The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
AbbVie Inc. Common 00287Y109 2,139 19,769 SH   DFND 2 19,769 0 0
AbbVie Inc. Common 00287Y109 541 5,000 SH   DFND 1 5,000 0 0
African Gold Acquistion Corp. Common G0112R116 5,928 600,000 SH   DFND 2 600,000 0 0
African Gold Acquistion Corp. Common G0112R116 178 18,000 SH   DFND 1 18,000 0 0
Alerian MLP Common 00162Q452 4 120 SH   DFND 1 120 0 0
Alimera Sciences, Inc. Common 016259202 559 58,108 SH   DFND 2 58,108 0 0
Alphabet Inc-Cl C Common 02079K107 11,584 5,600 SH   DFND 2 5,600 0 0
ALX Oncology Holdings Inc Common 01166B105 236 3,200 SH   DFND 2 3,200 0 0
AllianceBernstein Holdings PL Unit Ltd Common 01881G106 60 1,500 SH   DFND 1 1,500 0 0
AllianceBernstein Holdings PL Unit Ltd Common 01881G106 1,960 49,000 SH   DFND 1 49,000 0 0
Apollo Global Management, Inc. Common 03768E105 14,103 300,000 SH   DFND 2 300,000 0 0
Apple Inc. Common 037833100 257 2,100 SH   DFND 1 2,100 0 0
ASLAN Pharmaceuticals Limited Common 04522R101 1,465 437,412 SH   DFND 2 437,412 0 0
AT&T Inc. Common 00206R102 2 50 SH   DFND 1 50 0 0
AT&T Inc. Common 00206R102 605 20,000 SH   DFND 1 20,000 0 0
Aurinia Pharmaceuticals Inc. Common 05156V102 2,011 154,840 SH   DFND 2 154,840 0 0
Avadel Pharmaceuticals plc Common 05337M104 2,467 272,845 SH   DFND 2 272,845 0 0
Bank Nova Scotia Halifax Common 064149107 25 400 SH   DFND 1 400 0 0
B. Riley Principal 150 Merger Corp. Common 05601V202 1,730 172,963 SH   DFND 2 172,963 0 0
B. Riley Principal 150 Merger Corp. Common 05601V202 30 3,000 SH   DFND 1 3,000 0 0
BioCryst Pharmaceuticals, Inc. Common 09058V103 312 30,703 SH   DFND 2 30,703 0 0
Bristol-Myers Squibb Company Common 110122108 3,245 51,409 SH   DFND 2 51,409 0 0
Brookline Capital Acq Corp. Warrants Common 11374E112 23 2,000 SH   DFND 2 2,000 0 0
Brookline Capital Acquisition Corp. Common 11374E104 39 4,000 SH   DFND 2 4,000 0 0
Butterfly Network, Inc. Common 124155102 309 18,380 SH   DFND 2 18,380 0 0
Calumet Specialty Products Partners, LP Common 131476103 17,080 2,800,000 SH   DFND 2 2,800,000 0 0
Calumet Specialty Products Partners, LP Common 131476103 275 45,000 SH   DFND 1 45,000 0 0
Canadian Natural Resources Inc. Common 136385101 564 18,285 SH   DFND 1 18,285 0 0
Canadian Natural Resources Inc. Common 136385101 123 4,000 SH   DFND 1 4,000 0 0
Capitol Investment Corp. V Common 14064F100 2,525 250,000 SH   DFND 2 250,000 0 0
Capitol Investment Corp. V Warrants Common 14064F118 958 83,333 SH   DFND 2 83,333 0 0
Capitol Federal S&L Common 14057J101 156 5,800 SH   DFND 1 5,800 0 0
Carparts.com Inc. Common 14427M107 53 3,700 SH   DFND 1 3,700 0 0
Cidara Therapeutics, Inc. Common 171757107 1,105 415,308 SH   DFND 2 415,308 0 0
Chemours Co Common 163851108 13 480 SH   DFND 1 480 0 0
Chemours Co Common 163851108 12 440 SH   DFND 1 440 0 0
Coca Cola Common 191216100 306 5,800 SH   DFND 1 5,800 0 0
Coca Cola Common 191216100 401 7,600 SH   DFND 1 7,600 0 0
Coherus Biosciences, Inc. Common 19249H103 1,456 99,655 SH   DFND 2 99,655 0 0
Colony Cap Inc. Common 19626G108 10 1,466 SH   DFND 1 1,466 0 0
