The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACCELERON PHARMA INC COM 00434H108 6,102 45,000 SH   SOLE   45,000 0 0
ACHILLES THERAPEUTICS PLC SPONSORED ADS 00449L102 414 25,000 SH   SOLE   25,000 0 0
ACLARIS THERAPEUTICS INC COM 00461U105 5,601 222,267 SH   SOLE   222,267 0 0
ACUTUS MED INC COM 005111109 802 60,000 SH   SOLE   60,000 0 0
ALDEYRA THERAPEUTICS INC COM 01438T106 3,564 300,000 SH   SOLE   300,000 0 0
ARK ETF TR GENOMIC REV ETF 00214Q302 21,295 240,000 SH Put SOLE   240,000 0 0
ARYA SCIENCES ACQU CORP IV CL A G31659108 7,331 700,000 SH   SOLE   700,000 0 0
ARYA SCIENCES ACQUISITION CO COM CL A G3166W106 9,494 689,000 SH   SOLE   689,000 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101 2,578 20,000 SH   SOLE   20,000 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101 2,578 20,000 SH Put SOLE   20,000 0 0
ASLAN PHARMACEUTICALS LTD ADS 04522R101 670 200,000 SH   SOLE   200,000 0 0
AXSOME THERAPEUTICS INC COM 05464T104 566 10,000 SH   SOLE   10,000 0 0
BCTG ACQUISITION CORP COM 05492W103 1,112 100,000 SH   SOLE   100,000 0 0
BELLUS HEALTH INC NEW COM NEW 07987C204 1,152 300,000 SH   SOLE   300,000 0 0
BEYONDSPRING INC SHS G10830100 554 50,000 SH   SOLE   50,000 0 0
BLUEBIRD BIO INC COM 09609G100 1,508 50,000 SH Call SOLE   50,000 0 0
BRIDGEBIO PHARMA INC COM 10806X102 35,574 577,500 SH   SOLE   577,500 0 0
BUTTERFLY NETWORK INC COM CL A 124155102 1,683 100,000 SH   SOLE   100,000 0 0
C4 THERAPEUTICS INC COM STK 12529R107 740 20,000 SH   SOLE   20,000 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 2,678 130,000 SH   SOLE   130,000 0 0
CEREVEL THERAPEUTICS HLDNG I *W EXP 06/09/2020 15678U102 312 72,466 SH   SOLE   72,466 0 0
CEREVEL THERAPEUTICS HLDNG I COM 15678U128 3,707 270,000 SH   SOLE   270,000 0 0
CHARDAN HEALTHCR ACQSTN 2 CO UNIT 99/99/9999 15957T206 789 75,000 SH   SOLE   75,000 0 0
CHINOOK THERAPEUTICS INC COM 16961L106 2,720 175,000 SH   SOLE   175,000 0 0
CURIS INC COM NEW 231269200 11,320 1,000,000 SH   SOLE   1,000,000 0 0
CURIS INC COM NEW 231269200 2,830 250,000 SH Call SOLE   250,000 0 0
CYCLACEL PHARMACEUTICALS INC COM 23254L603 2,702 380,000 SH   SOLE   380,000 0 0
CYTOKINETICS INC COM NEW 23282W605 930 40,000 SH   SOLE   40,000 0 0
CYTOMX THERAPEUTICS INC COM 23284F105 387 50,000 SH   SOLE   50,000 0 0
EPIZYME INC COM 29428V104 436 50,000 SH   SOLE   50,000 0 0
ESSA PHARMA INC COM NEW 29668H708 2,615 90,000 SH   SOLE   90,000 0 0
ESTABLISHMENT LABS HLDGS INC COM G31249108 625 10,000 SH   SOLE   10,000 0 0
GALAPAGOS NV SPON ADR 36315X101 964 12,500 SH   SOLE   12,500 0 0
GLOBAL BLOOD THERAPEUTICS IN COM 37890U108 815 20,000 SH   SOLE   20,000 0 0
HARPOON THERAPEUTICS INC COM 41358P106 418 20,000 SH   SOLE   20,000 0 0
HEALTH SCIENCES ACQ CORP 2 ORD SHS G4411D109 2,518 225,000 SH   SOLE   225,000 0 0
