The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
3M CO COM 88579Y101 3,595 18,659 SH   DFND 1 0 18,659 0
3M CO COM 88579Y101 238 1,225 SH   DFND 3 0 1,225 0
ABBOTT LABS COM 002824100 3,719 31,060 SH   DFND 3 0 31,060 0
ABBVIE INC COM 00287Y109 214 2,000 SH   DFND 3 0 2,000 0
ACCENTURE PLC IRELAND SHS CLASS A G1151C101 2,171 7,793 SH   DFND 3 0 7,793 0
ADOBE SYSTEMS INCORPORATED COM 00724F101 1,943 4,088 SH   DFND 1 0 4,088 0
ADOBE SYSTEMS INCORPORATED COM 00724F101 293 630 SH   DFND 3 0 630 0
AGILENT TECHNOLOGIES INC COM 00846U101 1,186 9,500 SH   DFND 3 0 9,500 0
AKAMAI TECHNOLOGIES INC COM 00971T101 3,936 38,900 SH   DFND 3 0 38,900 0
ALAMO GROUP INC COM 011311107 341 2,200 SH   DFND 3 0 2,200 0
ALGONQUIN PWR UTILS CORP COM 015857105 2,248 89,960 SH   DFND 3 0 89,960 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 4,292 18,720 SH   DFND 3 0 18,720 0
ALPHABET INC CAP STK CL A 02079K305 206 100 SH   DFND   0 100 0
ALPHABET INC CAP STK CL C 02079K107 4,181 2,021 SH   DFND 1 0 2,021 0
ALPHABET INC CAP STK CL A 02079K305 7,375 3,604 SH   DFND 3 0 3,604 0
ALPHABET INC CAP STK CL C 02079K107 691 336 SH   DFND 3 0 336 0
ALTRIA GROUP INC COM 02209S103 256 5,000 SH   DFND 3 0 5,000 0
AMAZON COM INC COM 023135106 5,198 1,700 SH   DFND 3 0 1,700 0
AMERICAN TOWER CORP NEW COM 03027X100 745 3,141 SH   DFND 3 0 3,141 0
AMERICAN WELL CORP CL A 03044L105 35,274 2,030,767 SH   DFND   0 2,030,767 0
AMGEN INC COM 031162100 281 1,125 SH   DFND 3 0 1,125 0
AMNEAL PHARMACEUTICALS INC COM STK CL A 03168L105 123,884 18,407,656 SH   DFND   0 18,407,656 0
AMNEAL PHARMACEUTICALS INC COM STK CL A 03168L105 20,955 3,113,645 SH   DFND 2 0 3,113,645 0
AMPHENOL CORP NEW CL A 032095101 1,102 16,800 SH   DFND 3 0 16,800 0
ANGLOGOLD ASHANTI LIMITED SPONSORED ADR 035128206 433 20,000 SH   DFND 3 0 20,000 0
AON PLC SHS CL A G0403H108 395 1,700 SH   DFND 3 0 1,700 0
APPLE INC COM 037833100 3,779 30,939 SH   DFND 1 0 30,939 0
APPLE INC COM 037833100 2,062 17,200 SH   DFND 3 0 17,200 0
ARES CAPITAL CORP COM 04010L103 3,840 203,707 SH   DFND 3 0 203,707 0
BALL CORP COM 058498106 877 10,375 SH   DFND 3 0 10,375 0
BARRICK GOLD CORP COM 067901108 3,931 133,780 SH   DFND 3 0 133,780 0
BERKSHIRE HATHAWAY INC DEL CL A 084670108 1,561 4 SH   DFND 3 0 4 0
BERKSHIRE HATHAWAY INC DEL CL B NEW 084670702 6,163 23,870 SH   DFND 3 0 23,870 0
BEST INC SPONSORED ADS 08653C106 12,318 6,552,117 SH   DFND   0 6,552,117 0
BILIBILI INC SPONS ADS REP Z 090040106 956 8,931 SH   DFND 4 0 8,931 0
