The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| ACUTUS MED INC | COM | 005111109 | 3,409 | 255,000 | SH | SOLE | 255,000 | 0 | 0 | ||
| AERIE PHARMACEUTICALS INC | COM | 00771V108 | 14,089 | 788,410 | SH | SOLE | 788,410 | 0 | 0 | ||
| AKOUOS INC | COM | 00973J101 | 6,370 | 459,290 | SH | SOLE | 459,290 | 0 | 0 | ||
| ALIBABA GROUP HLDG LTD | SPONSORED ADS | 01609W102 | 48,708 | 214,827 | SH | SOLE | 214,827 | 0 | 0 | ||
| ALIGOS THERAPEUTICS INC | COM | 01626L105 | 59,455 | 2,614,563 | SH | SOLE | 2,614,563 | 0 | 0 | ||
| AMICUS THERAPEUTICS INC | COM | 03152W109 | 19,393 | 1,962,880 | SH | SOLE | 1,962,880 | 0 | 0 | ||
| APPLE INC | COM | 037833100 | 126,719 | 1,037,404 | SH | SOLE | 1,037,404 | 0 | 0 | ||
| BIOHAVEN PHARMACTL HLDG CO L | COM | G11196105 | 8,769 | 128,300 | SH | SOLE | 128,300 | 0 | 0 | ||
| BLUEPRINT MEDICINES CORP | COM | 09627Y109 | 19,154 | 197,000 | SH | SOLE | 197,000 | 0 | 0 | ||
| BOLT BIOTHERAPEUTICS INC | COM | 097702104 | 148,226 | 4,503,991 | SH | SOLE | 4,503,991 | 0 | 0 | ||
| BROOKFIELD ASSET MGMT INC | CL A LTD VT SH | 112585104 | 136,658 | 3,070,957 | SH | SOLE | 3,070,957 | 0 | 0 | ||
| CABLE ONE INC | COM | 12685J105 | 86,556 | 47,341 | SH | SOLE | 47,341 | 0 | 0 | ||
| CHECKMATE PHARMACEUTICALS IN | COM | 162818108 | 26,345 | 2,170,100 | SH | SOLE | 2,170,100 | 0 | 0 | ||
| CONSTELLATION PHARMCETICLS I | COM | 210373106 | 16,359 | 699,415 | SH | SOLE | 699,415 | 0 | 0 | ||
| CRINETICS PHARMACEUTICALS IN | COM | 22663K107 | 4,147 | 271,378 | SH | SOLE | 271,378 | 0 | 0 | ||
| EARGO INC | COM | 270087109 | 36,817 | 737,071 | SH | SOLE | 737,071 | 0 | 0 | ||
| EDGEWISE THERAPEUTICS INC | COM | 28036F105 | 181,584 | 5,587,207 | SH | SOLE | 5,587,207 | 0 | 0 | ||
| F-STAR THERAPEUTICS INC | COM | 30315R107 | 377 | 34,819 | SH | SOLE | 34,819 | 0 | 0 | ||
| FLEXION THERAPEUTICS INC | COM | 33938J106 | 12,560 | 1,403,370 | SH | SOLE | 1,403,370 | 0 | 0 | ||
| FREELINE THERAPEUTICS HLDGS | SPONSORED ADS | 35655L107 | 29,043 | 2,361,229 | SH | SOLE | 2,361,229 | 0 | 0 | ||
| GALECTO INC | COM | 36322Q107 | 15,162 | 2,497,791 | SH | SOLE | 2,497,791 | 0 | 0 | ||
| GALERA THERAPEUTICS INC | COM | 36338D108 | 21,689 | 2,459,021 | SH | SOLE | 2,459,021 | 0 | 0 | ||
| GRAYBUG VISION INC | COM SHS | 38942Q103 | 1,164 | 209,748 | SH | SOLE | 209,748 | 0 | 0 | ||
| GRITSTONE ONCOLOGY INC | COM | 39868T105 | 2,626 | 278,478 | SH | SOLE | 278,478 | 0 | 0 | ||
| HARMONY BIOSCIENCES HLDGS IN | COM | 413197104 | 110,234 | 3,336,378 | SH | SOLE | 3,336,378 | 0 | 0 | ||
