The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
1LIFE HEALTHCARE INC COM 68269G107 144,446 3,309,194 SH   SOLE   3,309,194 0 0
908 DEVICES INC COM 65443P102 4,271 75,000 SH   SOLE   75,000 0 0
ABBVIE INC COM 00287Y109 148,821 1,388,904 SH   SOLE   1,388,904 0 0
ABCELLERA BIOLOGICS INC COM 00288U106 20,120 500,000 SH   SOLE   500,000 0 0
ADC THERAPEUTICS SA SHS H0036K147 216,349 6,758,794 SH   SOLE   6,758,794 0 0
AKERO THERAPEUTICS INC COM 00973Y108 59,922 2,322,557 SH   SOLE   2,322,557 0 0
ALLAKOS INC COM 01671P100 373,443 2,667,451 SH   SOLE   2,667,451 0 0
ALLOVIR INC COM 019818103 89,396 2,325,595 SH   SOLE   2,325,595 0 0
ALX ONCOLOGY HLDGS INC COM 00166B105 82,786 960,400 SH   SOLE   960,400 0 0
AMEDISYS INC COM 023436108 39,154 133,480 SH   SOLE   133,480 0 0
AMICUS THERAPEUTICS INC COM 03152W109 476,127 20,620,490 SH   SOLE   20,620,490 0 0
ANNEXON INC COM 03589W102 86,304 3,448,030 SH   SOLE   3,448,030 0 0
ANTHEM INC COM 036752103 78,453 244,332 SH   SOLE   244,332 0 0
APREA THERAPEUTICS INC COM 03836J102 6,242 1,268,718 SH   SOLE   1,268,718 0 0
ARDELYX INC COM 039697107 22,736 3,514,100 SH   SOLE   3,514,100 0 0
ARGENX SE SPONSORED ADR 04016X101 270,065 918,307 SH   SOLE   918,307 0 0
ATARA BIOTHERAPEUTICS INC COM 046513107 134,722 6,863,070 SH   SOLE   6,863,070 0 0
ATEA PHARMACEUTICALS INC COM 04683R106 93,241 2,231,710 SH   SOLE   2,231,710 0 0
ATRECA INC CL A COM 04965G109 39,988 2,476,068 SH   SOLE   2,476,068 0 0
AVITA THERAPEUTICS INC COM 05380C102 31,723 1,707,386 SH   SOLE   1,707,386 0 0
AYALA PHARMACEUTICALS INC COM 05465V108 7,606 667,816 SH   SOLE   667,816 0 0
BEAM THERAPEUTICS INC COM 07373V105 308,457 3,778,262 SH   SOLE   3,778,262 0 0
BIOGEN INC COM 09062X103 52,950 216,247 SH   SOLE   216,247 0 0
BIONTECH SE SPONSORED ADS 09075V102 47,342 580,746 SH   SOLE   580,746 0 0
CABALETTA BIO INC COM 12674W109 17,201 1,378,319 SH   SOLE   1,378,319 0 0
CASTLIGHT HEALTH INC CL B 14862Q100 13 10,229 SH   SOLE   10,229 0 0
CATALENT INC COM 148806102 32,732 314,519 SH   SOLE   314,519 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 47,508 2,711,616 SH   SOLE   2,711,616 0 0
CENTENE CORP DEL COM 15135B101 33,314 554,962 SH   SOLE   554,962 0 0
CIGNA CORP NEW COM 125523100 79,752 383,093 SH   SOLE   383,093 0 0
CYTOSORBENTS CORP COM NEW 23283X206 16,371 2,054,131 SH   SOLE   2,054,131 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 253,275 4,437,968 SH   SOLE   4,437,968 0 0
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201 5,415 1,216,844 SH   SOLE   1,216,844 0 0
EARGO INC COM 270087109 5,804 129,488 SH   SOLE   129,488 0 0
EIDOS THERAPEUTICS INC COM 28249H104 59,513 452,295 SH   SOLE   452,295 0 0
EPIZYME INC COM 29428V104 102,630 9,450,305 SH   SOLE   9,450,305 0 0
FATE THERAPEUTICS INC COM 31189P102 1,148,422 12,629,737 SH   SOLE   12,629,737 0 0
GENMARK DIAGNOSTICS INC COM 372309104 66,246 4,537,400 SH   SOLE   4,537,400 0 0
GILEAD SCIENCES INC COM 375558103 133,348 2,288,846 SH   SOLE   2,288,846 0 0
GRITSTONE ONCOLOGY INC COM 39868T105 12,056 3,059,794 SH   SOLE   3,059,794 0 0
GW PHARMACEUTICALS PLC ADS 36197T103 94,138 815,681 SH   SOLE   815,681 0 0
HOOKIPA PHARMA INC COM 43906K100 20,438 1,842,902 SH   SOLE   1,842,902 0 0
ICU MED INC COM 44930G107 51,789 241,454 SH   SOLE   241,454 0 0
