The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
89BIO INC COM 282559103 1,072 44,007 SH   SOLE   44,007 0 0
ACTINIUM PHARMACEUTICALS INC COM 00507W206 702 90,000 SH   SOLE   90,000 0 0
ADAMAS PHARMACEUTICALS INC COM 00548A106 1,909 440,955 SH   SOLE   440,955 0 0
AFFIMED N V COM N01045108 2,328 400,000 SH   SOLE   400,000 0 0
AKERO THERAPEUTICS INC COM 00973Y108 908 35,179 SH   SOLE   35,179 0 0
ALEXION PHARMACEUTICALS INC COM 015351109 781 5,000 SH   SOLE   5,000 0 0
AMRYT PHARMA PLC SPONSORED ADS 03217L106 5,700 402,556 SH   SOLE   402,556 0 0
APTINYX INC COM 03836N103 372 107,536 SH   SOLE   107,536 0 0
ARCUTIS BIOTHERAPEUTICS INC COM 03969K108 239 8,505 SH   SOLE   8,505 0 0
ARDELYX INC COM 039697107 776 120,000 SH   SOLE   120,000 0 0
ARENA PHARMACEUTICALS INC COM NEW 040047607 1,537 20,000 SH   SOLE   20,000 0 0
ARVINAS INC COM 04335A105 4,671 55,000 SH   SOLE   55,000 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101 2,928 17,556 SH   SOLE   17,556 0 0
BIOCRYST PHARMACEUTICALS INC COM 09058V103 820 110,000 SH   SOLE   110,000 0 0
BIOGEN INC CALL 09062X903 7,346 30,000 SH Call SOLE   30,000 0 0
BIOGEN INC COM 09062X103 735 3,000 SH   SOLE   3,000 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 1,414 16,500 SH   SOLE   16,500 0 0
BIOMX INC COM 09090D103 88 13,759 SH   SOLE   13,759 0 0
BIONANO GENOMICS INC *W EXP 08/21/202 09075F115 21 10,000 SH   SOLE   10,000 0 0
CALITHERA BIOSCIENCES INC COM 13089P101 74 15,000 SH   SOLE   15,000 0 0
CALITHERA BIOSCIENCES INC CALL 13089P901 491 100,000 SH Call SOLE   100,000 0 0
CALITHERA BIOSCIENCES INC CALL 13089P901 246 50,000 SH Call SOLE   50,000 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 1,407 80,282 SH   SOLE   80,282 0 0
CELLECTAR BIOSCIENCES INC COM PAR 15117F500 3,688 1,772,848 SH   SOLE   1,772,848 0 0
CHARDAN HEALTHCR ACQSTN 2 CO *W EXP 03/05/202 15957T115 49 98,756 SH   SOLE   98,756 0 0
CHEMOCENTRYX INC COM 16383L106 3,329 53,766 SH   SOLE   53,766 0 0
COGENT BIOSCIENCES INC COM 19240Q201 2,640 235,066 SH   SOLE   235,066 0 0
COMPUGEN LTD CALL M25722905 242 20,000 SH Call SOLE   20,000 0 0
COMPUGEN LTD ORD M25722105 1,823 150,550 SH   SOLE   150,550 0 0
CONSTELLATION PHARMCETICLS I COM 210373106 726 25,200 SH   SOLE   25,200 0 0
CURIS INC COM NEW 231269200 4,341 530,000 SH   SOLE   530,000 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 2,204 38,620 SH   SOLE   38,620 0 0
DELCATH SYS INC COM NEW 24661P807 6,301 351,616 SH   SOLE   351,616 0 0
DICERNA PHARMACEUTICALS INC COM 253031108 5,009 227,388 SH   SOLE   227,388 0 0
ESSA PHARMA INC COM NEW 29668H708 3,852 322,917 SH   SOLE   322,917 0 0
EVOGENE LTD SHS M4119S104 2,820 600,000 SH   SOLE   600,000 0 0
EXACT SCIENCES CORP COM 30063P105 662 5,000 SH   SOLE   5,000 0 0
FULCRUM THERAPEUTICS INC COM 359616109 190 16,209 SH   SOLE   16,209 0 0
GAMIDA CELL LTD SHS M47364100 594 70,852 SH   SOLE   70,852 0 0
GUARDANT HEALTH INC COM 40131M109 2,426 18,825 SH   SOLE   18,825 0 0
HALOZYME THERAPEUTICS INC COM 40637H109 4,271 100,000 SH   SOLE   100,000 0 0
HELIX ACQUISITION CORP COM CL A G4444C102 2,445 215,071 SH   SOLE   215,071 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 2,195 30,000 SH   SOLE   30,000 0 0
