The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ADIENT PLC ORD SHS G0084W101 20,859 1,203,588 SH   DFND   1,203,588 0 0
ADMA BIOLOGICS INC COM 000899104 4,780 2,000,000 SH   DFND   2,000,000 0 0
AFFIMED N V COM N01045108 12,373 3,650,000 SH   DFND   3,650,000 0 0
ALDEYRA THERAPEUTICS INC COM 01438T106 1,223 165,000 SH   DFND   165,000 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 15,288 105,000 SH   DFND   105,000 0 0
ALTRIA GROUP INC COM 02209S103 17,537 453,860 SH   DFND   453,860 0 0
AMAZON COM INC COM 023135106 37,785 12,000 SH   DFND   12,000 0 0
AMCI ACQUISITION CORP *W EXP 05/20/202 00165R119 136 200,000 SH   DFND   200,000 0 0
ANGI HOMESERVICES INC COM CL A 00183L102 12,756 1,149,673 SH   DFND   1,149,673 0 0
APPLIED GENETIC TECHNOLOGIES COM 03820J100 1,770 364,299 SH   DFND   364,299 0 0
APTOSE BIOSCIENCES INC COM NEW 03835T200 7,001 1,166,887 SH   DFND   1,166,887 0 0
ARCTURUS THERAPEUTICS HLDGS COM 03969T109 723 16,855 SH   DFND   16,855 0 0
ARDELYX INC COM 039697107 11,911 2,268,798 SH   DFND   2,268,798 0 0
ARYA SCIENCES ACQUISITION CO COM CL A G3166W106 4,326 400,000 SH   DFND   400,000 0 0
AT HOME GROUP INC COM 04650Y100 6,104 410,793 SH   DFND   410,793 0 0
ATARA BIOTHERAPEUTICS INC COM 046513107 2,862 220,848 SH   DFND   220,848 0 0
BARRICK GOLD CORP COM 067901108 15,783 561,477 SH   DFND   561,477 0 0
BERKSHIRE HATHAWAY INC DEL CL B NEW 084670702 10,647 50,000 SH Put DFND   50,000 0 0
BIG ROCK PARTNERS ACQUISI CO *W EXP 12/01/202 089482111 21 82,500 SH   DFND   82,500 0 0
BIG ROCK PARTNERS ACQUISI CO RIGHT 12/01/2022 089482129 34 165,000 SH   DFND   165,000 0 0
BIOMX INC *W EXP 10/16/202 09090D111 59 83,084 SH   DFND   83,084 0 0
BONANZA CREEK ENERGY INC COM NEW 097793400 235 12,500 SH   DFND   12,500 0 0
BROOGE ENERGY LTD *W EXP 12/20/202 G1611B115 161 321,684 SH   DFND   321,684 0 0
CAPITAL ONE FINL CORP COM 14040H105 35,328 491,617 SH   DFND   491,617 0 0
CARDLYTICS INC COM 14161W105 70,625 1,000,774 SH   DFND   1,000,774 0 0
CARVANA CO CL A 146869102 167,294 750,000 SH   DFND   750,000 0 0
CELLECTIS S A SPON ADS 15117K103 3,701 200,000 SH   DFND   200,000 0 0
ARYA SCIENCES ACQUISITION CO *W EXP 06/09/202 G31655106 421 233,333 SH   DFND   233,333 0 0
ARYA SCIENCES ACQUISITION CO COM CL A G31655122 7,315 700,000 SH   DFND   700,000 0 0
CHIMERIX INC COM 16934W106 822 330,061 SH   DFND   330,061 0 0
CIMPRESS PLC SHS EURO G2143T103 6,572 87,436 SH   DFND   87,436 0 0
CM LIFE SCIENCES INC UNIT 09/01/2025 18978W208 7,853 750,000 SH   DFND   750,000 0 0
COCA-COLA CO COM 191216100 9,874 200,000 SH Put DFND   200,000 0 0
CONTRAFECT CORP COM NEW 212326300 3,168 600,000 SH   DFND   600,000 0 0
CRESUD S A C I F Y A SPONSORED ADR 226406106 3,876 1,379,039 SH   DFND   1,379,039 0 0
CUE BIOPHARMA INC COM 22978P106 4,816 320,000 SH   DFND   320,000 0 0
