The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
AES CORP COM 00130H105 86,948 3,243,120 SH   DFND 1, 2 1,387,579 0 1,855,541
ABBOTT LABS COM 002824100 70,213 585,889 SH   DFND 1, 2 343,859 0 242,030
ACTIVISION BLIZZARD INC COM 00507V109 58,397 627,921 SH   DFND 1, 2 350,459 0 277,462
ADAGENE INC ADS 005329107 6,870 382,714 SH   DFND 1, 2 382,714 0 0
ADOBE SYSTEMS INCORPORATED COM 00724F101 84,882 178,560 SH   DFND 1, 2 89,192 0 89,368
ADVANCED MICRO DEVICES INC COM 007903107 12,131 154,533 SH   DFND 1, 2 124,291 0 30,242
AIRBNB INC COM CL A 009066101 2,455 13,061 SH   DFND 1, 2 10,806 0 2,255
AIR LEASE CORP CL A 00912X302 2,765 56,419 SH   DFND 1, 2 56,419 0 0
AIR PRODS & CHEMS INC COM 009158106 42,371 150,605 SH   DFND 1, 2 43,584 0 107,021
ALLAKOS INC COM 01671P100 18,119 157,858 SH   DFND 1, 2 52,367 0 105,491
ALLEGHENY TECHNOLOGIES INC COM 01741R102 56,473 2,681,520 SH   DFND 1, 2 1,066,136 0 1,615,384
ALPHABET INC CAP STK CL C 02079K107 189,044 91,386 SH   DFND 1, 2 49,193 0 42,193
ALPHABET INC CAP STK CL A 02079K305 71,883 34,852 SH   DFND 1, 2 23,226 0 11,626
ALTERYX INC COM CL A 02156B103 3,931 47,389 SH   DFND 1, 2 38,158 0 9,231
ALTRIA GROUP INC COM 02209S103 1,730 33,824 SH   DFND 1, 2 33,824 0 0
AMAZON COM INC COM 023135106 232,300 75,079 SH   DFND 1, 2 48,334 0 26,745
AMERICA MOVIL SAB DE CV SPON ADR L SHS 02364W105 61,877 4,556,446 SH   DFND 1, 2 4,378,278 0 178,168
AMERICAN EXPRESS CO COM 025816109 5,063 35,798 SH   DFND 1, 2 35,798 0 0
AMERICAN TOWER CORP NEW COM 03027X100 8,506 35,583 SH   DFND 1, 2 33,553 0 2,030
AMETEK INC COM 031100100 46,957 367,625 SH   DFND 1, 2 140,018 0 227,607
ANGLOGOLD ASHANTI LIMITED SPONSORED ADR 035128206 3,193 145,354 SH   DFND 1, 2 126,795 0 18,559
ANHEUSER BUSCH INBEV SA/NV SPONSORED ADR 03524A108 393 6,253 SH   DFND 1, 2 6,253 0 0
ANTHEM INC COM 036752103 42,712 118,991 SH   DFND 1, 2 47,605 0 71,386
APPLE INC COM 037833100 103,126 844,253 SH   DFND 1, 2 539,963 0 304,290
ARCOSA INC COM 039653100 108,122 1,661,118 SH   DFND 1, 2 575,399 0 1,085,719
ARES MANAGEMENT CORPORATION CL A COM STK 03990B101 3,540 63,185 SH   DFND 1, 2 63,185 0 0
ARMSTRONG WORLD INDS INC NEW COM 04247X102 2,449 27,180 SH   DFND 1, 2 27,180 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108 1,887 37,961 SH   DFND 1, 2 37,961 0 0
AUTODESK INC COM 052769106 6,938 25,035 SH   DFND 1, 2 19,705 0 5,330
AZUL S A SPONSR ADR PFD 05501U106 7,433 368,146 SH   DFND 1, 2 368,146 0 0
BAKER HUGHES COMPANY CL A 05722G100 4,330 200,368 SH   DFND 1, 2 165,614 0 34,754
BK OF AMERICA CORP COM 060505104 68,891 1,780,596 SH   DFND 1, 2 810,406 0 970,190
BARRICK GOLD CORP COM 067901108 12,044 608,296 SH   DFND 1, 2 572,671 0 35,625
BAXTER INTL INC COM 071813109 4,369 51,801 SH   DFND 1, 2 41,997 0 9,804
BEIGENE LTD SPONSORED ADR 07725L102 360,587 1,035,930 SH   DFND 1, 2 921,501 0 114,429
