The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABBVIE INC COM 00287Y109 145,295 1,356,000 SH   SOLE   1,356,000 0 0
ACADIA PHARMACEUTICALS INC COM 004225108 28,205 527,600 SH   SOLE   527,600 0 0
ACCELERON PHARMA INC COM 00434H108 38,254 299,000 SH   SOLE   299,000 0 0
ACCOLADE INC COM 00437E102 1,740 40,000 SH   SOLE   40,000 0 0
ALBIREO PHARMA INC COM 01345P106 4,689 125,000 SH   SOLE   125,000 0 0
ALDEYRA THERAPEUTICS INC COM 01438T106 9,844 1,435,000 SH   SOLE   1,435,000 0 0
ALPHATEC HLDGS INC COM NEW 02081G201 26,875 1,850,873 SH   SOLE   1,850,873 0 0
ALPINE IMMUNE SCIENCES INC COM 02083G100 15,725 1,248,000 SH   SOLE   1,248,000 0 0
AMERICAN WELL CORP CL A 03044L105 1,267 50,000 SH   SOLE   50,000 0 0
ANIKA THERAPEUTICS INC COM 035255108 33,085 731,000 SH   SOLE   731,000 0 0
ANNEXON INC COM 03589W102 1,752 70,000 SH   SOLE   70,000 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106 44,273 774,000 SH   SOLE   774,000 0 0
ARENA PHARMACEUTICALS INC COM NEW 040047607 47,711 621,000 SH   SOLE   621,000 0 0
ARVINAS INC COM 04335A105 151,800 1,787,358 SH   SOLE   1,787,358 0 0
ARYA SCIENCES ACQUISITION CO COM CL A G3166W106 5,425 500,000 SH   SOLE   500,000 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108 114,977 2,300,000 SH   SOLE   2,300,000 0 0
ATHIRA PHARMA INC COM 04746L104 35,753 1,043,873 SH   SOLE   1,043,873 0 0
ATRICURE INC COM 04963C209 24,862 446,600 SH   SOLE   446,600 0 0
AURINIA PHARMACEUTICALS INC COM 05156V102 27,660 2,000,000 SH   SOLE   2,000,000 0 0
AVANTOR INC COM 05352A100 184,853 6,566,700 SH   SOLE   6,566,700 0 0
BAUSCH HEALTH COS INC COM 071734107 41,018 1,972,000 SH   SOLE   1,972,000 0 0
BCLS ACQUISITION CORP COM CL A G0904B105 5,570 500,000 SH   SOLE   500,000 0 0
BCTG ACQUISITION CORP COM 05492W103 3,432 300,000 SH   SOLE   300,000 0 0
BELLUS HEALTH INC NEW COM NEW 07987C204 17,522 5,726,000 SH   SOLE   5,726,000 0 0
BIOATLA INC COM 09077B104 1,701 50,000 SH   SOLE   50,000 0 0
BIOGEN INC COM 09062X903 60,749 248,100 SH Call SOLE   248,100 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 42,152 491,800 SH   SOLE   491,800 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 44,663 521,100 SH Call SOLE   521,100 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 87,067 992,900 SH   SOLE   992,900 0 0
BIOXCEL THERAPEUTICS INC COM 09075P105 25,271 547,000 SH   SOLE   547,000 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 26,916 240,000 SH   SOLE   240,000 0 0
CARDIFF ONCOLOGY INC COM 14147L108 28,910 1,607,000 SH   SOLE   1,607,000 0 0
CARDINAL HEALTH INC COM 14149Y108 43,276 808,000 SH   SOLE   808,000 0 0
CASTLE BIOSCIENCES INC COM 14843C105 10,073 150,000 SH   SOLE   150,000 0 0
CATALENT INC COM 148806102 35,072 337,000 SH   SOLE   337,000 0 0
CERTARA INC COM 15687V109 13,645 404,663 SH   SOLE   404,663 0 0
CHANGE HEALTHCARE INC COM 15912K100 57,481 3,082,100 SH   SOLE   3,082,100 0 0
CHEMOCENTRYX INC COM 16383L106 46,873 757,000 SH   SOLE   757,000 0 0
CODEXIS INC COM 192005106 13,098 600,000 SH   SOLE   600,000 0 0
COGENT BIOSCIENCES INC COM 19240Q201 5,836 519,645 SH   SOLE   519,645 0 0
COLLEGIUM PHARMACEUTICAL INC COM 19459J104 24,817 1,239,000 SH   SOLE   1,239,000 0 0
CURIS INC COM NEW 231269200 19,182 2,342,100 SH   SOLE   2,342,100 0 0
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201 17,800 4,000,000 SH   SOLE   4,000,000 0 0
ESSA PHARMA INC COM NEW 29668H708 30,517 2,558,000 SH   SOLE   2,558,000 0 0
EXACT SCIENCES CORP COM 30063P105 32,725 247,000 SH   SOLE   247,000 0 0
FIVE PRIME THERAPEUTICS INC COM 33830X104 5,103 300,000 SH   SOLE   300,000 0 0
GRITSTONE ONCOLOGY INC COM 39868T105 8,361 2,122,064 SH   SOLE   2,122,064 0 0
HARPOON THERAPEUTICS INC COM 41358P106 13,039 785,000 SH   SOLE   785,000 0 0
