The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
10X GENOMICS INC CL A COM 88025U109 141,476 781,635 SH   DFND   0 0 781,635
1LIFE HEALTHCARE INC COM 68269G107 228,828 5,855,370 SH   DFND   0 0 5,855,370
2U INC COM 90214J101 3,334 87,197 SH   DFND   0 0 87,197
89BIO INC COM 282559103 732 30,916 SH   DFND   0 0 30,916
ABIOMED INC COM 003654100 57,483 180,351 SH   DFND   0 0 180,351
ACCEL ENTERTAINMENT INC COM CL A1 00436Q106 26 2,400 SH   DFND   0 0 2,400
ACCOLADE INC COM 00437E102 86,074 1,897,161 SH   DFND   0 0 1,897,161
ACTIVISION BLIZZARD INC COM 00507V109 2,056 22,111 SH   DFND   0 0 22,111
ADAPTIVE BIOTECHNOLOGIES COR COM 00650F109 95,988 2,384,205 SH   DFND   0 0 2,384,205
ADOBE SYSTEMS INCORPORATED COM 00724F101 55,368 116,473 SH   DFND   0 0 116,473
ADYEN NV 144A COMMONSTOCK N3501V104 70,905 31,694 SH   DFND   0 0 31,694
AFFIRM HLDGS INC COM CL A 00827B106 175,374 2,479,834 SH   DFND   0 0 2,479,834
AFYA LTD CL A COM G01125106 4,162 223,895 SH   DFND   0 0 223,895
AGORA INC ADS 00851L103 69,338 1,379,315 SH   DFND   0 0 1,379,315
AIRBNB INC COM CL A 009066101 54,425 289,585 SH   DFND   0 0 289,585
ALAMOS GOLD INC NEW COM CL A 011532108 4,042 517,544 SH   DFND   0 0 517,544
ALECTOR INC COM 014442107 36,910 1,832,690 SH   DFND   0 0 1,832,690
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 8 34 SH   DFND   0 0 34
ALLAKOS INC COM 01671P100 10,440 90,957 SH   DFND   0 0 90,957
ALLOGENE THERAPEUTICS INC COM 019770106 1 29 SH   DFND   0 0 29
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 131,256 929,643 SH   DFND   0 0 929,643
ALPHABET INC CAP STK CL A 02079K305 80,494 39,027 SH   DFND   0 0 39,027
ALPHABET INC CAP STK CL C 02079K107 112,164 54,221 SH   DFND   0 0 54,221
ALTERYX INC COM CL A 02156B103 2 30 SH   DFND   0 0 30
ALTIMETER GROWTH CORP CL A G0370L108 390 33,315 SH   DFND   0 0 33,315
AMAZON COM INC COM 023135106 466,732 150,847 SH   DFND   0 0 150,847
AMBARELLA INC SHS G037AX101 33,855 337,239 SH   DFND   0 0 337,239
AMERICAN EXPRESS CO COM 025816109 151 1,070 SH   DFND   0 0 1,070
AMERICAN TOWER CORP NEW COM 03027X100 18,270 76,423 SH   DFND   0 0 76,423
AMERICAN WELL CORP CL A 03044L105 0 13 SH   DFND   0 0 13
AMICUS THERAPEUTICS INC COM 03152W109 22,778 2,305,432 SH   DFND   0 0 2,305,432
ANAPLAN INC COM 03272L108 2 41 SH   DFND   0 0 41
ANTERIX INC COM 03676C100 303 6,430 SH   DFND   0 0 6,430
APA CORPORATION COM 03743Q108 2,751 153,685 SH   DFND   0 0 153,685
APPFOLIO INC COM CL A 03783C100 57,419 406,045 SH   DFND   0 0 406,045
APPLE INC COM 037833100 20,802 170,296 SH   DFND   0 0 170,296
APPLIED MATLS INC COM 038222105 22 168 SH   DFND   0 0 168
APPLIED OPTOELECTRONICS INC COM 03823U102 59 7,003 SH   DFND   0 0 7,003
ARCTOS NORTHSTAR ACQUIS CORP UNIT 99/99/9999 G0477L118 4,223 422,696 SH   DFND   0 0 422,696
ARCUS BIOSCIENCES INC COM 03969F109 8,542 304,212 SH   DFND   0 0 304,212
ARENA PHARMACEUTICALS INC COM NEW 040047607 43,305 624,078 SH   DFND   0 0 624,078
ARGENX SE SPONSORED ADR 04016X101 36,531 132,652 SH   DFND   0 0 132,652