BLACKROCK INC COM 09247X101 1,799 2,401 SH   DFND 3 0 2,401 0
BOOKING HOLDINGS INC COM 09857L108 1,471 630 SH   DFND 3 0 630 0
BOSTON BEER INC CL A 100557107 1,076 900 SH   DFND 3 0 900 0
BOSTON SCIENTIFIC CORP COM 101137107 857 21,985 SH   DFND 3 0 21,985 0
BP PLC SPONSORED ADR 055622104 4,570 187,684 SH   DFND 4 0 187,684 0
BROOKFIELD RENEWABLE PARTNER PARTNERSHIP UNIT G16258108 11,908 175,200 SH   DFND 3 0 175,200 0
BURLINGTON STORES INC COM 122017106 646 2,120 SH   DFND 3 0 2,120 0
BUTTERFLY NETWORK INC COM CL A 124155102 180,361 10,716,630 SH   DFND 2 0 10,716,630 0
CARRIAGE SVCS INC COM 143905107 246 7,000 SH   DFND 3 0 7,000 0
CATERPILLAR INC COM 149123101 612 2,625 SH   DFND 3 0 2,625 0
CENTENE CORP DEL COM 15135B101 5,230 80,000 SH   DFND 3 0 80,000 0
CHECK CAP LTD SHS M2361E203 225 127,559 SH   DFND 2 0 127,559 0
CHECK POINT SOFTWARE TECH LT ORD M22465104 384 3,360 SH   DFND 3 0 3,360 0
CHENIERE ENERGY INC COM NEW 16411R208 397 5,500 SH   DFND 3 0 5,500 0
CHINA INDEX HLDGS LTD SPNSRD ADS A 16954W101 3,549 1,613,208 SH   DFND 1 0 1,613,208 0
CHINA LIFE INS CO LTD SPON ADR REP H 16939P106 4,482 430,576 SH   DFND 4 0 430,576 0
CHUBB LIMITED COM H1467J104 209 1,295 SH   DFND 3 0 1,295 0
CINTAS CORP COM 172908105 4,284 12,700 SH   DFND 3 0 12,700 0
CISCO SYS INC COM 17275R102 1,201 23,200 SH   DFND 3 0 23,200 0
COCA COLA CO COM 191216100 3,686 69,921 SH   DFND 1 0 69,921 0
COCA COLA CO COM 191216100 529 10,000 SH   DFND 3 0 10,000 0
COGNIZANT TECHNOLOGY SOLUTIO CL A 192446102 4,321 55,000 SH   DFND 3 0 55,000 0
COLGATE PALMOLIVE CO COM 194162103 646 8,170 SH   DFND 3 0 8,170 0
COLONY CAP INC NOTE 5.000% 4/1 19624RAA4 16,253 16,000,000 SH   DFND 1 0 16,000,000 0
COMPUTER TASK GROUP INC COM 205477102 683 71,546 SH   DFND 3 0 71,546 0
CONTRAFECT CORP COM NEW 212326300 3,578 745,385 SH   DFND 2 0 745,385 0
CUMMINS INC COM 231021106 922 3,500 SH   DFND 3 0 3,500 0
CUREVAC N V COM N2451R105 4,438 50,000 SH   DFND 3 0 50,000 0
CYMABAY THERAPEUTICS INC COM 23257D103 840 185,000 SH   DFND   0 185,000 0
CYMABAY THERAPEUTICS INC COM 23257D103 357 78,529 SH   DFND 4 0 78,529 0
DANAHER CORPORATION COM 235851102 5,620 25,200 SH   DFND 3 0 25,200 0
DECKERS OUTDOOR CORP COM 243537107 1,172 3,600 SH   DFND 3 0 3,600 0
DEUTSCHE BANK A G NAMEN AKT D18190898 5,798 480,000 SH   DFND 3 0 480,000 0
DISNEY WALT CO COM 254687106 540 2,924 SH   DFND 1 0 2,924 0
DISNEY WALT CO COM 254687106 911 4,910 SH   DFND 3 0 4,910 0