BERKSHIRE HATHAWAY INC DEL CL B NEW 084670702 3,166 12,393 SH   DFND 1, 2 12,393 0 0
BILL COM HLDGS INC COM 090043100 39,885 274,122 SH   DFND 1, 2 99,683 0 174,439
BIONTECH SE SPONSORED ADS 09075V102 1,332 12,195 SH   DFND 1, 2 9,925 0 2,270
BLACKROCK INC COM 09247X101 20,894 27,713 SH   DFND 1, 2 22,185 0 5,528
BLACKSTONE GROUP INC COM 09260D107 3,481 46,709 SH   DFND 1, 2 46,709 0 0
BOEING CO COM 097023105 4,647 18,245 SH   DFND 1, 2 14,635 0 3,610
BOOKING HOLDINGS INC COM 09857L108 35,805 15,368 SH   DFND 1, 2 12,662 0 2,706
BROADCOM INC COM 11135F101 179,139 386,358 SH   DFND 1, 2 240,220 0 146,138
BROOKFIELD ASSET MGMT INC CL A LTD VT SH 112585104 5,832 131,064 SH   DFND 1, 2 119,157 0 11,907
BURLINGTON STORES INC COM 122017106 49,612 166,038 SH   DFND 1, 2 55,549 0 110,489
CDK GLOBAL INC COM 12508E101 47,734 882,979 SH   DFND 1, 2 410,999 0 471,980
CME GROUP INC COM 12572Q105 51,044 249,932 SH   DFND 1, 2 156,298 0 93,634
CMS ENERGY CORP COM 125896100 1,477 24,131 SH   DFND 1, 2 24,131 0 0
CSX CORP COM 126408103 47,462 492,244 SH   DFND 1, 2 211,036 0 281,208
CABLE ONE INC COM 12685J105 3,011 1,647 SH   DFND 1, 2 1,647 0 0
CANADIAN NATL RY CO COM 136375102 79,049 681,162 SH   DFND 1, 2 597,947 0 83,215
CARRIER GLOBAL CORPORATION COM 14448C104 90,368 2,140,404 SH   DFND 1, 2 1,041,291 0 1,099,113
CATALENT INC COM 148806102 6,620 62,861 SH   DFND 1, 2 50,676 0 12,185
CATERPILLAR INC COM 149123101 14,826 63,940 SH   DFND 1, 2 54,061 0 9,879
CELANESE CORP DEL COM 150870103 6,953 46,409 SH   DFND 1, 2 44,007 0 2,402
CELLECTIS S A SPON ADS 15117K103 18,456 913,231 SH   DFND 1, 2 782,192 0 131,039
CENTENE CORP DEL COM 15135B101 48,571 759,995 SH   DFND 1, 2 310,688 0 449,307
CENTERPOINT ENERGY INC COM 15189T107 38,743 1,710,496 SH   DFND 1, 2 579,789 0 1,130,707
CERIDIAN HCM HLDG INC COM 15677J108 474 5,622 SH   DFND 1, 2 3,781 0 1,841
CHARTER COMMUNICATIONS INC N CL A 16119P108 126,642 205,248 SH   DFND 1, 2 80,421 0 124,827
CHEVRON CORP NEW COM 166764100 38,050 363,104 SH   DFND 1, 2 172,204 0 190,900
CHIPOTLE MEXICAN GRILL INC COM 169656105 85,005 59,828 SH   DFND 1, 2 19,665 0 40,163
CHURCH & DWIGHT INC COM 171340102 46,178 528,659 SH   DFND 1, 2 186,169 0 342,490
CITIGROUP INC COM NEW 172967424 3,791 52,109 SH   DFND 1, 2 42,059 0 10,050
CITIZENS FINANCIAL GROUP INC COM 174610105 7,720 174,868 SH   DFND 1, 2 174,868 0 0
COMCAST CORP NEW CL A 20030N101 78,408 1,449,041 SH   DFND 1, 2 609,699 0 839,342
CONCENTRIX CORP COM 20602D101 1,626 10,863 SH   DFND 1, 2 10,863 0 0
CONOCOPHILLIPS COM 20825C104 84,174 1,589,095 SH   DFND 1, 2 806,863 0 782,232
CONSTELLATION BRANDS INC CL A 21036P108 22,274 97,695 SH   DFND 1, 2 24,860 0 72,835
COPART INC COM 217204106 10,629 97,868 SH   DFND 1, 2 78,912 0 18,956
COSTCO WHSL CORP NEW COM 22160K105 24,347 69,074 SH   DFND 1, 2 59,457 0 9,617
CREE INC COM 225447101 9,696 89,674 SH   DFND 1, 2 79,710 0 9,964