IMMUNOGEN INC COM 45253H101 3,870 600,000 SH   SOLE   600,000 0 0
IMMUNOVANT INC COM 45258J102 4,619 100,000 SH   SOLE   100,000 0 0
INSMED INC COM PAR $.01 457669307 5,826 175,000 SH   SOLE   175,000 0 0
INTRA CELLULAR THERAPIES INC COM 46116X101 6,360 200,000 SH   SOLE   200,000 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100 464 10,000 SH   SOLE   10,000 0 0
IVERIC BIO INC COM 46583P102 899 130,043 SH   SOLE   130,043 0 0
JOUNCE THERAPEUTICS INC COM 481116101 2,847 406,665 SH   SOLE   406,665 0 0
KADMON HLDGS INC COM 48283N106 1,003 241,756 SH   SOLE   241,756 0 0
KALA PHARMACEUTICALS INC COM 483119103 693 102,198 SH   SOLE   102,198 0 0
KURA ONCOLOGY INC COM 50127T109 2,939 90,000 SH   SOLE   90,000 0 0
LARIMAR THERAPEUTICS INC COM 517125100 4,650 217,203 SH   SOLE   217,203 0 0
LEAP THERAPEUTICS INC COM 52187K101 619 275,000 SH   SOLE   275,000 0 0
MEDICENNA THERAPEUTICS CORP COM 58490H107 503 107,536 SH   SOLE   107,536 0 0
MEREO BIOPHARMA GROUP PLC ADS 589492107 1,002 280,000 SH   SOLE   280,000 0 0
MERSANA THERAPEUTICS INC COM 59045L106 286 10,763 SH   SOLE   10,763 0 0
MIRATI THERAPEUTICS INC COM 60468T105 4,393 20,000 SH   SOLE   20,000 0 0
MORPHIC HLDG INC COM 61775R105 1,726 51,433 SH   SOLE   51,433 0 0
NEXTCURE INC COM 65343E108 1,417 130,000 SH   SOLE   130,000 0 0
NKARTA INC COM 65487U108 922 15,000 SH   SOLE   15,000 0 0
OTONOMY INC COM 68906L105 1,708 263,951 SH   SOLE   263,951 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102 422 20,910 SH   SOLE   20,910 0 0
RENALYTIX AI PLC ADS 75973T101 2,260 141,253 SH   SOLE   141,253 0 0
ROCKET PHARMACEUTICALS INC COM 77313F106 548 10,000 SH   SOLE   10,000 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103 1,213 25,000 SH   SOLE   25,000 0 0
SEAGEN INC COM 81181C104 1,315 7,509 SH   SOLE   7,509 0 0
SERES THERAPEUTICS INC COM 81750R102 613 25,000 SH   SOLE   25,000 0 0
SIERRA ONCOLOGY INC COM NEW 82640U404 2,164 135,000 SH   SOLE   135,000 0 0
SOLENO THERAPEUTICS INC COM NEW 834203200 623 322,798 SH   SOLE   322,798 0 0
SURFACE ONCOLOGY INC COM 86877M209 1,201 130,000 SH   SOLE   130,000 0 0
SUTRO BIOPHARMA INC COM 869367102 4,016 185,000 SH   SOLE   185,000 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105 667 30,000 SH   SOLE   30,000 0 0
TCR2 THERAPEUTICS INC COM 87808K106 4,206 136,000 SH   SOLE   136,000 0 0
THERAPEUTICS ACQUISITION COR COM CL A 88339T103 543 39,009 SH   SOLE   39,009 0 0
TRILLIUM THERAPEUTICS INC COM NEW 89620X506 1,618 110,000 SH   SOLE   110,000 0 0
TURNING POINT THERAPEUTICS I COM 90041T108 1,966 16,131 SH   SOLE   16,131 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102 814 5,364 SH   SOLE   5,364 0 0
VERASTEM INC COM 92337C104 2,419 1,135,753 SH   SOLE   1,135,753 0 0
VERICEL CORP COM 92346J108 8,688 281,346 SH   SOLE   281,346 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 1,182 5,000 SH   SOLE   5,000 0 0
VYNE THERAPEUTICS INC COM NEW 92941V100 552 349,624 SH   SOLE   349,624 0 0
ZENTALIS PHARMACEUTICALS INC COM 98943L107 519 10,000 SH   SOLE   10,000 0 0
ZYMEWORKS INC COM 98985W102 1,457 30,834 SH   SOLE   30,834 0 0