ARISTA NETWORKS INC COM 040413106 9,010 29,846 SH   DFND   0 0 29,846
ARITZIA INC SUB VTG SHS ISIN CA04045U1021 SEDOL BDCG2C2 COMMONSTOCK 04045U102 17,148 738,092 SH   DFND   0 0 738,092
ARVINAS INC COM 04335A105 105,002 1,588,528 SH   DFND   0 0 1,588,528
ASANA INC CL A 04342Y104 84,513 2,957,059 SH   DFND   0 0 2,957,059
ASHTEAD GROUP ORD GBP010 ISIN GB0000536739 SEDOL 0053673 COMMONSTOCK G05320109 5 85 SH   DFND   0 0 85
ATLASSIAN CORP PLC CL A G06242104 42,713 202,662 SH   DFND   0 0 202,662
ATRICURE INC COM 04963C209 3 42 SH   DFND   0 0 42
AURINIA PHARMACEUTICALS INC COM 05156V102 2,400 184,825 SH   DFND   0 0 184,825
AUSTERLITZ ACQUISITION CORP UNIT 99/99/9999 G0633D117 7,020 699,238 SH   DFND   0 0 699,238
AUSTERLITZ ACQUISITION CORP UNIT 99/99/9999 G0633U119 8,521 849,533 SH   DFND   0 0 849,533
AUTODESK INC COM 052769106 106,132 382,940 SH   DFND   0 0 382,940
AVID TECHNOLOGY INC COM 05367P100 44,440 2,105,174 SH   DFND   0 0 2,105,174
AVIDITY BIOSCIENCES INC COM 05370A108 287 13,156 SH   DFND   0 0 13,156
AXIS BANK LIMITED GDR REG S ISIN US05462W1099 SEDOL B06CDW2 COMMONSTOCK 05462W109 3,076 64,359 SH   DFND   0 0 64,359
AYR WELLNESS INC SUB LTD VTG SHS ISIN CA05475P1099 SEDOL BNNQQ COMMONSTOCK 05475P109 13,747 459,828 SH   DFND   0 0 459,828
AZEK CO INC CL A 05478C105 64,427 1,532,149 SH   DFND   0 0 1,532,149
AZUL S A SPONSR ADR PFD 05501U106 24,568 1,216,826 SH   DFND   0 0 1,216,826
BAMBUSER AB NPV ISIN SE0009663834 SEDOL BD8Z3Y2 COMMONSTOCK W1R91S102 24,942 7,820,119 SH   DFND   0 0 7,820,119
BARCLAYS BANK PLC IPTH SR B S&P 06746P621 404 35,397 SH   DFND   0 0 35,397
BASICFIT NV 144A REG S ISIN NL0011872650 SEDOL BD9Y9B7 COMMONSTOCK N10058100 20 510 SH   DFND   0 0 510
BEACON ROOFING SUPPLY INC COM 073685109 12,994 248,360 SH   DFND   0 0 248,360
BEAM THERAPEUTICS INC COM 07373V105 11,518 143,900 SH   DFND   0 0 143,900
BERKLEY W R CORP COM 084423102 6,147 81,574 SH   DFND   0 0 81,574
BERKSHIRE HATHAWAY INC DEL CL B NEW 084670702 1,125 4,405 SH   DFND   0 0 4,405
BEYOND MEAT INC COM 08862E109 89,323 686,470 SH   DFND   0 0 686,470
BIOCRYST PHARMACEUTICALS INC COM 09058V103 2,150 211,407 SH   DFND   0 0 211,407
BIOGEN INC COM 09062X103 1,798 6,428 SH   DFND   0 0 6,428
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 18,005 263,420 SH   DFND   0 0 263,420
BIONANO GENOMICS INC COM 09075F107 111 13,707 SH   DFND   0 0 13,707
BK OF AMERICA CORP COM 060505104 4 91 SH   DFND   0 0 91
BOSTON SCIENTIFIC CORP COM 101137107 802 20,748 SH   DFND   0 0 20,748
BRIDGEBIO PHARMA INC COM 10806X102 47,110 764,767 SH   DFND   0 0 764,767
BRP GROUP INC COM CL A 05589G102 12,270 450,268 SH   DFND   0 0 450,268
BUMBLE INC COM CL A 12047B105 16,169 259,198 SH   DFND   0 0 259,198
BURNING ROCK BIOTECH LTD SPONSORED ADS 12233L107 18,525 688,132 SH   DFND   0 0 688,132
BUTTERFLY NETWORK INC COM CL A 124155102 838 49,792 SH   DFND   0 0 49,792
CALIX INC COM 13100M509 119,607 3,450,861 SH   DFND   0 0 3,450,861
CAPITOL INVESTMENT CORP V COM CL A 14064F100 9,460 936,653 SH   DFND   0 0 936,653
CAPITOL INVESTMENT CORP V UNIT 99/99/9999 14064F209 256 24,436 SH   DFND   0 0 24,436