DHT HOLDINGS INC SHS NEW Y2065G121 7,307 1,416,100 SH   DFND   1,416,100 0 0
DIAGEO PLC SPON ADR NEW 25243Q205 30,010 218,000 SH   DFND   218,000 0 0
DIAMOND S SHIPPING INC COM Y20676105 1,442 210,000 SH   DFND   210,000 0 0
DIANA SHIPPING INC COM Y2066G104 131 93,229 SH   DFND   93,229 0 0
DIRTT ENVIRONMENTAL SOLUTION COM 25490H106 11,043 7,069,735 SH   DFND   7,069,735 0 0
EIGER BIOPHARMACEUTICALS INC COM 28249U105 21,350 2,622,914 SH   DFND   2,622,914 0 0
ENERGY RECOVERY INC COM 29270J100 4,264 520,000 SH   DFND   520,000 0 0
ENOVA INTL INC COM 29357K103 34,737 2,119,423 SH   DFND   2,119,423 0 0
EURONAV NV SHS B38564108 2,402 272,000 SH   DFND   272,000 0 0
FALCON MINERALS CORP *W EXP 07/21/202 30607B208 9 115,020 SH   DFND   115,020 0 0
FATE THERAPEUTICS INC COM 31189P102 8,993 225,000 SH   DFND   225,000 0 0
FENNEC PHARMACEUTICALS INC COM 31447P100 6,727 1,110,000 SH   DFND   1,110,000 0 0
FIRSTENERGY CORP COM 337932107 64,207 2,236,409 SH   DFND   2,236,409 0 0
FORTRESS BIOTECH INC COM 34960Q109 808 200,000 SH   DFND   200,000 0 0
FRONTLINE LTD SHS NEW G3682E192 461 70,979 SH   DFND   70,979 0 0
GENCO SHIPPING & TRADING LTD SHS Y2685T131 1,245 180,496 SH   DFND   180,496 0 0
GENERAL MTRS CO COM 37045V100 103,567 3,500,000 SH Call DFND   3,500,000 0 0
GLOBALSTAR INC COM 378973408 3,633 11,838,836 SH   DFND   11,838,836 0 0
GLOBALSTAR INC NOTE 5.750% 4/0 378973AD3 347 519,498 PRN   DFND   519,498 0 0
GLRY STR NW MDIA GRUP HLDG L *W EXP 02/13/202 G39973113 13 225,000 SH   DFND   225,000 0 0
GOLAR LNG PARTNERS LP COM UNIT LPI Y2745C102 1,957 963,969 SH   DFND   963,969 0 0
GREIF INC CL B 397624206 470 11,910 SH   DFND   11,910 0 0
GRUBHUB INC COM 400110102 4,761 65,821 SH   DFND   65,821 0 0
GSX TECHEDU INC SPONSORED ADS 36257Y109 36,045 400,000 SH Put DFND   400,000 0 0
HEALTH SCIENCES ACQ CORP 2 ORD SHS G4411D109 110 10,000 SH   DFND   10,000 0 0
HERTZ GLOBAL HLDGS INC COM 42806J106 3,249 2,926,300 SH Call DFND   2,926,300 0 0
HERTZ GLOBAL HLDGS INC COM 42806J106 1,146 1,032,000 SH Put DFND   1,032,000 0 0
HL ACQUISITIONS CORP *W EXP 06/21/202 G4603R122 373 180,000 SH   DFND   180,000 0 0
HL ACQUISITIONS CORP RIGHT 07/17/2023 G4603R130 114 108,600 SH   DFND   108,600 0 0
HOSTESS BRANDS INC *W EXP 11/04/202 44109J114 2,067 2,520,000 SH   DFND   2,520,000 0 0
HYCROFT MINING HOLDING CORP COM CL A 44862P109 1,513 143,925 SH   DFND   143,925 0 0
HYCROFT MINING HOLDING CORP *W EXP 02/12/202 44862P117 3,140 2,000,000 SH   DFND   2,000,000 0 0
IAC INTERACTIVECORP NEW COM 44891N109 55,458 463,000 SH   DFND   463,000 0 0
IAMGOLD CORP COM 450913108 1,149 300,000 SH   DFND   300,000 0 0
IMMATICS N.V. SHS N44445109 11,141 1,050,000 SH   DFND   1,050,000 0 0
IMMATICS N.V. *W EXP 07/01/202 N44445117 1,750 500,000 SH   DFND   500,000 0 0
