The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
4D MOLECULAR THERAPEUTICS IN COM 35104E100 4,145 100,000 SH   OTR   100,000 0 0
908 DEVICES INC COM 65443P102 4,271 75,000 SH   OTR   75,000 0 0
ABBVIE INC COM 00287Y109 123,223 1,150,000 SH   OTR   1,150,000 0 0
ACACIA COMMUNICATIONS INC COM 00401C108 7,296 100,000 SH   OTR   100,000 0 0
ACCELERON PHARMA INC COM 00434H108 332,644 2,600,000 SH   OTR   2,600,000 0 0
ADVERUM BIOTECHNOLOGIES INC COM 00773U108 16,260 1,500,000 SH   OTR   1,500,000 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104 43,330 1,000,000 SH   OTR   1,000,000 0 0
ALBIREO PHARMA INC COM 01345P106 9,378 250,000 SH   OTR   250,000 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 198,589 853,300 SH   OTR   853,300 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 45,490 350,000 SH   OTR   350,000 0 0
ALPHABET INC CAP STK CL C 02079K107 632,593 361,094 SH   OTR   361,094 0 0
ALPINE IMMUNE SCIENCES INC COM 02083G100 2,520 200,000 SH   OTR   200,000 0 0
AMICUS THERAPEUTICS INC COM 03152W109 28,863 1,250,000 SH   OTR   1,250,000 0 0
AMYRIS INC COM NEW 03236M200 108,063 17,500,000 SH   OTR   17,500,000 0 0
ANNEXON INC COM 03589W102 38,978 1,557,261 SH   OTR   1,557,261 0 0
ANTHEM INC COM 036752103 409,390 1,275,000 SH   OTR   1,275,000 0 0
AON PLC SHS CL A G0403H108 479,903 2,271,514 SH   OTR   2,271,514 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106 130,130 2,275,000 SH   OTR   2,275,000 0 0
APELLIS PHARMACEUTICALS INC NOTE 3.500% 9/1 03753UAB2 5,930 3,522,000 PRN   OTR   3,522,000 0 0
ARAMARK COM 03852U106 424,202 11,023,949 SH   OTR   11,023,949 0 0
ARENA PHARMACEUTICALS INC COM NEW 040047607 57,623 750,000 SH   OTR   750,000 0 0
ARROWHEAD PHARMACEUTICALS IN COM 04280A100 5,187 67,600 SH   OTR   67,600 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101 166,780 1,000,000 SH   OTR   1,000,000 0 0
ATENTO S A SHS L0427L204 18,227 2,230,357 SH   OTR   2,230,357 0 0
AVROBIO INC COM 05455M100 11,082 795,000 SH   OTR   795,000 0 0
BIOATLA INC COM 09077B104 66,900 1,967,060 SH   OTR   1,967,060 0 0
BIOGEN INC COM 09062X103 25,221 103,000 SH   OTR   103,000 0 0
BLACKSTONE GROUP INC COM CL A 09260D107 252,233 3,891,886 SH   OTR   3,891,886 0 0
BOSTON SCIENTIFIC CORP COM 101137107 475,918 13,238,319 SH   OTR   13,238,319 0 0
BRISTOL-MYERS SQUIBB CO COM 110122108 15,508 250,000 SH   OTR   250,000 0 0
BRISTOL-MYERS SQUIBB CO RIGHT 99/99/9999 110122157 14,768 21,400,000 SH   OTR   21,400,000 0 0
BROADCOM INC COM 11135F101 272,778 622,995 SH   OTR   622,995 0 0