CARL ZEISS MEDITEC AG NPV ISIN DE0005313704 SEDOL 5922961 COMMONSTOCK D14895102 1,765 11,687 SH   DFND   0 0 11,687
CARVANA CO CL A 146869102 364,829 1,390,353 SH   DFND   0 0 1,390,353
CATAPULT GROUP INTERNATIONAL ISIN AU000000CAT9 SEDOL BTL0Y76 COMMONSTOCK Q2159P101 236 164,000 SH   DFND   0 0 164,000
CELLNEX TELECOM SAU EUR025 144A REG S ISIN ES0105066007 SEDOL COMMONSTOCK E2R41M104 4,852 84,087 SH   DFND   0 0 84,087
CELSIUS HLDGS INC COM NEW 15118V207 19,260 400,827 SH   DFND   0 0 400,827
CHARLES RIV LABS INTL INC COM 159864107 7,347 25,351 SH   DFND   0 0 25,351
CHART INDS INC COM 16115Q308 86 607 SH   DFND   0 0 607
CHEGG INC COM 163092109 144,900 1,691,575 SH   DFND   0 0 1,691,575
CHEVRON CORP NEW COM 166764100 96 920 SH   DFND   0 0 920
CHEWY INC CL A 16679L109 38,423 453,581 SH   DFND   0 0 453,581
CHIPOTLE MEXICAN GRILL INC COM 169656105 34 24 SH   DFND   0 0 24
CHUBB LIMITED COM H1467J104 19,363 122,573 SH   DFND   0 0 122,573
CITIGROUP INC COM NEW 172967424 148 2,035 SH   DFND   0 0 2,035
CLASS ACCELERATION CORP COM 18274B106 2,738 283,415 SH   DFND   0 0 283,415
CLASS ACCELERATION CORP UNIT 99/99/9999 18274B205 5,321 537,521 SH   DFND   0 0 537,521
CLASS ACCELERATION CORP UNIT UNIT SPLIT FROM CUSIP 18274B205 COMMONSTOCK 182NUS923 5,842 590,106 SH   DFND   0 0 590,106
CLEARFIELD INC COM 18482P103 1,401 46,496 SH   DFND   0 0 46,496
CLOUDFLARE INC CL A COM 18915M107 346,076 4,925,653 SH   DFND   0 0 4,925,653
CM LIFE SCIENCES II INC UNIT 02/25/2028 125842203 954 74,570 SH   DFND   0 0 74,570
CODEXIS INC COM 192005106 56,236 2,456,793 SH   DFND   0 0 2,456,793
COMMSCOPE HLDG CO INC COM 20337X109 176 11,447 SH   DFND   0 0 11,447
CONSOLIDATED COMM HLDGS INC COM 209034107 14 2,000 SH   DFND   0 0 2,000
CONTROLADORA VUELA COMP DE A SPON ADR RP 10 21240E105 70,299 4,929,829 SH   DFND   0 0 4,929,829
CORECIVIC INC COM 21871N101 73 8,079 SH   DFND   0 0 8,079
COUPA SOFTWARE INC COM 22266L106 20,470 80,440 SH   DFND   0 0 80,440
COUPANG INC CL A 22266T109 27,249 552,163 SH   DFND   0 0 552,163
COVETRUS INC COM 22304C100 0 8 SH   DFND   0 0 8
CREE INC COM 225447101 1,623 15,007 SH   DFND   0 0 15,007
CROWDSTRIKE HLDGS INC CL A 22788C105 44,238 242,386 SH   DFND   0 0 242,386
CVS HEALTH CORP COM 126650100 134 1,775 SH   DFND   0 0 1,775
D R HORTON INC COM 23331A109 4,464 50,095 SH   DFND   0 0 50,095
DATADOG INC CL A COM 23804L103 4,209 50,507 SH   DFND   0 0 50,507
DECARBONIZATION PLUS ACQU II UNIT 03/19/2026 24279D204 6,176 620,097 SH   DFND   0 0 620,097
DEERE & CO COM 244199105 49,746 132,961 SH   DFND   0 0 132,961
DELTA AIR LINES INC DEL COM NEW 247361702 513 10,632 SH   DFND   0 0 10,632
DENALI THERAPEUTICS INC COM 24823R105 171,560 3,004,553 SH   DFND   0 0 3,004,553
DENBURY INC COM 24790A101 16,641 347,479 SH   DFND   0 0 347,479
DERMTECH INC COM 24984K105 2,837 55,863 SH   DFND   0 0 55,863
DEXCOM INC COM 252131107 84,914 236,272 SH   DFND   0 0 236,272
DISH NETWORK CORPORATION CL A 25470M109 32,915 909,264 SH   DFND   0 0 909,264