IMMUNOMEDICS INC COM 452907108 4,251 50,000 SH   DFND   50,000 0 0
INSPIRED ENTMT INC COM 45782N108 2,416 816,325 SH   DFND   816,325 0 0
INTL GNRL INSURANCE HLDNGS L *W EXP 03/17/202 G4809J114 269 450,000 SH   DFND   450,000 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100 3,292 100,000 SH   DFND   100,000 0 0
IRSA INVERSIONES Y REP S A GLOBL DEP RCPT 450047204 2,757 977,759 SH   DFND   977,759 0 0
IRSA PROPIEDADES COMERCIALES SPONSORED ADR 463588103 3,355 432,165 SH   DFND   432,165 0 0
ISHARES TR JPMORGAN USD EMG 464288281 66,534 600,000 SH Put DFND   600,000 0 0
JPMORGAN CHASE & CO COM 46625H100 3,369 35,000 SH   DFND   35,000 0 0
KADMON HLDGS INC COM 48283N106 666 170,000 SH   DFND   170,000 0 0
KALEYRA INC *W EXP 12/12/202 483379111 130 91,791 SH   DFND   91,791 0 0
KROGER CO COM 501044101 3,391 100,000 SH Call DFND   100,000 0 0
LARIMAR THERAPEUTICS INC COM 517125100 3,339 220,136 SH   DFND   220,136 0 0
LEAP THERAPEUTICS INC COM 52187K101 1,042 526,466 SH   DFND   526,466 0 0
LEGACY ACQUISITION CORP *W EXP 11/30/202 524643111 268 500,000 SH   DFND   500,000 0 0
LEISURE ACQUISITION CORP *W EXP 12/05/201 52539T115 59 125,000 SH   DFND   125,000 0 0
LF CAP ACQUISITION CORP *W EXP 06/22/202 50200K116 810 450,000 SH   DFND   450,000 0 0
MAGELLAN MIDSTREAM PRTNRS LP COM UNIT RP LP 559080106 49,957 1,460,732 SH   DFND   1,460,732 0 0
MAIDEN HOLDINGS LTD SHS G5753U112 9,610 7,876,964 SH   DFND   7,876,964 0 0
MARINUS PHARMACEUTICALS INC COM NEW 56854Q200 12,486 971,718 SH   DFND   971,718 0 0
MEGALITH FINL ACQUISITION CO *W EXP 08/26/202 58518F117 266 400,000 SH   DFND   400,000 0 0
MEGALITH FINL ACQUISITION CO CL A COM 58518F109 105 10,133 SH   DFND   10,133 0 0
MEIRAGTX HOLDINGS PLC COM G59665102 9,063 684,447 SH   DFND   684,447 0 0
METEN EDTECHX ED GROUP LTD *W EXP 03/31/202 G6055H106 26 125,000 SH   DFND   125,000 0 0
MUSTANG BIO INC COM 62818Q104 1,449 460,000 SH   DFND   460,000 0 0
NATIONAL ENERGY SERVICES REU *W EXP 05/05/202 G6375R115 507 723,700 SH   DFND   723,700 0 0
NAVIOS MARITIME CONTAINERS L COM UNIT RP LP Y62151108 2,318 2,235,000 SH   DFND   2,235,000 0 0
NIKOLA CORP COM 654110105 3,972 193,900 SH Call DFND   193,900 0 0
NUVEEN NEW YORK AMT QLT MUNI COM 670656107 185 14,400 SH   DFND   14,400 0 0
ON DECK CAP INC COM 682163100 9,269 5,793,015 SH   DFND   5,793,015 0 0
ONCOSEC MED INC COM 68234L306 270 79,935 SH   DFND   79,935 0 0
ORISUN ACQUISITION CORP COM 68632T109 509 50,000 SH   DFND   50,000 0 0
ORISUN ACQUISITION CORP RIGHT 05/31/2024 68632T125 30 50,000 SH   DFND   50,000 0 0
ORISUN ACQUISITION CORP *W EXP 05/31/202 68632T117 15 50,000 SH   DFND   50,000 0 0
OTONOMY INC COM 68906L105 3,645 900,000 SH   DFND   900,000 0 0
PANACEA ACQUISITION CORP *W EXP 07/07/202 698102118 470 200,000 SH   DFND   200,000 0 0