Colony Cap Inc. Common 19626G108 71 11,000 SH   DFND 1 11,000 0 0
Conagra Brands Common 205887102 376 10,000 SH   DFND 1 10,000 0 0
Constellation Pharmaceuticals, Inc. Common 210373106 2,009 85,909 SH   DFND 2 85,909 0 0
Corteva Inc. Common 22052L104 46 982 SH   DFND 1 982 0 0
Corteva Inc. Common 22052L104 515 11,051 SH   DFND 1 11,051 0 0
Cousins Properties Common 222795502 119 3,357 SH   DFND 1 3,357 0 0
CTI BioPharma Corp. Common 12648L601 58 20,000 SH   DFND 2 20,000 0 0
Curis, Inc. Common 231269200 113 10,000 SH   DFND 2 10,000 0 0
Danimer Scientific, Inc. Common 236272100 7,550 200,000 SH   DFND 2 200,000 0 0
Dow Inc. Common 260557103 96 1,494 SH   DFND 1 1,494 0 0
Dow Inc. Common 260557103 679 10,624 SH   DFND 1 10,624 0 0
Dupont De Nemours Inc. Common 26614N102 115 1,494 SH   DFND 1 1,494 0 0
Dupont De Nemours Inc. Common 26614N102 821 10,624 SH   DFND 1 10,624 0 0
Eagle Materials Common 26969P108 31 228 SH   DFND 1 228 0 0
Eastern Bankshares Inc Common 27627N105 193 10,000 SH   DFND 1 10,000 0 0
Eastern Bankshares Inc Common 27627N105 3,665 190,000 SH   DFND 2 190,000 0 0
Eiger BioPharmaceuticals, Inc. Common 28249U105 2,447 276,535 SH   DFND 2 276,535 0 0
Eli Lilly Inc. Common 532457108 56 300 SH   DFND 1 300 0 0
FNB Corporation Common 302520101 113 8,905 SH   DFND 1 8,905 0 0
Facebook Inc. Common 30303M102 292 990 SH   DFND 1 990 0 0
Fortress Trans & Infrastructure Inv. LLC Common 34960P101 14,095 500,000 SH   DFND 2 500,000 0 0
FS Bancorp Common 30263Y104 142 2,117 SH   DFND 1 2,117 0 0
FS Bancorp Common 30263Y104 98 1,460 SH   DFND 1 1,460 0 0
FS KKR Capital Corp. Common 302635206 6,941 350,000 SH   DFND 2 350,000 0 0
FS KKR Capital Corp. Common 302635206 318 16,050 SH   DFND 1 16,050 0 0
FS KKR Capital Corp. Common 302635206 578 29,125 SH   DFND 1 29,125 0 0
Full House Resort Inc. Common 359678109 426 50,000 SH   DFND 2 50,000 0 0
Galapagos NV Common 36315X101 77 1,000 SH   DFND 2 1,000 0 0
General Electric Common 369604103 30 2,280 SH   DFND 1 2,280 0 0
General Electric Common 369604103 16 1,200 SH   DFND 1 1,200 0 0
Gilead Sciences, Inc. Common 375558103 3,292 50,942 SH   DFND 2 50,942 0 0
Glass Houses Acquisition Corp. Common 37714P202 5,015 500,000 SH   DFND 2 500,000 0 0
Globus Medical, Inc. Common 379577208 286 4,631 SH   DFND 2 4,631 0 0
HealthCor Catalio Acquisition Corp. Common G44125105 40 4,000 SH   DFND 2 4,000 0 0
Heritage NOLA Bancorp Inc. Common 42727P108 122 9,000 SH   DFND 1 9,000 0 0
Horizon Aquistion Corporation Common G46049105 2,076 210,100 SH   DFND 2 210,100 0 0
Horizon Therapeutics Public Ltd. Company Common G46188101 3,738 40,614 SH   DFND 2 40,614 0 0
Ibere Pharmaceuticals Common G46843127 355 36,000 SH   DFND 2 36,000 0 0
Immunovant Inc. Common 45258J102 547 34,100 SH   DFND 2 34,100 0 0
Independence Holdings Corp Units Common G4761A119 95 9,500 SH   DFND 1 9,500 0 0
International Business Machines Common 459200101 571 4,284 SH   DFND 1 4,284 0 0
International Gaming Technologies Common G4863A108 120 7,500 SH   DFND 1 7,500 0 0