CROWN CASTLE INTL CORP NEW COM 22822V101 40,964 237,982 SH   DFND 1, 2 112,991 0 124,991
D R HORTON INC COM 23331A109 27,562 309,267 SH   DFND 1, 2 101,944 0 207,323
DANAHER CORPORATION COM 235851102 81,817 363,501 SH   DFND 1, 2 200,267 0 163,234
DANIMER SCIENTIFIC INC COM CL A 236272100 1,281 33,925 SH   DFND 1, 2 33,925 0 0
DEERE & CO COM 244199105 8,185 21,877 SH   DFND 1, 2 21,877 0 0
DELL TECHNOLOGIES INC CL C 24703L202 4,853 55,058 SH   DFND 1, 2 44,731 0 10,327
DELTA AIR LINES INC DEL COM NEW 247361702 9,096 188,410 SH   DFND 1, 2 151,691 0 36,719
DIGITAL RLTY TR INC COM 253868103 2,469 17,529 SH   DFND 1, 2 17,529 0 0
DISCOVER FINL SVCS COM 254709108 3,517 37,024 SH   DFND 1, 2 37,024 0 0
DOCUSIGN INC COM 256163106 5,079 25,087 SH   DFND 1, 2 19,598 0 5,489
DOLLAR GEN CORP NEW COM 256677105 45,991 226,981 SH   DFND 1, 2 87,973 0 139,008
DOLLAR TREE INC COM 256746108 28,139 245,844 SH   DFND 1, 2 80,374 0 165,470
DOMINOS PIZZA INC COM 25754A201 4,924 13,388 SH   DFND 1, 2 10,763 0 2,625
DOW INC COM 260557103 7,778 121,644 SH   DFND 1, 2 101,281 0 20,363
DUN & BRADSTREET HLDGS INC COM 26484T106 43,899 1,843,738 SH   DFND 1, 2 803,775 0 1,039,963
DUPONT DE NEMOURS INC COM 26614N102 2,683 34,721 SH   DFND 1, 2 28,350 0 6,371
EOG RES INC COM 26875P101 68,713 947,375 SH   DFND 1, 2 528,183 0 419,192
EAST WEST BANCORP INC COM 27579R104 6,165 83,539 SH   DFND 1, 2 83,539 0 0
EDWARDS LIFESCIENCES CORP COM 28176E108 59,191 707,685 SH   DFND 1, 2 352,718 0 354,967
ELECTRONIC ARTS INC COM 285512109 2,348 17,345 SH   DFND 1, 2 13,726 0 3,619
ENPHASE ENERGY INC COM 29355A107 24,810 152,994 SH   DFND 1, 2 50,122 0 102,872
EQUIFAX INC COM 294429105 64,111 353,950 SH   DFND 1, 2 161,873 0 192,077
EQUINIX INC COM 29444U700 71,882 105,773 SH   DFND 1, 2 50,070 0 55,703
EQUITRANS MIDSTREAM CORP COM 294600101 13,777 1,688,323 SH   DFND 1, 2 632,805 0 1,055,518
EXELON CORP COM 30161N101 307 7,014 SH   DFND 1, 2 7,014 0 0
EXTRA SPACE STORAGE INC COM 30225T102 565 4,260 SH   DFND 1, 2 4,260 0 0
FTI CONSULTING INC COM 302941109 3,170 22,622 SH   DFND 1, 2 22,622 0 0
FACEBOOK INC CL A 30303M102 268,546 911,777 SH   DFND 1, 2 534,846 0 376,931
FIDELITY NATL INFORMATION SV COM 31620M106 18,437 131,121 SH   DFND 1, 2 121,860 0 9,261
FIRST REP BK SAN FRANCISCO C COM 33616C100 209 1,256 SH   DFND 1, 2 1,256 0 0
FLEETCOR TECHNOLOGIES INC COM 339041105 51,808 192,859 SH   DFND 1, 2 90,427 0 102,432
GALAPAGOS NV SPON ADR 36315X101 1,561 20,246 SH   DFND 1, 2 20,246 0 0
GALLAGHER ARTHUR J & CO COM 363576109 227 1,817 SH   DFND 1, 2 1,817 0 0
GAMING & LEISURE PPTYS INC COM 36467J108 2,111 49,752 SH   DFND 1, 2 49,752 0 0
GENERAL ELECTRIC CO COM 369604103 1,605 122,247 SH   DFND 1, 2 103,290 0 18,957
GENERAL MLS INC COM 370334104 6,895 112,442 SH   DFND 1, 2 103,718 0 8,724
GENERAL MTRS CO COM 37045V100 5,198 90,460 SH   DFND 1, 2 72,522 0 17,938
GERDAU SA SPON ADR REP PFD 373737105 19,327 3,619,283 SH   DFND 1, 2 3,403,867 0 215,416
