The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
21VIANET GROUP INC SPONSORED ADS A 90138A103 92,521 2,667,080 SH   DFND 9,27 2,667,080 0 0
AC IMMUNE SA SHS H00263105 13,515 2,614,095 SH   DFND 14,26,31 2,614,095 0 0
ADOBE SYSTEMS INCORPORATED COM 00724F101 14,384 28,762 SH   DFND 1,22,25 28,762 0 0
AIRBNB INC COM CL A 009066101 14,680 100,000 SH   DFND 1,22,25 100,000 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 2,807,035 12,061,337 SH   DFND 1,7,22,23,25 12,061,337 0 0
AMAZON COM INC COM 023135106 293,599 90,146 SH   DFND 1,10,22,25 90,146 0 0
ASLAN PHARMACEUTICALS LTD ADS 04522R101 3,071 1,678,075 SH   DFND 1,14,22,25,26,31 1,678,075 0 0
BEAM THERAPEUTICS INC COM 07373V105 273,873 3,354,641 SH   DFND 14,26,29 3,354,641 0 0
BEIGENE LTD SPONSORED ADR 07725L102 684,635 2,649,619 SH   DFND 14,26,31 2,649,619 0 0
BILL COM HLDGS INC COM 090043100 758,401 5,556,050 SH   DFND 14,16,20 5,556,050 0 0
BIONTECH SE SPONSORED ADS 09075V102 43,828 537,634 SH   DFND 2,8,27 537,634 0 0
BLACKROCK INC COM 09247X101 4,294,880 5,952,380 SH   DFND 1,9,22,25,27 5,952,380 0 0
BOSTON SCIENTIFIC CORP COM 101137107 8,360 232,545 SH   DFND 1,22,25 232,545 0 0
CHENIERE ENERGY INC DEBT 4.875% 5/2 U16344AB6 269,738 268,209,445 PRN   DFND 3,7,22,25 268,209,445 0 0
CHINA BIOLOGIC PRODS HLDGS I COM G21515104 146,456 1,240,000 SH   DFND 14,26,31 1,240,000 0 0
COHERUS BIOSCIENCES INC COM 19249H103 128,284 7,381,116 SH   DFND 14,26,31 7,381,116 0 0
CONTEXTLOGIC INC COM CL A 21077C107 489,468 26,834,880 SH   DFND 21,22,25 26,834,880 0 0
CORTEVA INC COM 22052L104 72,537 1,873,363 SH   DFND 10,25 1,873,363 0 0
DATADOG INC CL A COM 23804L103 9,192 93,373 SH   DFND 13,15 93,373 0 0
DELL TECHNOLOGIES INC CL C 24703L202 648,481 8,848,147 SH   DFND 19,27,30 8,848,147 0 0
DENALI THERAPEUTICS INC COM 24823R105 369,420 4,410,457 SH   DFND 14,26,29,31 4,410,457 0 0
DOORDASH INC CL A 25809K105 867,635 6,078,005 SH   DFND 1,6,22,25,27,28 6,078,005 0 0
DUCK CREEK TECHNOLOGIES INC SHS 264120106 226,955 5,241,451 SH   DFND 4,13 5,241,451 0 0
EROS STX GLOBAL CORPORATION SHS NEW G3788M114 5,015 2,755,310 SH   DFND 7,22,25 2,755,310 0 0
EVOQUA WATER TECHNOLOGIES CO COM 30057T105 162,897 6,037,705 SH   DFND 13,15 6,037,705 0 0
FARFETCH LTD ORD SH CL A 30744W107 90,588 1,419,654 SH   DFND 21,22,25 1,419,654 0 0
FTS INTERNATIONAL INC COM NEW CL A 30283W302 9,529 496,289 SH   DFND 13 496,289 0 0
GLOBAL PMTS INC COM 37940X102 188,746 876,176 SH   DFND 14,17 876,176 0 0
GRACE W R & CO DEL NEW COM 38388F108 119,919 2,187,501 SH   DFND 10,25 2,187,501 0 0
GUARDANT HEALTH INC COM 40131M109 207,884 1,613,007 SH   DFND 14,26,29 1,613,007 0 0
HDFC BANK LTD SPONSORED ADS 40415F101 352,248 4,874,732 SH   DFND 1,10,22,25 4,874,732 0 0
HOMOLOGY MEDICINES INC COM 438083107 36,357 3,220,293 SH   DFND 14,26,29,31 3,220,293 0 0
ICICI BANK LIMITED ADR 45104G104 337,830 22,734,192 SH   DFND 1,5,10,14,22,25 22,734,192 0 0
IHS MARKIT LTD SHS G47567105 903,678 10,059,869 SH   DFND 9,27 10,059,869 0 0
ILLUMINA INC COM 452327109 20,517 55,452 SH   DFND 1,22,25 55,452 0 0