IGM BIOSCIENCES INC COM 449585108 302,433 3,425,455 SH   SOLE   3,425,455 0 0
IMMATICS N.V SHS N44445109 22,317 2,068,301 SH   SOLE   2,068,301 0 0
IMMUNOGEN INC COM 45253H101 67,907 10,528,179 SH   SOLE   10,528,179 0 0
INVITAE CORP COM 46185L103 220,059 5,263,309 SH   SOLE   5,263,309 0 0
ITAMAR MED LTD SPONSORED ADS 465437101 14,130 711,500 SH   SOLE   711,500 0 0
KRYSTAL BIOTECH INC COM 501147102 100,502 1,675,036 SH   SOLE   1,675,036 0 0
KYMERA THERAPEUTICS INC COM 501575104 168,670 2,720,489 SH   SOLE   2,720,489 0 0
MEDAVAIL HOLDINGS INC COM 58406B103 176,457 11,724,726 SH   SOLE   11,724,726 0 0
NEOLEUKIN THERAPEUTICS INC COM 64049K104 58,259 4,131,869 SH   SOLE   4,131,869 0 0
NEVRO CORP COM 64157F103 76,841 443,909 SH   SOLE   443,909 0 0
NURIX THERAPEUTICS INC COM 67080M103 93,581 2,846,125 SH   SOLE   2,846,125 0 0
OAK STR HEALTH INC COM 67181A107 178,936 2,925,711 SH   SOLE   2,925,711 0 0
OUTSET MED INC COM 690145107 3,979 70,000 SH   SOLE   70,000 0 0
OVID THERAPEUTICS INC COM 690469101 282 121,950 SH   SOLE   121,950 0 0
PANDION THERAPEUTICS INC COM 698340106 20,771 1,398,705 SH   SOLE   1,398,705 0 0
PLIANT THERAPEUTICS INC COM 729139105 76,984 3,388,376 SH   SOLE   3,388,376 0 0
PPD INC COM 69355F102 28,170 823,192 SH   SOLE   823,192 0 0
PRA HEALTH SCIENCES INC COM 69354M108 33,334 265,736 SH   SOLE   265,736 0 0
PROFOUND MED CORP COM NEW 74319B502 16,966 825,197 SH   SOLE   825,197 0 0
PULMONX CORP COM 745848101 18,981 275,000 SH   SOLE   275,000 0 0
REGENXBIO INC COM 75901B107 96,322 2,123,492 SH   SOLE   2,123,492 0 0
REPARE THERAPEUTICS INC COM 760273102 90,816 2,647,696 SH   SOLE   2,647,696 0 0
REPLIMUNE GROUP INC COM 76029N106 152,348 3,993,399 SH   SOLE   3,993,399 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 2,606 744,582 SH   SOLE   744,582 0 0
SANOFI SPONSORED ADR 80105N105 96,436 1,984,690 SH   SOLE   1,984,690 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103 140,571 2,896,589 SH   SOLE   2,896,589 0 0
SEER INC COM CL A 81578P106 7,018 125,000 SH   SOLE   125,000 0 0
SELECTQUOTE INC COM 816307300 38,278 1,844,719 SH   SOLE   1,844,719 0 0
SHATTUCK LABS INC COM 82024L103 294,540 5,619,914 SH   SOLE   5,619,914 0 0
STEREOTAXIS INC COM NEW 85916J409 15,796 3,103,327 SH   SOLE   3,103,327 0 0
STOKE THERAPEUTICS INC COM 86150R107 166,358 2,686,234 SH   SOLE   2,686,234 0 0
SYROS PHARMACEUTICALS INC COM 87184Q107 2,303 212,291 SH   SOLE   212,291 0 0
TCR2 THERAPEUTICS INC COM 87808K106 87,621 2,832,888 SH   SOLE   2,832,888 0 0
TRICIDA INC COM 89610F101 3,182 451,377 SH   SOLE   451,377 0 0
UBER TECHNOLOGIES INC COM 90353T100 42,526 833,845 SH   SOLE   833,845 0 0
UNIQURE NV SHS N90064101 37,174 1,028,898 SH   SOLE   1,028,898 0 0
UNITEDHEALTH GROUP INC COM 91324P102 78,776 224,639 SH   SOLE   224,639 0 0
VAPOTHERM INC COM 922107107 672 25,000 SH   SOLE   25,000 0 0
VESPER HEALTHCARE ACQSTN COR COM CL A 92538T104 11,310 1,000,000 SH   SOLE   1,000,000 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105 622 79,018 SH   SOLE   79,018 0 0
XERIS PHARMACEUTICALS INC COM 98422L107 11,795 2,397,441 SH   SOLE   2,397,441 0 0
YUMANITY THERAPEUTICS INC COM 98872L102 10,387 611,003 SH   SOLE   611,003 0 0
ZENTALIS PHARMACEUTICALS INC COM 98943L107 125,508 2,416,406 SH   SOLE   2,416,406 0 0
ZYMEWORKS INC COM 98985W102 51,433 1,088,300 SH   SOLE   1,088,300 0 0