BROADMARK RLTY CAP INC COM 11135B100 73,136 7,170,213 SH   OTR   7,170,213 0 0
BROADMARK RLTY CAP INC *W EXP 11/15/202 11135B118 1,937 7,174,613 SH   OTR   7,174,613 0 0
CARA THERAPEUTICS INC COM 140755109 37,295 2,465,000 SH   OTR   2,465,000 0 0
CASCADE ACQUISITION CORP UNIT 99/99/9999 147151203 10,346 990,000 SH   OTR   990,000 0 0
CENTENE CORP DEL COM 15135B101 411,206 6,850,000 SH   OTR   6,850,000 0 0
CEREVEL THERAPEUTICS HLDNG I *W EXP 06/09/202 15678U102 758 134,175 SH   OTR   134,175 0 0
CHARTER COMMUNICATIONS INC N CL A 16119P108 361,822 546,931 SH   OTR   546,931 0 0
CLEVER LEAVES HOLDINGS INC COM 186760104 28,730 2,478,079 SH   OTR   2,478,079 0 0
CLOVIS ONCOLOGY INC NOTE 1.250% 5/0 189464AC4 36,077 51,910,000 PRN   OTR   51,910,000 0 0
COGENT BIOSCIENCES INC COM 19240Q201 6,738 600,000 SH   OTR   600,000 0 0
CONSTELLATION PHARMCETICLS I COM 210373106 21,600 750,000 SH   OTR   750,000 0 0
CORELOGIC INC COM 21871D103 44,384 574,028 SH   OTR   574,028 0 0
CURIS INC COM NEW 231269200 5,938 725,000 SH   OTR   725,000 0 0
CYTOKINETICS INC COM NEW 23282W605 49,872 2,400,000 SH   OTR   2,400,000 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 17,121 300,000 SH   OTR   300,000 0 0
DERMTECH INC COM 24984K105 27,934 861,090 SH   OTR   861,090 0 0
ENANTA PHARMACEUTICALS INC COM 29251M106 74,728 1,775,000 SH   OTR   1,775,000 0 0
EQUIFAX INC COM 294429105 71,483 370,684 SH   OTR   370,684 0 0
EQUILLIUM INC COM 29446K106 3,745 700,000 SH   OTR   700,000 0 0
EXELIXIS INC COM 30161Q104 220,770 11,000,000 SH   OTR   11,000,000 0 0
FACEBOOK INC CL A 30303M102 315,228 1,154,005 SH   OTR   1,154,005 0 0
FATE THERAPEUTICS INC COM 31189P102 272,790 3,000,000 SH   OTR   3,000,000 0 0
FIBROGEN INC COM 31572Q808 70,471 1,900,000 SH   OTR   1,900,000 0 0
FIDELITY NATL INFORMATION SV COM 31620M106 445,474 3,149,118 SH   OTR   3,149,118 0 0
FIVE PRIME THERAPEUTICS INC COM 33830X104 6,804 400,000 SH   OTR   400,000 0 0
GENERATION BIO CO COM 37148K100 64,321 2,268,819 SH   OTR   2,268,819 0 0
GOL LINHAS AEREAS INTELIGENT SPON ADR PFD NEW 38045R206 843 85,838 SH   OTR   85,838 0 0
GOSSAMER BIO INC NOTE 5.000% 6/0 38341PAA0 9,032 10,000,000 PRN   OTR   10,000,000 0 0
GRIFOLS S A SP ADR REP B NVT 398438408 20,561 1,115,000 SH   OTR 1 1,115,000 0 0
HILTON WORLDWIDE HLDGS INC COM 43300A203 182,515 1,640,437 SH   OTR   1,640,437 0 0
HOWMET AEROSPACE INC COM 443201108 139,603 4,891,479 SH   OTR   4,891,479 0 0
HUMANCO ACQUISITION CORP UNIT 12/08/2023 44487N208 4,408 400,000 SH   OTR   400,000 0 0
IMMUNOGEN INC COM 45253H101 6,450 1,000,000 SH   OTR   1,000,000 0 0