GILEAD SCIENCES INC COM 375558103 7,250 112,178 SH   DFND 1, 2 107,960 0 4,218
GLOBAL PMTS INC COM 37940X102 10,610 52,636 SH   DFND 1, 2 46,468 0 6,168
GODADDY INC CL A 380237107 67,750 872,846 SH   DFND 1, 2 558,093 0 314,753
GOL LINHAS AEREAS INTELIGENT SPON ADR PFD NEW 38045R206 8,921 1,166,100 SH   DFND 1, 2 1,166,100 0 0
GOLDMAN SACHS GROUP INC COM 38141G104 3,267 9,991 SH   DFND 1, 2 7,736 0 2,255
GRACELL BIOTECHNOLOGIES INC SPONSORED ADS 38406L103 13,595 882,768 SH   DFND 1, 2 882,768 0 0
GRIFOLS S A SP ADR REP B NVT 398438408 5,954 344,367 SH   DFND 1, 2 277,844 0 66,523
GUARDANT HEALTH INC COM 40131M109 4,085 26,762 SH   DFND 1, 2 26,762 0 0
HDFC BANK LTD SPONSORED ADS 40415F101 77,954 1,003,397 SH   DFND 1, 2 721,065 0 282,332
HEICO CORP NEW COM 422806109 1,640 13,038 SH   DFND 1, 2 13,038 0 0
HEICO CORP NEW CL A 422806208 36,171 318,405 SH   DFND 1, 2 109,125 0 209,280
HENRY JACK & ASSOC INC COM 426281101 288 1,899 SH   DFND 1, 2 1,899 0 0
HILTON GRAND VACATIONS INC COM 43283X105 68,786 1,834,779 SH   DFND 1, 2 734,476 0 1,100,303
HILTON WORLDWIDE HLDGS INC COM 43300A203 32,441 268,281 SH   DFND 1, 2 242,546 0 25,735
HOME DEPOT INC COM 437076102 17,627 57,747 SH   DFND 1, 2 46,515 0 11,232
HONEYWELL INTL INC COM 438516106 34,784 160,242 SH   DFND 1, 2 137,277 0 22,965
HUAZHU GROUP LTD SPONSORED ADS 44332N106 86,776 1,580,626 SH   DFND 1, 2 1,489,347 0 91,279
HUBSPOT INC COM 443573100 7,829 17,237 SH   DFND 1, 2 13,524 0 3,713
HUMANA INC COM 444859102 352 840 SH   DFND 1, 2 840 0 0
HUTCHISON CHINA MEDITECH LTD SPONSORED ADR 44842L103 133,071 4,710,475 SH   DFND 1, 2 4,248,169 0 462,306
HUYA INC ADS REP SHS A 44852D108 11,089 569,227 SH   DFND 1, 2 540,927 0 28,300
ICICI BANK LIMITED ADR 45104G104 113,115 7,056,477 SH   DFND 1, 2 6,257,529 0 798,948
IDEX CORP COM 45167R104 7,921 37,841 SH   DFND 1, 2 30,933 0 6,908
IDEXX LABS INC COM 45168D104 14,372 29,372 SH   DFND 1, 2 23,673 0 5,699
INCYTE CORP COM 45337C102 11,396 140,230 SH   DFND 1, 2 120,872 0 19,358
INFOSYS LTD SPONSORED ADR 456788108 3,424 182,910 SH   DFND 1, 2 134,650 0 48,260
INSULET CORP COM 45784P101 14,400 55,188 SH   DFND 1, 2 44,391 0 10,797
INTEL CORP COM 458140100 49,541 774,082 SH   DFND 1, 2 428,725 0 345,357
INTERCONTINENTAL EXCHANGE IN COM 45866F104 92,585 829,017 SH   DFND 1, 2 449,860 0 379,157
INTERNATIONAL FLAVORS&FRAGRA COM 459506101 8,689 62,241 SH   DFND 1, 2 50,340 0 11,901
INTUITIVE SURGICAL INC COM NEW 46120E602 36,215 49,009 SH   DFND 1, 2 39,423 0 9,586
IRIDIUM COMMUNICATIONS INC COM 46269C102 2,391 57,967 SH   DFND 1, 2 57,967 0 0
JPMORGAN CHASE & CO COM 46625H100 176,335 1,158,343 SH   DFND 1, 2 679,048 0 479,295
KLA CORP COM NEW 482480100 7,940 24,030 SH   DFND 1, 2 24,030 0 0
KARUNA THERAPEUTICS INC COM 48576A100 24,871 206,864 SH   DFND 1, 2 69,788 0 137,076
KEURIG DR PEPPER INC COM 49271V100 3,647 106,113 SH   DFND 1, 2 106,113 0 0
