The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
AbbVie Inc. Common 00287Y109 2,975 27,769 SH   DFND 2 27,769 0 0
AbbVie Inc. Common 00287Y109 536 5,000 SH   DFND 2 5,000 0 0
AC Immune SA Common H00263105 27 5,309 SH   DFND 2 5,309 0 0
ADMA Biologics, Inc. Common 000899104 42 21,457 SH   DFND 2 21,457 0 0
Alexion Pharamaceuticals, Inc. Common 015351109 1,648 10,545 SH   DFND 2 10,545 0 0
Alerian MLP Common 00162Q452 3 120 SH   DFND 1 120 0 0
Alimera Sciences, Inc. Common 016259202 338 80,194 SH   DFND 2 80,194 0 0
Alphabet Inc-Cl C Common 02079K107 9,811 5,600 SH   DFND 2 5,600 0 0
ALX Oncology. Inc Common 00166B105 276 3,200 SH   DFND 2 3,200 0 0
AllianceBernstein Holding PL Unit Ltd. Common 01881G106 51 1,500 SH   DFND 1 1,500 0 0
AllianceBernstein Holding PL Unit Ltd. Common 01881G106 1,655 49,000 SH   DFND 1 49,000 0 0
Apollo Global Management, Inc. Common 03768E105 14,694 300,000 SH   DFND 2 300,000 0 0
Apple Inc. Common 037833100 279 2,100 SH   DFND 1 2,100 0 0
AT&T Inc. Common 00206R102 59 2,050 SH   DFND 1 2,050 0 0
AT&T Inc. Common 00206R102 575 20,000 SH   DFND 1 20,000 0 0
Aurinia Pharmaceuticals Inc. Common 05156V102 2,455 177,540 SH   DFND 2 177,540 0 0
Avadel Pharmaceuticals plc Common 05337M104 581 86,916 SH   DFND 2 86,916 0 0
Axovant Gene Therapeutic, Ltd Common G0750W104 111 40,000 SH   DFND 2 40,000 0 0
Bank Nova Scotia Halifax Common 064149107 22 400 SH   DFND 1 400 0 0
BioCryst Pharmaceuticals, Inc. Common 09058V103 1,635 219,461 SH   DFND 2 219,461 0 0
BioDelivery Sciences International, Inc. Common 09060J106 1,555 370,230 SH   DFND 2 370,230 0 0
Bristol-Myers Squibb Company Common 110122108 3,251 52,409 SH   DFND 2 52,409 0 0
Bristol-Myers Squibb Company - CVR Common 110122157 45 64,720 SH   DFND 2 64,720 0 0
Calumet Specialty Products Partners, LP Common 131476103 8,216 2,625,000 SH   DFND 2 2,625,000 0 0
Calumet Specialty Products Partners, LP Common 131476103 63 20,000 SH   DFND 1 20,000 0 0
Canadian Natural Resources Inc. Common 136385101 440 18,285 SH   DFND 1 18,285 0 0
Canadian Natural Resources Inc. Common 136385101 96 4,000 SH   DFND 1 4,000 0 0
Capitol Investment Corp. V Common 14064F209 2,575 250,000 SH   DFND 2 250,000 0 0
Capitol Federal S&L Common 14057J101 73 5,800 SH   DFND 1 5,800 0 0
Check Cap Ltd. Common M2361E203 1 2,224 SH   DFND 2 2,224 0 0
Chemours Co. Common 163851108 18 720 SH   DFND 1 720 0 0
Chemours Co. Common 163851108 11 440 SH   DFND 1 440 0 0
Cidara Therapeutics, Inc. Common 171757107 831 415,308 SH   DFND 2 415,308 0 0
Coca Cola Common 191216100 318 5,800 SH   DFND 1 5,800 0 0
Coca Cola Common 191216100 417 7,600 SH   DFND 1 7,600 0 0
Coherus Biosciences, Inc. Common 19249H103 1,767 101,655 SH   DFND 2 101,655 0 0
Colony Cap Inc. Common 19626G108 7 1,466 SH   DFND 1 1,466 0 0
Conagra Brands Common 205887102 363 10,000 SH   DFND 1 10,000 0 0
Constellation Phamaceuticals, Inc. Common 210373106 950 33,000 SH   DFND 2 33,000 0 0
Corveta Inc. Common 22052L104 58 1,494 SH   DFND 1 1,494 0 0
Corveta Inc. Common 22052L104 428 11,051 SH   DFND 1 11,051 0 0
Cousins Properties Common 222795502 112 3,357 SH   DFND 1 3,357 0 0
CTI BioPharma Corp. Common 12648L601 64 20,000 SH   DFND 2 20,000 0 0
Danimer Scientific, Inc. Common 236272100 11,755 500,000 SH   DFND 2 500,000 0 0
DFP Healthcare Acquistions Corp. Common 23343Q209 11 1,000 SH   DFND 2 1,000 0 0
Dow Inc. Common 260557103 83 1,494 SH   DFND 1 1,494 0 0
Dow Inc. Common 260557103 590 10,624 SH   DFND 1 10,624 0 0
Dupont De Nemours Inc. Common 26614N102 106 1,494 SH   DFND 1 1,494 0 0
