The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACADIA PHARMACEUTICALS INC COM 004225108 10,836 420,000 SH   SOLE   420,000 0 0
ACCELERON PHARMA INC COM 00434H108 32,815 241,981 SH   SOLE   241,981 0 0
AFFIMED N V COM N01045108 8,275 1,046,129 SH   SOLE   1,046,129 0 0
AGILENT TECHNOLOGIES INC COM 00846U101 1,940 15,261 SH   SOLE   15,261 0 0
ALEXION PHARMACEUTICALS INC COM 015351109 71,253 465,983 SH   SOLE   465,983 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 11,427 80,937 SH   SOLE   80,937 0 0
ALPHA HEALTHCARE ACQUISTN CO CL A 020751103 2,589 239,026 SH   SOLE   239,026 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206 104,929 16,896,796 SH   SOLE   16,896,796 0 0
AMNEAL PHARMACEUTICALS INC COM STK CL A 03168L105 32,004 4,755,480 SH   SOLE   4,755,480 0 0
ANTHEM INC COM 036752103 22,934 63,892 SH   SOLE   63,892 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106 554 12,900 SH   SOLE   12,900 0 0
APTOSE BIOSCIENCES INC COM NEW 03835T200 478 80,000 SH   SOLE   80,000 0 0
ARGENX SE SPONSORED ADR 04016X101 9,883 35,886 SH   SOLE   35,886 0 0
ARK ETF TR GENOMIC REV ETF 00214Q302 71,599 806,932 SH   SOLE   806,932 0 0
ARK ETF TR INNOVATION ETF 00214Q104 9,836 82,000 SH   SOLE   82,000 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101 40,193 311,867 SH   SOLE   311,867 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108 49,338 992,315 SH   SOLE   992,315 0 0
AVANTOR INC COM 05352A100 27,743 958,987 SH   SOLE   958,987 0 0
BECTON DICKINSON & CO COM 075887109 16,627 68,383 SH   SOLE   68,383 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 16,552 242,172 SH   SOLE   242,172 0 0
CABALETTA BIO INC COM 12674W109 853 76,849 SH   SOLE   76,849 0 0
CATALENT INC COM 148806102 17,178 163,114 SH   SOLE   163,114 0 0
CENTENE CORP DEL COM 15135B101 5,823 91,120 SH   SOLE   91,120 0 0
CHEWY INC CL A 16679L109 1,110 13,100 SH   SOLE   13,100 0 0
CIGNA CORP NEW COM 125523100 9,670 40,000 SH   SOLE   40,000 0 0
COMMUNITY HEALTH SYS INC NEW COM 203668108 32,527 2,405,834 SH   SOLE   2,405,834 0 0
CONFORMIS INC COM 20717E101 1,527 1,541,978 SH   SOLE   1,541,978 0 0
DANAHER CORPORATION COM 235851102 39,991 177,534 SH   SOLE   177,534 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 15,502 345,717 SH   SOLE   345,717 0 0
DEXCOM INC COM 252131107 6,735 18,741 SH   SOLE   18,741 0 0
ENSIGN GROUP INC COM 29358P101 2,712 28,883 SH   SOLE   28,883 0 0
ENVISTA HOLDINGS CORPORATION COM 29415F104 29,894 732,684 SH   SOLE   732,684 0 0
EXAGEN INC COM 30068X103 1,828 104,437 SH   SOLE   104,437 0 0
FATE THERAPEUTICS INC COM 31189P102 26,529 321,760 SH   SOLE   321,760 0 0
FIVE PRIME THERAPEUTICS INC COM 33830X104 3,514 93,280 SH   SOLE   93,280 0 0
GLAXOSMITHKLINE PLC SPONSORED ADR 37733W105 31,057 852,206 SH   SOLE   852,206 0 0
GOHEALTH INC COM CL A 38046W105 805 68,899 SH   SOLE   68,899 0 0
GUARDANT HEALTH INC COM 40131M109 6,144 40,247 SH   SOLE   40,247 0 0
HCA HEALTHCARE INC COM 40412C101 16,086 85,409 SH   SOLE   85,409 0 0