HIGHCAPE CAP ACQUISITION COR COM SL A 42984L105 1,788 150,000 SH   SOLE   150,000 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 3,221 35,000 SH   SOLE   35,000 0 0
IMMATICS N.V *W EXP 07/01/2020 N44445117 590 200,000 SH   SOLE   200,000 0 0
IMMUNOVANT INC COM 45258J102 1,123 70,000 SH Call SOLE   70,000 0 0
INARI MED INC COM 45332Y109 5,350 50,000 SH   SOLE   50,000 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100 779 24,600 SH   SOLE   24,600 0 0
KALVISTA PHARMACEUTICALS INC COM 483497103 2,569 100,000 SH   SOLE   100,000 0 0
KURA ONCOLOGY INC COM 50127T109 10,319 365,000 SH   SOLE   365,000 0 0
LIFESCI ACQUISITION II CORP COM 53229E103 4,056 400,000 SH   SOLE   400,000 0 0
MACROGENICS INC COM 556099109 796 25,000 SH   SOLE   25,000 0 0
MEDICUS SCIENCES ACQUISITION UNIT 99/99/9999 G5960S116 2,955 300,000 SH   SOLE   300,000 0 0
MEREO BIOPHARMA GROUP PLC ADS 589492107 3,033 900,000 SH   SOLE   900,000 0 0
MERSANA THERAPEUTICS INC COM 59045L106 1,375 85,000 SH   SOLE   85,000 0 0
MODERNA INC COM 60770K107 655 5,000 SH Call SOLE   5,000 0 0
MORPHIC HLDG INC COM 61775R105 12,340 195,000 SH   SOLE   195,000 0 0
OCULAR THERAPEUTIX INC COM 67576A100 3,733 227,500 SH   SOLE   227,500 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102 1,295 50,000 SH   SOLE   50,000 0 0
PULMONX CORP COM 745848101 2,058 45,000 SH   SOLE   45,000 0 0
RETROPHIN INC NOTE 2.500% 9/1 761299AB2 4,069 4,000,000 PRN   SOLE   4,000,000 0 0
ROCKET PHARMACEUTICALS INC COM 77313F106 3,771 85,000 SH   SOLE   85,000 0 0
RUBIUS THERAPEUTICS INC COM 78116T103 1,855 70,000 SH Call SOLE   70,000 0 0
SPDR S&P 500 ETF TR TR UNIT 78462F103 43,596 110,000 SH Put SOLE   110,000 0 0
SPRINGWORKS THERAPEUTICS INC COM 85205L107 1,986 27,000 SH   SOLE   27,000 0 0
SUTRO BIOPHARMA INC COM 869367102 1,821 80,000 SH   SOLE   80,000 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105 4,260 190,500 SH Call SOLE   190,500 0 0
TRAVERE THERAPEUTICS INC COM 89422G107 5,493 220,000 SH   SOLE   220,000 0 0
VAXCYTE INC COM 92243G108 593 30,000 SH   SOLE   30,000 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 10,745 50,000 SH Call SOLE   50,000 0 0
VESPER HEALTHCARE ACQSTN COR *W EXP 09/30/2027 92538T112 94 45,000 SH   SOLE   45,000 0 0
VINCERX PHARMA INC *W EXP 12/24/2025 92731L114 881 218,000 SH   SOLE   218,000 0 0
VINCERX PHARMA INC COM NEW 92731L106 10,480 543,010 SH   SOLE   543,010 0 0
WINDTREE THERAPEUTICS INC COM 97382D303 105 42,847 SH   SOLE   42,847 0 0
X4 PHARMACEUTICALS INC COM 98420X103 646 75,000 SH   SOLE   75,000 0 0
ZENTALIS PHARMACEUTICALS INC COM 98943L107 3,363 77,500 SH   SOLE   77,500 0 0
ZYMEWORKS INC COM 98985W102 2,526 80,000 SH   SOLE   80,000 0 0
ZYNERBA PHARMACEUTICALS INC COM 98986X109 62 13,285 SH   SOLE   13,285 0 0