The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
1LIFE HEALTHCARE INC COM 68269G107 94,856 3,344,694 SH   SOLE   3,344,694 0 0
ADC THERAPEUTICS SA SHS H0036K147 209,589 6,353,094 SH   SOLE   6,353,094 0 0
AKERO THERAPEUTICS INC COM 00973Y108 71,936 2,336,357 SH   SOLE   2,336,357 0 0
ALLAKOS INC COM 01671P100 197,562 2,425,560 SH   SOLE   2,425,560 0 0
ALLOVIR INC COM 019818103 64,168 2,333,390 SH   SOLE   2,333,390 0 0
ALX ONCOLOGY HLDGS INC COM 00166B105 15,375 407,400 SH   SOLE   407,400 0 0
AMEDISYS INC COM 023436108 33,143 140,180 SH   SOLE   140,180 0 0
AMICUS THERAPEUTICS INC COM 03152W109 325,830 23,075,807 SH   SOLE   23,075,807 0 0
ANNEXON INC COM 03589W102 104,055 3,442,122 SH   SOLE   3,442,122 0 0
APREA THERAPEUTICS INC COM 03836J102 54,585 2,268,718 SH   SOLE   2,268,718 0 0
ARDELYX INC COM 039697107 18,449 3,514,100 SH   SOLE   3,514,100 0 0
ARGENX SE SPONSORED ADR 04016X101 259,493 988,468 SH   SOLE   988,468 0 0
ATARA BIOTHERAPEUTICS INC COM 046513107 89,928 6,938,870 SH   SOLE   6,938,870 0 0
ATRECA INC CL A COM 04965G109 35,598 2,548,168 SH   SOLE   2,548,168 0 0
AVITA THERAPEUTICS INC COM 05380C102 44,774 1,779,586 SH   SOLE   1,779,586 0 0
AXONICS MODULATION TECHNOLOG COM 05465P101 37,827 741,129 SH   SOLE   741,129 0 0
AYALA PHARMACEUTICALS INC COM 05465V108 7,853 666,666 SH   SOLE   666,666 0 0
BEAM THERAPEUTICS INC COM 07373V105 81,917 3,327,262 SH   SOLE   3,327,262 0 0
BIOGEN INC COM 09062X103 92,890 327,447 SH   SOLE   327,447 0 0
BIONTECH SE SPONSORED ADS 09075V102 85,544 1,235,645 SH   SOLE   1,235,645 0 0
BOSTON SCIENTIFIC CORP COM 101137107 54,336 1,422,049 SH   SOLE   1,422,049 0 0
CABALETTA BIO INC COM 12674W109 15,031 1,386,584 SH   SOLE   1,386,584 0 0
CASTLIGHT HEALTH INC CL B 14862Q100 12 10,229 SH   SOLE   10,229 0 0
CATALENT INC COM 148806102 28,218 329,419 SH   SOLE   329,419 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 29,500 1,989,200 SH   SOLE   1,989,200 0 0
CIGNA CORP NEW COM 125523100 67,204 396,693 SH   SOLE   396,693 0 0
CYMABAY THERAPEUTICS INC COM 23257D103 12,447 1,719,247 SH   SOLE   1,719,247 0 0
CYTOSORBENTS CORP COM NEW 23283X206 16,757 2,101,131 SH   SOLE   2,101,131 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 244,953 4,774,918 SH   SOLE   4,774,918 0 0
DEXCOM INC COM 252131107 34,385 83,412 SH   SOLE   83,412 0 0
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201 11,010 2,548,620 SH   SOLE   2,548,620 0 0
EIDOS THERAPEUTICS INC COM 28249H104 23,557 466,205 SH   SOLE   466,205 0 0
EPIZYME INC COM 29428V104 99,158 8,311,633 SH   SOLE   8,311,633 0 0
FATE THERAPEUTICS INC COM 31189P102 504,811 12,629,737 SH   SOLE   12,629,737 0 0
FS DEV CORP COM CL A 303020101 11,200 1,000,000 SH   SOLE   1,000,000 0 0
GENMARK DIAGNOSTICS INC COM 372309104 66,933 4,713,600 SH   SOLE   4,713,600 0 0
GILEAD SCIENCES INC COM 375558103 181,353 2,869,962 SH   SOLE   2,869,962 0 0
GOODRX HLDGS INC COM CL A 38246G108 11,120 200,000 SH   SOLE   200,000 0 0
GRITSTONE ONCOLOGY INC COM 39868T105 8,108 3,059,794 SH   SOLE   3,059,794 0 0
HOOKIPA PHARMA INC COM 43906K100 17,452 1,842,902 SH   SOLE   1,842,902 0 0