KRAFT HEINZ CO COM 500754106 35,617 890,419 SH   DFND 1, 2 297,924 0 592,495
L3HARRIS TECHNOLOGIES INC COM 502431109 51,151 252,375 SH   DFND 1, 2 87,525 0 164,850
LAM RESEARCH CORP COM 512807108 71,962 120,895 SH   DFND 1, 2 39,976 0 80,919
LAS VEGAS SANDS CORP COM 517834107 1,004 16,523 SH   DFND 1, 2 16,523 0 0
LAUDER ESTEE COS INC CL A 518439104 45,706 157,145 SH   DFND 1, 2 52,267 0 104,878
LEGEND BIOTECH CORP SPONSORED ADS 52490G102 55,627 1,916,845 SH   DFND 1, 2 1,916,845 0 0
LENNOX INTL INC COM 526107107 10,144 32,556 SH   DFND 1, 2 26,184 0 6,372
LIGHTSPEED POS INC SUB VTG SHS 53227R106 40,730 648,355 SH   DFND 1, 2 545,616 0 102,739
LILLY ELI & CO COM 532457108 17,391 93,087 SH   DFND 1, 2 85,241 0 7,846
LOCKHEED MARTIN CORP COM 539830109 961 2,601 SH   DFND 1, 2 2,601 0 0
LOMA NEGRA CORP SPONSORED ADS 54150E104 10,047 1,587,214 SH   DFND 1, 2 1,587,214 0 0
LUFAX HOLDING LTD ADS REP SHS CL A 54975P102 9,165 631,210 SH   DFND 1, 2 559,910 0 71,300
MSCI INC COM 55354G100 49,624 118,355 SH   DFND 1, 2 37,530 0 80,825
MARSH & MCLENNAN COS INC COM 571748102 56,312 462,329 SH   DFND 1, 2 169,619 0 292,710
MASTERCARD INCORPORATED CL A 57636Q104 146,562 411,633 SH   DFND 1, 2 209,580 0 202,053
MELCO RESORTS AND ENTMNT LTD ADR 585464100 4,314 216,699 SH   DFND 1, 2 175,814 0 40,885
MERCADOLIBRE INC COM 58733R102 98,486 66,900 SH   DFND 1, 2 56,889 0 10,011
MERCK & CO. INC COM 58933Y105 3,959 51,357 SH   DFND 1, 2 51,357 0 0
METTLER TOLEDO INTERNATIONAL COM 592688105 5,821 5,037 SH   DFND 1, 2 4,232 0 805
MICROSOFT CORP COM 594918104 292,725 1,241,570 SH   DFND 1, 2 741,721 0 499,849
MICRON TECHNOLOGY INC COM 595112103 115,591 1,310,404 SH   DFND 1, 2 524,449 0 785,955
MODERNA INC COM 60770K107 1,667 12,732 SH   DFND 1, 2 10,014 0 2,718
MOLSON COORS BEVERAGE CO CL B 60871R209 39,255 767,444 SH   DFND 1, 2 194,166 0 573,278
MONDELEZ INTL INC CL A 609207105 18,115 309,498 SH   DFND 1, 2 264,555 0 44,943
MONSTER BEVERAGE CORP NEW COM 61174X109 2,958 32,474 SH   DFND 1, 2 26,215 0 6,259
MOODYS CORP COM 615369105 88,813 297,422 SH   DFND 1, 2 171,569 0 125,853
MORGAN STANLEY COM NEW 617446448 3,639 46,856 SH   DFND 1, 2 35,847 0 11,009
MOTOROLA SOLUTIONS INC COM NEW 620076307 5,533 29,422 SH   DFND 1, 2 23,934 0 5,488
NVR INC COM 62944T105 3,415 725 SH   DFND 1, 2 725 0 0
NASDAQ INC COM 631103108 39,780 269,765 SH   DFND 1, 2 92,119 0 177,646
NETAPP INC COM 64110D104 10,795 148,553 SH   DFND 1, 2 148,553 0 0
NETFLIX INC COM 64110L106 145,545 279,004 SH   DFND 1, 2 159,511 0 119,493
NETEASE INC SPONSORED ADS 64110W102 54,259 525,460 SH   DFND 1, 2 501,174 0 24,286
NEUROCRINE BIOSCIENCES INC COM 64125C109 34,755 357,374 SH   DFND 1, 2 129,145 0 228,229
NEWMONT CORP COM 651639106 8,383 139,094 SH   DFND 1, 2 132,870 0 6,224
NEXTERA ENERGY INC COM 65339F101 236 3,127 SH   DFND 1, 2 3,127 0 0
NIKE INC CL B 654106103 73,386 552,228 SH   DFND 1, 2 316,021 0 236,207
