The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACUTUS MEDICAL INC COM 005111109 21,607 749,990 SH   SOLE   749,990 0 0
ADAMAS PHARMACEUTICALS INC COM 00548A106 6,442 1,487,800 SH   SOLE   1,487,800 0 0
AKOUS INC COM 00973J101 901 45,459 SH   SOLE   45,459 0 0
AMARIN CORP PLC SPONSORED ADR NEW 023111206 1,100 225,000 SH   SOLE   225,000 0 0
APTOSE BIOSCIENCES INC COM NEW 03835T200 3,504 800,000 SH   SOLE   800,000 0 0
AVEO BIOSCIENCES INC COM NEW 053588307 339 58,800 SH   SOLE   58,800 0 0
BIOHAVEN PHARMACEUTICAL HLDG COM G11196105 9,771 114,000 SH   SOLE   114,000 0 0
BIOLINERX LTD SPONSORED ADS 09071M205 42 16,667 SH   SOLE   16,667 0 0
CARDIFF ONCOLOGY INC COM 14147L108 29,908 1,662,500 SH   SOLE   1,662,500 0 0
CATABASIS PHARMACEUTICALS INC COM NEW 14875P206 402 187,750 SH   SOLE   187,750 0 0
CATALYST BIOSCIENCES INC COM NEW 14888D208 939 148,800 SH   SOLE   148,800 0 0
CELLDEX THERAPEUTICS INC COM NEW 15117B202 17,380 992,000 SH   SOLE   992,000 0 0
CERECOR INC COM 15671L109 6,917 2,620,000 SH   SOLE   2,620,000 0 0
CHEMOCENTRYX INC COM 16383L106 21,672 350,000 SH   SOLE   350,000 0 0
CHIMERIX INC COM 16934W106 19,110 3,956,500 SH   SOLE   3,956,500 0 0
CODEXIS INC COM 192005106 30,562 1,400,000 SH   SOLE   1,400,000 0 0
CONCERT PHARMACEUTICALS INC COM 206022105 3,211 254,000 SH   SOLE   254,000 0 0
CONTRAFECT CORP COM NEW 212326300 2,222 440,000 SH   SOLE   440,000 0 0
CYTOKINETICS INC COM NEW 23282W605 12,111 582,800 SH   SOLE   582,800 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 12,670 222,000 SH   SOLE   222,000 0 0
EDAP TMS SA SPONSORED ADR 268311107 3,399 657,500 SH   SOLE   657,500 0 0
EIDOS THERAPEUTICS INC COM 28249H104 41,520 315,550 SH   SOLE   315,550 0 0
ESSA PHARMA INC COM NEW 29668H708 3,389 284,050 SH   SOLE   284,050 0 0
ETON PHARMACEUTICALS INC COM 29772L108 32,845 4,040,000 SH   SOLE   4,040,000 0 0
FIBROGEN INC COM 31572Q808 5,452 147,000 SH   SOLE   147,000 0 0
FIVE PRIME THERAPEUTICS INC COM 33830X104 6,496 381,900 SH   SOLE   381,900 0 0
FORTRESS BIOTECH INC COM 34960Q109 12,323 3,887,500 SH   SOLE   3,887,500 0 0
FS DEV CORP COM CL A 303020101 7,748 704,400 SH   SOLE   704,400 0 0
FULCRUM THERAPEUTICS INC COM 359616109 1,034 88,300 SH   SOLE   88,300 0 0
HARROW HEALTH INC COM 415858109 21,029 3,065,416 SH   SOLE   3,065,416 0 0
INFINITY PHARMACEUTICALS INC COM 45665G303 6,724 3,171,800 SH   SOLE   3,171,800 0 0
KALVISTA PHARMACEUTICALS INC COM 483497103 8,929 470,203 SH   SOLE   470,203 0 0
KEZAR LIFE SCIENCES INC COM 49372L100 3,696 708,000 SH   SOLE   708,000 0 0
KINIKSA PHARMACEUTICALS LTD COM CL A G5269C101 3,960 224,100 SH   SOLE   224,100 0 0
LUMOS PHARMA INC COM 55028X109 10,045 281,287 SH   SOLE   281,287 0 0
MACROGENICS INC COM 556099109 8,472 370,600 SH   SOLE   370,600 0 0
MAGENTA THERAPEUTICS INC COM 55910K108 375 47,804 SH   SOLE   47,804 0 0
MEI PHARMA INC COM NEW 55279B202 4,108 1,556,000 SH   SOLE   1,556,000 0 0
MERUS NV COM N5749R100 6,188 353,000 SH   SOLE   353,000 0 0
MYOVANT SCIENCES LTD COM G637AM102 10,487 682,500 SH   SOLE   682,500 0 0
NEOLEUKIN THERAPEUTICS INC COM 64049K104 19,547 1,386,300 SH   SOLE   1,386,300 0 0
OCULAR THERAPEUTIX INC COM 67576A100 134,758 6,510,000 SH   SOLE   6,510,000 0 0
OPTINOSE INC COM 68404V100 1,801 435,000 SH   SOLE   435,000 0 0
PRAXIS PRECISION MEDICINES INC COM 74006W108 3,489 63,416 SH   SOLE   63,416 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102 7,020 260,000 SH   SOLE   260,000 0 0
PROTARA THERAPEUTICS INC COM STK 74365U107 61,941 2,558,472 SH   SOLE   2,558,472 0 0
RHYTHM PHARMACEUTICALS INC COM 76243J105 3,419 115,000 SH   SOLE   115,000 0 0
SERES THERAPEUTICS COM 81750R102 9,804 335,312 SH   SOLE   335,312 0 0
SIERRA ONCOLOGY INC COM NEW 82640U404 1,208 75,379 SH   SOLE   75,379 0 0
SIO GENE THERAPIES INC COM 829399104 5,560 2,000,000 SH   SOLE   2,000,000 0 0
STEREOTAXIS INC COM NEW 85916J409 15,379 3,021,436 SH   SOLE   3,021,436 0 0
SUTRO BIOPHARMA INC COM 869367102 6,995 322,200 SH   SOLE   322,200 0 0
TELA BIO INC COM 872381108 5,490 365,000 SH   SOLE   365,000 0 0
TG THERAPEUTICS INC COM 88322Q108 20,158 387,500 SH   SOLE   387,500 0 0
TRACON PHARMACEUTICALS INC COM NEW 89237H209 29,465 2,518,371 SH   SOLE   2,518,371 0 0
TRICIDA INC COM 89610F101 6,761 959,000 SH   SOLE   959,000 0 0
VAXCYTE COM 92243G108 8,906 335,200 SH   SOLE   335,200 0 0
VERASTEM INC COM 92337C104 4,761 2,325,000 SH   SOLE   2,325,000 0 0
XOMA CORP DEL COM NEW 98419J206 20,079 455,000 SH   SOLE   455,000 0 0