The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| Aclaris Therapeutics, Inc. | Common | 00461U105 | 2,668 | 1,647,214 | SH | SOLE | 1,647,214 | 0 | 0 | ||
| Aduro Biotech Inc | Common | 00739L101 | 11,824 | 5,118,560 | SH | SOLE | 5,118,560 | 0 | 0 | ||
| Akero Therapeutics Inc | Common | 00973Y108 | 14,732 | 591,169 | SH | SOLE | 591,169 | 0 | 0 | ||
| Amyris, Inc | Common | 03236M200 | 43,475 | 10,181,472 | SH | SOLE | 10,181,472 | 0 | 0 | ||
| Arcutis Biotherapeutics Inc | Common | 03969K108 | 38,990 | 1,289,360 | SH | SOLE | 1,289,360 | 0 | 0 | ||
| Arrowhead Pharmaceuticals Inc | Common | 04280A100 | 24,899 | 576,505 | SH | SOLE | 576,505 | 0 | 0 | ||
| Ascendis Pharma A/S | ADR | 04351P101 | 265,886 | 1,797,745 | SH | SOLE | 1,797,745 | 0 | 0 | ||
| Atricure Inc | Common | 04963C209 | 2,903 | 64,573 | SH | SOLE | 64,573 | 0 | 0 | ||
| Aurinia Pharmaceuticals Inc. | Common | 05156V102 | 8,137 | 500,732 | SH | SOLE | 500,732 | 0 | 0 | ||
| Avadel Pharmaceuticals PLC | ADR | 05337M104 | 28,491 | 3,526,093 | SH | SOLE | 3,526,093 | 0 | 0 | ||
| Avrobio Inc | Common | 05455M100 | 4,426 | 253,625 | SH | SOLE | 253,625 | 0 | 0 | ||
| Black Diamond Therapeutics Inc | Common | 09203E105 | 6,339 | 150,349 | SH | SOLE | 150,349 | 0 | 0 | ||
| Calliditas Therapeutics AB | SPONSORED ADS | 13124Q106 | 13,456 | 580,000 | SH | SOLE | 580,000 | 0 | 0 | ||
| Celldex Therapeutics Inc | Common | 15117B202 | 20,800 | 1,600,000 | SH | SOLE | 1,600,000 | 0 | 0 | ||
| Codexis, Inc | Common | 192005106 | 17,030 | 1,493,903 | SH | SOLE | 1,493,903 | 0 | 0 | ||
| Constellation Pharmaceutical | Common | 210373106 | 4,216 | 140,298 | SH | SOLE | 140,298 | 0 | 0 | ||
| Crinetics Pharmaceuticals Inc | Common | 22663K107 | 40,587 | 2,316,628 | SH | SOLE | 2,316,628 | 0 | 0 | ||
| Cymabay Therapeutics Inc | Common | 23257D103 | 7,292 | 2,089,356 | SH | SOLE | 2,089,356 | 0 | 0 | ||
| DBV Technologies S.A. | ADR | 23306J101 | 1,185 | 269,995 | SH | SOLE | 269,995 | 0 | 0 | ||
| Eiger BioPharmaceuticals Inc | Common | 28249U105 | 17,196 | 1,791,257 | SH | SOLE | 1,791,257 | 0 | 0 | ||
| Galmed Pharmaceuticals Ltd | SHS | M47238106 | 4,111 | 860,103 | SH | SOLE | 860,103 | 0 | 0 | ||
| Genetron Holdings Ltd | ADS | 37186H100 | 76,522 | 6,339,860 | SH | SOLE | 6,339,860 | 0 | 0 | ||
| Homology Medicines, Inc. | Common | 438083107 | 13,302 | 875,696 | SH | SOLE | 875,696 | 0 | 0 | ||
| IGM Biosciences Inc | Common | 449585108 | 8,722 | 119,480 | SH | SOLE | 119,480 | 0 | 0 | ||
| Immunovant Inc | Common | 45258J102 | 19,480 | 800,000 | SH | SOLE | 800,000 | 0 | 0 | ||
| Iveric Bio Inc | Common | 46583P102 | 30,429 | 5,966,527 | SH | SOLE | 5,966,527 | 0 | 0 | ||
| Kadmon Holdings Inc | Common | 48283N106 | 27,381 | 5,347,768 | SH | SOLE | 5,347,768 | 0 | 0 | ||