EDAP TMS S A SPONSORED ADR 268311107 1,001 103,906 SH   DFND 3 0 103,906 0
ELANCO ANIMAL HEALTH INC COM 28414H103 495 17,180 SH   DFND 3 0 17,180 0
ELECTRONIC ARTS INC COM 285512109 202 1,505 SH   DFND 3 0 1,505 0
EPAM SYS INC COM 29414B104 384 1,000 SH   DFND 3 0 1,000 0
EQUINIX INC COM 29444U700 270 400 SH   DFND 3 0 400 0
EXXON MOBIL CORP COM 30231G102 4,056 72,645 SH   DFND 1 0 72,645 0
EZCORP INC CL A NON VTG 302301106 61 12,000 SH   DFND 3 0 12,000 0
FACEBOOK INC CL A 30303M102 3,704 12,860 SH   DFND 3 0 12,860 0
FANG HLDGS LTD ADR NEW 30711Y300 3,472 277,734 SH   DFND 1 0 277,734 0
FANG HLDGS LTD ADR NEW 30711Y300 636 50,886 SH   DFND   0 50,886 0
FIDELITY NATL INFORMATION SV COM 31620M106 741 5,198 SH   DFND 3 0 5,198 0
FISERV INC COM 337738108 1,449 12,174 SH   DFND 1 0 12,174 0
FOOT LOCKER INC COM 344849104 561 9,790 SH   DFND 3 0 9,790 0
FRANCO NEV CORP COM 351858105 2,483 12,575 SH   DFND 3 0 12,575 0
FRESHPET INC COM 358039105 280 1,800 SH   DFND 3 0 1,800 0
FTI CONSULTING INC COM 302941109 421 3,000 SH   DFND 3 0 3,000 0
GARMIN LTD SHS H2906T109 4,445 34,000 SH   DFND 3 0 34,000 0
GILEAD SCIENCES INC COM 375558103 2,139 33,098 SH   DFND 4 0 33,098 0
GILEAD SCIENCES INC COM 375558103 5,220 79,700 SH   DFND 3 0 79,700 0
GOLD RESOURCE CORP COM 38068T105 998 390,000 SH   DFND 3 0 390,000 0
GRAND CANYON ED INC COM 38526M106 411 3,800 SH   DFND 3 0 3,800 0
HDFC BANK LTD SPONSORED ADS 40415F101 1,840 22,750 SH   DFND 3 0 22,750 0
HOME DEPOT INC COM 437076102 448 1,470 SH   DFND 3 0 1,470 0
HONEYWELL INTL INC COM 438516106 846 3,878 SH   DFND 3 0 3,878 0
HUAZHU GROUP LTD SPONSORED ADS 44332N106 3,681 66,900 SH   DFND   0 66,900 0
IAMGOLD CORP COM 450913108 288 100,000 SH   DFND 3 0 100,000 0
ICF INTL INC COM 44925C103 433 4,900 SH   DFND 3 0 4,900 0
ILLUMINA INC COM 452327109 4,796 13,000 SH   DFND 3 0 13,000 0
INTEL CORP COM 458140100 4,039 63,107 SH   DFND 1 0 63,107 0
INTEL CORP COM 458140100 411 6,445 SH   DFND 3 0 6,445 0
INTERNATIONAL BUSINESS MACHS COM 459200101 539 4,000 SH   DFND 3 0 4,000 0
INTERNATIONAL FLAVORS&FRAGRA COM 459506101 6,988 50,000 SH   DFND 3 0 50,000 0
INTUIT COM 461202103 2,156 5,771 SH   DFND 3 0 5,771 0
INTUITIVE SURGICAL INC COM NEW 46120E602 4,432 6,100 SH   DFND 3 0 6,100 0
IONIS PHARMACEUTICALS INC NOTE 0.125%12/1 462222AB6 381 400,000 SH   DFND 3 0 400,000 0
IROBOT CORP COM 462726100 490 4,200 SH   DFND 3 0 4,200 0
ISHARES TR MSCI EMG MKT ETF 464287234 221 4,145 SH   DFND 1 0 4,145 0