DISNEY WALT CO COM 254687106 17,576 95,250 SH   DFND   0 0 95,250
DIVERSIFIED GAS OIL PLC ORD GBP001 ISIN GB00BYX7JT74 SEDOL B COMMONSTOCK G2891G105 11,067 7,226,216 SH   DFND   0 0 7,226,216
DOCUSIGN INC COM 256163106 280,444 1,385,250 SH   DFND   0 0 1,385,250
DOWNEY FINL CORP COMMONSTOCK 261018105 0 200 SH   DFND   0 0 200
DRAFTKINGS INC COM CL A 26142R104 1,973 32,167 SH   DFND   0 0 32,167
DRAGONEER GROWTH OPPORTUN CO COM CL A G28302100 906 89,230 SH   DFND   0 0 89,230
DRIVE SHACK INC COM 262077100 4 1,250 SH   DFND   0 0 1,250
DUCK CREEK TECHNOLOGIES INC SHS 264120106 5,607 124,204 SH   DFND   0 0 124,204
EARGO INC COM 270087109 25,004 500,588 SH   DFND   0 0 500,588
ELASTIC N V ORD SHS N14506104 4 38 SH   DFND   0 0 38
ENDEAVOUR MINING CORPORATION COM USD010 ISIN KYG3040R1589 SEDO COMMONSTOCK G3040R158 6,814 338,101 SH   DFND   0 0 338,101
ENPHASE ENERGY INC COM 29355A107 235,049 1,449,490 SH   DFND   0 0 1,449,490
EPAM SYS INC COM 29414B104 138,217 348,425 SH   DFND   0 0 348,425
EQUATOR EXPLORATION COM STK NPV COMMONSTOCK G3084F128 0 215,000 SH   DFND   0 0 215,000
ESPERION THERAPEUTICS INC NE COM 29664W105 28 1,006 SH   DFND   0 0 1,006
ETSY INC COM 29786A106 69,356 343,909 SH   DFND   0 0 343,909
EVENTBRITE INC COM CL A 29975E109 2,471 111,506 SH   DFND   0 0 111,506
EVEREST RE GROUP LTD COM G3223R108 4,669 18,841 SH   DFND   0 0 18,841
EVERI HLDGS INC COM 30034T103 26,850 1,902,887 SH   DFND   0 0 1,902,887
EXACT SCIENCES CORP COM 30063P105 193,559 1,468,801 SH   DFND   0 0 1,468,801
FACEBOOK INC CL A 30303M102 30,876 104,832 SH   DFND   0 0 104,832
FARFETCH LTD ORD SH CL A 30744W107 5,729 108,060 SH   DFND   0 0 108,060
FASTLY INC CL A 31188V100 1,039 15,436 SH   DFND   0 0 15,436
FATHOM HOLDINGS INC COM 31189V109 15,730 429,416 SH   DFND   0 0 429,416
FERGUSON PLC ORD GBP010 ISIN JE00BJVNSS43 SEDOL BJVNSS4 COMMONSTOCK ZZDKWOTT6 12,800 107,030 SH   DFND   0 0 107,030
FG NEW AMER ACQUISITION CORP COM 30259V106 14,975 1,469,569 SH   DFND   0 0 1,469,569
FIVERR INTL LTD ORD SHS M4R82T106 926 4,264 SH   DFND   0 0 4,264
FLOOR & DECOR HLDGS INC CL A 339750101 112,022 1,173,252 SH   DFND   0 0 1,173,252
FLUIDRA SA EUR1 ISIN ES0137650018 SEDOL B28V440 COMMONSTOCK E52619108 22,233 776,862 SH   DFND   0 0 776,862
FLUTTER ENTERTAINMENT PLC ORD EUR009 CDI ISIN IE00BWT6H894 S COMMONSTOCK G3643J108 512 2,393 SH   DFND   0 0 2,393
FOREST ROAD ACQUISITION COR UNIT 99/99/9999 34619V202 7,485 751,549 SH   DFND   0 0 751,549
FRANCO NEV CORP COM 351858105 8,993 71,781 SH   DFND   0 0 71,781
FRESHPET INC COM 358039105 291,216 1,833,738 SH   DFND   0 0 1,833,738
FRIENDLY ENERGY EXPLORATION COM NPV COMMONSTOCK 35846A200 0 690 SH   DFND   0 0 690
GALAPAGOS NV NPV ISIN BE0003818359 SEDOL B07Q2V5 COMMONSTOCK B44170106 21,498 276,637 SH   DFND   0 0 276,637
GANNETT CO INC COM 36472T109 3 541 SH   DFND   0 0 541
GENERAL ELECTRIC CO COM 369604103 13 1,000 SH   DFND   0 0 1,000
GEOPARK LTD USD SHS G38327105 5,946 371,617 SH   DFND   0 0 371,617
GLAUKOS CORP COM 377322102 70,869 844,379 SH   DFND   0 0 844,379
GLOBANT S A COM L44385109 93,227 449,048 SH   DFND   0 0 449,048