| Kala Pharmaceuticals, Inc. | Common | 483119103 | 8,270 | 786,883 | SH | SOLE | 786,883 | 0 | 0 | ||
| KalVista Pharmaceuticals Inc. | Common | 483497103 | 17,869 | 1,476,796 | SH | SOLE | 1,476,796 | 0 | 0 | ||
| Kiniksa Pharmaceuticals | Common | G5269C101 | 29,343 | 1,151,622 | SH | SOLE | 1,151,622 | 0 | 0 | ||
| Kura Oncology Inc | Common | 50127T109 | 17,115 | 1,050,000 | SH | SOLE | 1,050,000 | 0 | 0 | ||
| Larimar Therapeutics Inc | Common | 517125100 | 10,276 | 799,662 | SH | SOLE | 799,662 | 0 | 0 | ||
| Legend Biotech Corp Sponsored | SPONSORED ADS | 52490G102 | 151,301 | 3,555,007 | SH | SOLE | 3,555,007 | 0 | 0 | ||
| Matinas Biopharma Hldgs Inc | Common | 576810105 | 8,719 | 11,279,323 | SH | SOLE | 11,279,323 | 0 | 0 | ||
| MEI Pharma Inc | Common | 55279B202 | 4,469 | 1,082,080 | SH | SOLE | 1,082,080 | 0 | 0 | ||
| Menlo Therapeutics Inc. | Common | 586858102 | 6,304 | 3,643,824 | SH | SOLE | 3,643,824 | 0 | 0 | ||
| Mereo Biopharma Group PLC | ADS | 589492107 | 2,381 | 778,000 | SH | SOLE | 778,000 | 0 | 0 | ||
| Myokardia Inc | Common | 62857M105 | 15,296 | 158,310 | SH | SOLE | 158,310 | 0 | 0 | ||
| New Frontier Health Corp | Ord Shs | G6461G106 | 118,404 | 14,300,000 | SH | SOLE | 14,300,000 | 0 | 0 | ||
| Orchard Therapeutics plc | ADS | 68570P101 | 7,954 | 1,325,736 | SH | SOLE | 1,325,736 | 0 | 0 | ||
| Passage Bio Inc | Common | 702712100 | 60,935 | 2,229,587 | SH | SOLE | 2,229,587 | 0 | 0 | ||
| Precision Biosciences Inc | Common | 74019P108 | 1,168 | 140,255 | SH | SOLE | 140,255 | 0 | 0 | ||
| Revolution Medicines Inc | Common | 76155X100 | 6,299 | 199,518 | SH | SOLE | 199,518 | 0 | 0 | ||
| Rocket Pharmaceuticals Inc | Common | 77313F106 | 18,013 | 860,648 | SH | SOLE | 860,648 | 0 | 0 | ||
| Sage Therapeutics Inc | Common | 78667J108 | 14,269 | 343,179 | SH | SOLE | 343,179 | 0 | 0 | ||
| Selecta Biosciences Inc | Common | 816212104 | 6,406 | 2,255,781 | SH | SOLE | 2,255,781 | 0 | 0 | ||
| Sierra Oncology, Inc | Common | 82640U107 | 23,197 | 1,917,074 | SH | SOLE | 1,917,074 | 0 | 0 | ||
| Sinovac Biotech Ltd. | SHS | P8696W104 | 38,173 | 5,900,000 | SH | SOLE | 5,900,000 | 0 | 0 | ||
| Tricida, Inc. | Common | 89610F101 | 4,803 | 174,764 | SH | SOLE | 174,764 | 0 | 0 | ||
| Verastem Inc | Common | 92337C104 | 7,980 | 4,639,535 | SH | SOLE | 4,639,535 | 0 | 0 | ||
| Verona Pharma PLC | ADS | 925050106 | 6,987 | 1,492,951 | SH | SOLE | 1,492,951 | 0 | 0 | ||
| Zai Lab Limited | ADR | 98887Q104 | 10,029 | 122,107 | SH | SOLE | 122,107 | 0 | 0 | ||
| Zogenix Inc | Common | 98978L204 | 17,787 | 658,523 | SH | SOLE | 658,523 | 0 | 0 | ||
| Zymeworks Inc | Common | 98985W102 | 26,481 | 734,161 | SH | SOLE | 734,161 | 0 | 0 | ||