JD. COM INC SPON ADR CL A 47215P106 398 4,800 SH   DFND 3 0 4,800 0
JOHNSON & JOHNSON COM 478160104 3,745 22,786 SH   DFND 1 0 22,786 0
JOHNSON & JOHNSON COM 478160104 3,067 18,585 SH   DFND 3 0 18,585 0
JPMORGAN CHASE & CO COM 46625H100 513 3,320 SH   DFND 3 0 3,320 0
KILROY RLTY CORP COM 49427F108 209 3,100 SH   DFND 3 0 3,100 0
KRAFT HEINZ CO COM 500754106 403 10,000 SH   DFND 3 0 10,000 0
LAKELAND INDS INC COM 511795106 219 8,100 SH   DFND 3 0 8,100 0
LAM RESEARCH CORP COM 512807108 7,042 12,300 SH   DFND 3 0 12,300 0
LAUDER ESTEE COS INC CL A 518439104 325 1,100 SH   DFND 3 0 1,100 0
LIGAND PHARMACEUTICALS INC COM NEW 53220K504 447 3,000 SH   DFND 3 0 3,000 0
LILLY ELI & CO COM 532457108 308 1,660 SH   DFND 3 0 1,660 0
LINDE PLC SHS G5494J103 4,039 14,440 SH   DFND 3 0 14,440 0
LKQ CORP COM 501889208 3,643 85,000 SH   DFND 3 0 85,000 0
LOGITECH INTL S A SHS H50430232 1,370 15,000 SH   DFND 3 0 15,000 0
LULULEMON ATHLETICA INC COM 550021109 476 1,500 SH   DFND 3 0 1,500 0
MADDEN STEVEN LTD COM 556269108 308 8,250 SH   DFND 3 0 8,250 0
MAKEMYTRIP LIMITED MAURITIUS SHS V5633W109 479 15,172 SH   DFND 4 0 15,172 0
MANHATTAN ASSOCIATES INC COM 562750109 469 4,000 SH   DFND 3 0 4,000 0
MARSH & MCLENNAN COS INC COM 571748102 548 4,507 SH   DFND 3 0 4,507 0
MARTIN MARIETTA MATLS INC COM 573284106 371 1,080 SH   DFND 3 0 1,080 0
MASIMO CORP COM 574795100 791 3,500 SH   DFND 3 0 3,500 0
MASTERCARD INCORPORATED CL A 57636Q104 4,366 12,190 SH   DFND 3 0 12,190 0
MCDONALDS CORP COM 580135101 2,385 10,600 SH   DFND 3 0 10,600 0
MEDTRONIC PLC SHS G5960L103 1,378 11,600 SH   DFND 3 0 11,600 0
MERCADOLIBRE INC COM 58733R102 2,470 1,730 SH   DFND 3 0 1,730 0
MERCK & CO. INC COM 58933Y105 8,982 116,518 SH   DFND 4 0 116,518 0
MERCK & CO. INC COM 58933Y105 3,893 50,500 SH   DFND   0 50,500 0
MERCK & CO. INC COM 58933Y105 1,613 20,920 SH   DFND 1 0 20,920 0
MERCK & CO. INC COM 58933Y105 438 5,695 SH   DFND 3 0 5,695 0
MICROSOFT CORP COM 594918104 2,851 12,093 SH   DFND 1 0 12,093 0
MICROSOFT CORP COM 594918104 8,409 36,250 SH   DFND 3 0 36,250 0
MOMO INC NOTE 1.250% 7/0 60879BAB3 26,791 30,523,000 SH   DFND 1 0 30,523,000 0
NATURES SUNSHINE PRODS INC COM 639027101 57,759 2,893,732 SH   DFND 2 0 2,893,732 0
NETEASE INC SPONSORED ADS 64110W102 463 4,500 SH   DFND 3 0 4,500 0
NEW FRONTIER HEALTH CORP ORD SHS G6461G106 106,220 9,400,000 SH   DFND 2 0 9,400,000 0
NEXTERA ENERGY INC COM 65339F101 570 7,680 SH   DFND 3 0 7,680 0
NIKE INC CL B 654106103 3,272 24,622 SH   DFND 1 0 24,622 0