NORFOLK SOUTHN CORP COM 655844108 3,777 14,065 SH   DFND 1, 2 14,065 0 0
NORTHROP GRUMMAN CORP COM 666807102 8,928 27,587 SH   DFND 1, 2 27,405 0 182
NOVO-NORDISK A S ADR 670100205 204 3,032 SH   DFND 1, 2 3,032 0 0
OAK STR HEALTH INC COM 67181A107 4,523 83,345 SH   DFND 1, 2 83,345 0 0
OKTA INC CL A 679295105 21,864 99,190 SH   DFND 1, 2 38,518 0 60,672
ON SEMICONDUCTOR CORP COM 682189105 78,592 1,888,774 SH   DFND 1, 2 849,944 0 1,038,830
ONECONNECT FINL TECHNOLOGY C SPONSORED ADS 68248T105 41,239 2,790,207 SH   DFND 1, 2 2,748,682 0 41,525
PG&E CORP COM 69331C108 4,405 376,211 SH   DFND 1, 2 376,211 0 0
PNC FINL SVCS GROUP INC COM 693475105 2,148 12,244 SH   DFND 1, 2 12,244 0 0
PARK HOTELS & RESORTS INC COM 700517105 64,964 3,010,390 SH   DFND 1, 2 975,665 0 2,034,725
PAYCHEX INC COM 704326107 1,011 10,311 SH   DFND 1, 2 10,311 0 0
PAYPAL HLDGS INC COM 70450Y103 117,443 483,623 SH   DFND 1, 2 292,080 0 191,543
PEPSICO INC COM 713448108 1,311 9,268 SH   DFND 1, 2 9,268 0 0
PETROLEO BRASILEIRO SA PETRO SPONSORED ADR 71654V408 3,570 420,967 SH   DFND 1, 2 420,967 0 0
PFIZER INC COM 717081103 14,237 392,967 SH   DFND 1, 2 318,152 0 74,815
PHILIP MORRIS INTL INC COM 718172109 84,099 947,703 SH   DFND 1, 2 520,618 0 427,085
PINDUODUO INC SPONSORED ADS 722304102 4,178 31,205 SH   DFND 1, 2 31,205 0 0
PINTEREST INC CL A 72352L106 2,578 34,826 SH   DFND 1, 2 34,826 0 0
PROCTER AND GAMBLE CO COM 742718109 677 4,998 SH   DFND 1, 2 4,998 0 0
QIWI PLC SPON ADR REP B 74735M108 4,287 402,508 SH   DFND 1, 2 402,508 0 0
QUALCOMM INC COM 747525103 1,058 7,978 SH   DFND 1, 2 7,978 0 0
QUALTRICS INTL INC COM CL A 747601201 2,189 66,517 SH   DFND 1, 2 66,517 0 0
RAYTHEON TECHNOLOGIES CORP COM 75513E101 2,814 36,414 SH   DFND 1, 2 36,414 0 0
REGENERON PHARMACEUTICALS COM 75886F107 17,314 36,594 SH   DFND 1, 2 29,458 0 7,136
RESTAURANT BRANDS INTL INC COM 76131D103 8,028 123,503 SH   DFND 1, 2 99,953 0 23,550
RYANAIR HOLDINGS PLC SPONSORED ADS 783513203 89,713 780,111 SH   DFND 1, 2 641,516 0 138,595
S&P GLOBAL INC COM 78409V104 11,404 32,317 SH   DFND 1, 2 29,160 0 3,157
SVB FINANCIAL GROUP COM 78486Q101 75,136 152,202 SH   DFND 1, 2 64,354 0 87,848
SAGE THERAPEUTICS INC COM 78667J108 1,305 17,429 SH   DFND 1, 2 17,429 0 0
SCHLUMBERGER LTD COM 806857108 14,693 540,396 SH   DFND 1, 2 471,969 0 68,427
SEA LTD SPONSORD ADS 81141R100 48,934 219,208 SH   DFND 1, 2 203,927 0 15,281
SEAGEN INC COM 81181C104 89,006 640,974 SH   DFND 1, 2 328,267 0 312,707
SEMPRA ENERGY COM 816851109 17,658 133,187 SH   DFND 1, 2 125,133 0 8,054
SERVICENOW INC COM 81762P102 75,090 150,147 SH   DFND 1, 2 72,821 0 77,326
SHERWIN WILLIAMS CO COM 824348106 41,997 56,906 SH   DFND 1, 2 30,628 0 26,278
SHOPIFY INC CL A 82509L107 32,372 29,256 SH   DFND 1, 2 23,434 0 5,822
SMARTSHEET INC COM CL A 83200N103 11,814 184,832 SH   DFND 1, 2 147,840 0 36,992