ICU MED INC COM 44930G107 28,886 158,054 SH   SOLE   158,054 0 0
IGM BIOSCIENCES INC COM 449585108 252,833 3,425,455 SH   SOLE   3,425,455 0 0
IMMATICS N.V SHS N44445109 22,599 2,130,000 SH   SOLE   2,130,000 0 0
IMMUNOGEN INC COM 45253H101 37,720 10,477,879 SH   SOLE   10,477,879 0 0
IMMUNOMEDICS INC COM 452907108 275,066 3,234,934 SH   SOLE   3,234,934 0 0
IMMUNOVANT INC COM 45258J102 4,256 120,940 SH   SOLE   120,940 0 0
INVITAE CORP COM 46185L103 8,453 195,003 SH   SOLE   195,003 0 0
ITAMAR MED LTD SPONSORED ADS 465437101 12,713 625,000 SH   SOLE   625,000 0 0
KRYSTAL BIOTECH INC COM 501147102 64,659 1,501,945 SH   SOLE   1,501,945 0 0
KYMERA THERAPEUTICS INC COM 501575104 88,292 2,732,660 SH   SOLE   2,732,660 0 0
LUMINEX CORP DEL COM 55027E102 23,995 914,107 SH   SOLE   914,107 0 0
NEOLEUKIN THERAPEUTICS INC COM 64049K104 50,072 4,172,686 SH   SOLE   4,172,686 0 0
NEVRO CORP COM 64157F103 64,024 459,609 SH   SOLE   459,609 0 0
NURIX THERAPEUTICS INC COM 67080M103 90,542 2,593,570 SH   SOLE   2,593,570 0 0
OAK STR HEALTH INC COM 67181A107 141,745 2,652,411 SH   SOLE   2,652,411 0 0
ODONATE THERAPEUTICS INC COM 676079106 338 25,162 SH   SOLE   25,162 0 0
OUTSET MED INC COM 690145107 3,500 70,000 SH   SOLE   70,000 0 0
OVID THERAPEUTICS INC COM 690469101 700 121,950 SH   SOLE   121,950 0 0
PANDION THERAPEUTICS INC COM 698340106 12,831 1,119,600 SH   SOLE   1,119,600 0 0
PLIANT THERAPEUTICS INC COM 729139105 76,823 3,391,757 SH   SOLE   3,391,757 0 0
PPD INC COM 69355F102 31,556 853,092 SH   SOLE   853,092 0 0
PRA HEALTH SCIENCES INC COM 69354M108 28,194 277,936 SH   SOLE   277,936 0 0
PROFOUND MED CORP COM NEW 74319B502 14,553 825,000 SH   SOLE   825,000 0 0
REGENXBIO INC COM 75901B107 61,319 2,228,166 SH   SOLE   2,228,166 0 0
REPARE THERAPEUTICS INC COM 760273102 74,001 2,404,974 SH   SOLE   2,404,974 0 0
REPLIMUNE GROUP INC COM 76029N106 76,680 3,330,999 SH   SOLE   3,330,999 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 1,787 744,582 SH   SOLE   744,582 0 0
SANOFI SPONSORED ADR 80105N105 87,449 1,743,048 SH   SOLE   1,743,048 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103 51,317 2,900,889 SH   SOLE   2,900,889 0 0
SELECTQUOTE INC COM 816307300 27,445 1,355,304 SH   SOLE   1,355,304 0 0
STEREOTAXIS INC COM NEW 85916J409 11,110 3,103,327 SH   SOLE   3,103,327 0 0
STOKE THERAPEUTICS INC COM 86150R107 85,383 2,549,506 SH   SOLE   2,549,506 0 0
SYROS PHARMACEUTICALS INC COM 87184Q107 1,877 212,291 SH   SOLE   212,291 0 0
TCR2 THERAPEUTICS INC COM 87808K106 56,760 2,793,288 SH   SOLE   2,793,288 0 0
TRICIDA INC COM 89610F101 25,897 2,858,415 SH   SOLE   2,858,415 0 0
UNIQURE NV SHS N90064101 41,575 1,128,827 SH   SOLE   1,128,827 0 0
VAPOTHERM INC COM 922107107 725 25,000 SH   SOLE   25,000 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105 1,389 163,619 SH   SOLE   163,619 0 0
XERIS PHARMACEUTICALS INC COM 98422L107 14,217 2,397,441 SH   SOLE   2,397,441 0 0
ZENTALIS PHARMACEUTICALS INC COM 98943L107 79,515 2,432,408 SH   SOLE   2,432,408 0 0
ZYMEWORKS INC COM 98985W102 51,313 1,101,600 SH   SOLE   1,101,600 0 0