NIKE INC CL B 654106103 825 6,204 SH   DFND 3 0 6,204 0
NORFOLK SOUTHN CORP COM 655844108 2,043 7,560 SH   DFND 3 0 7,560 0
NORTHERN TR CORP COM 665859104 561 5,242 SH   DFND 3 0 5,242 0
NUTRIEN LTD COM 67077M108 348 4,000 SH   DFND 3 0 4,000 0
NVIDIA CORPORATION COM 67066G104 7,065 13,722 SH   DFND 3 0 13,722 0
OMEGA FLEX INC COM 682095104 321 2,000 SH   DFND 3 0 2,000 0
ONCORUS INC COM 68236R103 13,396 962,321 SH   DFND 2 0 962,321 0
ORACLE CORP COM 68389X105 3,591 51,178 SH   DFND 1 0 51,178 0
ORACLE CORP COM 68389X105 331 4,695 SH   DFND 3 0 4,695 0
PAYPAL HLDGS INC COM 70450Y103 9,293 39,270 SH   DFND 3 0 39,270 0
PEPSICO INC COM 713448108 356 2,500 SH   DFND 3 0 2,500 0
PFIZER INC COM 717081103 9,471 261,413 SH   DFND 4 0 261,413 0
PFIZER INC COM 717081103 5,044 139,219 SH   DFND 1 0 139,219 0
PFIZER INC COM 717081103 4,057 112,000 SH   DFND   0 112,000 0
PFIZER INC COM 717081103 351 9,720 SH   DFND 3 0 9,720 0
PHILIP MORRIS INTL INC COM 718172109 2,879 32,220 SH   DFND 3 0 32,220 0
PROCTER AND GAMBLE CO COM 742718109 3,451 25,481 SH   DFND 1 0 25,481 0
PROCTER AND GAMBLE CO COM 742718109 1,494 11,031 SH   DFND 3 0 11,031 0
QORVO INC COM 74736K101 775 4,361 SH   DFND 3 0 4,361 0
RENEWABLE ENERGY GROUP INC COM NEW 75972A301 524 8,000 SH   DFND 3 0 8,000 0
REPLIGEN CORP NOTE 0.375% 7/1 759916AB5 172 100,000 SH   DFND 3 0 100,000 0
REVANCE THERAPEUTICS INC COM 761330109 6,536 233,841 SH   DFND 1 0 233,841 0
S&P GLOBAL INC COM 78409V104 600 1,702 SH   DFND 3 0 1,702 0
SALESFORCE COM INC COM 79466L302 3,150 15,000 SH   DFND 3 0 15,000 0
SCHLUMBERGER LTD COM 806857108 272 10,000 SH   DFND 3 0 10,000 0
SCHWAB CHARLES CORP COM 808513105 1,839 28,400 SH   DFND 3 0 28,400 0
SERVICENOW INC COM 81762P102 887 1,820 SH   DFND 3 0 1,820 0
SHOPIFY INC CL A 82509L107 703 670 SH   DFND 3 0 670 0
SKYWORKS SOLUTIONS INC COM 83088M102 7,140 40,000 SH   DFND 3 0 40,000 0
SOCIEDAD QUIMICA Y MINERA DE SPON ADR SER B 833635105 1,335 25,000 SH   DFND 3 0 25,000 0
SOUTHWEST GAS HLDGS INC COM 844895102 212 3,070 SH   DFND 3 0 3,070 0
SPDR S&P 500 ETF TR TR UNIT 78462F103 3,710 9,362 SH   DFND 4 0 9,362 0
SPIRIT RLTY CAP INC NEW NOTE 3.750% 5/1 84860WAB8 30,433 30,000,000 SH   DFND 1 0 30,000,000 0
SPIRIT RLTY CAP INC NEW NOTE 3.750% 5/1 84860WAB8 10,136 9,992,000 SH   DFND   0 9,992,000 0
SPIRIT RLTY CAP INC NEW NOTE 3.750% 5/1 84860WAB8 9,212 9,000,000 SH   DFND 4 0 9,000,000 0
STAMPS COM INC COM NEW 852857200 464 2,400 SH   DFND 3 0 2,400 0