GOLDEN MINERALS CO COM 381119106 31 46,847 SH   DFND   0 0 46,847
GOLDMAN SACHS GROUP INC COM 38141G104 389 1,191 SH   DFND   0 0 1,191
GOODRX HLDGS INC COM CL A 38246G108 643 16,466 SH   DFND   0 0 16,466
GREEN THUMB INDUSTRIES INC COM ISIN CA39342L1085 SEDOL BGDQBQ9 COMMONSTOCK 39342L108 13,650 460,064 SH   DFND   0 0 460,064
GREENLIGHT CAPITAL RE LTD CLASS A G4095J109 22 2,500 SH   DFND   0 0 2,500
GROCERY OUTLET HLDG CORP COM 39874R101 8 221 SH   DFND   0 0 221
GUARDANT HEALTH INC COM 40131M109 3,224 21,117 SH   DFND   0 0 21,117
H & E EQUIPMENT SERVICES INC COM 404030108 4,969 130,752 SH   DFND   0 0 130,752
HDFC BANK LTD SPONSORED ADS 40415F101 10,625 136,765 SH   DFND   0 0 136,765
HEALTHSTREAM INC COM 42222N103 8,887 397,797 SH   DFND   0 0 397,797
HEARUSA INC NEW COMMONSTOCK 422360305 0 375 SH   DFND   0 0 375
HEICO CORP NEW CL A 422806208 5,352 47,112 SH   DFND   0 0 47,112
HEICO CORP NEW COM 422806109 2,385 18,962 SH   DFND   0 0 18,962
HELLOFRESH SE ISIN DE000A161408 SEDOL BYWH8S0 COMMONSTOCK D3R2MA100 46,768 625,672 SH   DFND   0 0 625,672
HOME DEPOT INC COM 437076102 145 475 SH   DFND   0 0 475
HOUGHTON MIFFLIN HARCOURT CO COM 44157R109 922 120,945 SH   DFND   0 0 120,945
HUBSPOT INC COM 443573100 266,339 586,378 SH   DFND   0 0 586,378
ICICI BANK LIMITED ADR 45104G104 4,329 270,086 SH   DFND   0 0 270,086
IDEXX LABS INC COM 45168D104 4,688 9,580 SH   DFND   0 0 9,580
ILLUMINA INC COM 452327109 2,554 6,649 SH   DFND   0 0 6,649
IMPINJ INC COM 453204109 57,708 1,014,737 SH   DFND   0 0 1,014,737
INARI MED INC COM 45332Y109 23,816 222,581 SH   DFND   0 0 222,581
INFINERA CORP COM 45667G103 124,194 12,896,618 SH   DFND   0 0 12,896,618
INSPIRE MED SYS INC COM 457730109 176,911 854,682 SH   DFND   0 0 854,682
INSULET CORP COM 45784P101 4,757 18,230 SH   DFND   0 0 18,230
INTERBREW PLC GDREACH REPR 1 A SH REG S COMMONSTOCK 45845T308 0 200 SH   DFND   0 0 200
INTL GNRL INSURANCE HLDNGS L SHS G4809J106 18,582 2,274,416 SH   DFND   0 0 2,274,416
INTUITIVE SURGICAL INC COM NEW 46120E602 122,557 165,856 SH   DFND   0 0 165,856
INVITAE CORP COM 46185L103 266,618 6,977,691 SH   DFND   0 0 6,977,691
IRHYTHM TECHNOLOGIES INC COM 450056106 54,651 393,571 SH   DFND   0 0 393,571
IROBOT CORP COM 462726100 12 100 SH   DFND   0 0 100
IWG PLC ORD GBP001 ISIN JE00BYVQYS01 SEDOL BYVQYS0 COMMONSTOCK G4969N103 106 22,660 SH   DFND   0 0 22,660
JAMF HLDG CORP COM 47074L105 8,637 244,522 SH   DFND   0 0 244,522
JOHNSON & JOHNSON COM 478160104 134 815 SH   DFND   0 0 815
JPMORGAN CHASE & CO COM 46625H100 2,578 16,934 SH   DFND   0 0 16,934
JUST EAT TAKEAWAYCOM NV EUR004 144A REG S ISIN NL0012015705 COMMONSTOCK ZZDLN2RN7 755 8,177 SH   DFND   0 0 8,177
KADMON HLDGS INC COM 48283N106 1,874 481,808 SH   DFND   0 0 481,808
KAMBI GROUP PLC EUR0003 ISIN MT0000780107 SEDOL BMNQDC1 COMMONSTOCK X4170A107 66 1,230 SH   DFND   0 0 1,230
KB HOME COM 48666K109 426 9,154 SH   DFND   0 0 9,154
KENNEDY-WILSON HOLDINGS INC COM 489398107 51 2,500 SH   DFND   0 0 2,500
KINSALE CAP GROUP INC COM 49714P108 259 1,574 SH   DFND   0 0 1,574
