The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABBVIE INC COM 00287Y109 133,382 1,522,800 SH   SOLE   1,522,800 0 0
AC IMMUNE SA SHS H00263105 7,564 1,550,000 SH   SOLE   1,550,000 0 0
ACCOLADE INC COM 00437E102 1,555 40,000 SH   SOLE   40,000 0 0
ADAPTIMMUNE THERAPEUTICS PLS SPONDS ADR 00653A107 16,636 2,084,700 SH   SOLE   2,084,700 0 0
AKEBIA THERAPEUTICS INC COM 00972D105 18,383 7,324,000 SH   SOLE   7,324,000 0 0
ALDEYRA THERAPEUTICS INC COM 01438T106 10,596 1,430,000 SH   SOLE   1,430,000 0 0
ALPINE IMMUNE SCIENCES INC COM 02083G100 7,120 810,000 SH   SOLE   810,000 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206 18,970 4,506,000 SH   SOLE   4,506,000 0 0
AMERICAN WELL CORP CL A 03044L105 1,482 50,000 SH   SOLE   50,000 0 0
ANIKA THERAPEUTICS INC COM 035255108 21,294 601,700 SH   SOLE   601,700 0 0
ANNEXON INC COM 03589W102 1,136 37,570 SH   SOLE   37,570 0 0
ANTHEM INC COM 036752103 47,379 176,400 SH   SOLE   176,400 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106 18,805 623,300 SH   SOLE   623,300 0 0
ARVINAS INC COM 04335A105 31,833 1,348,300 SH   SOLE   1,348,300 0 0
ARYA SCIENCES ACQUISITION CO COM CL A G31655114 5,408 500,000 SH   SOLE   500,000 0 0
ATHIRA PHARMA INC COM 04746L104 18,946 1,026,342 SH   SOLE   1,026,342 0 0
AURINIA PHARMACEUTICALS INC COM 05156V102 52,511 3,564,900 SH   SOLE   3,564,900 0 0
AVANTOR INC COM 05352A100 102,608 4,562,400 SH   SOLE   4,562,400 0 0
AXSOME THERAPEUTICS INC COM 05464T104 8,408 118,000 SH   SOLE   118,000 0 0
BAXTER INTL INC COM 071813109 49,860 620,000 SH   SOLE   620,000 0 0
BCTG ACQUISITION CORP COM 05492W103 3,108 300,000 SH   SOLE   300,000 0 0
BERKELEY LTS INC COM 084310101 1,909 25,000 SH   SOLE   25,000 0 0
BIOGEN INC COM 09062X103 89,388 315,100 SH   SOLE   315,100 0 0
BIOGEN INC COM 09062X903 60,736 214,100 SH Call SOLE   214,100 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 83,486 1,284,200 SH   SOLE   1,284,200 0 0
BIONTECH SE SPONSORED ADS 09075V102 14,261 206,000 SH   SOLE   206,000 0 0
BIOXCEL THERAPEUTICS INC COM 09075P105 23,328 538,000 SH   SOLE   538,000 0 0
BOSTON SCIENTIFIC CORPORATION COM 101137107 36,953 967,100 SH   SOLE   967,100 0 0
BRISTOL-MYERS SQUIBB CO RIGHT 99/99/9999 110122157 51,041 22,684,932 SH   SOLE   22,684,932 0 0
CATALENT INC COM 148806102 27,248 318,100 SH   SOLE   318,100 0 0
CHANGE HEALTHCARE INC COM 15912K100 36,674 2,527,500 SH   SOLE   2,527,500 0 0
CLOVIS ONCOLOGY INC COM 189464100 5,830 1,000,000 SH   SOLE   1,000,000 0 0
COLLEGIUM PHARMACEUTICAL INC COM 19459J104 20,828 1,000,400 SH   SOLE   1,000,400 0 0
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201 8,748 2,025,000 SH   SOLE   2,025,000 0 0
ESSA PHARMA INC COM NEW 29668H708 14,406 2,087,800 SH   SOLE   2,087,800 0 0
EXELIXIS INC COM 30161Q104 18,807 769,200 SH   SOLE   769,200 0 0
HARPOON THERAPEUTICS INC COM 41358P106 19,907 1,171,700 SH   SOLE   1,171,700 0 0
HEALTH SCIENCES ACQ CORP 2 ORD SHS G4411D109 4,400 400,000 SH   SOLE   400,000 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 72,258 930,200 SH   SOLE   930,200 0 0
HUMANA INC COM 444859102 21,315 51,500 SH   SOLE   51,500 0 0
I MAB SPONSORED ADS 44975P103 63,020 1,340,000 SH   SOLE   1,340,000 0 0
IDEAYA BIOSCIENCES INC COM 45166A102 13,198 1,050,800 SH   SOLE   1,050,800 0 0
INOZYME PHARMA INC COM 45790W108 1,626 61,855 SH   SOLE   61,855 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100 26,303 799,000 SH   SOLE   799,000 0 0
ITEOS THERAPEUTICS INC COM 46565G104 8,141 330,000 SH   SOLE   330,000 0 0
KADMON HLDGS INC COM 48283N106 35,398 9,030,000 SH   SOLE   9,030,000 0 0
MEDTRONIC PLC SHS G5960L103 18,810 181,000 SH   SOLE   181,000 0 0
MERCK & CO. INC COM 58933Y105 94,920 1,144,300 SH   SOLE   1,144,300 0 0
MERSANA THERAPEUTICS INC COM 59045L106 14,103 757,400 SH   SOLE   757,400 0 0
MIRATI THERAPEUTICS INC COM 60468T105 45,664 275,000 SH   SOLE   275,000 0 0
NATERA INC COM 632307104 36,366 503,400 SH   SOLE   503,400 0 0
NURIX THERAPEUTICS INC COM 67080M103 1,746 50,000 SH   SOLE   50,000 0 0
OAK STR HEALTH INC COM 67181A107 5,344 100,000 SH   SOLE   100,000 0 0
OUTSET MED INC COM 690145107 5,000 100,000 SH   SOLE   100,000 0 0
PANACEA ACQUISITION CORP UNIT 99/99/9999 698102209 3,600 300,000 SH   SOLE   300,000 0 0
PFIZER INC COM 717081903 238,550 6,500,000 SH Call SOLE   6,500,000 0 0
PMV PHARMACEUTICALS INC COM 69353Y103 5,325 150,000 SH   SOLE   150,000 0 0
QUEST DIAGNOSTICS INC COM 74834L100 46,025 402,000 SH   SOLE   402,000 0 0
QUIDEL CORP COM 74838J101 38,804 176,879 SH   SOLE   176,879 0 0
RELAY THERAPEUTICS INC COM 75943R102 1,278 30,000 SH   SOLE   30,000 0 0
SEATTLE GENETICS INC COM 812578102 103,931 531,100 SH   SOLE   531,100 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105 27,367 1,854,100 SH   SOLE   1,854,100 0 0
TAYSHA GENE THERAPIES INC COM SHS 877619106 8,781 392,000 SH   SOLE   392,000 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102 52,232 118,300 SH   SOLE   118,300 0 0
TRILLIUM THERAPEUTICS INC COM NEW 89620X506 24,811 1,746,000 SH   SOLE   1,746,000 0 0
VESPER HEALTHCARE ACQSTN COR UNIT 99/99/9999 92538T203 6,156 600,000 SH   SOLE   600,000 0 0
ZENTALIS PHARMACEUTICALS INC COM 98943L107 29,556 904,119 SH   SOLE   904,119 0 0
ZYMEWORKS INC COM 98985W102 11,398 244,700 SH   SOLE   244,700 0 0