INTELLIA THERAPEUTICS INC COM 45826J105 43,005 790,527 SH   DFND 10,14,25,26,29 790,527 0 0
ISHARES GOLD TRUST ISHARES 464285105 86,139 4,751,160 SH   DFND 1,22,25 4,751,160 0 0
ISHARES INC MSCI STH KOR ETF 464286772 35,866 416,800 SH   DFND 1,22,25 416,800 0 0
ISHARES INC MSCI TAIWAN ETF 46434G772 43,027 810,600 SH   DFND 1,22,25 810,600 0 0
ISHARES INC MSCI BRAZIL ETF 464286400 43,554 1,174,900 SH   DFND 1,22,25 1,174,900 0 0
ISHARES TR RUSSELL 2000 ETF 464287655 44,310 226,000 SH   DFND 1,22,25 226,000 0 0
KEURIG DR PEPPER INC COM 49271V100 34,782 1,086,926 SH   DFND 13,15 1,086,926 0 0
KKR REAL ESTATE FIN TR INC COM 48251K100 43,707 2,439,024 SH   DFND 1,22,25 2,439,024 0 0
LUMEN TECHNOLOGIES INC COM 156700106 948,279 97,259,407 SH   DFND 1,2,8,11,22,25,27 97,259,407 0 0
MASTERCARD INCORPORATED CL A 57636Q104 856,225 2,398,792 SH   DFND 1,14,17,22,25 2,398,792 0 0
MEDTRONIC PLC SHS G5960L103 9,950 84,938 SH   DFND 1,22,25 84,938 0 0
MICROSOFT CORP COM 594918104 78,774 354,167 SH   DFND 1,22,25 354,167 0 0
ORCHARD THERAPEUTICS PLC ADS 68570P101 4,320 1,000,000 SH   DFND 14,26,31 1,000,000 0 0
PAYPAL HLDGS INC COM 70450Y103 2,225,552 9,502,785 SH   DFND 1,7,14,17,22,24,25 9,502,785 0 0
SALESFORCE COM INC COM 79466L302 24,942 112,082 SH   DFND 1,22,25 112,082 0 0
SCHWAB STRATEGIC TR US TIPS ETF 808524870 85,137 1,371,400 SH   DFND 1,22,25 1,371,400 0 0
SEA LTD SPONSORD ADS 81141R100 183,253 920,639 SH   DFND 1,10,22,25 920,639 0 0
SELECT SECTOR SPDR TR SBI MATERIALS 81369Y100 114,404 1,580,380 SH   DFND 1,22,25 1,580,380 0 0
SELECT SECTOR SPDR TR SBI CONS DISCR 81369Y407 17,138 106,595 SH   DFND 1,22,25 106,595 0 0
SELECT SECTOR SPDR TR SBI INT-INDS 81369Y704 112,709 1,272,830 SH   DFND 1,22,25 1,272,830 0 0
SNOWFLAKE INC CL A 833445109 225,686 802,012 SH   DFND 1,10,22,25 802,012 0 0
SQZ BIOTECHNOLOGIES CO COM 78472W104 72,854 2,513,924 SH   DFND 14,26,31 2,513,924 0 0
STARBUCKS CORP COM 855244109 57,484 537,333 SH   DFND 10,25 537,333 0 0
STRYKER CORPORATION COM 863667101 10,178 41,536 SH   DFND 1,22,25 41,536 0 0
TAL EDUCATION GROUP SPONSORED ADS 874080104 12,998 181,765 SH   DFND 12 181,765 0 0
TENCENT MUSIC ENTMT GROUP SPON ADS 88034P109 218 11,313 SH   DFND 13,15 11,313 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102 700,108 1,503,087 SH   DFND 5,14,18 1,503,087 0 0
UBER TECHNOLOGIES INC COM 90353T100 1,706 33,455 SH   DFND 13,15 33,455 0 0
VIELA BIO INC COM 926613100 146,410 4,070,330 SH   DFND 14,26,29,31 4,070,330 0 0
VIR BIOTECHNOLOGY INC COM 92764N102 147,290 5,499,999 SH   DFND 14,26,29,31 5,499,999 0 0
VIRTU FINL INC CL A 928254101 286,447 11,380,503 SH   DFND 1,13,15,22,25 11,380,503 0 0
VISA INC COM CL A 92826C839 1,157,155 5,290,336 SH   DFND 1,14,17,22,25 5,290,336 0 0
VMWARE INC CL A COM 928563402 94,623 674,623 SH   DFND 10,25 674,623 0 0
ZIMMER BIOMET HOLDINGS INC COM 98956P102 9,813 63,685 SH   DFND 1,22,25 63,685 0 0
ZOOM VIDEO COMMUNICATIONS IN CL A 98980L101 1,272 3,772 SH   DFND 13,15 3,772 0 0
ZTO EXPRESS CAYMAN INC SPONSORED ADS A 98980A105 355,074 12,176,750 SH   DFND 1,22,25 12,176,750 0 0