PANACEA ACQUISITION CORP CL A 698102100 6,719 600,000 SH   DFND   600,000 0 0
PBF LOGISTICS LP UNIT LTD PTNR 69318Q104 128 15,663 SH   DFND   15,663 0 0
PENN VA CORP COM 70788V102 8,714 884,603 SH   DFND   884,603 0 0
PG&E CORP COM 69331C108 33,653 3,583,929 SH   DFND   3,583,929 0 0
PG&E CORP COM 69331C108 470 50,000 SH Call DFND   50,000 0 0
PIERIS PHARMACEUTICALS INC COM 720795103 186 90,000 SH   DFND   90,000 0 0
PROSHARES TR II ULTA BLMBG 2017 74347Y888 5,690 200,000 SH Put DFND   200,000 0 0
PROVENTION BIO INC COM 74374N102 11,025 859,314 SH   DFND   859,314 0 0
ROTH CH ACQUISITION I CO *W EXP 01/28/202 778675116 143 138,750 SH   DFND   138,750 0 0
ROTH CH ACQUISITION I CO COM 778675108 1,841 185,000 SH   DFND   185,000 0 0
SCHULTZE SPL PURP ACQUSTN CO *W EXP 12/31/202 80821R117 156 300,000 SH   DFND   300,000 0 0
SELECTA BIOSCIENCES INC COM 816212104 1,772 714,619 SH   DFND   714,619 0 0
SIERRA ONCOLOGY INC COM NEW 82640U404 1,495 140,156 SH   DFND   140,156 0 0
STRONGBRIDGE BIOPHARMA PLC SHS USD G85347105 3,350 1,595,082 SH   DFND   1,595,082 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105 12,227 828,371 SH   DFND   828,371 0 0
TEEKAY TANKERS LTD CL A Y8565N300 955 88,124 SH   DFND   88,124 0 0
TENZING ACQUISITION CORP *W EXP 02/23/202 G8708A108 102 200,000 SH   DFND   200,000 0 0
TESLA INC COM 88160R101 10,725 25,000 SH Call DFND   25,000 0 0
TESLA INC COM 88160R101 21,451 50,000 SH Put DFND   50,000 0 0
TFF PHARMACEUTICALS INC COM 87241J104 2,173 117,647 SH   DFND   117,647 0 0
TG THERAPEUTICS INC COM 88322Q108 10,658 398,271 SH   DFND   398,271 0 0
TOTTENHAM ACQUISITION I LTD *W EXP 05/06/202 G8959N114 256 542,000 SH   DFND   542,000 0 0
TOTTENHAM ACQUISITION I LTD RIGHT 11/06/2020 G8959N122 70 134,000 SH   DFND   134,000 0 0
TRACON PHARMACEUTICALS INC COM NEW 89237H209 388 75,000 SH   DFND   75,000 0 0
TRIDENT ACQUISITIONS CORP *W EXP 05/09/202 89615T114 734 1,993,750 SH   DFND   1,993,750 0 0
UNIQURE NV SHS N90064101 17,679 480,000 SH   DFND   480,000 0 0
US ECOLOGY INC *W EXP 10/17/202 91734M111 513 105,350 SH   DFND   105,350 0 0
VENTAS INC COM 92276F100 6,294 150,000 SH Call DFND   150,000 0 0
VENTAS INC COM 92276F100 6,294 150,000 SH Put DFND   150,000 0 0
VYNE THERAPEUTICS INC COM NEW 92941V100 9,909 5,968,957 SH   DFND   5,968,957 0 0
WARRIOR MET COAL INC COM 93627C101 3,758 220,000 SH   DFND   220,000 0 0
WELLS FARGO CO NEW COM 949746101 23,510 1,000,000 SH   DFND   1,000,000 0 0
WORLD ACCEP CORP DEL COM 981419104 1,942 18,400 SH   DFND   18,400 0 0
XERIS PHARMACEUTICALS INC NOTE 5.000% 7/1 98422LAA5 14,550 7,500,000 PRN   DFND   7,500,000 0 0
XERIS PHARMACEUTICALS INC COM 98422L107 1,385 233,600 SH   DFND   233,600 0 0
ZILLOW GROUP INC CL A 98954M101 9,139 90,000 SH   DFND   90,000 0 0
ZOGENIX INC COM NEW 98978L204 2,062 115,000 SH   DFND   115,000 0 0