STRYKER CORPORATION COM 863667101 384 1,580 SH   DFND 3 0 1,580 0
TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADS 874039100 8,192 69,257 SH   DFND 4 0 69,257 0
TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADS 874039100 1,916 16,200 SH   DFND   0 16,200 0
TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADS 874039100 7,181 62,404 SH   DFND 3 0 62,404 0
TAL EDUCATION GROUP SPONSORED ADS 874080104 3,204 59,500 SH   DFND 4 0 59,500 0
TAL EDUCATION GROUP SPONSORED ADS 874080104 2,475 46,000 SH   DFND   0 46,000 0
TELADOC HEALTH INC COM 87918A105 612 3,500 SH   DFND 3 0 3,500 0
THOR INDS INC COM 885160101 1,033 7,610 SH   DFND 3 0 7,610 0
TJX COS INC NEW COM 872540109 230 3,460 SH   DFND 3 0 3,460 0
TRANSUNION COM 89400J107 278 3,100 SH   DFND 3 0 3,100 0
TRIP COM GROUP LTD ADS 89677Q107 8,540 215,887 SH   DFND   0 215,887 0
TRIP COM GROUP LTD ADS 89677Q107 3,897 98,344 SH   DFND 4 0 98,344 0
TRUPANION INC COM 898202106 1,618 21,700 SH   DFND 3 0 21,700 0
UBS GROUP AG SHS H42097107 1,032 74,490 SH   DFND 3 0 74,490 0
ULTA BEAUTY INC COM 90384S303 1,417 4,600 SH   DFND 3 0 4,600 0
UNION PAC CORP COM 907818108 3,977 17,985 SH   DFND 3 0 17,985 0
UNITED PARCEL SERVICE INC CL B 911312106 3,104 18,259 SH   DFND 1 0 18,259 0
UNITEDHEALTH GROUP INC COM 91324P102 1,410 3,775 SH   DFND 3 0 3,775 0
VANECK VECTORS ETF TR FALLEN ANGEL HG 92189F437 147 459,668 SH   DFND 1 0 459,668 0
VANGUARD INDEX FDS S&P 500 ETF SHS 922908363 4,305 11,818 SH   DFND 4 0 11,818 0
VERIZON COMMUNICATIONS INC COM 92343V104 242 4,130 SH   DFND 3 0 4,130 0
VERRICA PHARMACEUTICALS INC COM 92511W108 2,324 153,395 SH   DFND   0 153,395 0
VERRICA PHARMACEUTICALS INC COM 92511W108 1,955 129,013 SH   DFND 4 0 129,013 0
VIACOMCBS INC CL B 92556H206 868 19,243 SH   DFND 1 0 19,243 0
VIATRIS INC COM 92556V106 243 17,392 SH   DFND 4 0 17,392 0
VIEWRAY INC COM 92672L107 103,615 23,819,500 SH   DFND   0 23,819,500 0
VISA INC COM CL A 92826C839 3,633 17,157 SH   DFND 1 0 17,157 0
VISA INC COM CL A 92826C839 3,293 15,540 SH   DFND 3 0 15,540 0
WASTE MGMT INC DEL COM 94106L109 781 6,040 SH   DFND 3 0 6,040 0
WEIBO CORP NOTE 1.250% 11/1 948596AC5 80,972 82,730,000 SH   DFND 1 0 82,730,000 0
WEIBO CORP NOTE 1.250% 11/1 948596AC5 978 1,000,000 SH   DFND   0 1,000,000 0
WHEATON PRECIOUS METALS CORP COM 962879102 6,265 104,200 SH   DFND 3 0 104,200 0
ZIX CORP COM 98974P100 217 30,000 SH   DFND 3 0 30,000 0
ZOETIS INC CL A 98978V103 6,282 40,000 SH   DFND 3 0 40,000 0