KIRKLAND LAKE GOLD LTD COM 49741E100 4,936 146,025 SH   DFND   0 0 146,025
KORNIT DIGITAL LTD SHS M6372Q113 174,375 1,759,235 SH   DFND   0 0 1,759,235
KRYSTAL BIOTECH INC COM 501147102 521 6,769 SH   DFND   0 0 6,769
LEMONADE INC COM 52567D107 9,123 97,957 SH   DFND   0 0 97,957
LESLIES INC COM 527064109 25,633 1,046,686 SH   DFND   0 0 1,046,686
LGI HOMES INC COM 50187T106 54,926 367,867 SH   DFND   0 0 367,867
LI NING CO LTD HKD01 ISIN KYG5496K1242 SEDOL B01JCK9 COMMONSTOCK G5496K124 34 5,178 SH   DFND   0 0 5,178
LIBERTY MEDIA CORP DEL COM A BRAVES GRP 531229706 2,980 104,529 SH   DFND   0 0 104,529
LIBERTY MEDIA CORP DEL COM C BRAVES GRP 531229888 5,961 214,261 SH   DFND   0 0 214,261
LIBERTY MEDIA CORP DEL COM SER C FRMLA 531229854 1,696 39,180 SH   DFND   0 0 39,180
LINDBLAD EXPEDITIONS HLDGS I COM 535219109 18,755 992,334 SH   DFND   0 0 992,334
LIVE NATION ENTERTAINMENT IN COM 538034109 27 317 SH   DFND   0 0 317
LORAL SPACE & COM INC COM 543881106 23,797 631,735 SH   DFND   0 0 631,735
LOVESAC COMPANY COM 54738L109 1,575 27,833 SH   DFND   0 0 27,833
LULULEMON ATHLETICA INC COM 550021109 6,840 22,301 SH   DFND   0 0 22,301
LYFT INC CL A COM 55087P104 2,357 37,301 SH   DFND   0 0 37,301
MAG SILVER CORP COM 55903Q104 22,913 1,526,530 SH   DFND   0 0 1,526,530
MAGENTA THERAPEUTICS INC COM 55910K108 49,603 4,189,412 SH   DFND   0 0 4,189,412
MAGNOLIA OIL & GAS CORP CL A 559663109 7,589 661,088 SH   DFND   0 0 661,088
MARTIN MARIETTA MATLS INC COM 573284106 30,661 91,303 SH   DFND   0 0 91,303
MASTERCARD INCORPORATED CL A 57636Q104 27,788 78,045 SH   DFND   0 0 78,045
MATCH GROUP INC NEW COM 57667L107 15,537 113,093 SH   DFND   0 0 113,093
MAXAR TECHNOLOGIES INC COM 57778K105 52,119 1,378,093 SH   DFND   0 0 1,378,093
MERCADOLIBRE INC COM 58733R102 204,799 139,117 SH   DFND   0 0 139,117
MERCK & CO. INC COM 58933Y105 112 1,455 SH   DFND   0 0 1,455
MGP INGREDIENTS INC NEW COM 55303J106 1,384 23,400 SH   DFND   0 0 23,400
MICROSOFT CORP COM 594918104 70,938 300,878 SH   DFND   0 0 300,878
MOLECULAR TEMPLATES INC COM 608550109 1,597 126,541 SH   DFND   0 0 126,541
MONEYGRAM INTL INC COM NEW 60935Y208 3,681 560,235 SH   DFND   0 0 560,235
MONGODB INC CL A 60937P106 174,732 653,374 SH   DFND   0 0 653,374
MONOLITHIC PWR SYS INC COM 609839105 15,538 43,990 SH   DFND   0 0 43,990
NATERA INC COM 632307104 151,339 1,490,435 SH   DFND   0 0 1,490,435
NATIONAL VISION HLDGS INC COM 63845R107 29 659 SH   DFND   0 0 659
NEOPHOTONICS CORP COM 64051T100 995 83,271 SH   DFND   0 0 83,271
NESCO HLDGS INC COM 64083J104 11,531 1,233,237 SH   DFND   0 0 1,233,237
NETCOMPANY GROUP AS DKK1 144A ISIN DK0060952919 SEDOL BFYDWS1 COMMONSTOCK K7020C102 92,989 974,220 SH   DFND   0 0 974,220
NETFLIX INC COM 64110L106 537,264 1,029,912 SH   DFND   0 0 1,029,912
NEVRO CORP COM 64157F103 1,358 9,738 SH   DFND   0 0 9,738
NEW PACIFIC METALS CORP COM NPV ISIN CA64782A1075 SEDOL BMW590 COMMONSTOCK 64782A107 8,471 2,051,381 SH   DFND   0 0 2,051,381
NEW PROVIDENCE ACQUISITION COM CL A 64822P106 882 75,538 SH   DFND   0 0 75,538
