The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107 90,410 11,329,581 SH   SOLE   11,329,581 0 0
ADVERUM BIOTECHNOLOGIES INC COM 00773U108 96,932 9,410,860 SH   SOLE   9,410,860 0 0
AKOUOS INC COM 00973J101 52,172 2,281,249 SH   SOLE   2,281,249 0 0
ALECTOR INC COM 014442107 38,124 3,618,748 SH   SOLE   3,618,748 0 0
ARDELYX INC COM 039697107 32,870 6,260,904 SH   SOLE   6,260,904 0 0
ARCUTIS BIOTHERAPEUTICS INC COM 03969K108 34,140 1,165,184 SH   SOLE   1,165,184 0 0
ARVINAS INC COM 04335A105 86,717 3,672,872 SH   SOLE   3,672,872 0 0
ARYA SCIENCES ACQUISITION CO COM CL A G3166W106 10,815 1,000,000 SH   SOLE   1,000,000 0 0
ARYA SCIENCES ACQUISITION CORP UNIT 06/09/2027 G31655114 7,700 700,000 SH   SOLE   700,000 0 0
ASCENDIS PHARMA A S SPONSORED ADR 04351P101 911,991 5,909,742 SH   SOLE   5,909,742 0 0
AXSOME THERAPEUTICS INC COM 05464T104 145,003 2,035,132 SH   SOLE   2,035,132 0 0
BCTG ACQUISITION CORP COM 05492W103 12,950 1,250,000 SH   SOLE   1,250,000 0 0
BLACK DIAMOND THERAPEUTICS INC COM 09203E105 78,293 2,589,904 SH   SOLE   2,589,904 0 0
CHEMOCENTRYX INC COM 16383L106 264,515 4,826,910 SH   SOLE   4,826,910 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 5,236 353,072 SH   SOLE   353,072 0 0
CONCERT PHARMACEUTICALS INC COM 206022105 18,250 1,858,474 SH   SOLE   1,858,474 0 0
CARDIFF ONCOLOGY INC COM 14147L108 46,685 3,290,000 SH   SOLE   3,290,000 0 0
CRINETICS PHARMACEUTICALS INC COM 22663K107 36,491 2,328,698 SH   SOLE   2,328,698 0 0
DYNE THERAPEUTICS INC COM 26818M108 56,634 2,805,045 SH   SOLE   2,805,045 0 0
EIDOS THERAPEUTICS INC COM 28249H104 109,310 2,163,271 SH   SOLE   2,163,271 0 0
ESSA PHARMA INC COM NEW 29668H708 3,246 470,428 SH   SOLE   470,428 0 0
89BIO INC COM 282559103 121,531 4,736,214 SH   SOLE   4,736,214 0 0
FORMA THERAPEUTICS HLDGS INC SHS 34633R104 449,141 9,011,651 SH   SOLE   9,011,651 0 0
FS DEV CORP COM CL A 303020101 11,198 1,000,000 SH   SOLE   1,000,000 0 0
GERON CORP COM 374163103 52,420 30,126,299 SH   SOLE   30,126,299 0 0
GALERA THERAPEUTICS INC COM 36338D108 7,459 825,118 SH   SOLE   825,118 0 0
HEALTH SCIENCES ACQ CORP 2 ORD SHS G4411D109 6,875 625,000 SH   SOLE   625,000 0 0
IGM BIOSCIENCES INC COM 449585108 72,535 982,723 SH   SOLE   982,723 0 0
IMMUNOGEN INC COM 45253H101 25,346 7,040,485 SH   SOLE   7,040,485 0 0
IMARA INC COM 45249V107 5,080 249,739 SH   SOLE   249,739 0 0
INHIBRX INC COM 45720L107 38,322 2,129,003 SH   SOLE   2,129,003 0 0
INOZYME PHARMA INC COM 45790W108 52,676 2,003,653 SH   SOLE   2,003,653 0 0
ITEOS THERAPEUTICS INC COM 46565G104 108,974 4,417,258 SH   SOLE   4,417,258 0 0
KALA PHARMACEUTICALS INC COM 483119103 81,560 10,874,613 SH   SOLE   10,874,613 0 0
KEROS THERAPEUTICS INC COM 492327101 72,319 1,875,000 SH   SOLE   1,875,000 0 0