International Gaming Technologies Common G4863A108 1,605 100,000 SH   DFND 2 100,000 0 0
iShares Nasdaq Biotechnology ETF Common 464287556 151 1,000 SH   DFND 2 1,000 0 0
Johnson & Johnson Common 478160104 835 5,080 SH   DFND 1 5,080 0 0
Johnson & Johnson Common 478160104 164 1,000 SH   DFND 1 1,000 0 0
JP Morgan Chase Common 46625H100 1,484 9,750 SH   DFND 1 9,750 0 0
JP Morgan Chase Common 46625H100 871 5,720 SH   DFND 1 5,720 0 0
Jumia Technologies AG Common 48138M105 202 5,700 SH   DFND 1 5,700 0 0
Kadmon Holdings, Inc. Common 48283N106 2,964 762,000 SH   DFND 2 762,000 0 0
Kairos Acquisition Corp. Common G52110114 2,546 261,374 SH   DFND 2 261,374 0 0
Kairos Acquisition Corp Units Common G52110122 145 14,500 SH   DFND 1 14,500 0 0
Kairos Acquisition Corp. Warrants Common G52110106 1,503 130,687 SH   DFND 2 130,687 0 0
Kennedy-Wilson Holdings, Inc. Common 489398107 4,244 210,000 SH   DFND 2 210,000 0 0
Kimberly Clark Corporation Common 494368103 834 6,000 SH   DFND 1 6,000 0 0
KKR & Co. Inc. Common 48251W104 4,885 100,000 SH   DFND 2 100,000 0 0
Legacy Housing Corporation Common 52472M101 89 5,000 SH   DFND 1 5,000 0 0
Legacy Housing Corporation Common 52472M101 71 4,000 SH   DFND 1 4,000 0 0
Ligand Pharmaceuticals Incorporated Common 53220K504 11,434 75,000 SH   DFND 2 75,000 0 0
Live Oak Mobility Aquisition Corp. Common 538126202 3,594 360,152 SH   DFND 2 360,152 0 0
Longview Acquisition Corp II Common 54319Q204 642 63,900 SH   DFND 2 63,900 0 0
Marinus Pharmaceuticals, Inc. Common 56854Q200 933 60,266 SH   DFND 2 60,266 0 0
Macquarie Infrastructure Corporation Common 55608B105 105 3,300 SH   DFND 1 3,300 0 0
Macquarie Infrastructure Corporation Common 55608B105 313 9,850 SH   DFND 1 9,850 0 0
Medicus Science Acquisition, Corp. Common G5960S116 1,970 200,000 SH   DFND 2 200,000 0 0
Merck & Co. Inc. Common 58933Y105 62 800 SH   DFND 1 800 0 0
Merck & Co. Inc. Common 58933Y105 39 500 SH   DFND 1 500 0 0
Medtronics Common G5960L103 124 1,050 SH   DFND 1 1,050 0 0
Microsoft Corporation Common 594918104 94 400 SH   DFND 1 400 0 0
Microsoft Corporation Common 594918104 236 1,000 SH   DFND 1 1,000 0 0
Midwest Holding Inc. Common 59833J206 7,499 150,000 SH   DFND 2 150,000 0 0
Millendo Therapeutics, Inc. Common 60040X103 165 137,900 SH   DFND 2 137,900 0 0
Mondelez Int'l Inc. Common 609207105 170 2,900 SH   DFND 1 2,900 0 0
Mondelez Int'l Inc. Common 609207105 761 13,000 SH   DFND 1 13,000 0 0
Occidental Pete Corp Common 674599105 30 1,114 SH   DFND 1 1,114 0 0
Occidental Pete Corp Wts exp 8/3/27 Common 674599162 5 212 SH   DFND 1 212 0 0
Occidental Pete Corp Common 674599105 34 1,273 SH   DFND 1 1,273 0 0
Occidental Pete Corp Wts exp 8/3/27 Common 674599162 3 158 SH   DFND 1 158 0 0
Peoples United Financial Common 712704105 27 1,500 SH   DFND 1 1,500 0 0
Pfizer Inc. Common 717081103 1,120 30,900 SH   DFND 1 30,900 0 0
Pfizer Inc. Common 717081103 3,224 89,000 SH   DFND 1 89,000 0 0
Poseida Therapeutics, Inc. Common 73730P108 282 29,566 SH   DFND 2 29,566 0 0
Protara Therapeutics, Inc. Common 74365U107 226 14,369 SH   DFND 2 14,369 0 0