| INARI MED INC | COM | 45332Y109 | 7,727 | 72,212 | SH | SOLE | 72,212 | 0 | 0 | ||
| INOGEN INC | COM | 45780L104 | 144,919 | 2,759,320 | SH | SOLE | 2,759,320 | 0 | 0 | ||
| INSMED INC | COM PAR $.01 | 457669307 | 15,553 | 456,631 | SH | SOLE | 456,631 | 0 | 0 | ||
| INSPIRE MED SYS INC | COM | 457730109 | 8,280 | 40,000 | SH | SOLE | 40,000 | 0 | 0 | ||
| INTERSECT ENT INC | COM | 46071F103 | 10,626 | 508,922 | SH | SOLE | 508,922 | 0 | 0 | ||
| INOZYME PHARMA INC | COM | 45790W108 | 38,994 | 1,969,379 | SH | SOLE | 1,969,379 | 0 | 0 | ||
| IOVANCE BIOTHERAPEUTICS INC | COM | 462260100 | 14,621 | 461,811 | SH | SOLE | 461,811 | 0 | 0 | ||
| KINNATE BIOPHARMA INC | COM | 49705R105 | 9,348 | 300,000 | SH | SOLE | 300,000 | 0 | 0 | ||
| LAVA THERAPEUTICS NV | SHS | N51517105 | 50,542 | 3,327,312 | SH | SOLE | 3,327,312 | 0 | 0 | ||
| LEGEND BIOTECH CORP | SPONSORED ADS | 52490G102 | 7,376 | 254,176 | SH | SOLE | 254,176 | 0 | 0 | ||
| MILESTONE PHARMACEUTICALS IN | COM | 59935V107 | 14,652 | 2,530,585 | SH | SOLE | 2,530,585 | 0 | 0 | ||
| MIRUM PHARMACEUTICALS INC | COM | 604749101 | 48,463 | 2,445,147 | SH | SOLE | 2,445,147 | 0 | 0 | ||
| MORPHIC HLDG INC | COM | 61775R105 | 167,404 | 2,645,446 | SH | SOLE | 2,645,446 | 0 | 0 | ||
| NKARTA INC | COM | 65487U108 | 91,918 | 2,793,864 | SH | SOLE | 2,793,864 | 0 | 0 | ||
| PHARVARIS N V | COM | N69605108 | 1,399 | 50,000 | SH | SOLE | 50,000 | 0 | 0 | ||
| PRAXIS PRECISION MEDICINES I | COM | 74006W108 | 80,003 | 2,442,080 | SH | SOLE | 2,442,080 | 0 | 0 | ||
| PROTAGONIST THERAPEUTICS INC | COM | 74366E102 | 22,474 | 867,724 | SH | SOLE | 867,724 | 0 | 0 | ||
| PULMONX CORP | COM | 745848101 | 8,556 | 187,047 | SH | SOLE | 187,047 | 0 | 0 | ||
| SEASPINE HLDGS CORP | COM | 81255T108 | 22,986 | 1,321,006 | SH | SOLE | 1,321,006 | 0 | 0 | ||
| SILK RD MED INC | COM | 82710M100 | 7,474 | 147,557 | SH | SOLE | 147,557 | 0 | 0 | ||
| SPERO THERAPEUTICS INC | COM | 84833T103 | 6,902 | 468,902 | SH | SOLE | 468,902 | 0 | 0 | ||
| SPRUCE BIOSCIENCES INC | COM | 85209E109 | 82,823 | 4,989,336 | SH | SOLE | 4,989,336 | 0 | 0 | ||
| VANGUARD INDEX FDS | TOTAL STK MKT | 922908769 | 399,718 | 1,933,900 | SH | SOLE | 1,933,900 | 0 | 0 | ||
| VAXCYTE INC | COM | 92243G108 | 8,235 | 416,937 | SH | SOLE | 416,937 | 0 | 0 | ||
| VERONA PHARMA PLC | SPONSORED ADS | 925050106 | 7,009 | 838,360 | SH | SOLE | 838,360 | 0 | 0 | ||
| ZOGENIX INC | COM NEW | 98978L204 | 7,943 | 406,915 | SH | SOLE | 406,915 | 0 | 0 | ||