SNAP INC CL A 83304A106 4,914 93,974 SH   DFND 1, 2 73,753 0 20,221
STATE STR CORP COM 857477103 458 5,450 SH   DFND 1, 2 5,450 0 0
TFI INTL INC COM 87241L109 54,851 731,755 SH   DFND 1, 2 648,078 0 83,677
TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADS 874039100 174,768 1,477,579 SH   DFND 1, 2 1,024,621 0 452,958
TANDEM DIABETES CARE INC COM NEW 875372203 4,385 49,688 SH   DFND 1, 2 39,763 0 9,925
TC ENERGY CORP COM 87807B107 11,141 243,044 SH   DFND 1, 2 222,251 0 20,793
TELADOC HEALTH INC COM 87918A105 1,039 5,719 SH   DFND 1, 2 4,345 0 1,374
TELUS INTL CDA INC SUB VTG SHS 87975H100 43,139 1,541,793 SH   DFND 1, 2 1,319,995 0 221,798
TESLA INC COM 88160R101 243,722 364,892 SH   DFND 1, 2 293,604 0 71,288
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS 881624209 6,586 570,721 SH   DFND 1, 2 497,891 0 72,830
TEXAS INSTRS INC COM 882508104 1,486 7,861 SH   DFND 1, 2 7,861 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102 27,192 59,583 SH   DFND 1, 2 48,002 0 11,581
TOLL BROTHERS INC COM 889478103 3,972 70,013 SH   DFND 1, 2 70,013 0 0
TRANSDIGM GROUP INC COM 893641100 76,261 129,713 SH   DFND 1, 2 64,624 0 65,089
TRAVELERS COMPANIES INC COM 89417E109 3,046 20,253 SH   DFND 1, 2 20,253 0 0
TRIMBLE INC COM 896239100 98,711 1,268,941 SH   DFND 1, 2 599,817 0 669,124
TRINITY INDS INC COM 896522109 2,773 97,338 SH   DFND 1, 2 97,338 0 0
TRIP COM GROUP LTD ADS 89677Q107 80,385 2,028,386 SH   DFND 1, 2 1,873,317 0 155,069
TRUIST FINL CORP COM 89832Q109 2,602 44,614 SH   DFND 1, 2 44,614 0 0
TWITTER INC COM 90184L102 3,773 59,302 SH   DFND 1, 2 47,764 0 11,538
UBER TECHNOLOGIES INC COM 90353T100 7,921 145,304 SH   DFND 1, 2 116,744 0 28,560
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 48,272 423,957 SH   DFND 1, 2 197,230 0 226,727
UNION PAC CORP COM 907818108 490 2,224 SH   DFND 1, 2 2,224 0 0
UNITEDHEALTH GROUP INC COM 91324P102 75,876 203,929 SH   DFND 1, 2 96,806 0 107,123
V F CORP COM 918204108 3,588 44,889 SH   DFND 1, 2 43,754 0 1,135
VALE S A SPONSORED ADS 91912E105 219,047 12,603,384 SH   DFND 1, 2 10,842,034 0 1,761,350
VERISIGN INC COM 92343E102 22,939 115,412 SH   DFND 1, 2 60,082 0 55,330
VERTEX PHARMACEUTICALS INC COM 92532F100 24,915 115,943 SH   DFND 1, 2 93,750 0 22,193
VIATRIS INC COM 92556V106 276 19,749 SH   DFND 1, 2 16,207 0 3,542
VICI PPTYS INC COM 925652109 3,857 136,566 SH   DFND 1, 2 136,566 0 0
VIR BIOTECHNOLOGY INC COM 92764N102 3,363 65,586 SH   DFND 1, 2 52,306 0 13,280
VISA INC COM CL A 92826C839 129,710 612,621 SH   DFND 1, 2 361,327 0 251,294
WALGREENS BOOTS ALLIANCE INC COM 931427108 9,698 176,649 SH   DFND 1, 2 143,786 0 32,863
WASTE CONNECTIONS INC COM 94106B101 52,173 483,172 SH   DFND 1, 2 175,313 0 307,859
WASTE MGMT INC DEL COM 94106L109 253 1,964 SH   DFND 1, 2 1,964 0 0
WORKDAY INC CL A 98138H101 2,800 11,270 SH   DFND 1, 2 8,754 0 2,516
WYNN RESORTS LTD COM 983134107 42,673 340,375 SH   DFND 1, 2 85,229 0 255,146
