 0 0
INARI MED INC COM 45332Y109 2,295 21,450 SH   SOLE   21,450 0 0
INHIBRX INC COM 45720L107 8,058 401,493 SH   SOLE   401,493 0 0
IRADIMED CORP COM 46266A109 12,423 482,070 SH   SOLE   482,070 0 0
ITAMAR MED LTD SPONSORED ADS 465437101 6,468 270,080 SH   SOLE   270,080 0 0
IVERIC BIO INC COM 46583P102 20,894 3,380,979 SH   SOLE   3,380,979 0 0
KADMON HLDGS INC COM 48283N106 1,309 336,442 SH   SOLE   336,442 0 0
KINNATE BIOPHARMA INC COM 49705R105 3,396 109,000 SH   SOLE   109,000 0 0
KONINKLIJKE PHILIPS N V NY REG SH NEW 500472303 3,482 61,050 SH   SOLE   61,050 0 0
KRYSTAL BIOTECH INC COM 501147102 12,854 166,844 SH   SOLE   166,844 0 0
KYMERA THERAPEUTICS INC COM 501575104 1,093 28,116 SH   SOLE   28,116 0 0
LANTHEUS HLDGS INC COM 516544103 20,673 967,372 SH   SOLE   967,372 0 0
LYRA THERAPEUTICS INC COM 55234L105 5,515 475,814 SH   SOLE   475,814 0 0
MAGENTA THERAPEUTICS INC COM 55910K108 1,184 100,000 SH   SOLE   100,000 0 0
MERCK & CO. INC COM 58933Y105 2,321 30,106 SH   SOLE   30,106 0 0
MIMEDX GROUP INC COM 602496101 5,150 500,000 SH   SOLE   500,000 0 0
MIRATI THERAPEUTICS INC COM 60468T105 594 3,466 SH   SOLE   3,466 0 0
MISONIX INC COM 604871103 5,903 301,333 SH   SOLE   301,333 0 0
MORPHIC HLDG INC COM 61775R105 1,361 21,500 SH   SOLE   21,500 0 0
NATERA INC COM 632307104 7,944 78,239 SH   SOLE   78,239 0 0
NEOGENOMICS INC COM NEW 64049M209 2,216 45,951 SH   SOLE   45,951 0 0
NOVOCURE LTD ORD SHS G6674U108 3,347 25,325 SH   SOLE   25,325 0 0
OAK STR HEALTH INC COM 67181A107 1,499 27,612 SH   SOLE   27,612 0 0
ONCOCYTE CORP COM 68235C107 1,541 297,000 SH   SOLE   297,000 0 0
ONCORUS INC COM 68236R103 929 66,722 SH   SOLE   66,722 0 0
PIERIS PHARMACEUTICALS INC COM 720795103 1,285 500,000 SH   SOLE   500,000 0 0
RAFAEL HLDGS INC COM CL B 75062E106 3,419 85,637 SH   SOLE   85,637 0 0
RENALYTIX AI PLC ADS 75973T101 2,053 80,000 SH   SOLE   80,000 0 0
REPARE THERAPEUTICS INC COM 760273102 4,092 133,324 SH   SOLE   133,324 0 0
REVANCE THERAPEUTICS INC COM 761330109 870 31,136 SH   SOLE   31,136 0 0
REVOLUTION MEDICINES INC COM 76155X100 2,624 57,200 SH   SOLE   57,200 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103 1,322 26,101 SH   SOLE   26,101 0 0
SIENTRA INC COM 82621J105 2,755 377,900 SH   SOLE   377,900 0 0
SILVERBACK THERAPEUTICS INC COM 82835W108 4,243 97,256 SH   SOLE   97,256 0 0
STAAR SURGICAL CO COM PAR $0.01 852312305 1,760 16,700 SH   SOLE   16,700 0 0
SURMODICS INC COM 868873100 8,650 154,275 SH   SOLE   154,275 0 0
TCR2 THERAPEUTICS INC COM 87808K106 3,138 142,137 SH   SOLE   142,137 0 0
THERATECHNOLOGIES INC COM 88338H100 26,867 6,951,347 SH   SOLE   6,951,347 0 0
TRILLIUM THERAPEUTICS INC COM NEW 89620X506 1,115 103,819 SH   SOLE   103,819 0 0
TURNING POINT THERAPEUTICS I COM 90041T108 528 5,577 SH   SOLE   5,577 0 0
VAXCYTE INC COM 92243G108 5,800 293,650 SH   SOLE   293,650 0 0
VESPER HEALTHCARE ACQSTN COR COM CL A 92538T104 9,944 920,716 SH   SOLE   920,716 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104 1,131 67,685 SH   SOLE   67,685 0 0
XENON PHARMACEUTICALS INC COM 98420N105 12,675 708,117 SH   SOLE   708,117 0 0