HESKA CORP COM RESTRC NEW 42805E306 1,860 11,040 SH   SOLE   11,040 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 64,010 695,459 SH   SOLE   695,459 0 0
HUMANA INC COM 444859102 10,438 24,839 SH   SOLE   24,839 0 0
IMMUNOVANT INC COM 45258J102 3,692 230,183 SH   SOLE   230,183 0 0
IMMUTEP LTD SPONSORED ADS 45257L108 767 249,895 SH   SOLE   249,895 0 0
INFLARX NV COM N44821101 1,048 268,634 SH   SOLE   268,634 0 0
INTERSECT ENT INC COM 46071F103 1,574 75,389 SH   SOLE   75,389 0 0
INTRA CELLULAR THERAPIES INC COM 46116X101 10,199 300,587 SH   SOLE   300,587 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602 1,909 2,583 SH   SOLE   2,583 0 0
IQVIA HLDGS INC COM 46266C105 1,144 5,921 SH   SOLE   5,921 0 0
KADMON HLDGS INC COM 48283N106 5,341 1,373,119 SH   SOLE   1,373,119 0 0
KEROS THERAPEUTICS INC COM 492327101 1,701 27,631 SH   SOLE   27,631 0 0
LEXICON PHARMACEUTICALS INC COM NEW 528872302 2,410 410,593 SH   SOLE   410,593 0 0
LIQUIDIA CORPORATION COM NEW 53635D202 1,345 500,010 SH   SOLE   500,010 0 0
LUMINEX CORP DEL COM 55027E102 4,333 135,471 SH   SOLE   135,471 0 0
MAGELLAN HEALTH INC COM NEW 559079207 9,762 104,700 SH   SOLE   104,700 0 0
MANNKIND CORP COM NEW 56400P706 8,488 2,165,383 SH   SOLE   2,165,383 0 0
MCKESSON CORP COM 58155Q103 23,987 122,983 SH   SOLE   122,983 0 0
NATERA INC COM 632307104 5,859 57,700 SH   SOLE   57,700 0 0
NOVAVAX INC COM NEW 670002401 6,069 33,473 SH   SOLE   33,473 0 0
ORTHO CLINICAL DIAGNOSTICS H ORD SHS G6829J107 26,535 1,375,228 SH   SOLE   1,375,228 0 0
PROTHENA CORP PLC SHS G72800108 1,723 68,575 SH   SOLE   68,575 0 0
QIAGEN NV SHS NEW N72482123 22,140 454,721 SH   SOLE   454,721 0 0
QUIDEL CORP COM 74838J101 529 4,132 SH   SOLE   4,132 0 0
REPLIGEN CORP COM 759916109 278 1,428 SH   SOLE   1,428 0 0
RITE AID CORP COM 767754872 1,105 54,025 SH   SOLE   54,025 0 0
SERES THERAPEUTICS INC COM 81750R102 4,433 215,276 SH   SOLE   215,276 0 0
SURGALIGN HOLDINGS INC COM 86882C105 5,755 2,639,784 SH   SOLE   2,639,784 0 0
SURMODICS INC COM 868873100 2,686 47,906 SH   SOLE   47,906 0 0
TARO PHARMACEUTICAL INDS LTD SHS M8737E108 12,123 164,378 SH   SOLE   164,378 0 0
TELIGENT INC NEW COM NEW 87960W203 1,555 2,500,260 SH   SOLE   2,500,260 0 0
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS 881624209 50,254 4,354,756 SH   SOLE   4,354,756 0 0
TG THERAPEUTICS INC COM 88322Q108 36,757 762,589 SH   SOLE   762,589 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102 81,382 486,529 SH   SOLE   486,529 0 0
ZOGENIX INC COM NEW 98978L204 16,069 823,229 SH   SOLE   823,229 0 0
ACADIA PHARMACEUTICALS INC CALL 004225908 277 250 SH   SOLE   250 0 0
AMARIN CORP PLC CALL 023111906 437 4,408 SH   SOLE   4,408 0 0
ARK ETF TR PUT 00214Q952 2,979 569 SH   SOLE   569 0 0
CENTENE CORP DEL CALL 15135B901 1,549 500 SH   SOLE   500 0 0
FREQUENCY THERAPEUTICS INC PUT 35803L958 1,416 1,936 SH   SOLE   1,936 0 0
GLAXOSMITHKLINE PLC CALL 37733W905 18,292 11,541 SH   SOLE   11,541 0 0
NOVAVAX INC CALL 670002901 1,116 100 SH   SOLE   100 0 0
SPDR S&P 500 ETF TR PUT 78462F953 9,844 1,000 SH   SOLE   1,000 0 0
VERTEX PHARMACEUTICALS INC CALL 92532F900 6,263 600 SH   SOLE   600 0 0