XPENG INC ADS 98422D105 34,344 940,685 SH   DFND 1, 2 853,229 0 87,456
YUM BRANDS INC COM 988498101 47,055 434,971 SH   DFND 1, 2 183,539 0 251,432
ZENDESK INC COM 98936J101 7,743 58,384 SH   DFND 1, 2 45,891 0 12,493
ZIMMER BIOMET HOLDINGS INC COM 98956P102 2,155 13,464 SH   DFND 1, 2 13,464 0 0
ZOETIS INC CL A 98978V103 19,789 125,662 SH   DFND 1, 2 101,336 0 24,326
AON PLC SHS CL A G0403H108 92,407 401,578 SH   DFND 1, 2 140,637 0 260,941
ARCH CAP GROUP LTD ORD G0450A105 9,666 251,913 SH   DFND 1, 2 203,261 0 48,652
ATLASSIAN CORP PLC CL A G06242104 40,613 192,697 SH   DFND 1, 2 165,389 0 27,308
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 39,873 583,367 SH   DFND 1, 2 200,715 0 382,652
BUNGE LIMITED COM G16962105 3,827 48,272 SH   DFND 1, 2 41,141 0 7,131
EVEREST RE GROUP LTD COM G3223R108 7,513 30,316 SH   DFND 1, 2 27,195 0 3,121
FABRINET SHS G3323L100 2,988 33,052 SH   DFND 1, 2 33,052 0 0
GENPACT LIMITED SHS G3922B107 29,631 691,995 SH   DFND 1, 2 691,995 0 0
HELEN OF TROY LTD COM G4388N106 2,830 13,436 SH   DFND 1, 2 13,436 0 0
LINDE PLC SHS G5494J103 12,996 46,390 SH   DFND 1, 2 39,344 0 7,046
NOVOCURE LTD ORD SHS G6674U108 15,765 119,271 SH   DFND 1, 2 102,988 0 16,283
PAGSEGURO DIGITAL LTD COM CL A G68707101 49,096 1,060,379 SH   DFND 1, 2 989,895 0 70,484
PATRIA INVESTMENTS LIMITED COM CL A G69451105 18,300 1,050,526 SH   DFND 1, 2 1,050,526 0 0
RENAISSANCERE HLDGS LTD COM G7496G103 40,587 253,275 SH   DFND 1, 2 97,429 0 155,846
ROYALTY PHARMA PLC SHS CLASS A G7709Q104 39,070 895,685 SH   DFND 1, 2 246,735 0 648,950
VINCI PARTNERS INVTS LTD COM CL A G9451V109 5,408 411,243 SH   DFND 1, 2 411,243 0 0
WILLIS TOWERS WATSON PLC LTD SHS G96629103 2,592 11,325 SH   DFND 1, 2 9,059 0 2,266
CHUBB LIMITED COM H1467J104 71,718 453,997 SH   DFND 1, 2 238,216 0 215,781
CRISPR THERAPEUTICS AG NAMEN AKT H17182108 8,619 70,735 SH   DFND 1, 2 58,130 0 12,605
UBS GROUP AG SHS H42097107 36,677 2,367,565 SH   DFND 1, 2 2,116,423 0 251,142
LOGITECH INTL S A SHS H50430232 45,665 435,345 SH   DFND 1, 2 363,690 0 71,655
TE CONNECTIVITY LTD REG SHS H84989104 15,417 119,412 SH   DFND 1, 2 96,233 0 23,179
NEXA RES S A COM L67359106 8,672 846,055 SH   DFND 1, 2 846,055 0 0
SPOTIFY TECHNOLOGY S A SHS L8681T102 7,352 27,438 SH   DFND 1, 2 27,438 0 0
ASML HOLDING N V N Y REGISTRY SHS N07059210 260,931 422,656 SH   DFND 1, 2 254,381 0 168,275
ELASTIC N V ORD SHS N14506104 2,077 18,680 SH   DFND 1, 2 18,680 0 0
LYONDELLBASELL INDUSTRIES N SHS - A - N53745100 20,458 196,618 SH   DFND 1, 2 164,286 0 32,332
STELLANTIS N.V SHS N82405106 7,904 446,714 SH   DFND 1, 2 357,293 0 89,421
YANDEX N V SHS CLASS A N97284108 194,695 3,039,254 SH   DFND 1, 2 2,723,204 0 316,050
MAKEMYTRIP LIMITED MAURITIUS SHS V5633W109 7,352 232,813 SH   DFND 1, 2 232,813 0 0
ROYAL CARIBBEAN GROUP COM V7780T103 62,794 733,490 SH   DFND 1, 2 327,366 0 406,124