Dupont De Nemours Inc. Common 26614N102 755 10,624 SH   DFND 1 10,624 0 0
Eagle Materials Common 26969P108 23 228 SH   DFND 1 228 0 0
Eastern Bankshares Inc Common 27627N105 3,099 190,000 SH   DFND 2 190,000 0 0
Eastern Bankshares Inc Common 27627N105 163 10,000 SH   DFND 1 10,000 0 0
Editas Medicine Inc. Common 28106W103 421 6,000 SH   DFND 2 6,000 0 0
Eiger BioPharmaceuticals, Inc. Common 28249U105 3,626 295,035 SH   DFND 2 295,035 0 0
Eli Lilly Inc. Common 532457108 51 300 SH   DFND 1 300 0 0
FibroGen, Inc. Common 31572Q808 371 10,000 SH   DFND 2 10,000 0 0
FNB Corporation Common 302520101 85 8,905 SH   DFND 1 8,905 0 0
Fortress Trans & Infrastructure Inv. LLC Common 34960P101 16,422 700,000 SH   DFND 2 700,000 0 0
FS Bancorp Common 30263Y104 116 2,117 SH   DFND 1 2,117 0 0
FS Bancorp Common 30263Y104 80 1,460 SH   DFND 1 1,460 0 0
FS KKR Capital Corp. Common 302635206 5,796 350,000 SH   DFND 2 350,000 0 0
FS KKR Capital Corp. Common 302635206 266 16,050 SH   DFND 1 16,050 0 0
FS KKR Capital Corp. Common 302635206 482 29,125 SH   DFND 1 29,125 0 0
General Electric Common 369604103 38 3,480 SH   DFND 1 3,480 0 0
General Electric Common 369604103 13 1,200 SH   DFND 1 1,200 0 0
Gilead Sciences, Inc. Common 375558103 3,778 64,842 SH   DFND 2 64,842 0 0
Globus Medical, Inc. Common 379577208 302 4,631 SH   DFND 2 4,631 0 0
Heritage NOLA Bancorp Inc. Common 42727P108 110 9,000 SH   DFND 1 9,000 0 0
Horizon Aquistion Corporation Common G46049105 2,105 210,100 SH   DFND 2 210,100 0 0
Horizon Therapeutics Public Ltd. Company Common G46188101 3,117 42,614 SH   DFND 2 42,614 0 0
International Business Machines Common 459200101 539 4,284 SH   DFND 1 4,284 0 0
International Gaming Technologies Common G4863A108 1,694 100,000 SH   DFND 2 100,000 0 0
International Gaming Technologies Common G4863A108 127 7,500 SH   DFND 1 7,500 0 0
iPath Series B S&P 500 VIX Short-Term Fut Common 06746P621 3,358 200,000 SH   DFND 2 200,000 0 0
iShares Nasdaq Biotechnology ETF Common 464287556 151 1,000 SH   DFND 2 1,000 0 0
Johnson & Johnson Common 478160104 799 5,080 SH   DFND 1 5,080 0 0
Johnson & Johnson Common 478160104 157 1,000 SH   DFND 1 1,000 0 0
JP Morgan Chase Common 46625H100 1,811 14,250 SH   DFND 1 14,250 0 0
JP Morgan Chase Common 46625H100 727 5,720 SH   DFND 1 5,720 0 0
Kadmon Holdings, Inc. Common 48283N106 2,913 702,000 SH   DFND 2 702,000 0 0
Kimberly Clark Corporation Common 494368103 809 6,000 SH   DFND 1 6,000 0 0
Kennedy-Wilson Holdings, Inc. Common 489398107 3,757 210,000 SH   DFND 2 210,000 0 0
KKR & Co. Inc. Common 48251W104 4,049 100,000 SH   DFND 2 100,000 0 0
Leap Therapeutics, Inc. Common 52187K101 22 9,700 SH   DFND 2 9,700 0 0
Legacy Housing Corporation Common 52472M101 76 5,000 SH   DFND 1 5,000 0 0
Legacy Housing Corporation Common 52472M101 60 4,000 SH   DFND 1 4,000 0 0
Ligand Pharmaceuticals Incorporated Common 53220K504 23,589 237,198 SH   DFND 2 237,198 0 0
Ligand Pharmaceuticals Incorporated Common 53220K504 895 9,000 SH   DFND 1 9,000 0 0
Ligand Pharmaceuticals Incorporated Common 53220K504 183 1,843 SH   DFND 1 1,843 0 0
LKQ Corporation Common 501889208 4,229 120,000 SH   DFND 2 120,000 0 0
Longview Aquisition Corp. Common 543195101 364 18,380 SH   DFND 2 18,380 0 0
Marinus Pharmaceutical, Inc. Common 56854Q200 305 25,000 SH   DFND 2 25,000 0 0
Macquarie Infrastructure Corporation Common 55608B105 124 3,300 SH   DFND 1 3,300 0 0
Macquarie Infrastructure Corporation Common 55608B105 370 9,850 SH   DFND 1 9,850 0 0