NEW VISTA ACQUISITION CORP UNIT 02/01/2026 G6529L113 27,879 2,790,660 SH   DFND   0 0 2,790,660
NEW YORK TIMES CO CL A 650111107 136,694 2,700,391 SH   DFND   0 0 2,700,391
NIKE INC CL B 654106103 19,994 150,457 SH   DFND   0 0 150,457
NIU TECHNOLOGIES ADS 65481N100 21 586 SH   DFND   0 0 586
NORDSTROM INC COM 655664100 15 386 SH   DFND   0 0 386
NV5 GLOBAL INC COM 62945V109 62 644 SH   DFND   0 0 644
NVIDIA CORPORATION COM 67066G104 121,931 228,365 SH   DFND   0 0 228,365
NYXOAH SA NPV ISIN BE0974358906 SEDOL BN782G7 COMMONSTOCK B6S7WD106 7,179 303,892 SH   DFND   0 0 303,892
OAK STR HEALTH INC COM 67181A107 107,617 1,982,987 SH   DFND   0 0 1,982,987
OCADO GROUP PLC ORD GBP002 ISIN GB00B3MBS747 SEDOL B3MBS74 COMMONSTOCK G6718L106 285,622 10,172,852 SH   DFND   0 0 10,172,852
OKTA INC CL A 679295105 254,026 1,152,412 SH   DFND   0 0 1,152,412
OLO INC CL A 68134L109 489 18,523 SH   DFND   0 0 18,523
ONEWATER MARINE INC CL A COM 68280L101 39,670 992,745 SH   DFND   0 0 992,745
OPTION CARE HEALTH INC COM NEW 68404L201 31,386 1,769,242 SH   DFND   0 0 1,769,242
OSCAR HEALTH INC CL A 687793109 9,347 347,725 SH   DFND   0 0 347,725
OUTSET MED INC COM 690145107 3,712 68,247 SH   DFND   0 0 68,247
PACIFIC BIOSCIENCES CALIF IN COM 69404D108 676 20,306 SH   DFND   0 0 20,306
PALOMAR HLDGS INC COM 69753M105 8,399 125,282 SH   DFND   0 0 125,282
PAYPAL HLDGS INC COM 70450Y103 51,813 213,364 SH   DFND   0 0 213,364
PELOTON INTERACTIVE INC CL A COM 70614W100 381,481 3,392,750 SH   DFND   0 0 3,392,750
PENN NATL GAMING INC COM 707569109 62,135 592,665 SH   DFND   0 0 592,665
PENN TREATY AMERN CORP COM NEW COMMONSTOCK 707874400 0 125 SH   DFND   0 0 125
PENSKE AUTOMOTIVE GRP INC COM 70959W103 4,665 58,135 SH   DFND   0 0 58,135
PHATHOM PHARMACEUTICALS INC COM 71722W107 30,739 818,385 SH   DFND   0 0 818,385
PINDUODUO INC SPONSORED ADS 722304102 11,954 89,292 SH   DFND   0 0 89,292
PINTEREST INC CL A 72352L106 92,873 1,254,532 SH   DFND   0 0 1,254,532
PONTEM CORPORATION UNIT 99/99/9999 G71707114 5,150 520,203 SH   DFND   0 0 520,203
POOL CORP COM 73278L105 110,022 318,683 SH   DFND   0 0 318,683
PROFOUND MED CORP COM NEW 74319B502 3,500 173,784 SH   DFND   0 0 173,784
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PULMONX CORP COM 745848101 47,950 1,048,321 SH   DFND   0 0 1,048,321
PURECYCLE TECHNOLOGIES INC COM 74623V103 315 12,370 SH   DFND   0 0 12,370
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Q2 HLDGS INC COM 74736L109 26,323 262,708 SH   DFND   0 0 262,708
QORVO INC COM 74736K101 6,491 35,530 SH   DFND   0 0 35,530
QUALTRICS INTL INC COM CL A 747601201 356 10,827 SH   DFND   0 0 10,827
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QUANTERIX CORP COM 74766Q101 171,213 2,928,220 SH   DFND   0 0 2,928,220
QUIDEL CORP COM 74838J101 1 7 SH   DFND   0 0 7
REDFIN CORP COM 75737F108 43,454 652,561 SH   DFND   0 0 652,561
RELAY THERAPEUTICS INC COM 75943R102 69,847 2,020,461 SH   DFND   0 0 2,020,461
RENALYTIX AI PLC ADS 75973T101 77,527 3,021,317 SH   DFND   0 0 3,021,317