INHIBRX INC COM 45720L107 16,815 510,000 SH   OTR   510,000 0 0
INSMED INC NOTE 1.750% 1/1 457669AA7 36,552 32,500,000 PRN   OTR   32,500,000 0 0
INTELLIA THERAPEUTICS INC COM 45826J105 12,240 225,000 SH   OTR   225,000 0 0
INVENTIVA SA ADS 46124U107 2,320 160,000 SH   OTR   160,000 0 0
IONIS PHARMACEUTICALS INC COM 462222100 42,405 750,000 SH   OTR   750,000 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100 278,400 6,000,000 SH   OTR   6,000,000 0 0
IQIYI INC NOTE 3.750%12/0 46267XAB4 29,894 29,689,000 PRN   OTR   29,689,000 0 0
IQIYI INC NOTE 2.000% 4/0 46267XAD0 71,760 81,762,000 PRN   OTR   81,762,000 0 0
IQIYI INC NOTE 4.000%12/1 46267XAE8 20,000 20,000,000 PRN   OTR   20,000,000 0 0
IQVIA HLDGS INC COM 46266C105 724,475 4,043,506 SH   OTR   4,043,506 0 0
ISIS PHARMACEUTICALS INC DEL NOTE 1.000%11/1 464337AJ3 2,733 2,500,000 PRN   OTR   2,500,000 0 0
IVERIC BIO INC COM 46583P102 5,215 754,740 SH   OTR   754,740 0 0
KANSAS CITY SOUTHERN COM NEW 485170302 72,344 354,400 SH   OTR   354,400 0 0
KARUNA THERAPEUTICS INC COM 48576A100 71,113 700,000 SH   OTR   700,000 0 0
KARYOPHARM THERAPEUTICS INC NOTE 3.000%10/1 48576UAA4 43,527 35,000,000 PRN   OTR   35,000,000 0 0
KE HLDGS INC SPONSORED ADS 482497104 21,108 343,000 SH   OTR   343,000 0 0
KINNATE BIOPHARMA INC COM 49705R105 9,945 250,000 SH   OTR   250,000 0 0
KRYSTAL BIOTECH INC COM 501147102 31,500 525,000 SH   OTR   525,000 0 0
KURA ONCOLOGY INC COM 50127T109 4,083 125,000 SH   OTR   125,000 0 0
LANTHEUS HLDGS INC COM 516544103 35,749 2,650,000 SH   OTR   2,650,000 0 0
LUFAX HOLDING LTD ADS REP SHS CL A 54975P102 76,080 5,357,750 SH   OTR   5,357,750 0 0
MARVELL TECHNOLOGY GROUP LTD ORD G5876H105 5,943 125,000 SH Call OTR   125,000 0 0
MICROSOFT CORP COM 594918104 391,052 1,758,168 SH   OTR   1,758,168 0 0
MIRATI THERAPEUTICS INC COM 60468T105 192,185 875,000 SH   OTR   875,000 0 0
MOMO INC NOTE 1.250% 7/0 60879BAB3 93,459 110,077,000 PRN   OTR   110,077,000 0 0
NEW ORIENTAL ED & TECHNOLOGY SPON ADR 647581107 214,480 1,154,300 SH   OTR   1,154,300 0 0
NEW YORK TIMES CO CL A 650111107 338,852 6,545,329 SH   OTR   6,545,329 0 0
NOVAVAX INC COM NEW 670002401 30,665 275,000 SH   OTR   275,000 0 0
NUANCE COMMUNICATIONS INC DBCV 1.000%12/1 67020YAK6 13,052 7,000,000 PRN   OTR   7,000,000 0 0
PACIFIC BIOSCIENCES CALIF IN COM 69404D108 54,474 2,100,000 SH   OTR   2,100,000 0 0
PANACEA ACQUISITION CORP CL A 698102100 29,250 2,500,000 SH   OTR   2,500,000 0 0
PG&E CORP COM 69331C108 90,859 7,292,042 SH   OTR   7,292,042 0 0
PLAYA HOTELS & RESORTS NV SHS N70544106 89,219 14,994,867 SH   OTR   14,994,867 0 0