Medtronics Common G5960L103 123 1,050 SH   DFND 1 1,050 0 0
Merck & Co. Inc. Common 58993Y105 65 800 SH   DFND 1 800 0 0
Merck & Co. Inc. Common 58993Y105 41 500 SH   DFND 1 500 0 0
Microsoft Corporation Common 594918104 89 400 SH   DFND 1 400 0 0
Microsoft Corporation Common 594918104 222 1,000 SH   DFND 1 1,000 0 0
Midwest Holdings Inc. Common 59833J206 7,705 143,621 SH   DFND 2 143,621 0 0
Mondelez Int'l Inc. Common 609207105 170 2,900 SH   DFND 1 2,900 0 0
Mondelez Int'l Inc. Common 609207105 760 13,000 SH   DFND 1 13,000 0 0
MPLX LP Common 55336V100 2,165 100,000 SH   DFND 2 100,000 0 0
Occidental Pete Corp Common 674599105 29 1,700 SH   DFND 1 1,700 0 0
Occidental Pete Corp Common 674599105 22 1,273 SH   DFND 1 1,273 0 0
Occidental Pete Corp Wts exp 8/3/27 Common 674599162 5 212 SH   DFND 1 212 0 0
Occidental Pete Corp Wts exp 8/3/27 Common 674599162 3 158 SH   DFND 1 158 0 0
Peoples United Financial Common 712704105 19 1,500 SH   DFND 1 1,500 0 0
Pfizer Inc. Common 717081103 1,137 30,900 SH   DFND 1 30,900 0 0
Pfizer Inc. Common 717081103 3,276 89,000 SH   DFND 1 89,000 0 0
Protara Therapeutics, Inc. Common 74365U107 348 14,369 SH   DFND 2 14,369 0 0
Quotient Technology Inc. Common 749119103 471 50,000 SH   DFND 2 50,000 0 0
Radius Health Inc. Common 750469207 447 25,034 SH   DFND 2 25,034 0 0
Reinvent Technology Partners Common G7483N129 2,037 176,226 SH   DFND 2 176,226 0 0
Relmada Therapeutics, Inc. Common 75955J402 96 3,000 SH   DFND 2 3,000 0 0
RMR Group Inc. Common 74967R106 1 16 SH   DFND 1 16 0 0
Ryman Hospitality Ppty Inc. Common 78377T107 27 400 SH   DFND 1 400 0 0
Ryman Hospitality Ppty Inc. Common 78377T107 813 12,000 SH   DFND 1 12,000 0 0
Sculptor Capital Management Common 811246107 3 200 SH   DFND 1 200 0 0
Service Ppty Trust Common 81761L102 11 1,000 SH   DFND 1 1,000 0 0
South Street Corporation Common 840441109 112 1,548 SH   DFND 1 1,548 0 0
South Street Corporation Common 840441109 39 534 SH   DFND 1 534 0 0
Starwood Ppty Common 85571B105 8 400 SH   DFND 1 400 0 0
Strongbridge Biopharma PLC Common BY25XL9US 647 266,194 SH   DFND 2 266,194 0 0
TG Therapeutics Inc. Common 88322Q108 2,641 50,773 SH   DFND 2 50,773 0 0
Trillium Therapeutics Inc. Common 89620X506 2,570 174,699 SH   DFND 2 174,699 0 0
The Kraft Heinz Company Common 500754106 105 3,035 SH   DFND 1 3,035 0 0
The Kraft Heinz Company Common 500754106 42 1,199 SH   DFND 1 1,199 0 0
Total SA Common 89151E109 99 2,360 SH   DFND 1 2,360 0 0
Total SA Common 89151E109 21 500 SH   DFND 1 500 0 0
uniQure N.V. Common N90064101 1,265 35,000 SH   DFND 2 35,000 0 0
Upland Software, Inc. Common 91544A109 18,654 406,500 SH   DFND 2 406,500 0 0
Valley National Bancorp Common 919794107 90 9,280 SH   DFND 1 9,280 0 0
Valley National Bancorp Common 919794107 31 3,200 SH   DFND 1 3,200 0 0
Vapotherm, Inc. Common 922107107 1,316 49,000 SH   DFND 2 49,000 0 0
Verizon Communications Common 92343V104 78 1,320 SH   DFND 1 1,320 0 0
Verizon Communications Common 92343V104 998 16,991 SH   DFND 1 16,991 0 0
Verrica Pharmaceuticals, Inc. Common 92511W108 881 76,585 SH   DFND 2 76,585 0 0
Viatris Inc. Common 92556V106 5 80 SH   DFND 1 80 0 0
Viking Therapeutics, Inc. Common 92686J106 1,228 218,102 SH   DFND 2 218,102 0 0
WABTEC Common 929740108 1 17 SH   DFND 1 17 0 0
WABTEC Common 929740108 0 6 SH   DFND 1 6 0 0
WP Carey Common 92936U109 423 6,000 SH   DFND 1 6,000 0 0
Xenon Pharmaceuticals Inc. Common 98420N105 3,076 200,000 SH   DFND 2 200,000 0 0
Zogenix, Inc. Common 98978L204 2,253 112,707 SH   DFND 2 112,707 0 0