Quotient Technology Inc. Common 749119103 817 50,000 SH   DFND 2 50,000 0 0
Relmada Therapeutics, Inc. Common 75955J402 106 3,000 SH   DFND 2 3,000 0 0
Roth CH Acquisition III Co. Common 77867Q201 1,000 100,000 SH   DFND 2 100,000 0 0
RMR Group Inc. Common 74967R106 1 16 SH   DFND 1 16 0 0
Ryman Hospitality Ppty Inc. Common 78377T107 31 400 SH   DFND 1 400 0 0
Ryman Hospitality Ppty Inc. Common 78377T107 930 12,000 SH   DFND 1 12,000 0 0
Sailpoint Technologies Common 78781P105 86 1,700 SH   DFND 1 1,700 0 0
Sculptor Capital Management Common 811246107 4 200 SH   DFND 1 200 0 0
Seelos Therapeutics, Inc. Common 81577F109 361 72,367 SH   DFND 2 72,367 0 0
Service Ppty Trust Common 81761L102 12 1,000 SH   DFND 1 1,000 0 0
Sio Gene Therapies, Inc. Common 829399104 183 70,000 SH   DFND 2 70,000 0 0
South Street Corporation Common 840441109 122 1,548 SH   DFND 1 1,548 0 0
South Street Corporation Common 840441109 42 534 SH   DFND 1 534 0 0
SPDR S&P Biotech ETF Common 78464A870 515 3,800 SH   DFND 2 3,800 0 0
Starwood Ppty Common 85571B105 10 400 SH   DFND 1 400 0 0
TG Therapeutics, Inc. Common 88322Q108 2,505 51,973 SH   DFND 2 51,973 0 0
T-Mobil US Inc. Common 872590104 88 700 SH   DFND 1 700 0 0
Tastemaker Acquisition Corp. Common 876545104 1,948 200,000 SH   DFND 2 200,000 0 0
Tastemaker Acquisition Corp. Warrants Common 876545112 1,150 100,000 SH   DFND 2 100,000 0 0
The Kraft Company Common 500754106 108 2,702 SH   DFND 1 2,702 0 0
The Kraft Company Common 500754106 48 1,199 SH   DFND 1 1,199 0 0
Total SA Common 89151E109 91 1,960 SH   DFND 1 1,960 0 0
Total SA Common 89151E109 23 500 SH   DFND 1 500 0 0
Trillium Therapeutics Inc. Common 89620X506 2,134 198,699 SH   DFND 2 198,699 0 0
Twelve Seas Investment Company II Common 90118T205 4,925 500,000 SH   DFND 2 500,000 0 0
Twelve Seas Investment Company II Common 90118T205 148 15,000 SH   DFND 1 15,000 0 0
uniQure N.V. Common N90064101 1,407 41,766 SH   DFND 2 41,766 0 0
United Therapeutics Corporation Common 91307C102 2,425 14,500 SH   DFND 2 14,500 0 0
Up Fintech Holdings Common 91531W106 244 13,736 SH   DFND 1 13,736 0 0
Upland Software, Inc. Common 91544A109 14,157 300,000 SH   DFND 2 300,000 0 0
Valley National Bancorp Common 919794107 128 9,280 SH   DFND 1 9,280 0 0
Valley National Bancorp Common 919794107 44 3,200 SH   DFND 1 3,200 0 0
Verizon Communications Common 92343V104 42 720 SH   DFND 1 720 0 0
Verizon Communications Common 92343V104 988 16,991 SH   DFND 1 16,991 0 0
Verrica Pharmaceuticals, Inc. Common 92511W108 1,188 78,424 SH   DFND 2 78,424 0 0
Viatris Inc. Common 92556V106 3 248 SH   DFND 1 248 0 0
Viking Therapeutics, Inc. Common 92686J106 1,316 208,102 SH   DFND 2 208,102 0 0
WABTEC Common 929740108 1 11 SH   DFND 1 11 0 0
WABTEC Common 929740108 0 6 SH   DFND 1 6 0 0
WP Carey Common 92936U109 425 6,000 SH   DFND 1 6,000 0 0
Warrior Technologies Acquisition Company Common 936273200 248 25,000 SH   DFND 2 25,000 0 0
Xenon Pharmaceuticals Inc. Common 98420N105 2,579 144,101 SH   DFND 2 144,101 0 0
Zogenix, Inc. Common 98978L204 2,297 117,688 SH   DFND 2 117,688 0 0