The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
AFFIMED N V COM N01045108 4,352 942,989 SH   SOLE   942,989 0 0
AGILENT TECHNOLOGIES INC COM 00846U101 44 500 SH   SOLE   500 0 0
ALBIREO PHARMA INC COM 01345P106 2,067 78,029 SH   SOLE   78,029 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206 33,120 4,786,101 SH   SOLE   4,786,101 0 0
AMNEAL PHARMACEUTICALS INC COM STK CL A 03168L105 4,220 886,587 SH   SOLE   886,587 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106 13,748 420,932 SH   SOLE   420,932 0 0
ASCENDIS PHARMA A S SPONSORED ADR 04351P101 32,589 220,344 SH   SOLE   220,344 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108 29,732 562,151 SH   SOLE   562,151 0 0
AURINIA PHARMACEUTICALS INC COM 05156V102 8,910 548,325 SH   SOLE   548,325 0 0
AUTOLUS THERAPEUTICS PLC SPON ADS 05280R100 4,142 258,360 SH   SOLE   258,360 0 0
BIOCRYST PHARMACEUTICALS INC COM 09058V103 23,100 4,847,792 SH   SOLE   4,847,792 0 0
BIODELIVERY SCIENCES INTL IN COM 09060J106 2,544 583,504 SH   SOLE   583,504 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 32,773 448,264 SH   SOLE   448,264 0 0
BRISTOL-MYERS SQUIBB CO RIGHT 12/30/2030 110122140 3 6,000 SH   SOLE   6,000 0 0
BURNING ROCK BIOTECH LTD SPONSORED ADS 12233L107 810 30,000 SH   SOLE   30,000 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 9,265 712,698 SH   SOLE   712,698 0 0
CHEMOCENTRYX INC COM 16383L106 2,350 40,842 SH   SOLE   40,842 0 0
COMMUNITY HEALTH SYS INC NEW COM 203668108 1,482 492,272 SH   SOLE   492,272 0 0
CONCERT PHARMACEUTICALS INC COM 206022105 2,318 232,983 SH   SOLE   232,983 0 0
CYCLERION THERAPEUTICS INC COM 23255M105 1,464 247,663 SH   SOLE   247,663 0 0
CYTOKINETICS INC COM NEW 23282W605 3,340 141,700 SH   SOLE   141,700 0 0
DANAHER CORPORATION COM 235851102 19,090 107,857 SH   SOLE   107,857 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 25,002 418,652 SH   SOLE   418,652 0 0
DEXCOM INC COM 252131107 2,704 6,670 SH   SOLE   6,670 0 0
DICERNA PHARMACEUTICALS INC COM 253031108 3,274 128,905 SH   SOLE   128,905 0 0
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201 867 97,800 SH   SOLE   97,800 0 0
EIGER BIOPHARMACEUTICALS INC COM 28249U105 470 49,008 SH   SOLE   49,008 0 0
ENSIGN GROUP INC COM 29358P101 17,904 427,307 SH   SOLE   427,307 0 0
FATE THERAPEUTICS INC COM 31189P102 18,227 531,258 SH   SOLE   531,258 0 0
FLUIDIGM CORP DEL COM 34385P108 1,876 467,923 SH   SOLE   467,923 0 0
GLAXOSMITHKLINE PLC SPONSORED ADR 37733W105 9,270 227,263 SH   SOLE   227,263 0 0
HCA HEALTHCARE INC COM 40412C101 2,951 30,400 SH   SOLE   30,400 0 0
HESKA CORP COM RESTRC NEW 42805E306 26,111 280,256 SH   SOLE   280,256 0 0