PLIANT THERAPEUTICS INC COM 729139105 17,364 764,262 SH   OTR   764,262 0 0
PRAXIS PRECISION MEDICINES I COM 74006W108 13,755 250,000 SH   OTR   250,000 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102 48,888 2,425,000 SH   OTR   2,425,000 0 0
QIAGEN NV SHS NEW N72482123 172,120 3,256,771 SH   OTR   3,256,771 0 0
RADIUS HEALTH INC COM NEW 750469207 37,638 2,107,400 SH   OTR   2,107,400 0 0
RADIUS HEALTH INC NOTE 3.000% 9/0 750469AA6 5,995 6,783,000 PRN   OTR   6,783,000 0 0
RAYTHEON TECHNOLOGIES CORP COM 75513E101 324,820 4,542,306 SH   OTR   4,542,306 0 0
READY CAPITAL CORP COM 75574U101 16,810 1,350,226 SH   OTR   1,350,226 0 0
ROCKET PHARMACEUTICALS INC COM 77313F106 10,968 200,000 SH   OTR   200,000 0 0
SAGE THERAPEUTICS INC COM 78667J108 90,836 1,050,000 SH   OTR   1,050,000 0 0
SALESFORCE COM INC COM 79466L302 313,555 1,409,045 SH   OTR   1,409,045 0 0
SAREPTA THERAPEUTICS INC COM 803607100 102,294 600,000 SH   OTR   600,000 0 0
SAVARA INC COM 805111101 5,120 4,452,086 SH   OTR   4,452,086 0 0
SHATTUCK LABS INC COM 82024L103 5,241 100,000 SH   OTR   100,000 0 0
SHERWIN WILLIAMS CO COM 824348106 286,149 389,366 SH   OTR   389,366 0 0
SILVERBACK THERAPEUTICS INC COM 82835W108 2,207 47,620 SH   OTR   47,620 0 0
SPDR S&P 500 ETF TR TR UNIT 78462F103 510,346 1,365,000 SH Put OTR   1,365,000 0 0
SURFACE ONCOLOGY INC COM 86877M209 9,240 1,000,000 SH   OTR   1,000,000 0 0
TG THERAPEUTICS INC COM 88322Q108 5,202 100,000 SH   OTR   100,000 0 0
THERAVANCE BIOPHARMA INC NOTE 3.250%11/0 88339KAA0 53,806 56,695,000 PRN   OTR   56,695,000 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102 518,994 1,114,248 SH   OTR   1,114,248 0 0
TIFFANY & CO NEW COM 886547108 300,626 2,287,000 SH   OTR   2,287,000 0 0
TIGA ACQUISITION CORP UNIT 99/99/9999 G88672129 11,426 1,080,000 SH   OTR   1,080,000 0 0
T-MOBILE US INC COM 872590104 532,547 3,949,181 SH   OTR   3,949,181 0 0
TRANSUNION COM 89400J107 172,056 1,734,082 SH   OTR   1,734,082 0 0
UNIQURE NV SHS N90064101 10,839 300,000 SH   OTR   300,000 0 0
VISA INC COM CL A 92826C839 487,353 2,228,104 SH   OTR   2,228,104 0 0
WABTEC COM 929740108 365,808 4,997,371 SH   OTR   4,997,371 0 0
WILLIS TOWERS WATSON PLC LTD SHS G96629103 202,780 962,500 SH   OTR 1 962,500 0 0
XPO LOGISTICS INC COM 983793100 13,112 110,000 SH   OTR   110,000 0 0
ZEALAND PHARMA A/S SPONSORED ADR 98920Y304 18,329 510,000 SH   OTR   510,000 0 0
ZOGENIX INC COM NEW 98978L204 44,978 2,250,000 SH   OTR   2,250,000 0 0
ZYMEWORKS INC COM 98985W102 35,445 750,000 SH   OTR   750,000 0 0