RENALYTIX AI PLC ORD GBP00025 ISIN GB00BYWL4Y04 SEDOL BYWL4Y0 COMMONSTOCK G7489R108 2,343 180,656 SH   DFND   0 0 180,656
REPARE THERAPEUTICS INC COM 760273102 99 3,233 SH   DFND   0 0 3,233
REPLIGEN CORP COM 759916109 90,964 467,899 SH   DFND   0 0 467,899
REVOLUTION ACCELERTN ACQU CO COM CL A 76156P106 284 27,983 SH   DFND   0 0 27,983
REYNA SILVER CORP COM NPV ISIN CA76170Q1063 SEDOL BMG11D0 COMMONSTOCK 76170Q106 1,673 2,311,045 SH   DFND   0 0 2,311,045
RHYTHM PHARMACEUTICALS INC COM 76243J105 32,399 1,523,234 SH   DFND   0 0 1,523,234
RIGHTMOVE ORD GBP0001 ISIN GB00BGDT3G23 SEDOL BGDT3G2 COMMONSTOCK G7565D106 6,806 847,312 SH   DFND   0 0 847,312
RINGCENTRAL INC CL A 76680R206 145,861 489,662 SH   DFND   0 0 489,662
ROBLOX CORP CL A 771049103 1,697 26,183 SH   DFND   0 0 26,183
RODGERS SILICON VALLEY AQ CO COM 774873103 16,574 1,245,226 SH   DFND   0 0 1,245,226
RODGERS SILICON VALLEY AQ CO UNIT 11/30/2025 774873202 16,898 1,137,153 SH   DFND   0 0 1,137,153
RODGERS SILICON VY ACQUISITION CORP UNIT 1 COM 12 WT EXP UNIT COMMONSTOCK 774NUS422 9,774 612,016 SH   DFND   0 0 612,016
ROKU INC COM CL A 77543R102 588,132 1,805,360 SH   DFND   0 0 1,805,360
ROYALTY PHARMA PLC SHS CLASS A G7709Q104 4,359 99,935 SH   DFND   0 0 99,935
SAFARICOM PLC KES005 ISIN KE1000001402 SEDOL B2QN3J6 COMMONSTOCK V74587102 30,545 92,140,277 SH   DFND   0 0 92,140,277
SAFETY INS GROUP INC COM 78648T100 107 1,269 SH   DFND   0 0 1,269
SALESFORCE COM INC COM 79466L302 35,178 166,034 SH   DFND   0 0 166,034
SANA BIOTECHNOLOGY INC COM 799566104 31,525 941,894 SH   DFND   0 0 941,894
SAREPTA THERAPEUTICS INC COM 803607100 600 8,049 SH   DFND   0 0 8,049
SCHRODINGER INC COM 80810D103 51,310 672,564 SH   DFND   0 0 672,564
SCIENTIFIC GAMES CORP COM 80874P109 419 10,886 SH   DFND   0 0 10,886
SCOTTS MIRACLE-GRO CO CL A 810186106 93,800 382,903 SH   DFND   0 0 382,903
SEMLER SCIENTIFIC INC COM USD0001 COMMONSTOCK 81684M104 5,954 55,390 SH   DFND   0 0 55,390
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SHAKE SHACK INC CL A 819047101 331,680 2,941,206 SH   DFND   0 0 2,941,206
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SHOALS TECHNOLOGIES GROUP IN CL A 82489W107 3,383 97,255 SH   DFND   0 0 97,255
SHOCKWAVE MED INC COM 82489T104 212,497 1,631,333 SH   DFND   0 0 1,631,333
SHOP APOTHEKE EUROPE NV NPV 144A REG S ISIN NL0012044747 SEDOL COMMONSTOCK N7975Z103 66,271 303,155 SH   DFND   0 0 303,155
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SIGNATURE BK NEW YORK N Y COM 82669G104 181 801 SH   DFND   0 0 801
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SILVERGATE CAP CORP CL A 82837P408 13,384 94,138 SH   DFND   0 0 94,138
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SITEONE LANDSCAPE SUPPLY INC COM 82982L103 42,362 248,106 SH   DFND   0 0 248,106
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WORKDAY INC CL A 98138H101 20,981 84,455 SH   DFND   0 0 84,455
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XP INC CL A G98239109 24,009 637,353 SH   DFND   0 0 637,353
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