HORIZON THERAPEUTICS PUB LTD SHS G46188101 53,064 954,738 SH   SOLE   954,738 0 0
IMMUNOVANT INC COM 45258J102 299 12,266 SH   SOLE   12,266 0 0
KALVISTA PHARMACEUTICALS INC COM 483497103 1,087 89,806 SH   SOLE   89,806 0 0
KINIKSA PHARMACEUTICALS LTD COM CL A G5269C101 2,082 81,700 SH   SOLE   81,700 0 0
LIQUIDIA TECHNOLOGIES INC COM 53635D202 7,239 859,724 SH   SOLE   859,724 0 0
MODEL N INC COM 607525102 11,845 340,764 SH   SOLE   340,764 0 0
MOMENTA PHARMACEUTICALS INC COM 60877T100 4,137 124,338 SH   SOLE   124,338 0 0
MYOKARDIA INC COM 62857M105 6,821 70,594 SH   SOLE   70,594 0 0
MYOVANT SCIENCES LTD COM G637AM102 15,683 760,551 SH   SOLE   760,551 0 0
OSMOTICA PHARMACEUTICALS PLC SHS G6S41R101 532 79,037 SH   SOLE   79,037 0 0
OTONOMY INC COM 68906L105 2,176 601,163 SH   SOLE   601,163 0 0
OXFORD IMMUNOTEC GLOBAL PLC ORD SHS G6855A103 4,552 350,138 SH   SOLE   350,138 0 0
PACIRA BIOSCIENCES COM 695127100 6,960 132,655 SH   SOLE   132,655 0 0
PENNANT GROUP INC COM 70805E109 2,318 102,568 SH   SOLE   102,568 0 0
PROTARA THERAPEUTICS INC COM STK 74365U107 1,358 46,310 SH   SOLE   46,310 0 0
PROTHENA CORP PLC SHS G72800108 1,592 152,213 SH   SOLE   152,213 0 0
QIAGEN NV SHS NEW N72482123 3,530 82,466 SH   SOLE   82,466 0 0
RADIUS HEALTH INC COM NEW 750469207 3,000 220,110 SH   SOLE   220,110 0 0
SANOFI SPONSORED ADR 80105N105 2,541 49,778 SH   SOLE   49,778 0 0
SAREPTA THERAPEUTICS INC COM 803607100 11,501 71,731 SH   SOLE   71,731 0 0
SCPHARMACEUTICALS INC COM 810648105 1,821 247,419 SH   SOLE   247,419 0 0
SESEN BIO INC COM 817763105 1,440 2,000,000 SH   SOLE   2,000,000 0 0
SOLID BIOSCIENCES INC COM 83422E105 1,193 407,024 SH   SOLE   407,024 0 0
TARO PHARMACEUTICAL INDS LTD SHS M8737E108 6,993 105,169 SH   SOLE   105,169 0 0
TELIGENT INC NEW COM NEW 87960W203 859 354,998 SH   SOLE   354,998 0 0
TG THERAPEUTICS INC COM 88322Q108 48,725 2,501,272 SH   SOLE   2,501,272 0 0
UNIQURE NV SHS N90064101 1,033 22,928 SH   SOLE   22,928 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102 28,154 232,676 SH   SOLE   232,676 0 0
VAPOTHERM INC COM 922107107 2,944 71,819 SH   SOLE   71,819 0 0
XOMA CORP DEL COM NEW 98419J206 1,266 64,056 SH   SOLE   64,056 0 0
ZOGENIX INC COM NEW 98978L204 27,201 1,007,083 SH   SOLE   1,007,083 0 0
ZYMEWORKS INC COM 98985W102 1,443 40,000 SH   SOLE   40,000 0 0
AIR LEASE CORP PUT 00912X952 278 200 SH   SOLE   200 0 0
ALIGN TECHNOLOGY INC PUT 016255951 68 100 SH   SOLE   100 0 0
AMARIN CORP PLC CALL 023111906 2,831 10,803 SH   SOLE   10,803 0 0
SPDR S&P 500 ETF TR PUT 78462F953 7,387 3,400 SH   SOLE   3,400 0 0
SELECT SECTOR SPDR TR PUT 81369Y959 3,266 800 SH   SOLE   800 0 0
ZOGENIX INC CALL 98978L904 61 55 SH   SOLE   55 0 0