LEGEND BIOTECH CORP SPONSORED ADS 52490G102 74,344 2,408,292 SH   SOLE   2,408,292 0 0
LYRA THERAPEUTICS INC COM 55234L105 9,252 815,849 SH   SOLE   815,849 0 0
LARIMAR THERAPEUTICS INC COM 517125100 22,985 1,515,151 SH   SOLE   1,515,151 0 0
SERES THERAPEUTICS INC COM 81750R102 134,473 4,750,000 SH   SOLE   4,750,000 0 0
MACROGENICS INC COM 556099109 110,212 4,375,217 SH   SOLE   4,375,217 0 0
MILESTONE PHARMACEUTICALS INC COM 59935V107 17,706 2,418,798 SH   SOLE   2,418,798 0 0
NKARTA INC COM 65487U108 168,490 5,605,129 SH   SOLE   5,605,129 0 0
NOVAVAX INC COM NEW 670002401 129,869 1,198,602 SH   SOLE   1,198,602 0 0
OCULAR THERAPEUTIX INC COM 67576A100 20,755 2,727,272 SH   SOLE   2,727,272 0 0
ORCHARD THERAPEUTICS PLC ADS 68570P101 50,616 12,315,213 SH   SOLE   12,315,213 0 0
OVID THERAPEUTICS INC COM 690469101 1,636 285,000 SH   SOLE   285,000 0 0
PANDION THERAPEUTICS INC COM 698340106 20,284 1,770,023 SH   SOLE   1,770,023 0 0
PASSAGE BIO INC COM 702712100 4,230 322,630 SH   SOLE   322,630 0 0
VAXCYTE INC COM 92243G108 260,915 5,283,818 SH   SOLE   5,283,818 0 0
PHATHOM PHARMACEUTICALS INC COM 71722W107 140,263 3,825,008 SH   SOLE   3,825,008 0 0
PMV PHARMACEUTICALS INC COM 69353Y103 60,714 1,710,265 SH   SOLE   1,710,265 0 0
PREVAIL THERAPEUTICS INC COM 74140Y101 19,500 1,915,568 SH   SOLE   1,915,568 0 0
RELAY THERAPEUTICS INC COM 75943R102 42,590 1,000,000 SH   SOLE   1,000,000 0 0
RELMADA THERAPEUTICS INC COM 75955J402 29,392 781,290 SH   SOLE   781,290 0 0
REPARE THERAPEUTICS INC COM 760273102 12,585 409,000 SH   SOLE   409,000 0 0
RETROPHIN INC COM 761299106 85,575 4,635,687 SH   SOLE   4,635,687 0 0
RHYTHM PHARMACEUTICALS INC COM 76243J105 111,393 5,140,408 SH   SOLE   5,140,408 0 0
SCPHARMACEUTICALS INC COM 810648105 26,217 3,518,998 SH   SOLE   3,518,998 0 0
SOLID BIOSCIENCES INC COM 83422E105 9,279 4,571,164 SH   SOLE   4,571,164 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105 15,100 1,023,067 SH   SOLE   1,023,067 0 0
SUTRO BIOPHARMA INC COM 869367102 21,288 2,118,212 SH   SOLE   2,118,212 0 0
SATSUMA PHARMACEUTICALS INC COM 80405P107 18,212 4,681,858 SH   SOLE   4,681,858 0 0
TG THERAPEUTICS INC COM 88322Q108 236,180 8,825,849 SH   SOLE   8,825,849 0 0
TRILLIUM THERAPEUTICS INC COM NEW 89620X506 87,572 6,162,694 SH   SOLE   6,162,694 0 0
VERASTEM INC COM 92337C104 9,760 8,066,171 SH   SOLE   8,066,171 0 0
VERONA PHARMA PLC SPONSORED ADS 925050106 31,824 5,100,000 SH   SOLE   5,100,000 0 0
VAXART INC COM NEW 92243A200 71,893 10,810,937 SH   SOLE   10,810,937 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105 66,012 7,775,207 SH   SOLE   7,775,207 0 0
X4 PHARMACEUTICALS INC COM 98420X103 3,788 559,494 SH   SOLE   559,494 0 0
ZOGENIX INC COM NEW 98978L204 98,407 5,488,424 SH   SOLE   5,488,424 0 0