The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| ADVERUM BIOTECHNOLOGIES INC | COM | 00773U108 | 721 | 70,000 | SH | DFND | 70,000 | 0 | 0 | ||
| AKOUOS INC | COM | 00973J101 | 19,357 | 846,397 | SH | DFND | 846,397 | 0 | 0 | ||
| AMERICAN WELL CORP | CL A | 03044L105 | 7,361 | 248,352 | SH | DFND | 248,352 | 0 | 0 | ||
| BLUEBIRD BIO INC | COM | 09609G100 | 432 | 8,000 | SH | DFND | 8,000 | 0 | 0 | ||
| BLUEPRINT MEDICINES CORP | COM | 09627Y109 | 603 | 6,500 | SH | DFND | 6,500 | 0 | 0 | ||
| CORVUS PHARMACEUTICALS INC | COM | 221015100 | 2,339 | 583,232 | SH | DFND | 583,232 | 0 | 0 | ||
| FREELINE THERAPEUTICS HLDGS | SPONSORED ADS | 35655L107 | 20,673 | 1,324,364 | SH | DFND | 1,324,364 | 0 | 0 | ||
| G1 THERAPEUTICS INC | COM | 3621LQ109 | 970 | 84,000 | SH | DFND | 84,000 | 0 | 0 | ||
| GLOBAL BLOOD THERAPEUTICS IN | COM | 37890U108 | 882 | 16,000 | SH | DFND | 16,000 | 0 | 0 | ||
| GLOBAL BLOOD THERAPEUTICS IN | COM | 37890U108 | 26 | 10,000 | SH | Call | DFND | 10,000 | 0 | 0 | |
| INOZYME PHARMA INC | COM | 45790W108 | 26,529 | 1,009,117 | SH | DFND | 1,009,117 | 0 | 0 | ||
| KEROS THERAPEUTICS INC | COM | 492327101 | 21,964 | 569,458 | SH | DFND | 569,458 | 0 | 0 | ||
| KEZAR LIFE SCIENCES INC | COM | 49372L100 | 1,194 | 246,643 | SH | DFND | 246,643 | 0 | 0 | ||
| LARIMAR THERAPEUTICS INC | COM | 517125100 | 22,985 | 1,515,148 | SH | DFND | 1,515,148 | 0 | 0 | ||
| LIVONGO HEALTH INC | COM | 539183103 | 510 | 3,640 | SH | DFND | 3,640 | 0 | 0 | ||
| MYOKARDIA INC | COM | 62857M105 | 954 | 7,000 | SH | DFND | 7,000 | 0 | 0 | ||
| ORCHARD THERAPEUTICS PLC | ADS | 68570P101 | 12,047 | 2,931,185 | SH | DFND | 2,931,185 | 0 | 0 | ||
| OVID THERAPEUTICS INC | COM | 690469101 | 3,548 | 618,092 | SH | DFND | 618,092 | 0 | 0 | ||
| PLIANT THERAPEUTICS INC | COM | 729139105 | 53,279 | 2,352,291 | SH | DFND | 2,352,291 | 0 | 0 | ||
| PRECISION BIOSCIENCES INC | COM | 74019P108 | 6,251 | 1,014,840 | SH | DFND | 1,014,840 | 0 | 0 | ||
| REPARE THERAPEUTICS INC | COM | 760273102 | 77,863 | 2,530,494 | SH | DFND | 2,530,494 | 0 | 0 | ||
| ULTRAGENYX PHARMACEUTICAL IN | COM | 90400D108 | 616 | 7,500 | SH | DFND | 7,500 | 0 | 0 | ||