HEALTH SCIENCES ACQ CORP 2 ORD SHS G4411D109 5,124 400,000 SH   SOLE   400,000 0 0
HELIX ACQUISITION CORP COM CL A G4444C102 4,548 400,000 SH   SOLE   400,000 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 85,534 1,169,300 SH   SOLE   1,169,300 0 0
I MAB SPONSORED ADS 44975P103 75,016 1,591,000 SH   SOLE   1,591,000 0 0
IGM BIOSCIENCES INC COM 449585108 7,063 80,000 SH   SOLE   80,000 0 0
INOZYME PHARMA INC COM 45790W108 200 9,683 SH   SOLE   9,683 0 0
INTELLIA THERAPEUTICS INC COM 45826J105 16,483 303,000 SH   SOLE   303,000 0 0
ITEOS THERAPEUTICS INC COM 46565G104 3,131 92,574 SH   SOLE   92,574 0 0
KADMON HLDGS INC COM 48283N106 39,716 9,570,000 SH   SOLE   9,570,000 0 0
KEROS THERAPEUTICS INC COM 492327101 2,822 40,000 SH   SOLE   40,000 0 0
KINIKSA PHARMACEUTICALS LTD COM CL A G5269C101 17,057 965,300 SH   SOLE   965,300 0 0
KURA ONCOLOGY INC COM 50127T109 11,354 347,645 SH   SOLE   347,645 0 0
LIFESCI ACQUISITION II CORP COM 53229E103 4,268 400,000 SH   SOLE   400,000 0 0
LIGAND PHARMACEUTICALS INC COM NEW 53220K504 6,176 62,100 SH   SOLE   62,100 0 0
LILLY ELI & CO COM 532457108 136,845 810,500 SH   SOLE   810,500 0 0
MARAVAI LIFESCIENCES HLDGS I COM CL A 56600D107 96,654 3,445,772 SH   SOLE   3,445,772 0 0
MEDTRONIC PLC SHS G5960L103 35,259 301,000 SH   SOLE   301,000 0 0
MIRATI THERAPEUTICS INC COM 60468T105 83,463 380,000 SH   SOLE   380,000 0 0
NATERA INC COM 632307104 47,750 479,800 SH   SOLE   479,800 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 28,755 300,000 SH   SOLE   300,000 0 0
NURIX THERAPEUTICS INC COM 67080M103 1,644 50,000 SH   SOLE   50,000 0 0
OAK STR HEALTH INC COM 67181A107 9,174 150,000 SH   SOLE   150,000 0 0
OCULAR THERAPEUTIX INC COM 67576A100 5,175 250,000 SH   SOLE   250,000 0 0
OLEMA PHARMACEUTICALS INC COM 68062P106 12,982 270,000 SH   SOLE   270,000 0 0
ONCOSEC MED INC COM 68234L306 12,590 1,952,000 SH   SOLE   1,952,000 0 0
ORGANOGENESIS HLDGS INC COM 68621F102 41,577 5,521,500 SH   SOLE   5,521,500 0 0
OUTSET MED INC COM 690145107 5,684 100,000 SH   SOLE   100,000 0 0
PANACEA ACQUISITION CORP UNIT 99/99/9999 698102209 3,828 300,000 SH   SOLE   300,000 0 0
PHATHOM PHARMACEUTICALS INC COM 71722W107 5,066 152,500 SH   SOLE   152,500 0 0
QUEST DIAGNOSTIC INC COM 74834L100 94,395 792,100 SH   SOLE   792,100 0 0
REATA PHARMACEUTICALS INC CL A 75615P103 15,538 125,690 SH   SOLE   125,690 0 0
RELAY THERAPEUTICS INC COM 75943R102 1,247 30,000 SH   SOLE   30,000 0 0
ROCKET PHARMACEUTICALS INC COM 77313F106 2,742 50,000 SH   SOLE   50,000 0 0
SAREPTA TEHRAPEUTICS INC COM 803607100 37,065 217,400 SH   SOLE   217,400 0 0
SCYNEXIS INC COM NEW 811292200 9,601 1,255,000 SH   SOLE   1,255,000 0 0
SHATTUCK LABS INC COM 82024L103 49,203 938,813 SH   SOLE   938,813 0 0
SI BONE INC COM 825704109 19,133 639,884 SH   SOLE   639,884 0 0
SIGILON THERAPEUTICS INC COM 82657L107 33,045 688,000 SH   SOLE   688,000 0 0
SOTERA HEALTH CO COM 83601L102 19,208 700,000 SH   SOLE   700,000 0 0
SURGERY PARTNERS INC COM 86881A100 15,404 531,000 SH   SOLE   531,000 0 0
SUTRO BIOPHARMA INC COM 869367102 13,590 626,000 SH   SOLE   626,000 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105 73,570 3,308,000 SH   SOLE   3,308,000 0 0
TAYSHA GENE THERAPIES INC COM SHS 877619106 10,404 392,000 SH   SOLE   392,000 0 0
TRILLIUM THERAPEUTICS INC COM NEW 89620X506 46,854 3,185,200 SH   SOLE   3,185,200 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 34,813 147,300 SH   SOLE   147,300 0 0
VESPER HEALTHCARE ACQSTN COR UNIT 99/99/9999 92538T203 7,272 600,000 SH   SOLE   600,000 0 0
ZENTALIS PHARMACEUTICALS INC COM 98943L107 58,952 1,135,000 SH   SOLE   1,135,000 0 0
ZYMEWORKS INC COM 98985W102 27,321 578,100 SH   SOLE   578,100 0 0